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Experimental investigation on evolution of a split multi-wavelength bright-dark pulse in a mode-locked thulium-doped fiber laser

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Optoelectronics Letters 2022年第12期18卷 717-722页

作者： wang Xiaofa Wang Jie DUAN Xianyi Chongqing Key Laboratory of Photoelectronic Information Sensing and Transmitting Technology School of Optoelectronic EngineeringChongqing University of Posts and TelecommunicationsChongqing400065China

We report the experimental observation of evolving phenomenon of a split multi-wavelength bright-dark pulse in the nonlinear amplifying loop mirror(NALM)-based mode-locked thulium-doped fiber laser(TDFL) with a figure-eight configuration. Bright-dark pulse with 10 wavelengths was successfully obtained at the pump power of 3 W. The time interval between the bright and dark pulses was discovered not only increasing linearly with the pump power but also approximately equaling to the reciprocal of modulation frequency of radio frequency(RF) spectrum. Moreover, we also observed that the spectrum of split multi-wavelength bright-dark pulse can further present up to 13 wavelengths.

关键词： pulse fiber pump

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王阶运用补法治疗冠心病经验

中华中医药杂志 2021年第5期36卷 2731-2733页

作者：胡骏王阶中国中医科学院广安门医院北京100053 中国中医科学院广安门医院心血管科北京100053

冠心病是全球性的重大健康问题,王阶教授认为冠心病主要病机为"痰瘀滞虚",而"虚"的病机最为主要,贯穿了冠心病发生发展的全程,包含了气虚、肾虚、神损等不同的方面和程度,故临证之时应以补法为核心。文章梳理王阶教授运用补法治疗冠心... 详细信息

冠心病是全球性的重大健康问题,王阶教授认为冠心病主要病机为"痰瘀滞虚",而"虚"的病机最为主要,贯穿了冠心病发生发展的全程,包含了气虚、肾虚、神损等不同的方面和程度,故临证之时应以补法为核心。文章梳理王阶教授运用补法治疗冠心病经验,将其总结为4点,即恒用补气通络之法,善用补肾益精之法,妙用调补心神之药、酌用血肉有情之品。

关键词：补法冠心病王阶

Experimental Studies on Cyclic Shear Behavior of Steel-Clay Interface Under Constant Normal Load

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China Ocean Engineering 2023年第3期37卷 519-524页

作者： YU Shi-wen Wang Jie LIU Jun-wei wang Teng School of Petroleum Engineering China University of Petroleum(East China)Qingdao 266580China China Communications Third Harbor Engineering Co. Ltd.ShanghaiChina School of Civil Engineering Qingdao University of TechnologyQingdao 266520China

The degradation of the shear stress between pile-clay interface caused by undrained cyclic jacking affects the jacking force.A series of large displacement monotonic shear,cyclic shear and post-cyclic monotonic steel plate-clay interface shear te sts were performed under the constant normal load(CNL)condition to inve stigate the effects of normal stre ss,cyclic amplitude,and number of cycles on a steel plate-clay interface using the GDS multi-function interface shear tester.Based on the experimental results,in monotonic shear tests,change of shear stress took place in the specimen,the shear stress rapidly reached the peak value at shear displacement of 1 mm,and then abruptly decreased to the residual value.In cyclic shear te sts,accumulated displacement was a better parameter to describe the soil degradation characteristics,and the degradation degree of shear stress became greater with the increasing of normal stress and accumulated displacement.Shear stress in post-cyclic monotonic shear tests did not generate a peak value and was lower than that in monotonic shear tests under the same normal stress.The soil was completely disturbed and reached the residual strength when the cumulative displacement approached 6 m.An empirical equation to evaluate shear stress degradation mechanism was formulated and the procedure of parameter identification was presented.

关键词： cyclic shear steel-clay interface constant normal load cumulative displacement residual strength

Structural characterization,in vivo toxicity and biological activity of two new pyro-type diterpenoid alkaloids derived from 3-acetylaconitine

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Journal of Integrative Medicine 2023年第3期21卷 302-314页

作者： Yu-jie wang Yan wang Pei Tao School of Ethnic Medicine Chengdu University of Traditional Chinese MedicineChengdu 611137Sichuan ProvinceChina School of Pharmacy Chengdu University of Traditional Chinese MedicineChengdu 611137Sichuan ProvinceChina

Objective:The transformations that occur in diterpenoid alkaloids during the process of sand frying for Chinese herbal medicine preparation have yet to be clarified.This study investigated the structural changes that take place in 3-acetylaconitine during a simulation of heat-processing and evaluated the toxicity and biological activity of the pyrolysis products.Methods:The diterpenoid alkaloid 3-acetylaconitine was heated at 180°C for 15 min to simulate the process of sand frying.The pyrolysis products were separated using column chromatography,and their structures were investigated using high-resolution electrospray ionization mass spectroscopy and nuclear magnetic resonance spectroscopy.Further,in vivo cardiotoxicity and acute toxicity of 3-acetylaconitine and its pyrolysis products were compared,and the aconitine-induced arrhythmia model was employed to evaluate the antiarrhythmic effect of the pyrolysis products.Results:Two new diterpenoid alkaloids,pyroacetylaconitine and 16-epi-pyroacetylaconitine,a pair of epimers at C-16,were isolated.After comparing the structures of these compounds,possible transformation pathways were proposed.Compared with the prototype compound,3-acetylaconitine,the cardiotoxicity and acute toxicity of the heat-transformed products were significantly decreased.In the biological activity assay,the two pyrolysis products exhibited an effective increase in ventricular premature beat latency,a reduction in the occurrence of ventricular tachycardia,as well as an increase in the rate of arrhythmia inhibition,implying strong antiarrhythmic activity.Conclusion:Compared with 3-acetylaconitine,its pyrolysis products displayed lower toxicity and good antiarrhythmic effects;thus,they have potential for being developed into antiarrhythmic medicines.

关键词： 3-Acetylaconitine Acute toxicity Antiarrhythmic agents 16-Epi-pyroacetylaconitine Pyroacetylaconitine Processing

Cure for Acquired Immunodeficiency Syndrome——A Global Battle

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Chinese Journal of Integrative Medicine 2014年第2期20卷 83-87页

作者： Wang Jie Guang'anmen Hospital China Academy of Chinese Medical Sciences

Acquired immu- nodeficiency syndrome （AIDS） is caused by the human immunodeficiency virus （HIV）. It has ravaged everywhere in the world and has seriously ieopardized people＇s physical and mental health and their ... 详细信息

关键词： AIDS HIV HAART Cure for Acquired Immunodeficiency Syndrome A Global Battle

Rejuvenating the Immune System:Insights for Anti-Neurodegeneration Strategies

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Neuroscience Bulletin 2022年第1期38卷 107-109页

作者： jie Liu Yan-Jiang wang Department of Neurology Daping HospitalThird Military Medical UniversityChongqing400042China Chongqing Key Laboratory of Ageing and Brain Diseases Chongqing400042China Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of SciencesShanghai200031China

Aging is the primary risk factor for various chronic disorders,especially neurodegeneration diseases,including Alzheimer’s disease(AD)and Parkinson’s disease(PD).It has been estimated that about one in ten individuals aged>65 are affected by AD,and this prevalence continues to increase with the aging of the population[1],causing a heavy burden on the family and society.As the aging population grows progressively around the globe,drug discoveries targeting the aging process have become a hot spot[2].

关键词： degeneration Immune diseases

The Roles of Barotropic Instability and the Beta Effect in the Eyewall Evolution of Tropical Cyclones

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Advances in Atmospheric Sciences 2022年第11期39卷 1800-1815页

作者： jie JIANG Yuqing wang Department of Atmospheric Sciences University of Hawaii at Manoa HonoluluHawaii 96822USA International Pacific Research Center and Department of Atmospheric Sciences University of Hawaii at Manoa HonoluluHawaii 96822USA

Diabatic heating by convection in the eyewall often produces an annular region of high potential vorticity(PV)around the relatively low PV eye in a strong tropical cyclone(TC).Such a PV ring is barotropically unstable and can encourage the exponential growth of PV waves.In this study,such instability and the subsequent nonlinear evolution of three TC-like vortices having PV rings with different degrees of hollowness on an f-plane are first examined using an unforced,inviscid shallow-water-equation model.Results show that the simulated eyewalls evolve similarly to those in the nondivergent barotropic model.It is also found that the polygonal eyewall structure can be decomposed into vortex Rossby waves(VRWs)of different wavenumbers with different amplitudes,allowing for wave-wave interactions to produce complicated behaviors of mesovortices in the TC eyewall.The same set of PV rings has been examined on a beta-plane.Although the beta effect has been rendered unimportant to the eyewall evolution due to the relatively small scale of the inner-core circulation,this study shows that the beta effect may erode the coherent structure of mesovortices in the eyewall of an initially hollow PV-ring vortex.Mesovortices modeled on the beta-plane with a greater beta parameter tend to experience an earlier breakdown and enhanced radial gradients of the basic-state(azimuthally mean)angular velocity,followed by wave-wave,wave-flow interactions,leading to earlier merger and axisymmetrization processes.This result implies that the beta effect could be one of the forcings that shorten the lifetime of quasi-steady mesovortices in the eyewall of real TCs.

关键词： tropical cyclones vortex rossby waves barotropic instability Beta effect

Stochastic fatigue damage model for concrete under complex stress states

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Science China(Technological Sciences) 2022年第11期65卷 2641-2648页

作者： wang YanPeng LI jie School of Civil and Transportation Engineering Guangdong University of TechnologyGuangzhou 510006China School of Civil Enginering Tongji UniversityShanghai 200092China

This paper presents a stochastic fatigue damage model for concrete subjected to complex stress states.A constitutive framework considering the tensile and shear damage mechanisms and elastic and plastic energy dissipations is employed.The damage law is established through a multiscale analysis of the damage evolution mechanism.Validation results against test data show that the model can effectively predict the static strength,stress-strain curve,fatigue life,and scattering range of concrete under various multidimensional loading scenarios.

关键词： concrete fatigue stochastic damageevolution complex stress states multiscale

GNSS array receiver faced with overloaded interferences:anti-jamming performance and the incident directions of interferences

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Journal of Systems Engineering and Electronics 2023年第2期34卷 335-341页

作者： Wang Jie LIU Wenxiang CHEN Feiqiang LU Zukun OU Gang College of Electronic Science National University of Defense TechnologyChangsha 410073China College of Electronic Engineering National University of Defense TechnologyHefei 230031China

Anti-jamming solutions based on antenna arrays enhance the anti-jamming ability and the robustness of global navigation satellite system(GNSS)receiver remarkably.However,the performance of the receiver will deteriorate significantly in the overloaded interferences scenario.We define the overloaded interferences scenario as where the number of interferences is more than or equal to the number of antenna arrays elements.In this paper,the effect mechanism of interferences with different incident directions is found by studying the anti-jamming performance of the adaptive space filter.The theoretical analysis and conclusions,which are first validated through numerical examples,reveal the relationships between the optimal weight vector and the eigenvectors of the input signal autocorrelation matrix,the relationships between the interference cancellation ratio(ICR),the signal to interference and noise power ratio(SINR)of the adaptive space filter output and the number of interferences,the eigenvalues of the input signal autocorrelation matrix.In addition,two simulation experiments are utilized to further corroborate the theoretical findings through soft anti-jamming receiver.The simulation results match well with the theoretical analysis results,thus validating the effect mechanism of overloaded interferences.The simulation results show that,for a four elements circular array,the performance difference is up to 19 dB with different incident directions of interferences.Anti-jamming performance evaluation and jamming deployment optimization can obtain more accurate and efficient results by using the conclusions.

关键词： antenna arrays anti-jamming overloaded interferences incident direction