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Experimental study of a controlled variable double-baffle distortion generator engine test rig

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Chinese Journal of Aeronautics 2018年第9期31卷 1880-1893页

作者： Aiguo xia Xudong huang Wei TUO ming ZHOU School of Aerospace Engineering Tsinghua University Beijing Aeronautical Technology Research Center

In order to explore the total-pressure distortion test assessment method for a turbofan engine, a Controlled Variable Double-Baffle Distortion Generator(CVDBDG) with a horizontal symmetry moving form was developed, which can adjust the steady-state and time–variant distortion separately in real time. The inlet total-pressure distortion test was conducted on an afterburner turbofan engine. The distortion parameters of CVDBDG and the instability characteristics of the engine were measured. The experimental data were modeled and analyzed by using back propagation artificial neural networks, and the work envelope of CVDBDG was obtained. Based on the analysis of the data on the engine’s instability, the properties of CVDBDG used for the stability assessment were preliminarily evaluated. The results show that CVDBDG can simulate both steady-state and time–variant distortions simultaneously in a range determined by three *** the condition of symmetric double baffles, a critical depth of insertion exists, beyond which the symmetric baffles will generate an asymmetric flow field. In the case of double baffles, compared to a single baffle, the engine exhibited different instability characteristics. Based on CVDBDG, it is expected that more efficient engine stability and durability assessment methods can be developed.

关键词： Distortion generator Engine stability Inlet flow Inlet total-pressure distortion Turbofan engines

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基于三基色LED的线性调光混合照明

中国光学（中英文） 2024年第1期17卷 108-117页

作者：黄涛夏振平彭子雄刘宇杰李超超顾敏明苏州科技大学电子与信息工程学院江苏苏州215009

为提供高品质、智能健康的照明光源,基于三基色LED光源构建了线性调光混合照明系统,并提出一种调光调色的优化方法。混合光源的光色度和光强度分别用色温和明度等级来设定,使得混合照明效果更加符合“人因照明”的需求。在系统的智能优... 详细信息

为提供高品质、智能健康的照明光源,基于三基色LED光源构建了线性调光混合照明系统,并提出一种调光调色的优化方法。混合光源的光色度和光强度分别用色温和明度等级来设定,使得混合照明效果更加符合“人因照明”的需求。在系统的智能优化配光过程中,将色温转化为CIE u′v′色度坐标,明度转化为亮度,使优化计算更加精确。该系统采用线性调光的方式,既能有效避免混合光源闪烁带来的健康安全问题,配合优化算法又有效解决了线性调光色度漂移大的问题。实验结果表明,在2000 K~8000 K的色温范围内,混合照明系统混合光的色度稳定性保持在1阶CIE u′v′圆内,在对应色温下的整个光强度调节范围内无可察觉的色差。采用线性调光方式在保持光色度稳定上比脉冲宽度调光方式效果更佳。理论探究和实验结果表明该混光照明系统简易可行,具有较高的实用价值。

关键词：三基色LED 混合照明线性调光人因照明色差 CIE u′v′圆

低轨星座传感器资源调度的自主任务规划建模方法

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空间控制技术与应用 2024年第4期50卷 9-16页

作者：王淑一黄盘兴雷冰瑶夏维北京控制工程研究所北京100094 空间智能控制技术全国重点实验室北京100094 合肥工业大学合肥230009

低轨星座传感器资源的优化调度是复杂多约束下的任务规划问题,为了满足多个运动目标全程跟踪与监视的资源实时优化调度需求,提出一种星上自主快速求解的规划模型.在对自主任务规划问题进行详细建模的基础上,考虑各项约束条件与优化因素... 详细信息

低轨星座传感器资源的优化调度是复杂多约束下的任务规划问题,为了满足多个运动目标全程跟踪与监视的资源实时优化调度需求,提出一种星上自主快速求解的规划模型.在对自主任务规划问题进行详细建模的基础上,考虑各项约束条件与优化因素,将原问题转化成简易的0-1线性整数规划模型,并构建多目标跟踪试验场景对所提方法进行了仿真验证.仿真结果表明,基于简易规划模型的资源调度可实现多目标的全程跟踪与监视.

关键词：低轨星座传感器资源调度自主任务规划线性整数规划模型

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川西高寒草甸植物功能属性与环境因子的关系研究

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草业学报 2024年第9期33卷 28-39页

作者：和阳一丹陈昌明黄晓霞施国美和克俭云南大学地球科学学院国际喀斯特联合研究中心云南省地理研究所云南昆明650091 云南农业大学水利学院云南昆明650201

作为连接植物和环境的桥梁,植物功能属性反映了植物对环境的适应以及植物内部不同功能之间的关系。本研究基于群落、植物功能属性和生境调查结果,分析了川西高寒草甸植物功能属性与环境因子的关系。研究发现:高寒草甸植物的功能属性之... 详细信息

作为连接植物和环境的桥梁,植物功能属性反映了植物对环境的适应以及植物内部不同功能之间的关系。本研究基于群落、植物功能属性和生境调查结果,分析了川西高寒草甸植物功能属性与环境因子的关系。研究发现:高寒草甸植物的功能属性之间主要呈现协调关系,特别是在能量、物质和生物量分配等方面。此外,根冠比(RSR)与茎比例(SMF)、繁殖器官比例(RPMF)之间存在明显的权衡关系。当面临胁迫和干扰时,高寒草甸植物可能采取将更多资源投入根部生长和发育,较少资源分配给茎和繁殖器官,但同时保证分配给叶片进行光合作用资源的策略。高寒草甸植物以矮化、减少茎、叶和繁殖器官比例(SMF、LMF和RPMF)、降低比根长(SRL),增加叶片干物质含量(LDMC)和比叶面积(SLA)、提高根冠比(RSR)、增加地下生物量(IUGB)和根干物质含量(RDMC)等一系列策略适应低温、强辐射和水分不足等环境胁迫。人为干扰会导致高寒草甸植物的高度(VH)、茎比例(SMF)、茎干物质含量(SDMC)、繁殖器官比例(RPMF)、繁殖器官干物质含量(RPDMC)、叶比例(LMF)、比根长(SRL)和地上生物量(IAGB)减小,而根冠比(RSR)增加。然而,高寒草甸植物功能属性的变化主要受环境因素影响,受人为干扰的影响相对较小。这些研究结果为理解植物如何通过调整功能属性来适应环境变化,以及制定有效的草甸保护和管理策略提供了重要的科学依据。

关键词：高寒草甸植物功能属性人为干扰属性权衡环境适应

Achievements and challenges of primate conservation in China

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Zoological Research(Diversity and Conservation) 2024年第1期1卷 66-74页

作者： Bao-Guo Li He Zhang ming Li Xue-Long Jiang Peng-Fei Fan Jiang Zhou Song-Tao Guo xiao-Guang Qi Jin-Hua Li Ji-Qi Lu Dong-Po xia Liang-Wei Cui Zuo-Fu xiang Qi-Hai Zhou Zhi-Pang huang Cheng-ming huang Wen xiao Hui-Jian Hu Zhi-Xin Zhou ming-Yong Chen Da-Yong Li Peng-Lai Fan Yin Yang Ru-Liang Pan Shaanxi Key Laboratory for Animal Conservation College of Life SciencesNorthwest UniversityXi’anShaanxi 710069China Jiangxi Provincial Key Laboratory of Conservation Biology College of ForestryJiangxi Agricultural UniversityNanchangJiangxi 330045China Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China State Key Laboratory of Genetic Resources and Evolution Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650201China School of Life Sciences Sun Yat-sen UniversityGuangzhouGuangdong 510275China School of Karst Science Guizhou Normal UniversityGuiyangGuizhou 550025China International Collaborative Research Center for huangshan Biodiversity and Tibetan Macaque Behavioral Ecology Anhui UniversityHefeiAnhui 230601China Institute of Biodiversity and Ecology Zhengzhou UniversityZhengzhouHenan 450001China Key Laboratory for Conserving Wildlife with Small Populations in Yunnan Southwest Forestry UniversityKunmingYunnan 650224China College of Life Sciences and Technology Central South University of Forestry and TechnologyChangshaHunan 410004China Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection(Ministry of Education) Guangxi Normal UniversityGuilinGuangxi 541004China International Centre of Biodiversity and Primate Conservation Centre Dali UniversityDaliYunnan 671003China Guangdong Key Laboratory of Animal Conservation and Resource Utilization Institute of ZoologyGuangdong Academy of SciencesGuangzhouGuangdong 510663China School of Life Sciences Yunnan UniversityKunmingYunnan 650500China Key Laboratory of Southwest China Wildlife Resources Conservation(Ministry of Education) China West Normal UniversityNanchongSichuan 637001China Institute of International Rivers and Eco-security Yunnan UniversityKunmingYunnan 650500China School of Human Sciences The University of Western AustraliaPerthWA 6009Australia

The dual impact of climate change and human activities has precipitated a sharp decline in primate biodiversity *** is home to the most diverse primate species in the Northern hemisphere,which face severe ecological threats due to the expansion of modern agriculture,extensive exploitation and consumption of natural resources,and excessive land development during its transition from an agricultural to a modern *** response,China has implemented various ecological conservation measures,including habitat restoration and *** efforts have made substantial strides in biodiversity conservation,with certain regions witnessing an increase in primate *** the current study,we conducted a systematic review of historical documents and field research data related to Chinese primates,evaluating the endangered status of primate species in *** improvements in the habitats of most primate species and some population growth,many species still face severe threats,including declining and small *** such as the Myanmar snub-nosed monkey(Rhinopithecus strykeri),eastern black crested gibbon(Nomascus nasutus),and Hainan gibbon(***)remain particularly vulnerable due to their limited distribution ranges and extremely small *** scientific data,fragmented information,and not enough studies in conservation biology further compound the ***,there is a notable lack of detailed population monitoring data for species such as the Bengal slow loris(Nycticebus bengalensis),pygmy slow loris(***),Indochinese gray langur(Trachypithecus crepusculus),Shortridge’s langur(***),and capped langur(***),which hinders the development of practical and targeted conservation management ***,for national biodiversity conservation,there is an urgent need for specialized primate surveys,enhancing habitat protection and restoration,and increasing focus on cross-border conse

关键词： Primates Biodiversity Habitat fragmentation Habitat restoration Conservation strategies

Tumor heterogeneity and the potential role of liquid biopsy in bladder cancer

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Cancer Communications 2021年第2期41卷 91-108页

作者： Hai-ming huang Hai-xia Li Department of Clinical Laboratory Peking University First HospitalBeijing 100034P.R.China

Bladder cancer(BC)is a heterogeneous disease that characterized by genomic instability and a high mutation *** in tumor may partially explain the diversity of responses to targeted therapies and the various clinical outcomes.A combination of cytology and cystoscopy is the standard methodology for BC diagnosis,prognosis,and disease ***,genomics analyses of single tumor-biopsy specimens may underestimate the mutational burden of heterogeneous *** biopsy,as a promising technology,enables analysis of tumor components in the bodily fluids,such as blood and urine,at multiple time points and provides a minimally invasive approach that can track the evolutionary dynamics and monitor tumor *** this review,we describe the multiple faces of BC heterogeneity at the genomic and transcriptional levels and how they affect clinical care and *** also summarize the outcomes of liquid biopsy in BC,which plays a potential role in revealing tumor ***,we discuss the challenges that must be addressed before liquid biopsy can be widely used in clinical treatment.

关键词： bladder cancer genomic heterogeneity transcriptome heterogeneity liquid biopsy circulating tumor DNA

Bioengineered pseudovirus nanoparticles displaying the HA1 antigens of influenza viruses for enhanced immunogenicity

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Nano Research 2022年第5期15卷 4181-4190页

作者： ming xia Md Rejaul Hoq Pengwei huang Wen Jiang Xi Jiang ming Tan Division of Infectious Diseases Cincinnati Children’s Hospital Medical CenterCincinnatiOH 45229USA Department of Biological Sciences Purdue Cryo-EM FacilityPurdue UniversityIN 47907USA Department of Pediatrics University of Cincinnati College of MedicineCincinnatiOH 45229USA

Even with implementation of current influenza vaccines,influenza still claims up to 500,000 lives worldwide annually,indicating a need for a better vaccine *** have developed a technology to generate unique S_(60)-HA1 pseudovirus nanoparticles(PVNPs)that display the receptor-binding HA1 domains of influenza *** self-assembled S_(60)-HA1 PVNP consists of a T=1 icosahedral S_(60) nanoparticle that resembles the inner shell of norovirus capsid and 60 surface-displayed HA1 antigens that are excellent vaccine *** S_(60)-HA1 PVNPs presenting HA1 antigens of H7N9 influenza virus subtypes have been produced efficiently in large *** three-dimensional(3D)structures have been solved by cryogenic electron *** PVNP-displayed HA1 antigens react with HA-specific antibody,and retain authentic sialic acid binding specificity and hemagglutinate human *** PVNPs are highly immunogenic,eliciting high titers of HA1-specific antibodies in mice and the mouse sera strongly inhibited hemagglutinations of homologous and heterologous influenza virus HA ***,the S_(60)-HA1 PVNPs may provide useful reagents to study influenza viruses and offer a potential new vaccine tactic to fight the deadly influenza disease.

关键词： S_(60)nanoparticle pseudovirus nanoparticle influenza virus influenza vaccine hemagglutinin norovirus

基于多谱学技术剖析“白转黑”发用产品功效成分

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分析测试学报 2024年第7期43卷 971-977页

作者：夏泽敏梁文耀黄敏涵贾芳陈彦君孙剑聂明霞席绍峰谭建华广州质量监督检测研究院广州市NQI-质量安全科技协同创新中心广东广州511447

组合采用色谱、质谱、光谱及能谱等分析技术,对“白转黑”发用产品中可能存在的功效成分进行筛查、鉴定和确认。采用高效液相色谱靶向筛查常见染发剂,气相色谱-质谱联用和超高效液相色谱-高分辨质谱非靶向筛查可能存在的染发和致黑成分... 详细信息

组合采用色谱、质谱、光谱及能谱等分析技术,对“白转黑”发用产品中可能存在的功效成分进行筛查、鉴定和确认。采用高效液相色谱靶向筛查常见染发剂,气相色谱-质谱联用和超高效液相色谱-高分辨质谱非靶向筛查可能存在的染发和致黑成分。在优化的筛查条件下,超高效液相色谱-高分辨质谱识别出样品放置72 h后m/z 147.930 9处的峰强度出现明显下降。结合精准质量数、同位素分布及保留时间推测该成分为银离子。采用电感耦合等离子体质谱、离子色谱对银元素和硝酸根离子进行含量测定并结合原料性质剖析其来源,同时利用低真空热场发射扫描电镜对产品变黑成分进行确认,推测硝酸银可能是“白转黑”发用产品产生功效的重要原因。基于硝酸银为功效成分的“白转黑”发用产品在合规性和安全风险方面存在较大问题,亟需对该类产品加强监管。该文建立的组合式分析模式将为后续深入开展化妆品安全风险剖析提供技术参考。

关键词： “白转黑”发用产品多谱学技术功效成分安全风险

中成药治疗急性心肌梗死后心力衰竭的临床研究证据图分析

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中国中药杂志 2024年第6期49卷 1673-1682页

作者：张赤道黄金雨王永霞朱明军邢作英邱伯雍河南中医药大学河南郑州450000 河南中医药大学第一附属医院心脏中心河南郑州450000

通过证据图对中成药治疗急性心肌梗死后心力衰竭的临床研究进行全面梳理,了解该领域的证据分布。通过检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、中国生物医学文献服务系统(SinoMed)、PubMed、Cochrane Library、EMbase数据库,纳入... 详细信息

通过证据图对中成药治疗急性心肌梗死后心力衰竭的临床研究进行全面梳理,了解该领域的证据分布。通过检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、中国生物医学文献服务系统(SinoMed)、PubMed、Cochrane Library、EMbase数据库,纳入近20年中成药治疗急性心肌梗死后心力衰竭的随机对照试验(randomized controlled trial,RCT)、系统评价/Meta分析、指南/共识,以文字、图表、气泡图、柱状图相结合的形式对证据进行分析展示,分别采用RoB 1.0、AMSTAR2、AGREEⅡ对RCT、系统评价/Meta分析、指南/共识进行质量评价。共纳入163篇RCTs,4篇系统评价/Meta分析,1篇网状Meta分析,2篇观察性研究,5篇指南/共识。近年来,中成药治疗急性心肌梗死后心力衰竭发文量整体呈上升趋势,中成药种类较多,其中参附注射液的关注度最高。临床RCT和系统评价/Meta分析的文献质量普遍不高,RCT多为小样本、单中心、短周期;结局指标方面主要包括心功能指标、心肌损伤标志物、总有效率、血流动力学指标、安全性指标,中医特色疗效指标关注较少;部分指南/共识制定流程缺乏规范,导致其权威性和科学性有所降低。结果表明,中成药治疗急性心肌梗死后心力衰竭既有优势,但也存在问题,仍需更多高质量循证证据提供支撑,未来应开展更多大样本、多中心的临床试验,同时规范相关系统评价/Meta分析、指南/共识制定流程并提升其证据质量,以便进一步挖掘中成药治疗急性心肌梗死后心力衰竭的有效性和安全性。

关键词：中成药心肌梗死心力衰竭随机对照试验证据图系统评价

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