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Fabrication and biocompatible characterization of magnetic hollow capsules

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Chinese Chemical Letters 2008年第7期19卷 877-880页

作者： Hong Zhang Xing Long Gong Ling Yun Hao wan quan jiang Department of Chemistry Fuyang Normal College Fuyang 236041 China CAS Key Laboratory of Mechanical Behavior and Design of Materials University of Science and Technology of China Hefei 230026 China

Monodispersed Fe3O4/polypyrrole （PPy） hollow particles were synthesized via controllable in-situ deposition and polymerization techniques using poly（styrene-co-acrylic）（PSA） latex as template. Field-dependent magnetization plot illustrates that the capsules are superparamagnetic at 300 K. FTIR spectrum confirms that the myoglobin （Mb） molecule adsorbed on the surface of Fe3O4/PPy hollow particle essentially retains its native structure. Furthermore, direct electrochemistry of Mb can be realized on Fe3O4/PPy capsules modified pyrolytic graphite disk electrode, which indicates that the magnetic conductive polymer capsules can promote the electron transfer of protein.

关键词： Composite capsules Magnetic Biocompatibility

Radiation Vulcanization of Magnetorheological Elastomers Based on Silicone Rubber

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Chinese Journal of Chemical Physics 2009年第5期22卷 535-540,I0002页

作者： Wei Zhanga Xing-long Gong Jian-feng Li Hong Zhu wan-quan jiang CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern Mechanics University of Science and Technology of China Hefei 230027 China Department of Chemistry University of Science and Technology of China Hefei 230026 China

The fabrication of magnetorheological （MR） elastomers was studied by two vulcanization methods, including heat vulcanization （HV） and radiation vulcanization （RV）, were employed to fabricate MRE samples. The dynamical mechanical properties were characterized by using a dynamic mechanic analyzer. In particular, both the MR effect and its durability were investigated. The experimental results showed that RV samples have large magnetoinduced modulus, large zero-field modulus, and good durability property of MR effect. To explain these results, cubic deformation and plasticizer migration were analyzed. Large magneto-induced modulus of RV sample results from cubic deformation during vulcanization process. And the plasticizer migration results in better durability of MR effect.

关键词： Magnetorheological elastomer Radiation vulcanization Heat vulcanization

Research on the cyclostationary nearfield acoustic holography based on boundary element method

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Chinese Journal of Acoustics 2009年第1期28卷 87-96页

作者： ZHANG Haibin wan quan jiang Weikang State Key Laboratory of Mechanical System and Vibration Shanghai Jiaotong University Shanghai 200240

Cyclostationary sound field is a special kind of nonstationary sound field, in which the pressure signal is modulated seriously and sidebands exist in its spectrum. The reconstructed sound field can＇t figure the cyclostationary features in conventional Nearfield Acoustic Holography （NAH） procedure. On the basis of planar cyclostationary NAH, the cyclostationary NAH based on boundary element method is proposed which can be utilized to analyze radiators with complicated surface. Replacing the Fourier＇s transform with the second-order cyclic statistics, the Cyclic Spectral Density （CSD） functions is used as the reconstructed physical quantity in the proposed NAH technique, instead of the spectrum or power spectral density of pressure signal. By virtue of the demodulation ability of CSD function, the reconstructed CSD can effectively express the information of modulating and carrier wave respectively. The simulation and experiment illustrate that the validity and accuracy of this cyclostationary NAH technique satisfy the request of engineering.

关键词： Research on the cyclostationary nearfield acoustic holography based on boundary element method

The research about the multi-freedom degree reciprocity principle for diffuse sound field based on the sound pressure field description

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Chinese Journal of Acoustics 2010年第3期29卷 242-256页

作者： wan quan ZHANG Haibin jiang Weikang State Key Laboratory of Mechanical System and Vibration Shanghai Jiaotong University Shanghai 200240

The multi-DOF（degree-of-freedom） reciprocity principle for diffuse field was proposed and applied in the mid-frequency analysis of a complex vibro-acoustic *** the application of this diffuse reciprocity principle in a sound field leads the model to be unnecessarily enormous,one multi-DOF acoustic reciprocity principle more applicable for diffuse sound field is proposed ***,the＂blocked＂model of diffuse sound field is proposed to describe the blocked sound pressure on the surface of a structure excited by a diffuse sound field via sound radiation ***,the multi-DOF reciprocity principle for diffuse sound field based on the sound pressure description is proposed,which shows that the cross-spectrum matrix of the blocked sound pressure on the surface of a structure in a diffuse sound field is directly proportional to the real part of the acoustic impedance matrix of free field sound *** shows that the reciprocity principle is the similar form with the traditional single-DOF one,but applicable for the structure with arbitrary degrees of *** shows that this reciprocity principle can be applied in the auto-spectrum and the correlation analysis of the blocked sound pressure on the surface of an arbitrary shaped structure in a diffuse sound *** simulations show that the numerical results are consistent with the theoretical ones provide that the mesh size of boundary elements is smaller than one-sixth（linear element） or one-third （quadratic element） of the acoustic wavelength.

关键词： The research about the multi-freedom degree reciprocity principle for diffuse sound field based on the sound pressure field description mode

基于合并效率法对江都第三抽水站正反出流分析

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江苏水利 2017年第1期33卷 27-31页

作者：王骏秋万泉王江江苏省江都水利工程管理处江苏扬州225200

江都第三抽水站是南水北调东线源头4座大型泵站中唯一装有可逆式机组的水工建筑物,针对本站多种工况下的出流特性,根据工程更新改造后多年水文实测资料,采用合并效率法,计算推求出10台机组正转、反转下的效率系数,在数据精确度得到验证... 详细信息

江都第三抽水站是南水北调东线源头4座大型泵站中唯一装有可逆式机组的水工建筑物,针对本站多种工况下的出流特性,根据工程更新改造后多年水文实测资料,采用合并效率法,计算推求出10台机组正转、反转下的效率系数,在数据精确度得到验证后,对多种工程运行状态下合并效率曲线加以对比和分析,总结出水工建筑物的出流规律,力求为水利建设和地方经济的发展带来更大的工程效益。

关键词：泵站效率流量工况

Positive effect of Mo on mechanical properties of a Ni-42W-10Co-x Mo medium heavy alloy

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China Foundry 2025年

作者： Guo-xin Cao Jian-xin Dong Yong-sheng He He jiang Fang Hao Zhi-hua Nie Teng-fei Ma Bao-quan Fu School of Materials Science and Engineering University of Science and Technology Beijing Xi'an Superalloy Technology Co. Ltd. School of Materials Science and Engineering Beijing Institute of Technology Key Laboratory of Air-driven Equipment Technology of Zhejiang Province Quzhou University

In this study,a novel Ni-W-Co-Mo medium heavy alloy (MHA) was designed to improve its mechanical strength via Mo *** the Ni-42W-10Co-xM o alloy series,where x represents the weight percent of Mo and varies between 0,1,2,5,and 10,the microstructure transitions from a dendritic structure to a hypoeutectic structure as the Mo content increases from 0 to 5wt.%.Moreover,as the Mo content increases from 0to 10wt.%,the distribution of theμ-phase shifts from being individually dispersed to forming aggregates,and its volume fraction rises from 0.5%to 7.9%.Notably,theμ-phase evolves into an eutectic microstructure,which helps in minimizing the segregation of *** change is accompanied by a substantial enhancement in mechanical properties;specifically,the compressive yield strength at room temperature increases from 350 MPa to 646 MPa,indicating a significant 85%***,the microhardness increases from 230 HV to 304 *** dynamics simulations further reveal that the strengthening mechanism of Ni-42W-10Co-xM o alloys is Mo-induced solid solution strengthening and precipitation strengthening.

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Unraveling the mechanism of action of Shangxia Liangji formula for treating insomnia:a metabolomics and network pharmacology approach

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Traditional Medicine Research 2025年第2期10卷 16-29页

作者： Xia-Jie quan Hao Liang Yong-Hong Tang Li jiang Xiong-Ying Ji Feng-Ying Zhang Ping Zhang Bo Ouyang Department of Information The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Neurology The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Gastroscopy The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Traditional Chinese Medicine The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China

Background:Insomnia is a prevalent clinical condition and Shangxia Liangji formula(SXLJF)is a well-established method of ***,the specific mechanism of action of SXLJF remains ***:The mouse model of insomnia was established by intraperitoneal injection of ***-two mice were randomly divided into a negative control group,model group,SXLJF group(18.72 g/kg/day),and positive control group(diazepam,2 mg/kg)and treated with the corresponding drugs for 7 consecutive *** open field test and pentobarbital-induced sleeping test were ***-MS-based untargeted metabolomics and network pharmacology were applied to explore the potential targets of SXLJF for treating ***,key targets were validated using ***:Behavioral tests demonstrated that SXLJF reduced the total distance,average velocity,central distance,and sleep latency,and prolonged sleep *** and network pharmacology revealed potential targets,signaling pathways,metabolic pathways,and metabolites associated with the anti-insomnia effects of ***,tyrosine hydroxylase(TH)and tyrosine metabolism emerged as crucial metabolic pathways and targets,***-qPCR results supported the role of TH in the mechanism of SXLJF in treating ***:In conclusion,TH and tyrosine metabolism may represent significant targets and pathways for SXLJF in treating insomnia.

关键词： Shangxia Liangji formula insomnia metabolomics network pharmacology tyrosine hydroxylase tyrosine metabolism

Mechanism of action of Linggui Zhugan Decoction in treating non-alcoholic fatty liver disease using untargeted metabolomics approach

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Traditional Medicine Research 2025年第2期10卷 65-76页

作者： Huan Pei Ren-Lin Li Xin-Ran Song Qian-Qian wan Yu-Ming wang Han-Zhou Li Wei-quan Xu Jia-Bao Liao Wei-Bo Wen Jing Miao Huan-Tian Cui School of Basic Medicine Yunnan University of Chinese MedicineKunming 650599China School Clinical Medical College Yunnan University of Chinese MedicineKunming 650599China First School of Clinical Medicine Yunnan University of Chinese MedicineKunming 650599China School of Integrative Chinese and Western Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China Department of Pharmacy Tianjin Second People's HospitalTianjin 300192China

Background:Non-alcoholic fatty liver disease(NAFLD)is a liver disorder characterized by the accumulation and degeneration of fat in the liver cells,a condition that may further deteriorate and lead to cirrhosis and liver *** studies showed that metabolic dysfunction can promote NAFLD *** Zhugan Decoction(LGZGD)has therapeutic effects on *** mechanism of LGZGD still remains *** study was to examine the impact of LGZGD on the metabolic processes involved in the development of ***:A mice model of NAFLD was treated with *** therapeutic potential of LGZGD was evaluated by assessing the activity of transaminases,lipids levels of blood,and pathological changes in the liver of the mice model of ***,this study also evaluated the influence of LGZGD on liver inflammation and oxidative ***:The results of untargeted metabolomics analysis showed that LGZGD reduced the disordered lipid metabolism in NAFLD *** improved the oxidative stress and also reduced the levels of pro-inflammatory cytokines in the *** metabolomics analysis of liver samples revealed that LGZGD treatment improved metabolic disorders,including alanine,aspartate,glutamate,glycerophospholipid metabolism,and citrate *** RT-qPCR and Western blot results showed that LGZGD could regulate the expression of key enzymes in the metabolic pathway of the citrate cycle,including ATP-citrate lyase(ACLY),alanine-glyoxylate aminotransferase-2(AGXT2),phosphatidylethanolamine N-methyltransferase(PEMT),and succinate dehydrogenase(SDH).Conclusion:We found that LGZGD can treat NAFLD by reducing inflammatory responses,inhibiting oxidative stress,regulating alanine,aspartate,glutamate,and glycerophospholipid metabolism,and citrate cycle pathways.

关键词： NAFLD LGZGD untargeted metabolomics glycerophospholipid metabolism citrate cycle

Transient Response in a Bi-material Cylinder of Soft Ferromagnetic Material Subjected to Magnetic Shock

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Acta Mechanica Solida Sinica 2021年第2期34卷 286-296页

作者： Zhangjianing Cheng quan jiang College of Civil Engineering Tongji UniversityShanghai 200092China School of Transportation and Civil EngiTieering Nantong UniveirsityNantong 226019China

The transient response in a bi-material cylinder of soft ferromagnetic material under magnetic shock is investigated in this *** analytical solutions for displacement and stress have been derived using the finite Hankel transform and the Laplace *** numerical examples show that the displacement and stress fields respond dynamically in the bi-material cylinder under magnetic *** derived displacement at the center and radial stress on the surface of the cylinder satisfy the boundary conditions,showing the correctness of *** displacement and stress waves propagate from the surface to the center of the cylinder when the magnetic field is *** stress fields increase from the center to the surface of the cylinder and are much larger than the quasi-static state since the waves reflect,collide and concentrate in the body of the *** method of this paper can be used in the design of soft ferromagnetic structures.

关键词： Soft ferromagnetic material Bi-material cylinder Transient stress Magnetic shock