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Lanthanide-based microlasers:Synthesis,structures,and biomedical applications

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Nano Research 2024年第1期17卷 97-111页

作者： qian zhang Yawei Liu Kai Liu Hongjie zhang Engineering Research Center of Advanced Rare Earth Materials(Ministry of Education) Department of ChemistryTsinghua UniversityBeijing 100084China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China Xiangfu Laboratory Jiaxing 314102China

The large size of lasers limits their applications in confined spaces,such as in biosensing and in vivo brain tissue *** this regard,micron-sized lasers have been *** exhibit great potential for biological detecting,remote sensing,and depth tracking due to their small sizes,sensitive properties of their spectral fingerprints,and flexible positional modulation in the ***-based luminescent materials that possess long excited-state lifetime,narrow emission bandwidth,and upconversion behaviors are promising as gain mediums for novel *** addition,lanthanide-based microlasers could be generated under natural ambient conditions with pumped or continuous light sources,which significantly promotes the practical applications of *** progress in the design,synthesis,and biomedical applications of lanthanide-based microlasers has been outlined in this *** ions doped and upconverted lanthanide-based microlasers are highlighted,which exhibit advantageous structures,miniaturized dimensions,and high lasing *** applications of lanthanide-based microlasers are further discussed,the upconverted microlasers show great advantages for biological applications owing to their tunable excitation and emission characteristics and excellent environmental ***,perspectives and challenges in the field of lanthanide-based microlasers are presented.

关键词： microlasers lanthanide-based luminescent materials upconversion nanoparticles biological applications

Existence and asymptotics of normalized solutions for the logarithmic Schrödinger system

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Science China Mathematics 2024年第9期67卷 2019-2048页

作者： qian zhang Wenming Zou Department of Mathematical Sciences Tsinghua UniversityBeijing 100084China

This paper is concerned with the following logarithmic Schrodinger system:{-Δu_(1)+ω_(1)u_(1)=u_(1)u_(1)logu_(1)^(2)+2p/p+q|u_(2)|^(q)|u_(1)|^(p-2)u_(1),-Δu_(2)+ω_(2)u_(2)=u_(2)u_(2)log u_(2)^(2)+2q/p+q|u_(1)|^(p)|u_(2)|^(q-2)u_(2),∫_(Ω)|u_(i)|^(2)dx=ρ_(i),i=1,2,(u_(1),u_(2))∈H_(0)^(1)(Ω;R^(2)),where Ω=R^(N)or Ω■R^(N)(N≥3)is a bounded smooth domain,andω_(i)R,μ_(i),ρ_(i)>0 for i=1,***,p,q≥1,and 2≤p+q≤2^(*),where 2^(*):=2N/*** using a Gagliardo-Nirenberg inequality and a careful estimation of u log u^(2),firstly,we provide a unified proof of the existence of the normalized ground state solution for all 2≤p+q≤2^(*).Secondly,we consider the stability of normalized ground state ***,we analyze the behavior of solutions for the Sobolev-subcritical case and pass to the limit as the exponent p+q approaches 2^(*).Notably,the uncertainty of the sign of u log u^(2)in(0,+∞)is one of the difficulties of this paper,and also one of the motivations we are interested *** particular,we can establish the existence of positive normalized ground state solutions for the Brézis-Nirenberg type problem with logarithmic perturbations(i.e.,p+q=2^(*)).In addition,our study includes proving the existence of solutions to the logarithmic type Bréis-Nirenberg problem with and without the L^(2)-*** ∫_(Ω)|u_(i)|^(2)dx=ρ_(i)(i=1,2)by two different methods,*** results seem to be the first result of the normalized solution of the coupled nonlinear Schrodinger system with logarithmic perturbations.

关键词： logarithmic Schrodinger system Brézis-Nirenberg problem normalized solution existence and stability behavior of solutions

Learning physically based material and lighting decompositions for face editing

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Computational Visual Media 2024年第2期10卷 295-308页

作者： qian zhang Vikas Thamizharasan James Tompkin Brown University ProvidenceRhode Island 02906USA

Lighting is crucial for portrait photography,yet the complex interactions between the skin and incident light are expensive to model computationally in graphics and difficult to reconstruct analytically via computer ***,to allow fast and controllable reflectance and lighting editing,we developed a physically based decomposition through deep learned priors from path-traced portrait *** approaches that used simplified material models or low-frequency or low-dynamic-range lighting struggled to model specular reflections or relight directly without intermediate ***,we estimate the surface normal,skin albedo and roughness,and high-frequency HDRI maps,and propose an architecture to estimate both diffuse and specular reflectance *** our experiments,we show that this approach can represent the true appearance function more effectively than simpler baseline methods,leading to better generalization and higher-quality editing.

关键词： intrinsic decomposition portrait relighting inverse rendering deep learning

Performance evaluation of HY-2 series satellites in marine gravity field recovery

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Geodesy and Geodynamics 2024年第4期15卷 397-403页

作者： Ruijie Hao Xiaoyun wan Keyan zhang School of Land Science and Technology China University of Geosciences(Beijing)Beijing100083China School of Geospatial Engineering and Science Sun Yat-Sen UniversityZhuhai519082China

China has successfully launched four Haiyang-2(HY-2)series altimetry ***-2A has attracted significant attention in gravity field recovery,but the performance of other HY-2 series satellites,including HY-2B/C/D,is seldom *** study evaluated the performance of all the HY-2 series satellites in recovering marine gravity ***,the crossover discrepancies in sea surface height of the four satellites,HY-2A,HY-2B,HY-2C,and HY-2D,were analyzed to assess their altimetry *** was found that HY-2B had the best altimetry quality,followed by ***,different combina-tions of altimetry data were used to calculate vertical deflections and gravity anomalies in the South China Sea(112°E-119°E,12°N-20°N).The results showed that combining data from HY-2B,HY-2C,and HY-2D improved the inversion accuracy of gravity anomalies by 0.3 mGal compared to using HY-2A data ***-2C and HY-2D contributed to enhancing the accuracy of the east component of vertical deflections.

关键词： Satellite altimetry HY-2 Sea surfaceheight Marinegravityfield

STAT3 ameliorates truncated tau-induced cognitive deficits

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Neural Regeneration Research 2024年第4期19卷 915-922页

作者： Bingge zhang Huali wan Maimaitijiang Maierwufu qian Liu Ting Li Ye He Xin wang Gongping Liu Xiaoyue Hong Qiong Feng Department of Pathophysiology School of Basic Medicine and the Collaborative Innovation Center for Brain ScienceKey Laboratory of Ministry of Education of China and Hubei Province for Neurological DisordersTongji Medical CollegeHuazhong University of Science and Technology Department of Laboratory Medicine Guangdong ProvincialPeople's Hospital(Guangdong Academy of Medical Sciences)Southern Medical University Department of Laboratory Medicine Zhongnan Hospital of Wuhan University Department of Pathology Wuhan Children's HospitalTongji Medical CollegeHuazhong University of Science and Technology

Proteolytic cleavage of tau by asparagine endopeptidase(AEP)creates tau-N368 fragments,which may drive the pathophysiology associated with synaptic dysfunction and memory deterioration in the brain of Alzheimer’s disease ***,the molecular mechanisms of truncated tau-induced cognitive deficits remain *** suggests that signal transduction and activator of transcription-3(STAT3)is associated with modulating synaptic plasticity,cell apoptosis,and cognitive *** luciferase reporter assays,electrophoretic mobility shift assays,western blotting,and immunofluorescence,we found that human tau-N368 accumulation inhibited STAT3 activity by suppressing STAT3 translocation into the *** of STAT3 improved tau-N368-induced synaptic deficits and reduced neuronal loss,thereby improving the cognitive deficits in tau-N368 ***,in tau-N368 mice,activation of STAT3 increased N-methyl-D-aspartic acid receptor levels,decreased Bcl-2 levels,reversed synaptic damage and neuronal loss,and thereby alleviated cognitive deficits caused by *** together,STAT3 plays a critical role in truncated tau-related neuropathological *** indicates a new mechanism behind the effect of tau-N368 on synapses and memory ***3 can be used as a new molecular target to treat tau-N368-induced protein pathology.

关键词： Alzheimer’s disease apoptosis cognitive deficit memory neurodegenerative disease neuron loss N-methyl-D-aspartic acid receptor STAT3 synapse tau-N368

Hybrid Dynamic Variables-Dependent Event-Triggered Fuzzy Model Predictive Control

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IEEE/CAA Journal of Automatica Sinica 2024年第3期11卷 723-733页

作者： Xiongbo wan Chaoling zhang Fan Wei Chuan-Ke zhang Min Wu IEEE the School of Automation China University of Geosciencesthe Hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex Systemsand the Engineering Research Center of Intelligent Technology for Geo-ExplorationMinistry of EducationWuhan 430074China

This article focuses on dynamic event-triggered mechanism(DETM)-based model predictive control(MPC) for T-S fuzzy systems.A hybrid dynamic variables-dependent DETM is carefully devised,which includes a multiplicative dynamic variable and an additive dynamic *** addressed DETM-based fuzzy MPC issue is described as a “min-max” optimization problem(OP).To facilitate the co-design of the MPC controller and the weighting matrix of the DETM,an auxiliary OP is proposed based on a new Lyapunov function and a new robust positive invariant(RPI) set that contain the membership functions and the hybrid dynamic variables.A dynamic event-triggered fuzzy MPC algorithm is developed accordingly,whose recursive feasibility is analysed by employing the RPI *** the designed controller,the involved fuzzy system is ensured to be asymptotically *** examples show that the new DETM and DETM-based MPC algorithm have the advantages of reducing resource consumption while yielding the anticipated performance.

关键词： Dynamic event-triggered mechanism(DETM) hybrid dynamic variables model predictive control(MPC) robust positive invariant(RPI)set T-S fuzzy systems

Characteristics and distribution of microstructures in high pressure die cast alloys with X-ray microtomography:A review

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China Foundry 2024年第5期21卷 427-444页

作者： Hai-dong Zhao Xue-ling wang qian wan Wen-hui Bai Fei Liu School of Mechanical and Automotive Engineering South China University of TechnologyGuangzhou 510640China

Al and Mg alloy high pressure die castings(HPDC)are increasingly used in automotive *** microstructures in the castings have decisive effect on the casting mechanical properties,in which the microstructure characteristics are fundamental for the investigation of the microstructure-property *** the past decade,the microstructure characteristics of HPDC Al and Mg alloys,especially micro-pores andα-Fe,have been investigated from two-dimensional(2D)to threedimensional with X-ray micro-computed tomography(μ-CT).This paper provides an overview of the current understanding regarding the 3D characteristics and formation mechanisms of microstructures in HPDC alloys,their spatial distributions,and the impact on mechanical ***,it outlines future research directions for the formation and control of heterogeneous microstructures in HPDC alloys.

关键词： high pressure die casting microstructure three-dimensional characteristics distribution Al and Mg alloys

A Spleen Tyrosine Kinase’s Sky in Neuronal Degeneration

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Neuroscience Bulletin 2024年第2期40卷 273-276页

作者： wan-Yun zhang Sen Lin Department of Neurology Xinqiao HospitalThe Second Afliated HospitalArmy Medical UniversityChongqing 400042China Chongqing Institute for Brain and Intelligence Guangyang Bay LaboratoryChongqing 400064China

With the growing elderly population,neurodegenerative disorders like Alzheimer's disease(AD)are emerging as a significant public health *** is widely acknowledged in the scientific community that the accumulation of neurotoxic aggregates,such as amyloid beta(Aβ),within the central nervous system is a major factor in the development of these ***,human genome-wide association studies have identified mutations in microglial receptors that may be linked to a number of neurodegenerative diseases[1].

关键词： Aβ Spleen Alzheimer

Global patterns and ecological drivers of taxonomic and phylogenetic endemism in angiosperm genera

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Plant Diversity 2024年第2期46卷 149-157页

作者： Hong qian Brent D.Mishler Jian zhang Shenhua qian Research and Collections Center Illinois State Museum1011 East Ash StreetSpringfieldIL 62703USA University and Jepson Herbaria Department of Integrative BiologyUniversity of CaliforniaBerkeleyCA 94720-2465USA Center for Global Change and Complex Ecosystems Zhejiang Tiantong Forest Ecosystem National Observation and Research StationSchool of Ecological and Environmental SciencesEast China Normal UniversityShanghai 200241China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092China Key Laboratory of the Three Gorges Reservoir Region's Eco-Environment Ministry of EducationChongqing UniversityChongqing 400045China

Endemism of lineages lies at the core of understanding variation in community composition among geographic regions because it reflects how speciation,extinction,and dispersal have influenced current ***,we investigated geographic patterns and ecological drivers of taxonomic and phylogenetic endemism of angiosperm genera across the *** identify centers of paleo-endemism and neo-endemism of angiosperm genera,and show that they are mostly located in the Southern Hemisphere in tropical and subtropical regions,particularly in Asia and *** categories of phylogenetic endemism centers can be differentiated using current climate *** climate,historical climate change,and geographic variables together explained~80%of global variation in taxonomic and phylogenetic endemism,while 42-46%,1%,and 15%were independently explained by these three types of variables,*** our findings show that past climate change,current climate,and geography act together in shaping endemism,which are consistent with the findings of previous studies that higher temperature and topographic heterogeneity promote *** study showed that many centers of phylogenetic endemism of angiosperms,including regions in Amazonia,Venezuela,and west-central tropical Africa that have not previously been identified as biodiversity hotspots,are missed by taxon-based measures of endemism,indicating the importance of including evolutionary history in biodiversity assessment.

关键词： Angiosperm Current climate Endemism Historical climate change Topographic heterogeneity