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An Integral Method for Solving Dynamic Equations with Fluid–Solid Coupling

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Acta Mechanica Solida Sinica 2024年第1期37卷 99-108页

作者： Xin Zhang Jie Liu pu Xue Shuowen yan Yahao Xu M.S.Zahran School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China School of Mechatronical Engineering Beijing Institute of TechnologyBeijing 100081China Department of Civil Engineering Military Technical CollegeCairo 11435Egypt

In this work,a new methodology is presented to mainly solve the fluid–solid interaction(FSI)*** methodology combines the advantages of the Newmark precise integral method(NPIM)and the dual neural network(DNN)*** NPIM is employed to modify the exponential matrix and loading vector based on the DNN integral *** involves incorporating the basic assumption of the Newmark-βmethod into the dynamic equation and eliminating the acceleration term from the dynamic equilibrium *** a result,the equation is reduced to a first-order linear equation ***,the PIM is applied to integrate the system step by step within the *** DNN method is adopted to solve the inhomogeneous term through fitting the integrand and the original function with a pair of neural networks,and the integral term is solved using the Newton–Leibniz *** examples demonstrate that the proposed methodology significantly improves computing efficiency and provides sufficient precision compared to the DNN *** is particularly evident when analyzing large-scale structures under blast loading conditions.

关键词： Newmark precise integral method(NPIM) Dual neural networks(DNN) Fluid-solid interaction(FSI) Dynamic time-history analysis Blast loading

Significant enhancement in local thermal conductivity of erythritol at interface with nanoparticles due to their interaction

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Nano Research 2024年第8期17卷 7726-7736页

作者： Ning Cao yanhui Feng Kening yan Zihan Liu Jiawei wan Lin Qiu School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Biochemical Engineering Key Laboratory of Biopharmaceutical Preparation and DeliveryInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China

When nano-fillers are used to enhance the thermal conductivity of organic phase change materials(PCMs),the naturally formed interface is considered to hinder thermal transport of the composite ***,the effect of the interface on the thermal properties of surrounding PCM has not been fully *** this paper,three composite PCMs(Ery@SiC,Ery@SiO_(2) and Ery@Si_(3)N_(4))were prepared by melt-blending *** local thermal conductivity and reduced Young’s modulus(E^(*))of the erythritol at the interface and far away from the interface in the composite PCMs were simultaneously measured by scanning thermal microscopy(SThM).The results revealed significant enhancement in local thermal conductivity of erythritol at the interface and its obvious positive correlation with E^(*).For different composite PCMs,molecular dynamics(MD)simulations suggested that the increase in intrinsic thermal conductivity and E^(*)of erythritol is attributed to the increase in interaction energy between erythritol and nanoparticles,as more erythritol phonon vibrations transform from localized mode to delocalized mode and erythritol has a higher density at the *** findings will provide new ideas for the design of PCM for energy storage.

关键词： scanning thermal microscopy phase change materials thermal conductivity reduced Young’s modulus interaction energy phonon participation ratio

Magnetic Fields Reduce Apoptosis by Suppressing Phase Separation of Tau-441

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Research 2024年第1期2023卷 181-197页

作者： Wen-Juan Lin Wen-pu Shi wan-Yi Ge Liang-Liang Chen Wei-Hong Guo Peng Shang Da-Chuan Yin Key Laboratory for Space Bioscience and Biotechnology School of Life SciencesNorthwestern Polytechnical University127 Youyixi RoadXi'an 710072ShaanxiPR China

The biological effects of magnetic fields(MFs)have been a controversial ***,in recent years,there has been increasing evidence that MFs do affect biological ***,the physical mechanism remains ***,we show that MFs(16 T)reduce apoptosis in cell lines by inhibiting liquid–liquid phase separation(LLPS)of Tau-441,suggesting that the MF effect on LLPS may be one of the mechanisms for understanding the“mysterious”magnetobiological *** LLPS of Tau-441 occurred in the cytoplasm after induction with *** phase-separated droplets of Tau-441 recruited hexokinase(HK),resulting in a decrease in the amount of free HK in the *** cells,HK and Bax compete to bind to the voltage-dependent anion channel(VDAC I)on the mitochondrial membrane.A decrease in the number of free HK molecules increased the chance of Bax binding to VDAC I,leading to increased Bax-mediated *** the presence of a static MF,LLPS was marked inhibited and HK recruitment was reduced,resulting in an increased probability of HK binding to VDAC I and a decreased probability of Bax binding to VDAC I,thus reducing Bax-mediated *** findings revealed a new physical mechanism for understanding magnetobiological effects from the perspective of *** addition,these results show the potential applications of physical environments,such as MFs in this study,in the treatment of LLPS-related diseases.

关键词： inhibited Apoptosis finding

Stable carbon isotope composition and intrinsic water use efficiency in plants along an altitudinal gradient on the eastern slope of Yulong Snow Mountain, China

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Ecological Processes 2024年第2期13卷 218-230页

作者： Feng Jiang Tao pu Zi-Jing Xue yan-Wei Ma Xiao-Yi Shi Fu-Xi Shi College of Geography and Environmental Sciences Zhejiang Normal University Yulong Snow Mountain Glacier and Environment Observation and Research Station/State Key Laboratory of Cryospheric Sciences Northwest Institute of Eco-Environment and ResourcesChinese Academy of Sciences Key Laboratory of National Forestry and Grassland Administration on Forest Ecosystem Protection and Restoration of Poyang Lake Watershed College of Forestry Jiangxi Agricultural University

Background Stable carbon isotope composition(δ13Cp) can be used to estimate the changes in intrinsic water use efficiency（iWUE） in plants,which helps us to better understand plants' response strategies to climate *** study focused on the variations in δ13Cpand iWUE for the different life-form plants（i.e.,herbs,shrubs,and trees）along an altitudinal gradient（3300,3600,3900,4100,4300,and 4500 m） on the eastern slope of Yulong Snow Mountain,southeastern margin of the Qinghai-Tibet *** response mechanisms of δ13Cpand iWUE for different life-form plants to altitude were thoroughly analyzed in this mountain *** The δ13Cpvalues of plants on the eastern slopes of Yulong Snow Mountain ranged from-30.4‰to-26.55‰,with a mean of-28.02‰,indicating a dominance of *** δ13Cpand iWUE values varied among different life-form plants in the order of herbs> shrubs> trees,particularly in 3600,3900,and 4300 ***δ13Cpand iWUE values for herbs and shrubs increased with altitude and were mainly controlled by air *** two parameters for trees exhibited a trend of initial decrease followed by an increase with *** 3900 m,the δ13Cpand iWUE values decreased with altitude,influenced by soil ***,above 3900 m,the two parameters increased with altitude,mainly regulated by air *** addition,iWUE was positively correlated with leaf P content but negatively correlated with leaf N:P ratio,especially for herbs and trees,suggesting that P plays a key role in modulating iWUE in this *** The diffe rentiated responses of water availability for different life-form plants to a higher altitudinal gradient are regulated by air temperature,soil moisture,and leaf P content in the Yulong Snow *** results provide valuable insights into understanding the wate r-carbon relationships in high-altitude ecosystems.

关键词： Stable carbon isotope Water use efficiency Altitude Life form Yulong Snow Mountain

Efficient stochastic parallel gradient descent training for on-chip optical processor

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Opto-Electronic Advances 2024年第4期7卷 5-15页

作者： Yuanjian wan Xudong Liu Guangze Wu Min yang Guofeng yan Yu Zhang Jian wang Wuhan National Laboratory for Optoelectronics and School of Optical and Electronic Information Huazhong University of Science and TechnologyWuhan 430074China Optics Valley Laboratory Wuhan 430074China

In recent years,space-division multiplexing(SDM)technology,which involves transmitting data information on multiple parallel channels for efficient capacity scaling,has been widely used in fiber and free-space optical communication *** enable flexible data management and cope with the mixing between different channels,the integrated reconfig-urable optical processor is used for optical switching and mitigating the channel ***,efficient online train-ing becomes intricate and challenging,particularly when dealing with a significant number of *** we use the stochastic parallel gradient descent(SPGD)algorithm to configure the integrated optical processor,which has less com-putation than the traditional gradient descent(GD)*** design and fabricate a 6×6 on-chip optical processor on silicon platform to implement optical switching and descrambling assisted by the online training with the SPDG ***,we apply the on-chip processor configured by the SPGD algorithm to optical communications for optical switching and efficiently mitigating the channel crosstalk in SDM *** comparison with the traditional GD al-gorithm,it is found that the SPGD algorithm features better performance especially when the scale of matrix is large,which means it has the potential to optimize large-scale optical matrix computation acceleration chips.

关键词： optical communications optical signal processing channel descrambling optical neural network chip silicon photonics

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Reliability of DC-link capacitor in pulsed power supply for accelerator magnet

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Nuclear Science and Techniques 2024年第9期35卷 28-40页

作者： Jie wang Da-Qing Gao wan-Zeng Shen Hong-Bin yan Li-Jun Mao Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China

Capacitors are widely used in pulsed magnet power supplies to reduce ripple voltage,store energy,and decrease power *** this study,DC-link capacitors in pulsed power supplies were *** deriving an analytical method for the capacitor current on the H-bridge topology side,the root-mean-square value of the capacitor current was calculated,which helps in selecting the DC-link *** proposed method solves this problem quickly and with high *** current reconstruction of the DC-link capacitor is proposed to avoid structural damage in the capacitor’s current measurement,and the capacitor’s hotspot temperature and temperature rise are calculated using the FFT *** test results showed that the error between the calculated and measured temperature increases was within 1.5℃.Finally,the lifetime of DC-link capacitors was predicted based on Monte Carlo *** proposed method can evaluate the reliability of DC-link capacitors in a non-isolated switching pulsed power supply for accelerators and is also applicable to film capacitors.

关键词： Aluminum electrolytic capacitor DC-link current DC–DC power converter Hotspot temperature

维普期刊数据库

Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer:final overall survival analysis of the EMERGING-CTONG 1103 randomised phase II trial

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Signal Transduction and Targeted Therapy 2023年第3期8卷 1310-1317页

作者： Wen-Zhao Zhong Hong-Hong yan Ke-Neng Chen Chun Chen Chun-Dong Gu Jun wang Xue-Ning yang Wei-Min Mao Qun wang Gui-Bin Qiao Ying Cheng Lin Xu Chang-Li wang Ming-Wei Chen Xiao-Zheng Kang wan-pu yan Ri-Qiang Liao Jin-Ji yang Xu-Chao Zhang Si-yang Liu Qing Zhou Yi-Long Wu Guangdong Provincial People’s Hospital Guangdong Academy of Medical Sciences510080 GuangzhouChina Peking University Cancer Hospital and Institute 100142 BeijingChina Fujian Medical University Union Hospital 350001 FuzhouChina First Affiliated Hospital of Dalian Medical University 116011 DalianChina Peking University People’s Hospital 100044 BeijingChina Zhejiang Cancer Hospital 310022 HangzhouChina Zhongshan Hospital 200032 ShanghaiChina Guangzhou Liuhuaqiao Hospital 510000 GuangzhouChina Jilin Provincial Tumor Hospital 130012 ChangchunChina Jiangsu Cancer Institute and Hospital 210009 NanjingChina Tianjin Medical University Cancer Institute and Hospital 300060 TianjinChina First Affiliated Hospital of Xi’an Jiaotong University 710061 Xi’anChina

EMERGING-CTONG 1103 showed improved progression-free survival(PFS)with neoadjuvant erlotinib *** for patients harbouring EGFR sensibility mutations and R0 resected stage IIIA-N2 non-small cell lung cancer(NSCLC)(NCT01407822).Herein,we report the final *** patients were randomly allocated 1:1 to the erlotinib group(150 mg/day orally;neoadjuvant phase for 42 days and adjuvant phase to 12 months)or to the GC group(gemcitabine 1250 mg/m2 plus cisplatin 75 mg/m2 intravenously;2 cycles in neoadjuvant phase and 2 cycles in adjuvant phase).Objective response rate(ORR),complete pathologic response(pCR),PFS,and overall survival(OS)were assessed along with *** hoc analysis was performed for subsequent treatments after disease *** investigated 72 patients(erlotinib,n=37;GC,n=35),the median follow-up was 62.5 *** median OS was 42.2 months(erlotinib)and 36.9 months(GC)(hazard ratio[HR],0.83;95%confidence interval[CI],0.47-1.47;p=0.513).The 3-and_(5-y)ear OS rates were 58.6%and 40.8%with erlotinib and 55.9%and 27.6%with GC(p_(3-y)=0.819,p_(5-y)=0.252).Subsequent treatment was administered in 71.9%and 81.8%of patients receiving erlotinib and GC,respectively;targeted therapy contributed mostly to OS(HR,0.35;95%CI,0.18-0.70).After disease progression,the ORR was 53.3%,and the median PFS was 10.9 months during the EGFR-TKI *** postoperative therapy,grade 3 or 4 adverse events(AEs)were 13.5%in the erlotinib group and 29.4%in the GC *** serious adverse events were *** exhibited clinical feasibility for resectable IIIA-N2 NSCLC over chemotherapy in the neoadjuvant setting.

关键词： neoadjuvant cisplatin chemotherapy

Enhanced fluorescence sensing of tetracycline with Ti_(2)C quantum dots

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Nano Research 2024年第4期17卷 3180-3188页

作者： Dejia Hu ShangZuo Jiang Tianhao Xia Danyang Xiao yan Li yanbing Hou Jin Zhong Zhang Ying-Chih pu School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China Key Lab Luminescence&Optical Information Ministry EducationBeijing JiaoTong UniversityBeijing 100044China Department of Chemistry and Biochemistry University of CaliforniaSanta CruzCalifornia 95064USA Department of Materials Science "National University of Tainan"Tainan 700301TaiwanChina

Ti_(2)C quantum dots(QDs)with rich surface functional groups have been synthesized using a hydrothermal method,and used to detect tetracycline(Tc)based on enhanced *** interaction between the surface functional groups of Ti_(2)C QDs and Tc enhanced the fluorescence of Tc at 514 nm,which is used to detect Tc quickly and *** optimal conditions,the fluorescence intensity was linear to the concentration of Tc in the range of 50.0–30.0μM,with a detection limit of 21.6 ***,the Tc-Ti_(2)C QDs detection system was evaluated for detection of Tc in milk and artificial *** study demonstrates a new and simple strategy for Tc detection,which is important for food safety and human health.

关键词： Ti_(2)C MXene quantum dots tetracycline fluorescence enhancement detection

Modulated symbol-based one-time pad secure transmission scheme using physical layer keys

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Science China(Information Sciences) 2024年第1期67卷 221-239页

作者： Xiaoyan HU Zheng wan Kaizhi HUANG Liang JIN Mengyao yan Yajun CHEN Jinmei yanG Information Engineering University purple Mountain Laboratories for Network and Communication Security

This paper proposes a novel modulated symbols-based one-time pad(SOTP) secure transmission scheme using physical layer *** classical physical layer key generation and exclusive OR(XOR)encryption in the discrete binary space,we design a framework for modulated symbols-based one-time pad(OTP) encryption,where the cryptographic primitive and mathematical model of SOTP is given to build a practical cryptographic *** with existing physical layer encryption(PLE) schemes,we provide rigorous proof that the framework can meet perfect secrecy and correctness *** addition,we provide a specific scheme of physical layer OTP secure transmission for quadrature amplitude modulation(QAM) and phase-shift keying(PSK) symbols based on physical layer *** scheme realizes the unification of bit encryption and symbol encryption,which can adaptively select the quantization level according to the signal-to-noise ratio(SNR) to minimize the symbol error rate(SER).Further,we analyze the performance quantitatively and derive the closed-form expressions of SER,which indicates that the proposed scheme has a lower ***,simulation results verify that the proposed symbol-wise OTP secure transmission scheme can achieve perfect secrecy and high reliability.

关键词： physical layer security one-time pad wireless channel physical layer encryption perfect secrecy