检索结果-南通市图书馆

Neural-like cells from adipose-derived stem cells for cavernous nerve injury in rats

Neural Regeneration Research 2019年第6期14卷 1085-1090页

作者： Cheng-Cheng Ying Mei Yang Yong wang Yong-lian Guo wan-li hu Xin-Min Zheng Department of Urology the Central Hospital of WuhanTongji Medical CollegeHuazhong University of Science and Technology Department of Endocrinology Tongren Hospital of Wuhan University (Wuhan Third Hospital) Department of Urology Zhongnan Hospital of Wuhan University

Although the remaining nerve tissue can regenerate and partly restore erectile function when the cavernous nerve is compressed/severed and function lost, the limited regenerative ability of these nerve tissues often fails to meet clinical needs. Adipose-derived stem cells are easy to obtain and culture, and can differentiate into neural cells. Their proliferation rate is easy to control and they may be used to help restore injured cavernous nerve function. Sprague-Dawley male rats(n = 45) were equally randomized into three groups: fifteen rats as a sham-operated group, fifteen rats as a bilateral nerve crush(BINC) group(with no further intervention), fifteen rats as a BINC with intracavernous injection of one million neural-like cells from adipose-derived stem cells(NAS)(BINC + NAS) group. After 4 weeks, erectile function was assessed by stimulating the cavernous body. The number of myelinated axons in the dorsal cavernous nerve was determined by toluidine blue staining. The area of neuronal nitric oxide synthase-positive fibers in the dorsal penile nerve was measured by immunohistochemical staining. Masson staining was used to analyze the ratio of smooth muscle to collagen in penile tissue. The results demonstrate that maximal intracavernous pressure, the ratio of maximal intracavernous pressure to mean arterial pressure, the numbers of myelinated axons and neuronal nitric oxide synthase-positive fibers in the dorsal penile nerve, and the ratio of smooth muscle to collagen could be increased after cell transplantation. These findings indicate that neural-like cells from adipose-derived stem cells can effectively alleviate cavernous nerve injury and improve erectile function. All animal experiments were approved by the Animal Ethics Committee of huazhong University of Science and Technology, China(approval No. 2017-1925) on September 15, 2017.

关键词： nerve regeneration adipose-derived neural stem cells corpus cavernosum cavernous nerve erectile dysfunction radical prostatectomy neurons cell differentiation neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Numerical investigation of sinusoidal pulsating gas intake to intensify the gas-slag momentum transfer in the top-blown smelting furnace

引用

International Journal of Minerals,Metallurgy and Materials 2024年第2期31卷 301-314页

作者： Zhanghao wan Shiliang Yang Desong Kong Dongbo li Jianhang hu hua wang State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization Kunming University of Science and TechnologyKunming 650093China Southwest Copper Branch Yunnan Copper Co.Ltd.Kunming 650102China

The variation characteristics of bubble morphology and the thermal-physical properties of bubble boundary in the top-blown smelting furnace were explored by means of the computational fluid dynamics *** essential aspects of the fluid phase(e.g.,splashing volume,dead zone of copper slag,and gas penetration depth)were explored together with the effect of sinusoidal pulsating gas intake on the momentum-transfer performance between *** results illustrated that two relatively larger vortices and two smaller vortices appear in the bubble waist and below the lance,*** expansion of larger ones as well as the shrinking of smaller ones combine to cause the contraction of the bubble *** to the results of the case with a fixed gas injection velocity(V_(g)=58 m/s),the splashing volume and dead zone volume of the slag under the V_(g)=58+10sin(2πt)condition are reduced by 24.9%and 23.5%,respectively,where t represents the instant *** penetration depth and slag motion velocity of the latter are 1.03 and 1.31 times high-er than those of the former,respectively.

关键词： top-blown smelting furnace pulsed flow volume of fluid penetration depth splashing volume

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

2D–3D dual carbon layer confined ultrasmall VN nanoparticles for improving lithium-ion storage in hybrid capacitors

引用

Rare Metals 2024年第1期43卷 65-75页

作者： Zhao-Wei hu hui-Fang li Peng wang wan-li wang Lei Yang Xiao-Jun wang Zhi-Ming liu College of Electromechanical Engineering Shandong Engineering Laboratory for Preparation and Application of High-Performance Carbon-MaterialsQingdao University of Science&TechnologyQingdao 266061China Research Center for Intelligent and Wearable Technology College of Textiles and ClothingQingdao UniversityQingdao 266071China

lithium-ion capacitors(liCs) of achieving high power and energy density have garnered significant attention. However, the kinetics unbalance between anode and cathode can impede the application of liCs. Vanadium nitride(VN) with a high theoretical specific capacity(~ 1200 m Ah·g^(-1)) is a better pseudocapacitive anode to match the response of cathode in liCs. However, the insertion/extraction of li-ions in VN's operation results in significant volume expansion. Herein, the VN/N-r GO-5composite that three-dimentional(3D) dicyandiamidederived-carbon(DDC) tightly wrapped VN quantum dots(VN QDTs) on two-dimentional(2D) reduced graphene oxid(r GO) was prepared by a facile strategy. The VN QDTs can reduce ion diffusion length and improve charge transfer kinetics. The 2D r GO as a template provides support for nanoparticle dispersion and improves electrical conductivity. The 3D DDC tightly encapsulated with VN QDTs mitigates agglomeration of VN particles as well as volume expansion. Correspondingly, the liCs with VN/Nr GO-5 composite as anode and activated carbon(AC) as cathode were fabricated, which exhibits a high energy density and power density. Such strategy provides a perspective for improving the electrochemical properties of liC anode materials by suppressing volume expansion and enhancing conductivity.

关键词： Vanadium nitride(VN)quantum dots Reduced graphene oxide(rGO)nanosheets Dicyandiamide-derived-carbon 2D–3D dual carbon layer lithium-ion capacitors

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinical features and prognosis of multiple myeloma and orbital extramedullary disease:Seven cases report and review of literature

引用

World Journal of Clinical Cases 2022年第33期10卷 12365-12374页

作者： wan-li hu Jia-Yin Song Xin li Xiao-Jiao Pei Jia-Jia Zhang Man Shen Ran Tang Zhen-Yu Pan Zhong-Xia huang Department of Hematology Multiple Myeloma Medical Center of BeijingBeijing Chao-Yang HospitalCapital Medical UniversityBeijing 100043China Department of Radiology Beijing Chao-Yang HospitalCapital Medical UniversityBeijing 100043China

BACKGROUND Multiple myeloma(MM)complicated with extramedullary disease(EMD)has a poor prognosis and is a limiting factor in the treatment of MM,and no standard treatment is recommended in international *** studies have reported MM with periorbital *** SUMMARY In this paper,the clinical characteristics and survival of seven patients with multiple myeloma and orbital are described and *** common ocular symptoms were blurred vision,proptosis and/or eye movement disorders,IgG type MM may be a risk factor for orbital *** them,six patients were treated with bortezomib-based *** median overall survival(OS)and progression free survival for the entire cohort were 48 and 33 mo,respectively,which was much worse than the OS reported for MM patients without orbital *** Orbital MM may have significantly shortened survival for the entire cohort,so multidisciplinary collaboration is emphasized and recommended in the diagnosis and treatment of these difficult cases.

关键词： Multiple myeloma Extramedullary disease Periorbital Treatment Survival Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The effect of platelet-rich plasma on cavernous nerve regeneration in a rat model

引用

Asian Journal of Andrology 2009年第2期11卷 215-221页

作者： Xie-Gang Ding Shi-Wen li Xin-Min Zheng li-Quan hu wan-li hu Yi Luo Research Center of Urology and Andrology Zhongnan HospitalWuhan UniversityWuhan 430071China

The aim of this study was to investigate the effect of platelet-rich plasma(PRP)on cavernous nerve(CN)regeneration and functional status in a nerve-crush rat ***-four Sprague-Dawley male rats were randomly divided into three equal groups:eight had a sham operation,eight underwent bilateral nerve crushing with no further intervention and eight underwent bilateral nerve crushing with an immediate application of PRP on the site of *** function was assessed by CN electrostimulation at 3 months and nerve regeneration was assessed by toluidine blue staining of CN and nicotinamide adenine dinucleotide phosphate(NADPH)-diaphorase staining of penile *** months after surgery,in the group that underwent bilateral nerve crushing with no further intervention,the functional evaluation showed a lower mean maximal intracavernous pressure(ICP)and maximal ICP per mean arterial pressure(MAP)with CN stimulation than those in the sham *** the group with an immediate application of PRP,the mean maximal ICP and maximal ICP/MAP were significantly higher than those in the injured control ***,the group with the application of PRP had more myelinated axons of CNs and more NADPH-diaphorase-positive nerve fibres than the injured control group but fewer than the sham *** results show that the application of PRP to the site of CN-crush injury facilitates nerve regeneration and recovery of erectile *** research indicates that clinical application of PRP has potential repairing effect on CN and peripheral nerves.

关键词： platelet rich plasma impotence erectile dysfunction nerve regeneration

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Feasibility of using Vis-NIR spectroscopy and PXRF spectrometry to estimate regional soil cadmium concentration

引用

Journal of Environmental Sciences 2024年第11期145卷 88-96页

作者： Mengxue wan Fan Ya’nan Wentao Jiao Wenyou hu Mingchao Lyu Weidong li Chuanrong Zhang Biao huang Key Laboratory of Soil Environment and Pollution Remediation Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China Department of Environmental Science Zhejiang UniversityHangzhou 310058China Guangdong Provincial Academy of Environmental Science Guangzhou 510045China Department of Geography University of ConnecticutStorrsCT 06269USA

Conventionally,soil cadmium(Cd)measurements in the laboratory are expensive and timeconsuming,involving complex processes of sample preparation and chemical *** study aimed to identify the feasibility of using sensor data of visible near-infrared reflectance(Vis-NIR)spectroscopy and portable X-ray fluorescence spectrometry(PXRF)to estimate regional soil Cd concentration in a time-and *** sensor data of Vis-NIR and PXRF,and Cd concentrations of 128 surface soils from Yunnan Province,China,were ***-product analysis(OPA)was used for synthesizing the sensor data and Granger-Ramanathan averaging(GRA)was applied to fuse the model *** neural network(ANN)models were built using Vis-NIR data,PXRF data,and OPA data,*** showed that:(1)ANN model based on PXRF data performed better than that based on Vis-NIR data for soil Cd estimation;(2)Fusion methods of both OPA and GRA had higher predictive power(R^(2))=0.89,ratios of performance to interquartile range(RPIQ)=4.14,and lower root mean squared error(RMSE)=0.06,in ANN model based on OPA fusion;R^(2)=0.88,RMSE=0.06,and RPIQ=3.53 in GRA model)than those based on either Vis-NIR data or PXRF *** conclusion,there exists a great potential for the combination of OPA fusion and ANN to estimate soil Cd concentration rapidly and accurately.

关键词： Artificial neural network Outer-product analysis Granger-Ramanathan averaging Soil Cd concentration Fusion method

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

New insights into the DPR mechanism of elastic energy released by polymer gel for enhanced oil recovery

引用

Petroleum 2024年第3期10卷 539-547页

作者： hu Jia Junyi Wu Shaowei Wu Yanbin liang Minghao wang Xiaojin wan Pengwu li State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengduChina CNOOC Zhanjiang Branch ZhanjiangChina Oil Production Technology Institute of PetroChina Dagang Oilfield Company TianjinChina

Polymer gel was widely used as water shutoff agent in mature oil *** the results of single-phase plugging experiments show that the plugging rate of the polymer gel to the oil phase is lower than that of the water ***,the disproportionate permeability reduction(DPR)mechanism of polymer gels still remains *** this paper,we used four gel formulations including polyethyleneimine(PEI)and phenol-formaldehyde crosslinked gel with and without adding laponite to investigate the effect of gel elastic property on the water shutoff *** result of sand pack flooding experiments shown that the gel with higher elastic modulus has better effects on decreasing water cut and increasing oil *** adding laponite,the elastic modulus of phenol-formaldehyde crosslinked gel increased from 64.2 Pa to 192 Pa,and the elastic modulus of PEI crosslinked gel increased from 27.4 Pa to 36.5 *** to the phenol-formaldehyde-HAPM gel,the oil recovery of laponite-phenol-formaldehyde-HPAM gel increased by 5.2%and the maximum water cut decreased by 8.3%.Besides,comparing with PEI-HPAM gel,the oil recovery of laponite-PEI-HPAM gel increased by 2.7%and the water cut dropped by 27.8%.In the meanwhile,the laponite-phenol-formaldehyde-HPAM gel with higher elastic modulus obviously swells in the formation water but almost remains constant in oil at 105℃.The mass of gel soaked in the formation water increased from 42 g to 96 g and the gel volume increased by 300%within 48 *** study improves the understanding of the DPR mechanism of polymer gel for water shutoff.

关键词： Gel elasticity Water shutoff DPR Laponite Oil recovery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evaluation of the Shallow Gas Hydrate Production Based on the Radial Drilling-Heat Injection-Back Fill Method

引用

Journal of Ocean University of China 2024年第1期23卷 119-128页

作者： CHEN Qiang wan Yizhao WU Nengyou SUN Jianye wanG Jian liU Changling li Yanlong li Chengfeng hu Gaowei Key Laboratory of Gas Hydrate Ministry of Natural ResourcesQingdao 266071China Laboratory for Marine Mineral Resources Laoshan LaboratoryQingdao 266071China CNPC Offshore Engineering Company limited Beijing 100028China Technology Innovation Center for Marine Methane Monitoring Ministry of Natural ResourcesQingdao 266071China

It has been evidenced that shallow gas hydrate resources are abundant in deep oceans *** geological back-ground,occurrence,and other characteristics differ significantly from deep-seated *** of the high risk of well construction and low production efficiency,they are difficult to be recovered by using conventional oil production *** a result,this paper proposes an alternative design based on a combination of radial drilling,heat injection,and backfilling ***-branch holes are used to penetrate shallow gas hydrate reservoirs to expand the depressurization area,and heat injection is utilized as a supplement to improve gas *** information collected from an investigation site close to the offshore production well in the South China Sea is used to assess the essential components of this plan,including well construction stability and gas production *** demonstrates that the hydraulic fracturing of the 60mbsf overburden layer can be prevented by regulating the drilling fluid ***,the traditional well structure is unstable,and the suction anchor is advised for better mechanical *** gas produc-tion rate can be significantly increased by combining hot water injection and depressurization ***,the suitable produc-tion equipment already in use is discussed.

关键词： shallow gas hydrate trail production radial drilling-heat injection-back fill method experimental and numerical simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The preparation and performance analysis of zirconium-modified aluminum phosphate-based high-temperature(RT-1500℃)resistant adhesive for joining alumina in extreme environment

引用

Journal of Advanced Ceramics 2024年第7期13卷 911-932页

作者： Jingxuan liu Yange wan Bo Xiao Jiancun li Zhanming hu Ruoyu Zhang Xiaoxia hu Jiachen liu Guoshuai Cai Hongli liu Mingchao wang College of Science Civil Aviation University of ChinaTianjin 300300China Department of Safety Engineering Civil Aviation University of ChinaTianjin 300300China Binzhou Beicheng Construction Engineering Materials Testing Co. Ltd.Binzhou 256602China Department of Aviation Engineering Civil Aviation University of ChinaTianjin 300300China School of Materials and Engineering Key Lab of Advanced Ceramics and Machining Technology of Ministry of EducationTianjin UniversityTianjin 300072China

High-temperature-resistant adhesives are critical materials in the aerospace *** zirconium-modified aluminum phosphate-based adhesives developed in this work had the advantage of adjustable thermal expansibility,achieving a high matching of coefficient of thermal expansion(CTE)with *** introduction of zirconium can significantly improve the thermal stability of the adhesive matrix,and the Zr/Al ratio substantially affects the various reaction processes inside the adhesive,especially the types of zirconium-containing *** of the zirconium-containing compounds in the A7Z3 adhesive were ZrO_(2) only when the mass ratio of zirconium hydroxide to aluminum hydroxide was 3:7,which was the key reason why it had the highest *** room-temperature bonding strength of A7Z3 after heat treatment at 1500℃reached 67.2 *** pretreatment at 1500℃,the high-temperature bonding strength of A7Z3 was greater than 50 MPa in the range of(room temperature)RT-1000℃.After 40 thermal cycles between RT and 1500℃,the bonding strength still reached 10 *** bonding occurred at temperatures below 1000℃,while chemical bonding dominated above 1000℃based on the generation of Al5BO9 and mullite at the interfaces.

关键词： high-temperature-resistant adhesive thermal expansion property zirconium-modified aluminum phosphate bonding performance thermal cycling bonding mechanism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A vertical track nonlinear energy sink

引用

Applied Mathematics and Mechanics(English Edition) 2024年第6期45卷 931-946页

作者： Meng li hu DING Shanghai Key Laboratory of Mechanics in Energy Engineering School of Mechanics and Engineering ScienceShanghai Frontier Science Center of MechanoinformaticsShanghai UniversityShanghai 200444China

Eliminating the effects of gravity and designing nonlinear energy sinks(NESs)that suppress vibration in the vertical direction is a challenging task with numerous damping *** this paper,the dynamic design of a vertical track nonlinear energy sink(VTNES)with zero linear stiffness in the vertical direction is proposed and realized for the first *** motion differential equations of the VTNES coupled with a linear oscillator(LO)are *** the strong nonlinearity considered of the VTNES,the steady-state response of the system is analyzed with the harmonic balance method(HBM),and the accuracy of the HBM is verified *** this basis,the VTNES prototype is manufactured,and its nonlinear stiffness is *** damping effect and dynamic characteristics of the VTNES are studied theoretically and *** results show that the VTNES has better damping effects when strong modulation responses(SMRs)***,even for small-amplitude vibration,the VTNES also has a good vibration suppression *** sum up,in order to suppress the vertical vibration,an NES is designed and developed,which can suppress the vertical vibration within certain ranges of the resonance frequency and the vibration intensity.

关键词： track nonlinear energy sink(TNES) vertical direction gravity nonlinear stiffness harmonic balance method(HBM) vibration control

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：