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大型复杂锻件打磨路径的智能化规划方法

机械工程学报 2024年第11期60卷 216-225页

作者：闫守鑫王伟苏鹏飞贠超北京航空航天大学机械工程及自动化学院北京100191

大型复杂锻件作为能源、船舶、交通等领域的主要承力构件,对后处理的尺寸精度和表面质量要求高,实现大型复杂锻件的自动化打磨是锻造行业亟待解决的共性难题。主要技术障碍之一是:大型复杂锻件存在较大的热变形、多种随机锻造缺陷,难以... 详细信息

大型复杂锻件作为能源、船舶、交通等领域的主要承力构件,对后处理的尺寸精度和表面质量要求高,实现大型复杂锻件的自动化打磨是锻造行业亟待解决的共性难题。主要技术障碍之一是:大型复杂锻件存在较大的热变形、多种随机锻造缺陷,难以自动生成打磨加工路径。首先提出了一种大型复杂锻件随机缺陷识别算法,通过随机采样一致性算法(Random sample consensus,RANSAC)与改进迭代最近点(Modified iterative closest point,M-ICP)算法相结合,对标准件点云与锻件点云进行配准,得到需要打磨的随机缺陷点云;接着,按照缺陷面积大小,对随机缺陷点云进行的分类,建立了打磨路径生成策略;然后,利用随机缺陷点云中的位置坐标信息,不需要CAD模型,直接生成了机器人打磨路径;最后,开展了大型复杂锻件的机器人打磨实验,实验结果表明:打磨路径智能化生成方法准确识别了随机锻造缺陷特征,正确规划了机器人打磨路径,提高了打磨效率和打磨质量,为大型复杂锻件后处理加工提供了技术方法。

关键词：缺陷识别智能化打磨路径规划大型复杂锻件

混合联肢PEC墙结构基于合理失效模式的性能化设计方法研究

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振动与冲击 2024年第7期43卷 266-277,289页

作者：周巧玲赵仕兴苏明周石韵四川省建筑设计研究院有限公司成都610041 西安建筑科技大学土木工程学院西安710055 西安石油大学土木工程学院西安710065

基于性能化设计理念,提出了混合联肢PEC墙结构基于合理失效模式的性能化设计方法:以结构达目标位移时实现合理失效模式作为性能目标,基于能量平衡原理确定结构设计基底剪力,并给出符合失效模式的侧向力分布;依据给定目标塑性耦连比分别... 详细信息

基于性能化设计理念,提出了混合联肢PEC墙结构基于合理失效模式的性能化设计方法:以结构达目标位移时实现合理失效模式作为性能目标,基于能量平衡原理确定结构设计基底剪力,并给出符合失效模式的侧向力分布;依据给定目标塑性耦连比分别求解钢连梁和PEC墙肢底部加强区内力需求;采用塑性设计方法设计钢连梁和PEC墙肢底部加强区截面,采用弹性设计方法设计PEC墙肢非加强区截面,保证结构实现预期性能目标。依据提出的基于合理失效模式的性能化设计方法,设计了12层混合联肢PEC墙算例结构,对其进行Pushover分析和弹塑性动力时程分析,验证了该方法的可行性。基于合理失效模式的性能化设计方法设计的混合联肢PEC墙结构抗震性能良好,地震作用下,各层钢连梁首先剪切屈服耗散能量,然后PEC墙肢底部形成弯曲塑性铰,塑性铰分布及发展过程符合预期,实现了“两阶段耗能体系”设计目标。

关键词：混合联肢墙抗震性能目标位移合理失效模式性能化设计方法

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我国数据要素政策主题演化与识别分析

图书情报工作 2024年第16期68卷 90-103页

作者：苏婉于森禚传阳吉林大学商学与管理学院长春130012

[目的/意义]直面数据要素特征复杂性及外部不确定性不断叠加的环境,亟须分析我国数据要素政策发展重点,掌握其演化趋势和区域主题,对于推动数据要素领域发展具有重要意义。[方法/过程]选取我国31个省(市、自治区)的597份数据要素政策文... 详细信息

[目的/意义]直面数据要素特征复杂性及外部不确定性不断叠加的环境,亟须分析我国数据要素政策发展重点,掌握其演化趋势和区域主题,对于推动数据要素领域发展具有重要意义。[方法/过程]选取我国31个省(市、自治区)的597份数据要素政策文本,划分6个阶段和4个区域,从时间和空间两个维度采用DTM模型和LDA模型分别对其进行主题演化分析和区域主题识别。[结果/结论]研究发现,不同阶段各个主题强度随时间演进发生变化,同一主题不同阶段关键词也有所不同,归纳总结3条主要的主题演化路径;不同区域数据要素政策在重点领域上存在差异,但在推动数据要素发展方面政策导向和落地举措存在相似之处。通过对我国数据要素政策主题演化与识别分析,以期更好把握我国数据要素政策发展脉络,为数据要素领域有序发展提供有力支撑。

关键词：数据要素政策分析主题演化主题识别

Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia:randomized trials and multiomics analysis

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Military Medical Research 2024年第1期11卷 19-33页

作者： Liang-Kun Guo Yi su Yu-Ya-Nan Zhang Hao Yu Zhe Lu Wen-Qiang Li Yong-Feng Yang Xiao Xiao Hao Yan Tian-Lan Lu Jun Li yun-Dan Liao Zhe-Wei Kang Li-Fang wang Yue Li Ming Li Bing Liu Hai-Liang Huang Lu-Xian Lv Yin Yao yun-Long Tan Gerome Breen Ian Everall Hong-Xing wang Zhuo Huang Dai Zhang Wei-Hua Yue Institute of Mental Health Peking University Sixth HospitalBeijing 100191China National Clinical Research Center for Mental Disorders Peking University Sixth HospitalBeijing 100191China NHC Key Laboratory of Mental Health and Research Unit of Diagnosis and Treatment of Mood Cognitive Disorder(2018RU006) Chinese Academy of Medical SciencesBeijing 100191China Peking University Huilongguan Clinical Medical School Beijing Huilongguan HospitalBeijing 100096China Department of Psychiatry Jining Medical UniversityJining 272067ShandongChina Henan Key Lab of Biological Psychiatry the Second Affiliated Hospital of Xinxiang Medical UniversityXinxiang 435001HenanChina Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and yunnan Province Kunming Institute of ZoologyChinese Academy of SciencesKunming 650223China Institute of Psychiatry Psychology and NeuroscienceKing’s College LondonLondon WC2R 2LSUK State Key Laboratory of Cognitive Neuroscience and Learning Beijing Normal UniversityBeijing 100875China Analytic and Translational Genetics Unit Massachusetts General HospitalBostonMA 02114USA Stanley Center for Psychiatric Research the Broad Institute of MIT and HarvardCambridgeMA 02141USA Department of Medicine Harvard Medical SchoolBostonMA 02115USA Department of Biostatistics and Computational Biology School of Life SciencesFudan UniversityShanghai 200438China Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijing 100053China State Key Laboratory of Natural and Biomimetic Drugs Key Laboratory for Neuroscience for Ministry of EducationSchool of Pharmaceutical SciencesPeking University Health Science CenterBeijing 100191China PKU-IDG/McGovern Institute for Brain Research Peking UniversityBeijing 100871China Chinese Institute for Brain Research Beijing 102206China

Background:Choosing the appropriate antipsychotic drug(APD)treatment for patients with schizophrenia(SCZ)can be challenging,as the treatment response to APD is highly variable and difficult to predict due to the lack of effective *** studies have indicated the association between treatment response and genetic and epigenetic factors,but no effective biomarkers have been ***,further research is imperative to enhance precision medicine in SCZ ***:Participants with SCZ were recruited from two randomized *** discovery cohort was recruited from the CAPOC trial(n=2307)involved 6 weeks of treatment and equally randomized the participants to the Olanzapine,Risperidone,Quetiapine,Aripiprazole,Ziprasidone,and Haloperidol/Perphenazine(subsequently equally assigned to one or the other)*** external validation cohort was recruited from the CAPEC trial(n=1379),which involved 8 weeks of treatment and equally randomized the participants to the Olanzapine,Risperidone,and Aripiprazole ***,healthy controls(n=275)from the local community were utilized as a genetic/epigenetic *** genetic and epigenetic(DNA methylation)risks of SCZ were assessed using the polygenic risk score(PRS)and polymethylation score,*** study also examined the genetic-epigenetic interactions with treatment response through differential methylation analysis,methylation quantitative trait loci,colocalization,and promoteranchored chromatin *** learning was used to develop a prediction model for treatment response,which was evaluated for accuracy and clinical benefit using the area under curve(AUC)for classification,R^(2) for regression,and decision curve ***:Six risk genes for SCZ(LINC01795,DDHD2,SBNO1,KCNG2,SEMA7A,and RUFY1)involved in cortical morphology were identified as having a genetic-epigenetic interaction associated with treatment *** developed and externally validated predictio

关键词： Schizophrenia Antipsychotic drug Treatment response Prediction model Genetics Epigenetics

Atom-referenced and stabilized soliton microcomb

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Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 2-8页

作者： Rui Niu Shuai wan Tian-Peng Hua Wei-Qiang wang Zheng-Yu wang Jin Li Zhu-Bo wang Ming Li Zhen Shen Yu Robert sun Shui-Ming Hu Brent ELittle Sai Tak Chu Wei Zhao Guang-Can Guo Chang-Ling Zou yun-Feng Xiao Wen-Fu Zhang Chun-Hua Dong State Key Laboratory of Transient Optics and Photonics Xi’an Institute of Optics and Precision MechanicsChinese Academy of SciencesXi’an 710119China CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China University of Chinese Academy of Sciences Beijing 100049China Department of Chemical Physics University of Science and Technology of ChinaHefei 230026China Department of Physics and Materials Science City University of Hong KongHong Kong 999077China State Key Laboratory for Mesoscopic Physics and Frontiers Science Center for Nano-optoelectronics School of PhysicsPeking UniversityBeijing 100871China

For the applications of the frequency comb in microresonators,it is essential to obtain a fully frequency-stabilized microcomb laser *** this study,we present a system for generating a fully atom-referenced stabilized soliton *** pump light around 1560.48 nm is locked to an ultra-low-expansion(ULE)*** pump light is then frequency-doubled and referenced to the atomic transition *** repetition rate of the soliton microcomb is injection-locked to an atomic-clockstabilized radio frequency(RF)source,leading to mHz stabilization at 1 *** a result,all comb lines have been frequencystabilized based on the atomic reference and the ULE cavity,achieving a very high precision of approximately 18 Hz at 1 s,corresponding to the frequency stability of 9.5×10^(-14).Our approach provides a fully stabilized microcomb experiment scheme with no requirement of f-2f technique,which could be easily implemented and generalized to various photonic platforms,thus paving the way towards the ultraprecise optical sources for high precision spectroscopy.

关键词： microcavity frequency comb dissipative Kerr solitons fully stabilized microcomb

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U型平板微热管LED散热器散热性能分析

农业工程学报 2024年第9期40卷 227-235页

作者：余万韩煜王岗苏华山胡涛苏良彬董裴芹三峡大学水电机械设备设计与维护湖北省重点实验室宜昌443002 三峡大学机械与动力学院宜昌443002

针对目前LED表面发热量较大,局部温度过高,而导致其使用寿命减少的问题,该研究以平板微热管为核心传热元件,与锯齿形翅片结合,设计了一种U型平板微热管散热器。采用试验和仿真模拟相结合的方法,对不同风速、翅片结构、翅高及翅间距等关... 详细信息

针对目前LED表面发热量较大,局部温度过高,而导致其使用寿命减少的问题,该研究以平板微热管为核心传热元件,与锯齿形翅片结合,设计了一种U型平板微热管散热器。采用试验和仿真模拟相结合的方法,对不同风速、翅片结构、翅高及翅间距等关键影响因素进行分析。结果表明:通过对比分析U型平板微热管在两种室外工况下各测点试验值和模拟值,散热稳定后温度的最大误差分别为4.2%和6.7%,验证了模型的可靠性。风速分别为0.5和3.0 m/s时,锯齿型翅片都具有良好的散热性能。当风速为3.0 m/s时,锯齿型翅片、W型翅片、直翅片散热器稳定后热源温度分别为34.3、35.5和39.1℃。为找到最佳工况和结构,进行了正交分析,当室外风速为3.5 m/s,锯齿型翅片翅高为12 mm,翅间距为8 mm时,U型热管具有较佳的散热性能。研究结果可为LED散热系统的设计提供数据参考和设计思路,拓宽LED光源的应用范围。

关键词：数值模拟试验散热 U型平板微热管翅片正交分析

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通信运营商数据中台设计思路分析

通信电源技术 2024年第3期41卷 149-151页

作者：苏婉安徽电信规划设计有限责任公司安徽合肥230031

文章针对数据中台在通信运营商中的建设与应用,浅析数字中台与数据资产概念与作用,明确在云计算、大数据、人工智能以及物联网等数字技术背景下运营商数智化发展的必然趋势。同时,探讨现阶段通信运营商数字中台设计与建设难点,理清通信... 详细信息

文章针对数据中台在通信运营商中的建设与应用,浅析数字中台与数据资产概念与作用,明确在云计算、大数据、人工智能以及物联网等数字技术背景下运营商数智化发展的必然趋势。同时,探讨现阶段通信运营商数字中台设计与建设难点,理清通信运营商中台建设总体设计思路和方案,明确数字中台的研究和工作方向。

关键词：数据中心数据资产设计方案智能操作

基于R-Vine Copula的财险公司经济资本度量与分散化效益研究

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保险研究 2024年第6期 55-69页

作者：郑敏郑苏晋刘皖中央财经大学保险学院中央财经大学中国精算研究院中国财产再保险有限责任公司

经济资本在保险公司内部风险管理和资本配置等方面发挥着至关重要的作用,它能够准确地反映保险公司所面临的风险状况,并为风险的有效管理与资本的合理配置提供重要依据。本文以财险公司的经济资本为研究对象,在传统资产负债模型的框架下... 详细信息

经济资本在保险公司内部风险管理和资本配置等方面发挥着至关重要的作用,它能够准确地反映保险公司所面临的风险状况,并为风险的有效管理与资本的合理配置提供重要依据。本文以财险公司的经济资本为研究对象,在传统资产负债模型的框架下,通过R-Vine Copula风险聚合方法对资产和负债进行联合建模,进而计算经济资本并分析相应的分散化效益,并与监管方法进行比较。研究结果表明财险公司的资产和负债存在复杂的依赖关系,利用Vine结构可以更加全面、精确地描述这两者之间的非对称和非线性相关性,同时拟合数据的尾部特征,进而获得更为稳健的净资本估计量,以及更为真实的经济资本需求和相应的分散效益。相较于偿付能力规则下的线性聚合方法,R-Vine Copula风险聚合方法能充分利用资产变量和负债变量之间的相关性信息,适宜用作计算经济资本的内部模型。该模型以风险为导向,为研究资产和负债的联动关系提供一个新的方法,可以帮助财险公司更好地管理风险,并提升整体业务的稳定性和可持续发展能力。

关键词：经济资本 R-Vine Copula 分散化效益破产概率

Prediction of mechanical ventilation outcome by early abdominal-visceral-blood-flow-and-function score in critically ill patients after cardiopulmonary bypass in the ICU: A prospective observational study

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Journal of Intensive Medicine 2024年第1期4卷 101-107页

作者： Chaofu Yue Longxiang su Jun wang Na Cui Yuankai Zhou Wei Cheng Bo Tang Xi Rui Huaiwu He yun Long Department of Intensive Care Unit Peking Union Medical College HospitalBeijingChina Department of Intensive Care Unit Qujing First People’s HospitalQujingYunnanChina Department of Intensive Care Unit Shiyan People’s Hospital of Bao’an DistrictShenzhenGuangdongChina

Background:Abdominal organs are important organs that sense and respond to ischemia and hypoxia,but there are few evaluation *** use ultrasonography to evaluate abdominal organ function and blood flow in patients with mechanical ventilation(MV)after cardiopulmonary bypass and to obtain a semiquantitative score for abdominal organ function and blood ***:Patients with cardiopulmonary bypass in the Critical Care Department of Peking Union Medical College Hospital in China from March to July 2021 were enrolled in this prospective observational *** correlation of the abdominal-visceral-blood-flow-and-function score(AVBFS)with the duration of MV,number of days spent in the intensive care unit(ICU),acute physiology and chronic health evaluation II(APACHE-II),sequential organ failure assessment(SOFA),lactate,epinephrine,and norepinephrine use was analyzed,and the results were used to assess the predictive value of the receiver operating characteristic curve(ROC)regression analysis score for the duration of ***:Of the 92 patients who underwent cardiopulmonary bypass,41 were finally *** AVBFS were significantly correlated with the duration of MV,number of days spent in the ICU,APACHE-II score,SOFA score,and norepinephrine use *** AVBFS in a group of patients using ventilators≥36 h were significantly higher than those obtained for a group of patients using ventilatorssults for the AVBFS at 0-12 h after ICU admission were as follows:area under the ROC curve(AUC)=0.876(95%confidence interval[CI]:0.767 to 0.984),cut-off value=2.5,specificity=0.842,and sensitivity=***:Abdominal visceral organ function and blood perfusion can be used to evaluate gastrointestinal *** is related to early and late extubation after cardiac surgery.

关键词： Ultrasonic evaluation Abdominal-visceral-blood-flow-and-function score(AVBFS) Gastrointestinal dysfunction Mechanical ventilation Cardiopulmonary bypass