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A bibliometric analysis of global research output on health and human rights(1900–2017)

Global Health Research and Policy 2018年第1期3卷 67-76页

作者： waleed M.Sweileh Department of Physiology Pharmacology/ToxicologyDivision of Biomedical SciencesCollege of Medicine and Health SciencesAn-Najah National UniversityNablusPalestine

Background:Baseline data on global research activity on health and human rights(HHR)needs to be assessed and analyzed to identify research gaps and to prioritize funding and research ***,the aim of this study was to assess the growth of publications and research pattern on ***:A bibliometric methodology was *** on HHR was retrieved using SciVerse Scopus for the study period from 1900 to *** different search scenarios with different keyword combinations were used to retrieve the required *** types of documents published in peer-reviewed journals,including editorials,were *** search strategy was ***:In total 6513 documents were retrieved with an h-index of 88 and an average of 9.8 citations per *** on HHR field started as early as 1950 but showed a steep rise in the past two *** of author keywords revealed that HIV/AIDS,mental health,maternal and reproductive health,violence,ethics,torture,and refugees were most commonly encountered *** journal“Health and Human Rights”was most active(n=467;7.2%)in this ***,documents that appeared in The Lancet received the highest impact(29.5 citations per document).The United States of America produced the most in this field(n=1817;27.9%).Researchers in the region of Americas participated in approximately 45%of the retrieved documents while researchers in the Eastern Mediterranean region had the least contribution(2.5%).Researchers in high-income countries contributed to approximately 78%of the retrieved documents while researchers in low-income countries contributed to less than 5%of the retrieved *** data were standardized by population size,the research output from high-income countries was approximately four documents per one million *** middle-income countries,the research output was 0.3 document per one million *** low-income countries,the research output was 0.5 docu

关键词： Health Human rights Bibliometric analysis

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Comprehensive review into the challenges of gastrointestinal tumors in the Gulf and Levant countries

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World Journal of Clinical Cases 2020年第3期8卷 487-503页

作者： Rare Tumors GI Group Fadi Farhat Abdulaziz al Farsi Ahmed Mohieldin Bassim al Bahrani Eman Sbaity Hassan Jaffar Joseph Kattan Kakil Rasul Khairallah Saad Tarek Assi waleed El Morsi Rafid A Abood 不详 Hammoud Hospital UMC Saida PO Box 652Lebanon Medical Oncology Department Royal HospitalMuscat PO Box 1331Oman Medical Oncology Department Kuwait Cancer Control CenterKuwait PO Box 42262Kuwait Division of General Surgery American University of BeirutBeirut 11072180Lebanon Oncology Department Tawam HospitalAl Ain PO Box 15258United Arab Emirates Hemato-oncology Department Hotel Dieu de FranceBeirutLebanon Hemato-oncology Department National Center for Cancer Care and ResearchDohaQatar Pathology Department Institute National de PathologicBeirutLebanon Oncology Department Faculty of MedicineSaint-Joseph UniversityBeirutLebanon Pfizer Oncology-Emerging Markets Dubai Media CityDubaiUnited Arab Emirates Oncology Department Basra College of MedicineBasraIraq

although gastrointestinal stromal tumors(GISTs)are rare,with an incidence of 1/100000 per year,they are the most common sarcomas in the peritoneal *** considerable progress in the diagnosis and treatment of GIST,about half of all patients are estimated to experience *** only two drugs,sunitinib and regorafenib,approved by the Food and Drug Administration,selecting treatment options after imatinib failure and coordinating multidisciplinary care remain *** addition,physicians across the Middle East face some additional and unique challenges such as lack of published local data from clinical trials,national disease registries and regional scientific research,limited access to treatment,lack of standardization of care,and limited access to mutational *** global guidelines set a framework for the management of GIST,there are no standard local guidelines to guide clinical practice in a resource-limited ***,a group of 11 experienced medical oncologists from across the Gulf and Levant region,part of the Rare Tumors Gastrointestinal Group,met over a period of one year to conduct a narrative review of the management of GIST and to describe regional challenges and gaps in patient management as an essential step to proposing local clinical practice recommendations.

关键词： Gastrointestinal stromal tumors Diagnosis Disease management Treatment Challenges Middle East

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Glycated Hemoglobin HbA1c:Permittivity Experimental Applications with Some Mathematical Concepts,Temperature and Frequency Variations

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Journal of Renewable Materials 2022年第9期10卷 2335-2354页

作者： Soliman Abdalla Sherif Kandil waleed El-Shirbeeny Fatma Bahabri Department of Physics Faculty of ScienceKing Abdulaziz UniversityJeddahSaudi Arabia Department of Materials Science Institute of Graduate Studies and ResearchAlexandria UniversityAlexandriaEgypt Department of Physics Faculty of ScienceJeddah UniversityJeddahSaudi Arabia

Diabetes disorder turns smoothly to be a global epidemic disorder and the glycated hemoglobin(HbA1c)starts to be an efficient marker of *** dielectric spectroscopy on different human normal-and diabetic-blood samples is used to characterize and to estimate the HbA1c concentration.“dc-”and ac-measurement of the complex conductivity in the temperature range from 280 K up to 320 K,and in the frequency range from one Hz up to 32 MHz have been *** thermal activation energy,ΔEσ,of dc-electric conductivity lies in the range 95 meVal activation energy,ΔEτ,of RBCs relaxation time is aboutΔEτ=140 *** experimental data have been modeled by a physical-model and good fittings have been found between calculated and experimental *** effective number of charges,nG,T,is estimated after Cole and Cole *** has found that nG,T increases with both temperature,T,and with the glycation rate *** increase may shed some light on an effective and possible way to treat(and to detect)diabetes disorders via eliminating the excess electric charges produced by glycation *** present work sheds the light on the possible combination of focused ultrasound with magnetic resonance imaging to study the dielectric-thermal variations of glycated-RBCs,which can lead to very precise and non-invasive monitoring of glycation concentration in vivo and in vitro via magnetic resonance-thermometry.

关键词： Glycated-hemoglobin rate thermal characterization red blood cells RBCs relaxation of RBCs dielectric constant mathematical model

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Impact of Fractures and Diagenesis on Reservoir Potential of Inner Ramp Paleocene Carbonates Exposed in Western Part of the Lesser Himalayas of Pakistan

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Journal of Earth Science 2023年第2期34卷 536-555页

作者： waleed Tariq Gohar Rehman Syed Ahsan Hussain Gardezi Nawaz Ikram National Center of Excellence in Geology University of PeshawarPeshawarKhyber Pakhtunkhwa 25120Pakistan Department of Geology University of PeshawarPeshawarKhyber Pakhtunkhwa 25120Pakistan Geological Survey of Pakistan Azad Jammu&Kashmir DirectorateMuzaffarabad 13100Pakistan Institute of Geology University of Azad Jammu&KashmirMuzaffarabad 13100Pakistan

The outcrop investigations provide a better comprehension to interrelate facies-diagenesis and fracture networks for the evaluation of reservoir potential of the carbonate *** this paper,we targeted Kahi-Section(Nizampur Basin)and Peeran Tangai-Section(Kalachitta Range)to analyze structural-kinematics,Discrete Fracture Network Modelling,microfacies identification and diagenesis to interpret their impact on reservoir potential of Lockhart Limestone(Paleocene).The structural grain within the study area mostly represents the typical east-west trending tight to overturned folds and north-dipping thrust faults that mimic the north-south Indo-Eurasian ***,a second phase of deformation related to east-west compressions also identified which rotated the axes of preexisting *** analysis revealed that extensional fractures are oriented at high angle to bedding and are differentiated into three orthogonal sets trending northeast-southwest,northwest-southeast and east-west,whereas,the shear fractures formed two conjugate sets trending *** Lockhart Limestone was deposited in the inner ramp setting and microfacies types are packstone,wackestone and wacke-packstone with seven sub-microfacies *** has been identified that the Lockhart Limestone has the heterogeneous distribution of diagenetic and tectonic features throughout its *** observed diagenetic sequence is micritization,calcite cementation,dissolution,neomorphism,pyritization and *** results highlight that open and partially filled fractures may provide an interconnected network to promote fluid mobility,leading to higher values of fracture *** porosity values of the pore matrix were greater than fracture,resulting a significant impact on reservoir storage *** contrast,a negative impact on reservoir potential has been shown by stylolites,veins and dissolution ***,based on the overall studies,the Lockhart Limestone reve

关键词： lockhart limestone discrete fracture network modelling facies-diagenesis reservoir potential Nizampur Basin petroleum geology

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An energetic nano-fiber composite based on polystyrene and 1,3,5-trinitro-1,3,5-triazinane fabricated via electrospinning technique

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Defence Technology（防务技术） 2023年第9期27卷 1-8页

作者： Mahmoud Abdelhafiz Ahmed K.Hussein waleed F.Khalil Ahmed Elbeih Military TechnicalCollege(MTC) KobryElkobbahCairoEgypt Safety FuelCycleDepartment NRSRCEgyptianAtomicEnergyAuthority(EAEA)CairoEgypt

Electrospinning is a simple technique used to fabricate polymeric nano-fibrous *** nano-fibers have found a wide range of valuable applications in the biomedical ***,it has not been utilized with solid high explosives ***,the electrospinning technique has been used to fabricate polystyrene(PS)/1,3,5-trinitro-1,3,5-triazinane(RDX)composite *** governed electrospinning parameters,voltage,distance from the collector,flow rate,mandrel rotating speed,time,and solution concentration,that greatly affect the morphology of the obtained nanofibers were *** fabricated PS/RDX nano-fibers were characterized using scanning electron microscopy(SEM),X-ray diffractometer(XRD),and Fourier Transform Infrared(FTIR)*** impact and friction sensitivities of PS/RDX were also *** thermal behavior of the prepared composite and the pure materials were studied by the thermal gravimetric analysis technique(TGA).SEM results proved the fabrication of PS/RDX fibers in the nano-size via *** spectroscopy confirmed the existence of the characteristic functional groups of both PS and RDX in the composite *** sharp peaks showed the conversion of amorphous PS into crystalline shape via electrospinning and also confirmed the formation of PS/RDX *** PS fibers absorbed the heat and increased the onset decomposition of the pure RDX from 181.5 to 200.7℃in the case of PS/RDX ***,PS/RDX nano-fibers showed the relatively low impact and friction sensitivities of 100 J and 360 N *** results could introduce PS/RDX nanofibrous composite in the field of explosives detection with high levels of safety.

关键词： Electrospinning Nano-fibers 1,3,5-Trinitro-1,3,5-triazinane(RDX) Polystyrene(PS) Sensitivity

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New solutions for four novel generalized nonlinear fractional fifth-order equations

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Journal of Ocean Engineering and Science 2024年第1期9卷 59-65页

作者： Mehmet Senol Lanre Akinyemi Henrietta Nkansah waleed Adel Nevsehir HacıBekta¸s Veli University Department of MathematicsNevsehirTurkey Department of Mathematics Lafayette CollegeEastonPennsylvaniaUSA Department of Mathematics University of Cape CoastCape CoastGhana Department of Mathematics and Engineering Physics Faculty of EngineeringMansoura UniversityEgypt UniversitéFrançaise dÉgypte Ismailia Desert RoadEl ShoroukCairoEgypt

In this paper,new four fifth-order fractional nonlinear equations are derived and *** frac-tional terms are defined in the conformable sense and these equations are then solved using two effective methods,namely,the sub-equation and the generalized Kudryashov *** methods were tested on the proposed models and succeeded in finding new solutions with different values of parameters.A graphical representation of some results is provided and proves the efficiency and applicability of the proposed methods for providing solutions with known physical *** methods are good candi-dates for solving other similar problems in the future.

关键词： Conformable derivative Generalized Kudryashov method Sub-equation method Riccati equation Solitons

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Resource allocation of 5G Network by Particle Swarm Optimization and Game Theory

Resource Allocation of 5G Network by Particle Swarm Optimiza...

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作者： Syed waleed 华南理工大学

学位级别：硕士

Given the high use of mobile communications,it is more recommended to deploy cellular networks whose diagrams allow the reintegration of *** 5G,the challenge is to increase the capacity and the throughput for a multitude of radiant base stations（BS）at minimum power in an urban ***,the coefficient（ICI）caused by the spectral overlap between base *** decreases network capacity,causing serious problems in the performance of User Equipment（UE）.Multiuser OFDMA networks include LTE/LTE-A networks and dense small-scale cell networks,the issues regarding the assignment of resource and power control discussed in this *** contribution of this thesis derived into the following two parts: In the first part,we propose the resource allocation algorithm based on particle swarm optimization（PSO）in the 5G *** minimize the computation costs,an objective function is formulated with some constraints,which denote the users’ Qo S requirements and *** solving the issue regarding composite nonlinear optimization,a unique population-built search algorithm is employed is referred to as the PSO.A PSO algorithm is presented to search the maximum allocation in each cell and corresponding resource *** the second part,we propose the power control of the 5G network based on Game theory（GT）.The GT,used for power control optimization of the 5G *** issue of power allotment is resolved by employing a decentralized GT procedure and the requirement of signaling messages interchange among distinct cells is *** resource and power are assigned to the group of nearby cells *** required information is received from the cells in the neighborhood after which the transmission power is altered to achieve the desired *** power control,a nondeterministic method called the stochastic algorithm can also be *** algorithm simulated for a total of 10 base stations in three ***,the results for GT are c

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Expansive Soil Stabilization by Bagasse Ash in Partial Replacement of Cement

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Journal of Renewable Materials 2023年第4期11卷 1911-1935页

作者： waleed Awadalseed Honghua Zhao Hemei Sun Ming Huang Cong Liu State Key Laboratory of Structural Analysis for Industrial Equipment Department of Engineering MechanicsDalian University of TechnologyDalian116023China State Key Laboratory of Structural Analysis for Industrial Equipment Department of Engineering MechanicsInternational Research Center for Computational MechanicsDalian University of TechnologyDalian116023China Department of Geotechnical Engineering College of Civil EngineeringHunan UniversityChangsha410082China College of Civil Engineering Fuzhou UniversityFuzhou350116China

This study examined the effects of using bagasse ash in replacement of ordinary Portland cement(OPC)in the treatment of expansive *** study concentrated on the compaction characteristics,volume change,compressive strength,splitting tensile strength,microstructure,California bearing ratio(CBR)value,and shear wave velocity of expansive soils treated with *** bagasse ash replacement ratios were used to create soil *** varying curing times of 7,14,and 28 days,standard compaction tests,unconfined compressive strength tests,CBR tests,Brazilian split tensile testing,and bender element(BE)tests were carried *** to X-ray diffraction(XRD)investigations,quartz and crystobalite make up the majority of the minerals in bagasse *** ash contains a variety of grain sizes,including numerous fiber-shaped particles,according to a scanning electronic microscope(SEM)*** all of the treated specimens with various replacement ratios,the overall additive content has not *** results of the Brazilian split tensile tests demonstrate improved tensile strength for all specimens with various replacement proportions.A lower maximum dry density and a greater optimal water content would result from the substitution of bagasse *** the replacement ratio is not more than 20%,the CBR values of the parts replaced specimens are even higher than the cement *** results of BE testing on the treated soils show that there is significant stiffness anisotropy but that it steadily diminishes with curing time and replacement *** to the study,bagasse ash is a useful mineral additive,and the best replacement ratio(CBA20)is 20%.

关键词： Expansive soil bagasse ash cement calcium silicate hydrate(CSH) stiffness anisotropy

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In vitro inhibitory analysis of consensus siRNAs against NS3 gene of hepatitis C virus 1a genotype

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Asian Pacific Journal of Tropical Medicine 2017年第7期10卷 763-770页

作者： Imran Shahid waleed Hassan al Malki Mohammed Wanees al Rabia Mohammed Hasan Mukhtar Shaia Saleh R.almalki Saad Ahmed alkahtani Sami S.Ashgar Hani S.Faidah Muhammad Hassan Hafeez Department of Pharmacology and Toxicology College of PharmacyUmm Al Qura University Department of Medical Microbiology College of MedicineKing Abdul Aziz University Department of Biochemistry Faculty of MedicineUmm Al Qura University Department of Laboratory Medicine Faculty of Applied Medical SciencesAlbaha University College of Pharmacy Najran University Department of Microbiology College of MedicineUmm Al Qura University Department of Gastroenterology and Hepatology Fatima Memorial College of Medicine and Dentistry

Objective: To explore inhibitory effects of genome-specific, chemically synthesized siRNAs(small interference RNA) against NS3 gene of hepatitis C virus(HCV) 1a genotype in stable Huh-7(human hepatoma) cells as well as against viral replication in serum-inoculated Huh-7 cells. Methods: Stable Huh-7 cells persistently expressing NS3 gene were produced under antibiotic gentamycin(G418) selection. The cell clones resistant to 1 000 μg antibiotic concentration(G418) were picked as stable cell clones. The NS3 gene expression in stable cell clone was confirmed by RT-PCR and Western blotting. siRNA cell cytotoxicity was determined by MTT cell proliferation assay. Stable cell lines were transfected with sequence specific siRNAs and their inhibitory effects were determined by RT-PCR, real-time PCR and Western blotting. The viral replication inhibition by siRNAs in serum inoculated Huh-7 cells was determined by real-time PCR. Results: RT-PCR and Western blot analysis confirmed NS3 gene and protein expression in stable cell lines on day 10, 20 and 30 post transfection. MTT cell proliferation assay revealed that at most concentrated dose tested(50 nmol/L), siRNA had no cytotoxic effects on Huh-7 cells and cell proliferation remained unaffected. As demonstrated by the siRNA time-dependent inhibitory analysis, siRNA NS3-is44 showed maximum inhibition of NS3 gene in stable Huh-7 cell clones at 24(80%, P=0.013) and 48 h(75%, P=0.002) post transfection. The impact of siRNAs on virus replication in serum inoculated Huh-7 cells also demonstrated significant decrease in viral copy number, where siRNA NS3-is44 exhibited 70%(Pal RNA reduction as compared to NS3-is33, which showed a 64%(Pal copy number. siRNA synergism(NS3-is33 + NS3-is44) decreased viral load by 84%(Pal inhibition by each siRNA(i.e., 64%–70%(P<0.05) in serum-inoculated cells. Synthetic siRNAs mixture(NS5Bis88 + NS3-is33) targeting different region of HCV genom

关键词： Hepatitis C virus NS3 protein Stable Huh-7 cell culture system RNA interference NS5B HCV therapeutics

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Paroxetine Augments while Naloxone Abolishes the Analgesic Effect of Paracetamol in Acute Nociceptive Pain in Mice

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Pharmacology & Pharmacy 2013年第4期4卷 398-405页

作者： Mohammad Raafat Abdalla waleed al Malki Muhammad Ahmed Department of Pharmacology and Toxicology Faculty of Pharmacy Umm Al-Qura University Makkah KSA

The mechanism(s) of analgesic action of paracetamol (acetaminophen;N-acetyl-p-aminophenol) remains controversial. Previous studies on rats suggested that the antinociceptive action of paracetamol might involve the central descending inhibitory pain pathways recruiting both a serotoninergic and an opioidergic system. This study explores this issue in mice using paroxetine, the most potent selective serotonin re-uptake inhibitor, and the nonselective opioid pure antagonist naloxone. Animals were divided into two main groups for two separate experiments, each subdivided into 3 subgroups. In both experiments;the first group served as control, the second group received paracetamol (200 mg/kg, i.p). In one experiment, the third group received paroxetine (20 mg/kg p.o for 7 days) before paracetamol. In the other experiment, animals of the third group were pretreated with naloxone (5 mg/kg, i.p) 30 min before paracetamol. The antinociceptive effect of paracetamol was tested using the hot plate test. Paracetamol displayed a significant antinociceptive activity that was augmented by pretreatment with paroxetine as was shown by maintenance of its effect beyond that shown by paracetamol alone. On the other hand, pretreatment with naloxone abolished paracetamol’s antinociceptive activity in the hot-plate test. These results extended the previous observation in rats that the antinociceptive effect of paracetamol involved activation of a central descending pain inhibitory pathway with serotonin and opioidergic peptides being potential mediators recruited.

关键词： Paracetamol Paroxetine Naloxone Mice

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