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The Impact of Blood Transfusion on the Efficiency of Stem Cell Transplants

Case Reports in Clinical Medicine 2024年第8期13卷 328-338页

作者： Amer Saud AL-Humaidan Saleh Saud Almutairi Mohammed Hussain Khubrani Raffah Mahdi Bajudah waleed mohammad alzabidi Mohammed Hafiz Almasabi Bader Mohammed Saleh Alhomaid Waad Ali Alshehri Wejdan Saleh Alghamdi Raghad Abdullah Alwthinani Department of Pathology and Laboratory King Abdulaziz Medical City Ministry of National Guard Health Affairs Riyadh Saudi Arabia

Background: While blood product transfusion is essential for managing hematologic deficits in Allogenic Hematopoietic stem cell transplant (AHSCT) recipients, it has risks including infectious disease transmission, alloimmunization, and transfusion reactions. These risks have sparked an ongoing debate regarding the overall impact of transfusions on patient outcomes. Thus, this study aimed to evaluate the impact of Red Blood Cells (RBCs) and/or platelet transfusion on the infection incidence and overall survival in AHSCT patients. Methods: We performed a retrospective analysis of clinical and laboratory data of sixty adult patients with primary malignant hematological disorder who had undergone AHSCT. Participants’ data were categorized into two groups;Group 1 (low transfusion group) consisted of patients receiving 10 units. Quantitative data were expressed as mean ± SD. The t-test of significance and Chi-square (χ2) test were used, with p ≤ 0.05 considered significant. Result: A total of 60 patients’ data was included. In Group 1, out of 30 patients, 13 (43.33%) developed infections. In contrast, Group 2 had 21 (70%) out of 30 patients develop infections. Group 1 had a higher survival rate (57.8%) than Group 2 (transfusion > 10 units) (46.2%) with a chi-square value = 23.56, and p-value Conclusion: The volume of blood product transfusions has a considerable impact on patient outcomes, particularly infection and survival rates. Additional long-term prospective studies and larger randomized controlled trials are needed to strengthen the evidence for determining transfusion protocols for these patients.

关键词： Hematologic Neoplasms Hematopoietic Stem Cell Transplantation Blood Transfusion Survival Rate

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Performance Comparison of Hyper-V and KVM for Cryptographic Tasks in Cloud Computing

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Computers, Materials & Continua 2024年第2期78卷 2023-2045页

作者： Nader Abdel Karim Osama A.Khashan waleed K.Abdulraheem Moutaz Alazab Hasan Kanaker Mahmoud E.Farfoura mohammad Alshinwan Department of Intelligent Systems Faculty of Artificial IntelligenceAl-Balqa Applied UniversityAl-Salt1705Jordan Research and Innovation Centers Rabdan AcademyP.O.Box 114646Abu DhabiUnited Arab Emirates Department of Information Systems and Networks TheWorld Islamic Sciences and Education UniversityAmman11947Jordan Department of Cyber Security Isra UniversityAmman1162Jordan Faculty of Science and Information Technology Al-Zaytoonah University of JordanAmman11733Jordan Middle East University Research Unit Middle East UniversityAmman11831Jordan

As the extensive use of cloud computing raises questions about the security of any personal data stored there,cryptography is being used more frequently as a security tool to protect data confidentiality and privacy in the cloud environment.A hypervisor is a virtualization software used in cloud hosting to divide and allocate resources on various pieces of *** choice of hypervisor can significantly impact the performance of cryptographic operations in the cloud *** important issue that must be carefully examined is that no hypervisor is completely superior in terms of performance;Each hypervisor should be examined to meet specific *** main objective of this study is to provide accurate results to compare the performance of Hyper-V and Kernel-based Virtual Machine(KVM)while implementing different cryptographic algorithms to guide cloud service providers and end users in choosing the most suitable hypervisor for their cryptographic *** study evaluated the efficiency of two hypervisors,Hyper-V and KVM,in implementing six cryptographic algorithms:Rivest,Shamir,Adleman(RSA),Advanced Encryption Standard(AES),Triple Data Encryption Standard(TripleDES),Carlisle Adams and Stafford Tavares(CAST-128),BLOWFISH,and *** study’s findings show that KVM outperforms Hyper-V,with 12.2%less Central Processing Unit(CPU)use and 12.95%less time overall for encryption and decryption operations with various file *** study’s findings emphasize how crucial it is to pick a hypervisor that is appropriate for cryptographic needs in a cloud environment,which could assist both cloud service providers and end *** research may focus more on how various hypervisors perform while handling cryptographic workloads.

关键词： Cloud computing performance virtualization hypervisors Hyper-V KVM cryptographic algorithm

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Improving Prediction Efficiency of Machine Learning Models for Cardiovascular Disease in IoST-Based Systems through Hyperparameter Optimization

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Computers, Materials & Continua 2024年第9期80卷 3485-3506页

作者： Tajim Md.Niamat Ullah Akhund waleed M.Al-Nuwaiser Department of Computer Science and Engineering(CSE) Daffodil International UniversityDhaka1216Bangladesh Graduate School of Science and Engineering Saga UniversitySaga8408502Japan Computer Science Department College of Computer and Information SciencesImam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11623Saudi Arabia

This study explores the impact of hyperparameter optimization on machine learning models for predicting cardiovascular disease using data from an IoST(Internet of Sensing Things)*** distinct machine learning approaches were implemented and systematically evaluated before and after hyperparameter *** improvements were observed across various models,with SVM and Neural Networks consistently showing enhanced performance metrics such as F1-Score,recall,and *** study underscores the critical role of tailored hyperparameter tuning in optimizing these models,revealing diverse outcomes among *** Trees and Random Forests exhibited stable performance throughout the *** enhancing accuracy,hyperparameter optimization also led to increased execution *** representations and comprehensive results support the findings,confirming the hypothesis that optimizing parameters can effectively enhance predictive capabilities in cardiovascular *** research contributes to advancing the understanding and application of machine learning in healthcare,particularly in improving predictive accuracy for cardiovascular disease management and intervention strategies.

关键词： Internet of sensing things(IoST) machine learning hyperparameter optimization cardiovascular disease prediction execution time analysis performance analysis wilcoxon signed-rank test

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Isolation of aerobic bacteria from ticks infested sheep in Iraq

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Asian Pacific Journal of Tropical Biomedicine 2016年第1期6卷 67-70页

作者： waleed Ibrahem Jalil mohammad Mushgil Zenad Department of Veterinary Internal and Preventive Medicine College of Veterinary Medicine University of Diyala Department of Veterinary Internal and Preventive Medicine College of Veterinary Medicine University of Baghdad

Objective:To highlight the presence of aerobic bacteria in live ticks infested sheep,in Diyala Governorate,***:One hundred and thirty adult alive ticks were picked up from sheep which were reared in different farms in Diyala Governorate,Iraq,during the period from November 2012 to May *** were classified in the Natural History Museum in *** were dissected aseptically for extraction of the salivary gland and *** removed tissue from each organ was inoculated in buffer peptone water(1%)and incubated for 2 h at 37 °C,to maintain weak and/or injured bacterial cells,then transmitted to nutrient broth incubated at 37 °C for 18 *** was done on three solid bacteriological media(nutrient,blood and McConkey agars),and then incubated at37 ℃ for 24 *** identification was performed by using multiple biochemical tests and API-20 *** were analyzed by using Statistical Analysis System version 9.1,***-square test was used for comparison at significant level of P ≤ ***:Two species of ticks were identified[Rhipicephalus(Boophilus) annulatus and Hyalomma turanicum].High bacterial isolation rate was observed(483 isolates).A significant high isolation rate was recorded from Rhipicephalus annulatus(63.14%).Six bacterial species were identified[Escherichia coli(28.36%),Pseudomonas aeruginosa(18.01%),Bacillus cereus(14.69%),Staphylococcus aureus(13.66%),Citrobacter freundii(13.04%),and Enterobacter species(12.21%)].Also the high bacterial isolation rates were recorded in the temperate months(November,March and April);these coincided with high reproductive performance of ***:The high isolation rate of aerobic pathogens from ticks might reflect the active contribution of this arthropod in environmental contamination and increase the probability of transmitting bacterial pathogens to their hosts.

关键词： Ticks Aerobic bacteria Sheep Iraq

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Remote ischemic conditioning approach for the treatment of ischemic stroke

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Neural Regeneration Research 2020年第6期15卷 1033-1034页

作者： Seyed mohammad Seyedsaadat David F.Kallmes waleed Brinjikji Department of Radiology Mayo Clinic

Stroke is the leading cause of disability and death in North *** has been growing interest in identifying neuroprotective strategies to reduce ischemic burden in patients with acute ischemic ***,despite extensive clinical trials,no neuroprotective agent has been found for prevention of ischemic *** ischemic preconditioning(RIC)is a promising non-invasive strategy that has been proven to provide renal and cardioprotection and has recently found to have a potential broad application in the treatment of neurovascular disease,which has bee linked to its possible effects on the release and activation of endogenous neuroprotective substances against the ischemia/reperfusion injuries in experimental *** endogenous neuroprotection might vaccinate neural tissues against effects of acute IR following primary infarction *** of the method of RIC administration,through manual or automated blood pressure cuff,RIC procedure is inexpensive and easy to *** on the experimental and clinical data,application of RIC avoids possible adverse effects and interactions associated with chemical pharmacological *** previous clinical studies RIC was safe and associated with only minor transient adverse effects in few cases,including petechia and minor limb pain,which were mostly resolved shortly after completing the treatment.

关键词： prevention treatment Remote

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Intention to Use Mobile Augmented Reality in the Tourism Sector

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Computer Systems Science & Engineering 2021年第5期37卷 187-202页

作者： Malik Khlaif Gharaibeh Natheer Khlaif Gharaibeh mohammad Ayoub Khan waleed Abdel karim Abu-ain Musab Kasim Alqudah Faculty of Business Jadara UniversityIrbid21110Jordan College of Computer Science&Engineering at Yanbu Taibah UniversityYanbu41911Saudi Arabia College of Computing and Information Technology University of BishaBisha67714Saudi Arabia College of Community Taibah UniversityBadr46354Saudi Arabia

This article examines the main variables that influence the intention to use Augmented Reality(AR)applications in the tourism sector in *** study model has been constructed based on the unified theory of acceptance and the use of technology2(UTAUT2),by incorporating a new construct(aesthetics)to explore the usage intention of Mobile Augmented Reality in Tourism(MART).A questionnaire was used and distributed to a sample of 450 *** were analyzed using the Smart PLS version *** testing 12 hypotheses.29 measurement items were carefully reviewed based on previous studies that were selected to assess the research *** findings revealed that the proposed model elucidates 35.7%of the variance in the users’intention to use *** results also showed that both performance expectancy and aesthetics were found to be the most significant factors at level(0.001).Four variables,respectively,were at level(0.01)which consisted of social influence,facilitating conditions,hedonic motivation,and price *** weakest effect was effort expectancy at level(0.05).As the use of AR has become important for tourists,this study establishes a research base that can be built upon for future *** developers can benefit from the results of this research to design and deliver this service successfully and to ensure that its adoption by users is achieved.

关键词： Intention to use UTAUT2 aesthetics performance expectancy augmented reality social influence effort expectancy MART AR

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Performance improvement of solution-processed CdS/CdTe solar cells with a thin compact TiO_2 buffer layer

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Science Bulletin 2016年第1期61卷 86-91页

作者： Aashir waleed Qianpeng Zhang mohammad Mahdi Tavakoli Siu-Fung Leung Leilei Gu Jin He Xiaoliang Mo Zhiyong Fan Department of Electronic and Computer Engineering The Hong Kong University of Science and Technology Peking University Shenzhen SOC Key Laboratory PKUHKUST Shenzhen-Hongkong Instituition Department of Materials Science Fudan University

The device performance of CdS/CdTe solar cells largely depends on not only the back ohmic contact, but also the conformality of Cd S window layer coating. In order to reduce the light absorption loss in Cd S, the Cd S thickness is usually less than 100 nm. However, pinholes in Cd S and non-conformal coverage of Cd S on transparent conducting oxide layer will cause shunting thus leading to device performance degradation and failure. In this paper, low-temperature and low-cost fabrication methods, i.e., chemical bath deposition and electrochemical deposition, were used to deposit Cd S and Cd Te, respectively. It was found that the yield of device was around 20 % due to shunting. In order to alleviate this problem, a compact layer of TiO2 was inserted between the fluorine-doped tin oxide and Cd S as a buffer layer. The thickness effect of TiO2 was studied and showed that devices with thin(20 nm thickness) TiO2 performed better than the counterparts with thick layers. It was discovered that device yield improved to 80 % and stability in air substantially improved with TiO2 layer.

关键词： Thin films Titanium dioxide Solarenergy Cadmium compounds

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Age and Gender Classification Using Backpropagation and Bagging Algorithms

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Computers, Materials & Continua 2023年第2期74卷 3045-3062页

作者： Ammar Almomani Mohammed Alweshah waleed Alomoush mohammad Alauthman Aseel Jabai Anwar Abbass Ghufran Hamad Meral Abdalla Brij B.Gupta Research and Innovation Department Skyline University CollegeP.O.Box 1797SharjahUAE IT-department-Al-Huson University College Al-Balqa Applied UniversityP.O.Box 50IrbidJordan Prince Abdullah Ben Ghazi Faculty of Information and Communication Technology Al-Balqa Applied UniversityAl-SaltJordan School of Information Technology Skyline University CollegeSharjah P.O.Box 1797United Arab Emirates Department of Information Security Faculty of Information TechnologyUniversity of PetraAmmanJordan Department of Computer Science and Information Engineering Asia UniversityTaizhongTaiwan Department of Computer Science King Abdulaziz UniversityJeddahSaudi Arabia

Voice classification is important in creating more intelligent systems that help with student exams,identifying criminals,and security *** main aim of the research is to develop a system able to predicate and classify gender,age,and ***,a newsystem calledClassifyingVoice Gender,Age,and Accent(CVGAA)is *** and bagging algorithms are designed to improve voice recognition systems that incorporate sensory voice features such as rhythm-based features used to train the device to distinguish between the two gender *** has high precision compared to other algorithms used in this problem,as the adaptive backpropagation algorithm had an accuracy of 98%and the Bagging algorithm had an accuracy of 98.10%in the gender identification *** has the best accuracy among all algorithms,with 55.39%accuracy in the voice common dataset and age classification and accent accuracy in a speech accent of 78.94%.

关键词： Classify voice gender accent age bagging algorithms back propagation algorithms AI classifiers

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A study of in vitro antibacterial activity of lanthanides complexes with a tetradentate Schiff base ligand

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Asian Pacific Journal of Tropical Biomedicine 2013年第5期3卷 367-370页

作者： waleed Mahmoud Al Momani Ziyad Ahmed Taha Abdulaziz Mahmoud Ajlouni Qasem mohammad Abu Shaqra Muaz Al Zouby Department of Allied Medical Sciences Al Balqa' Applied University Department of Applied Chemical Sciences Jordan University of Science and Technology Medical Diagnostic Laboratories

Objective:To establish the antibacterial activity of lanthanides complexes with a tetradentate Schiff base ligand ***:(N,N'-bis(l-naphthaldimine)-o-phenylenediamine)was prepared from the condensation of 2—hydroxy-1-naphthaldehyde with o-phenylenediamine in a molar ratio of 2:*** antimicrobial activity of the resultant Ln(Ⅲ)complexes was investigated using agar well diffusion and micro-broth dilution techniques;the latter was used to establish the minimum inhibitory concentrations for each compound ***:Most of Ln(Ⅲ)complexes were found to exhibit antibacterial activities against a number of pathogenic bacteria with MICs ranging between 1.95-250.00μg/*** aureus was the most susceptible bacterial species to[LaL(NO_3)_2(H_2O)](NO_3)complex while Shigella dysenteriae and Escherichia coli required a relatively higher MIC(250μg/mL).Trie complexes La(Ⅲ)and Pr(Ⅲ)were effective inhibitors against Staphylococcus aureus,whereas Sm(Ⅲ)complex was effective against Serratia *** the other hand,Gd(Ⅲ),La(Ⅲ)and Nd(Ⅲ)were found to be more potent inhibitors against Pseudompnas aeruginosa than two of commonly used *** remaining Ln(Ⅲ)complexes showed no remarkable activity as compared to the two standard drugs ***:Tetradentate Schiff base ligand L and its complexes could be a potential antibacterial compounds after further investigation.

关键词： Antimicrobial Biomolecules Organics Synthetic ligands

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Paroxetine Augments while Naloxone Abolishes the Analgesic Effect of Paracetamol in Acute Nociceptive Pain in Mice

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Pharmacology & Pharmacy 2013年第4期4卷 398-405页

作者： mohammad Raafat Abdalla waleed Al Malki Muhammad Ahmed Department of Pharmacology and Toxicology Faculty of Pharmacy Umm Al-Qura University Makkah KSA

The mechanism(s) of analgesic action of paracetamol (acetaminophen;N-acetyl-p-aminophenol) remains controversial. Previous studies on rats suggested that the antinociceptive action of paracetamol might involve the central descending inhibitory pain pathways recruiting both a serotoninergic and an opioidergic system. This study explores this issue in mice using paroxetine, the most potent selective serotonin re-uptake inhibitor, and the nonselective opioid pure antagonist naloxone. Animals were divided into two main groups for two separate experiments, each subdivided into 3 subgroups. In both experiments;the first group served as control, the second group received paracetamol (200 mg/kg, i.p). In one experiment, the third group received paroxetine (20 mg/kg p.o for 7 days) before paracetamol. In the other experiment, animals of the third group were pretreated with naloxone (5 mg/kg, i.p) 30 min before paracetamol. The antinociceptive effect of paracetamol was tested using the hot plate test. Paracetamol displayed a significant antinociceptive activity that was augmented by pretreatment with paroxetine as was shown by maintenance of its effect beyond that shown by paracetamol alone. On the other hand, pretreatment with naloxone abolished paracetamol’s antinociceptive activity in the hot-plate test. These results extended the previous observation in rats that the antinociceptive effect of paracetamol involved activation of a central descending pain inhibitory pathway with serotonin and opioidergic peptides being potential mediators recruited.

关键词： Paracetamol Paroxetine Naloxone Mice

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