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Subrectal and Subcutaneous Wound Infiltration with Bupivacaine versus Pethidine for Post Cesarean Section Pain Relief: Randomized Controlled Trial

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Open Journal of Obstetrics and Gynecology 2018年第11期8卷 1071-1083页

作者： waleed m. Khalaf mohamed Elmandouh mohamed Ibrahim Sarah Safwat Department of Obstetrics and Gynecology Faculty of Medicine Ain Shams University Cairo Egypt

Background: Cesarean section (CS), one of the most common major operative procedures, performed all over the world. Incisional infiltration with local anesthetics is a simple, cheap and effective mean of providing good analgesia for surgical operations without any major side effects & allowing early patients’ mobilization & postoperative recovery, so the purpose of study is to compare between the effect of wound infiltration with bupivacaine versus pethidine for post cesarean section pain relief. Patients and methods: A randomized controlled trial (RCT) was conducted in Ain Shams University maternity hospital in the period from August 2016 and January 2017. 100 full term pregnant females randomized into two groups: Group A (50 patients) Bupivacaine group: Subcutaneous and subrectal infiltration with 10 ml 0.25% Bupivacaine (2.5 mg/ml) diluted in 10 ml normal saline before closure of the wound was done;Group B (50 patients) Pethidine group: Subcutaneous and subrectal infiltration with 1 ml pethidine (50 mg/ml) diluted in 19 ml normal saline before closure of the wound was done. All patients had cesarean section under spinal anesthesia. Study outcome measures post-operative pain scores using visual analogue scale, post-operative analgesia requirement time to first rescue analgesia, onset of mobilization, side effect of local anesthetic, wound infection (after one week). It was registered on clinical *** with ID: NCT03652116. Results: Visual analogue scale values differ significantly between pethidine group and that of bupivacaine at rest and on coughing at 4, 8, 12, 24 hours & analgesic consumption (P value st time request analgesia per minute comparing group A to group B (P value 0.001). There is no significant difference between bupivacaine and pethidine regarding time of ambulation, side effects or complications. Conclusion: Infiltration of the wound of cesarean section with pethidine gives effective analgesia for several hours as compared to Bupivacaine.

关键词： Analgesia Ambulation Wound Infiltration Pethidine Bupivacaine

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Treatment of forearm diaphyseal defect by distraction compression bone transport and continued distraction for radial head reduction:A case study

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Chinese Journal of Traumatology 2019年第5期22卷 304-307页

作者： Nikolay m.Kliushin Paul Stepanenko waleed A.mekki Bone Infection Clinic Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics6M.Ulianovast.Kurgan 640014Russian Federation

Treatment of infected forearm nonunion and defects represents a difficult task for the operating *** methods like composite and vascularized fibular grafts and the induced membranes filled with cancellous autografts or the masquelet technique have been reported to be useful and suc-cessful,but sometimes it is difficult to predict the outcome and cannot address simultaneous deformities or the need to apply gradual distraction for reduction of a chronically dislocated radial *** technique has an answer for such *** report a 43 years old man with infected ulnar defect and dislocated radial head as a result of infected monteggia fracture:the patient was successfully treated by Ilizarov bone transport after failed attempts by bone spacer and fibular graft.

关键词： monteggia's fracture Forearm defects Ilizarov technique Distraction histogenesis Bone transport

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Severity Based Light-Weight Encryption model for Secure medical Information System

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Computers, materials & Continua 2023年第3期74卷 5691-5704页

作者： Firas Abedi Subhi R.m.Zeebaree Zainab Salih Ageed Hayder m.A.Ghanimi Ahmed Alkhayyat mohammed A.m.Sadeeq Sarmad Nozad mahmood Ali S.Abosinnee Zahraa H.Kareem Ali Hashim Abbas waleed Khaild Al-Azzawi mustafa musa Jaber mohammed Dauwed Department of mathematics College of EducationAl-Zahraa University for WomenKarbalaIraq Energy Eng.Department Technical College of EngineeringDuhok Polytechnic UniversityDuhokIraq Computer Science Department College of ScienceNawroz UniversityDuhokIraq Biomedical Engineering Department College of EngineeringUniversity of Warith Al-AnbiyaaKarbalaIraq College of Technical Engineering The Islamic UniversityNajafIraq ITm Department Technical College of AdministrationDuhok Polytechnic UniversityDuhokIraq Computer Technology Engineering College of Engineering TechnologyAl-Kitab UniversityIraq Altoosi University College NajafIraq Department of medical Instrumentation Techniques Engineering Al-Mustaqbal University CollegeHillah51001Iraq College of Information Technology Imam Ja’afar Al-Sadiq UniversityAl-Muthanna66002Iraq Department of medical Instruments Engineering Techniques Al-Farahidi UniversityBagdadIraq Department of medical Instruments Engineering Techniques Al-Turath University CollegeBaghdad10021Iraq Department of medical Instruments Engineering Techniques Al-Farahidi UniversityBaghdad10021Iraq Department of medical Instrumentations Techniques Engineering Dijlah University CollegeBaghdadIraq

As the amount of medical images transmitted over networks and kept on online servers continues to rise,the need to protect those images digitally is becoming increasingly ***,due to the massive amounts of multimedia and medical pictures being exchanged,low computational complexity techniques have been *** commonly used algorithms offer very little security and require a great deal of communication,all of which add to the high processing costs associated with using ***,a deep learning classifier is used to classify records according to the degree of concealment they *** images that aren’t needed can be saved by using this method,which cuts down on security *** is one of the most effective methods for protecting medical images after this *** and dispersion are two fundamental encryption processes.A new encryption algorithm for very sensitive data is developed in this *** splitting with image blocks is nowdeveloped by using Zigzag patterns,rotation of the image blocks,and random permutation for scrambling the *** that,this research suggests a Region of Interest(ROI)technique based on selective picture *** the first step,we use an active contour picture segmentation to separate the ROI from the Region of Background(ROB).Permutation and diffusion are then carried out using a Hilbert curve and a Skew Tent *** all of the blocks have been encrypted,they are combined to create encrypted *** investigational analysis is carried out to test the competence of the projected ideal with existing techniques.

关键词： Deep learning encryption medical images scrambling security skew tent map rotation zigzag pattern

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Two Very Accurate and Efficient methods for Solving Time-Dependent Problems

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Applied mathematics 2018年第11期9卷 1270-1280页

作者： mohamed El-Gamel waleed Adel m. S. El-Azab Department of mathematical Sciences Faculty of Engineering Mansoura University Mansoura Egypt

In this paper, collocation method based on Bernoulli and Galerkin method based on wavelet are proposed for solving nonhomogeneous heat and wave equations. The two methods have the linear systems solved by suitable sol... 详细信息

关键词： Wavelet Galerkin Daubechies Bernoulli Collocation

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Effect of metformin on Endometrial Thickness and Subendometrial Flow Patterns in Anovulatory Patients with Polycystic Ovarian Syndrome

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Open Journal of Obstetrics and Gynecology 2018年第14期8卷 1465-1475页

作者： waleed m. Khalaf Sherif A. Akl Rania R. Ramadan Obstetrics and Gynecology Department Faculty of Medicine Ain Shams University Cairo Egypt misr University for Sciences and Technology Giza Egypt

Background: Polycystic ovarian syndrome (PCOS) is considered the commonest endocrinological disorder affecting reproductive aged women. PCOS compromises fertility through various pathways. These pathways include hyperandrogenism, insulin resistance and impedance of the uterine and endometrial blood flow. metformin improves the blood flow to the endometrium. It acts by reducing androgen level and correction of insulin resistance. Endometrial vascular indices were evaluated in this study to evaluate endometrial receptivity in anovulatory patients with PCOS. Aim of the Work: To evaluate the outcome of metformin administration in anovulatory patients with PCOS and its effect on the endometrium. This included its role in ovulation and improvement of pregnancy rates. Patients and methods: This study included 85 patients from Ain Shams University outpatient infertility clinics from 1st of January, 2018 till 30th of June, 2018. We investigated these patients before treatment with ultrasound on day 14, 21. We evaluated endometrial thickness, uterine artery flow pattern, endometrial and subendometrial flow patterns. The patients received metformin 500 mg three times per day for three months. After this duration, we reevaluated them by ultrasound at days 14, 21. Results: metformin therapy resulted in a significant increase of endometrial thickness and had a significant decrease on uterine, endometrial and subendometrial resistance index (R.I) and pulsatility index (P.I) at day 14, 21 compared to pre-treatment values indicating better blood flow. Conclusion: metformin therapy resulted in improvement of endometrial flow patterns. Also, it resulted in increase in endometrial thickness and improvement of uterine artery flow.

关键词： Endometrial Thickness Subendometrial Flow Patterns Anovulatory PCOS metformin

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Computational Aspects of Electromagnetic Fields near H.V. Transmission Lines

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Energy and Power Engineering 2009年第2期1卷 65-71页

作者： Ossama E. GOUDA Ghada m. AmER waleed A. SALEm 不详

Biological effects of electromagnetic fields on the human body, animals and plants have been a subject of scientific interest and public concern for their risk on the living organisms such as blood leukemia and others. The high voltage transmission and distribution lines, which pass beside some houses, factories and schools are source of electromagnetic fields. This paper presents the field calculations around and near of high voltage transmission lines 220 kV and 500kV. To calculate the induced current, the power density, the electric field and the magnetic field of grounded and ungrounded human body cylindrical model are used. mATLAB program package is used for mathematical calculation of the distribution of the EmF in human body under high voltage power transmission lines.

关键词： computational aspects EmF H. V. transmission lines

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Particle-mediated Histotripsy for the Targeted Treatment of Intraluminal Biofilms in Catheter-Based medical Devices

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Biomedical Engineering Frontiers 2022年第1期3卷 367-380页

作者： Christopher Childers Connor Edsall Isabelle mehochko waleed mustafa Yasemin Yuksel Durmaz Alexander L.Klibanov Jayasimha Rao Eli Vlaisavljevich Virginia Tech Carilion School of medicine USA Department of Biomedical Engineering and mechanics Virginia TechUSA Department of Biomedical Engineering Istanbul Medipol UniversityTurkey Division of Cardiovascular medicine(Department of medicine)and Robert m.Berne Cardiovascular Research Center at University of Virginia School of medicine University of VirginiaUSA Department of medicine Division of Infectious DiseasesVirginia Tech Carilion School of MedicineUSA ICTAS Center for Engineered Health Virginia Polytechnic Institute and State UniversityUSA

*** paper is an initial work towards developing particle-mediated histotripsy(PmH)as a novel method of treating catheter-based medical device(CBmD)intraluminal *** *** commonly become infected with bacterial biofilms leading to medical device failure,infection,and adverse patient *** is a noninvasive focused ultrasound ablation method that was recently proposed as a novel method to remove intraluminal ***,we explore the potential of combining histotripsy with acoustically active particles to develop a PmH approach that can noninvasively remove biofilms without the need for high acoustic pressures or real-time image guidance for *** cavitation thresholds in catheters containing either gas-filled microbubbles(mBs)or fluid-filled nanocones(NCs)were *** ability of these particles to sustain cavitation over multiple ultrasound pulses was tested after a series of histotripsy ***,the ability of PmH to generate selective intraluminal cavitation without generating extraluminal cavitation was ***,the biofilm ablation and bactericidal capabilities of PmH were tested using both mBs and *** significantly reduced the histotripsy cavitation threshold,allowing for selective luminal cavitation for both mBs and *** further showed PmH successfully removed intraluminal biofilms in Tygon ***,results from bactericidal experiments showed minimal reduction in bacteria *** results of this study demonstrate the potential for PmH to provide a new modality for removing bacterial biofilms from CBmDs and suggest that additional work is warranted to develop histotripsy and PmH for treatment of CBmD intraluminal biofilms.

关键词： cavitation remove filled

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Sudden death in the southern region of Saudi Arabia:A retrospective study

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World Journal of Clinical Cases 2023年第20期11卷 4843-4851页

作者： Ahmed mohamed Ahmed Al-Emam.abdulrahman Dajam mohammed Alrajhi waleed Alfaifi mubarak Al-Shraim Ahmed mohamed Helaly Department of Pathology College of MedicineKing Khalid UniversityAsir 61421Saudi Arabia Forensic medicine and Clinical Toxicology Mansoura UniversityMansoura 35516Egypt medical School King Khalid UniversityAsir 61421Saudi Arabia Clinical Science Faculty of MedicineYarmouk UniversityIrbid 21163Jordan

BACKGROUND Sudden death is unanticipated,non-violent death taking place within the first 24 h after the onset of *** is a major public health problem ***,the effects of living at moderate altitude on mortality are poorly *** To retrospectively report the frequency and the main causes of sudden deaths in relation to total deaths at Asir Central Hospital,2255 m above sea level,in the southern region of Saudi Arabia over a period of 4 years from 2013 to *** The medical records of 1821 deaths were examined and showed 353 cases(19.4%)of sudden *** The highest incidence of sudden death was among the elderly(51%),whereas,the lowest was among children and adolescents(6.5%).With regard to gender,the incidence of sudden death was higher in males(54.4%)compared to 45.6% in *** this study,we found that the most common direct causes of sudden death were cardiovascular diseases(29.2%),respiratory disease(22.7%),infectious disease(12.2%),cancer(9.4%)and hematological diseases(6.2%).With respect to seasonal variation,the highest incidence was during winter(31.32%)followed by summer(25.8%).CONCLUSION The results of this study will help emergency physicians and health care providers to exercise due care to reduce the incidence of sudden death and raise public awareness about the impact of sudden death.

关键词： Sudden death High altitude Cardiovascular Gender distribution Age Seasonal variation

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Study of Vitamin D Receptor (VDR) Gene Polymorphisms among Egyptian Cohort Patients with Different Stages of Colorectal Cancer

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Journal of Cancer Therapy 2014年第3期5卷 253-263页

作者： mohamed m. Rizk Nermine H. Zakaria waleed G. Elshazely Clinical Pathology Department Faculty of Medicine Alexandria University Alexandria Egypt Colorectal Surgery Department Faculty of Medicine Alexandria University Alexandria Egypt

Colorectal cancer represents the third cancer worldwide. Studies showed thatinsufficient levels of vitamin D may result in colorectal cancer. Genetic variations in genes controlling vitamin D activity would play a role in determining susceptibility to colorectal cancer. Aim of the work: to study the different genotypes of VDR polymorphisms and detect the association between serum levels of 25(OH)VitD and 1,25(OH)2VitD among sample of Egyptian patients with different stages of colorectal cancer. methods: Ninety patients (60 with different stages of colorectal cancer and 30 patients with benign pathology of the colon) together with 30 healthy controls were examined using PCR-RFLP analysis for FokI, ApaI and TaqI polymorphisms. Results: Genotype distribution for ApaI polymorphism showed no statistically significant difference between patients (colorectal cancer and benign) and controls with p = 0.1. There was no statistically significant difference in FokI polymorphism where p = 0.26 and genotype distribution for TaqI was also insignificant with p = 0.016. The median serum level of 25(OH)VitD was low in cancer cases compared to the control group and benign cases with (p 0.001). There was no statisticallysignificant difference of median serum level of 1,25(OH)2VitD between benign and cancer cases. There was statistically significant difference of median serum level of 25(OH)VitD and 1,25(OH)2VitD between stage I and stage II with (p = 0.004) and (p 0.001), and between stage I and stage III with (p = 0.001)and (p 0.001), but no statistically significant difference between stage II and III with (p = 0.514). Conclusions: There is ethnic variability in vitamin D receptor gene polymorphisms. The lack of significant association of the studied gene polymorphism in our population suggests that its association with other functionally known gene polymorphism might have a role in the pathogenesis of colorectal cancer.

关键词： Vitamin D Receptor (VDR) Colorectal Cancer (CRC) PCR-RFLP (Polymorphism)

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Bacterial infections post-living-donor liver transplantation in Egyptian hepatitis C virus-cirrhotic patients: A singlecenter study

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World Journal of Hepatology 2017年第20期9卷 896-904页

作者： mohamed F montasser Nadia A abdelkader Sara m.abdelhakam Hany Dabbous Iman F montasser Yasmine m massoud waleed abdelmoaty Shereen A Saleh mohamed Bahaa Hany Said mahmoud El-meteini Department of Tropical medicine Faculty of Medicine Ain Shams University Department of Internal medicine Faculty of Medicine Ain Shams University Department of Hepatobiliary Surgery Ain Shams Center for Organ Transplant Faculty of Medicine Ain Shams University

AIm To determine risk factors, causative organisms and antimicrobial resistance of bacterial infections following living-donor liver transplantation(LDLT) in cirrhotic *** This prospective study included 45 patients with hepatitis C virus-related end-stage liver disease who underwent LDLT at Ain Shams Center for Organ Transplant, Cairo, Egypt from January 2014 to November 2015. Patients were followed-up for the first 3 mo after LDLT for detection of bacterial infections. All patients were examined for the possible risk factors suggestive of acquiring infection pre-, intra-and post-operatively. Positive cultures based on clinical suspicion and patterns of antimicrobial resistance were identified. RESULTS Thirty-three patients(73.3%) suffered from bacterial infections; 21 of them had a single infection episode, and 12 had repeated infection episodes. Bile was the most common site for both single and repeated episodes of infection(28.6% and 27.8%, respectively). The most common isolated organisms were gramnegative bacteria. Acinetobacter baumannii was the most common organism isolated from both single and repeated infection episodes(19% and 33.3%, respectively), followed by Escherichia coli for repeated infections(11.1%), and Pseudomonas aeruginosa for single infections(19%). Levofloxacin showed high sensitivity against repeated infection episodes(P = 0.03). Klebsiella, Acinetobacter and Pseudomonas were multi-drug resistant(mDR). Pre-transplant hepatocellular carcinoma(HCC) and duration of drain insertion(in days) were independent risk factors for the occurrence of repeated infection episodes(P = 0.024).CONCLUSION mDR gram-negative bacterial infections are common post-LDLT. Pre-transplant HCC and duration of drain insertion were independent risk factors for the occurrence of repeated infection episodes.

关键词： Living-donor liver transplantation Bacterial infection multi-drug resistance Hepatitis C virus Liver cirrhosis

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