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生态系统观视角下的学习分析

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中国远程教育 2020年第4期41卷 1-11,76页

作者： [南非]保罗·普林斯路 [英]莎伦·斯莱德 [约旦]默罕默德·哈利勒肖俊洪(译) 南非大学经济和管理学院英国开放大学挪威卑尔根大学学习科学与技术中心汕头广播电视大学 Distance Education(Taylor&francis)期刊

学习分析自从2011年出现以来,不管是作为一个研究重点还是实践领域,它一直在发展,从某种程度上讲已经成熟了。学习分析不但在增进我们对学生坚持学习和顺利完成学业的了解以及提高我们教学策略的效果等方面有巨大潜能,它还能帮助学生在... 详细信息

学习分析自从2011年出现以来,不管是作为一个研究重点还是实践领域,它一直在发展,从某种程度上讲已经成熟了。学习分析不但在增进我们对学生坚持学习和顺利完成学业的了解以及提高我们教学策略的效果等方面有巨大潜能,它还能帮助学生在更加知情的情况下做出选择。然而,学习分析在多大程度上影响学生学习?它在什么条件下能够充分发挥其潜能?这些问题引起一些关注。我们在这篇概念性文章中提出从生态系统观的角度理解学习分析,或是把它视为某一个生态系统的一部分,或是把它当成一个生态系统,这个系统由各种人为和非人为因素(行动者)组成,包含一系列相互交叉、常常互相依存且又是彼此一部分的变量。鉴于学习分析有提高学习效果的潜能,我们基于学习的社会批判视角提出学习分析的生态系统观。我们从机构和机构以外社会层面的微观、中观和宏观因素出发对学习分析进行阐述。学习分析的生态系统观不认为学生对自己的学习可以免责,而是更加细致入微地了解促成(或妨碍)学习发生的因素(行动者)。

关键词：生态系统学习学习分析社会批判模型学生成功

与干扰素和利巴韦林治疗慢性丙型肝炎相关的克罗恩病

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世界核心医学期刊文摘（胃肠病学分册） 2005年第8期1卷 20-20页

作者： khalil A Lucidarme D Desurmont P 雷小英 Service de Pathologie Digestive Hpital Saint-Philibert115 rue Grand But 59462 Lomme Cedex Fran ce

Digestive side effects associated with interferon and ribavirin in the treatme nt of chronic hepatitis C seem to be non *** far, inflammatory bowel dis eases have only been rarely described in this context. We report two cases of Cr ohn’s disease which occurred a few months after inter- feron and ribavirin treatment for chronic hepatitis C. The first case was a 43 year old man treated for 7 months with a interferon and ribavirin combination f or chronic hepatitis C who experienced colitis related to Crohn’s disease, with the occurrence of articular and cutaneous manifestations. The second case was a 43 year old women treated for 8 months with a pegylated interferon and ribaviri n combination for chronic hepatitis C who developed Crohn’s disease with right ileo-colic topography and severe evolution requiring an ileo-coecal resection because of the failure of medical treatment. The alpha interferon used for its a ntiviral action against hepatitis C virus, has complex immunomodulationeffects w hich could reveal latent Crohn’s disease.

关键词：慢性丙型肝炎克罗恩病治疗应用炎性肠疾病抗病毒病型免疫调节恶性进展

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疣状银屑病:银屑病的一种特殊临床病理变异

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世界核心医学期刊文摘（皮肤病学分册） 2005年第8期1卷 45-45页

作者： khalil f.K. Keehn C.A. Saeed S. Morgan M.B. 罗素菊 Dr.16124 Chastain Road Odessa FL 33556 United States

Psoriasis is capable of presenting in a variety of clinical and pathologic guises including a rarely described variant variably termed hypertrophic or verrucous psoriasis. Herein, we describe the clinical and pathologic attributes of a large series of patients with this unusual variant of psoriasis and distinguish it from other entities in the differential diagnosis. The histopathologic features and clinical and demographic attributes of a series of 12 cases from 12 patients were reviewed by a single dermatopathologist (MM). The 12 patients consisted of 7 males and 5 females with an average age of 61.8 years (males 38- 93 years, females 41- 71 years). Eight of the patients were Caucasian, 3 Hispanic and 1 African- American. Six of the lesions were located on the knees, 4 involved the elbows, and 2 were seen on the dorsum of the hands (metacarpal- phalangeal joint). The clinical appearance of the lesions consisted of flesh- toned to white mammillated plaques (8 cases) and coalesced papules (4 cases). Each of the biopsies showed regular psoriasiform epidermal hyperplasia with acanthosis, hyperkeratosis, and either spongiform neutrophilic or Munro micro- abscesses. In addition, each showed papillomatosis with bowing of the peripheral rete ridges toward the center of the lesion (buttressing). At high power, epidermal neutrophils were seen in particular surmounting the tips of the suprapapillary plates with accompanying serum. Hypergranulosis and koilocytic change were not observed in any of the lesions. Human papilloma virus (HPV) immunostaining and periodic acid Schiff (PAS) special staining for fungi were negative. Verrucous psoriasis is a distinctive variant of psoriasis with overlapping clinical and pathologic features that might prompt consideration of verruca vulgaris. The presence of epidermal papillomatosis and epidermal buttressing seen in these lesions is reminiscent of the histologic features of verruca vulgaris. Similarly, the presence of coalesced papules m

关键词：疣状银屑病寻常疣表皮突乳头瘤样增生海绵状脓疱皮损周围病理学特点角化过度皮肤病理学高加索人