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Understa.ding the Novel a.proa.h of Na.oferroptosis for Ca.cer Thera.y

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Na.o-Micro Letters 2024年第9期16卷 501-556页

作者： a.sa.a.Sheikh Pra.ha.t Kesha.wa.i waleed H.a.ma.ki salem Sa.ma. a.mujri Linxin Da. Zhe‑Sheng Chen a.irhossein Sa.ebka. Fei Ga. Depa.tment of Pha.ma.eutics School of Pharmaceutical Education and ResearchJamia HamdardNew Delhi 110062India Depa.tment of Pha.ma.ology a.d Toxicology Faculty of PharmacyUmm Al-Qura UniversityMakkahSaudi Arabia Depa.tment of Pha.ma.ology College of PharmacyKing Khalid University61421 Asir‑AbhaSaudi Arabia Sta.e Key La.ora.ory of Southwestern Chinese Medicine Resources Pharmacy SchoolChengdu University of Traditional Chinese MedicineChengdu 611130People’s Republic of China Depa.tment of Pha.ma.eutica. Sciences College of Pharmacy and Health SciencesSt.John’s UniversityNew York 11439USA Biotechnology Resea.ch Center Pharmaceutical Technology InstituteMashhad University of Medical SciencesMashhadIran a.plied Biomedica. Resea.ch Center Mashhad University of Medical SciencesMashhadIran

a. a.new form of regula.ed cell dea.h,ferroptosis ha. unra.eled the unsolicited theory of intrinsic a.optosis resista.ce by ca.cer *** molecula. mecha.ism of ferroptosis depends on the induction of oxida.ive stress through excessive rea.tive oxygen species a.cumula.ion a.d gluta.hione depletion to da.a.e the structura. integrity of *** to their high loa.ing a.d structura. tuna.ility,na.oca.riers ca. escort the delivery of ferro-thera.eutics to the desired site through enha.ced permea.ion or retention effect or by a.tive *** review shed light on the necessity of iron in ca.cer cell growth a.d the fa.cina.ing fea.ures of ferroptosis in regula.ing the cell cycle a.d ***,we discussed the effect of ferroptosis-media.ed thera.y using na.opla.forms a.d their chemica. ba.is in overcoming the ba.riers to ca.cer thera.y.

关键词： Ferroptosis Na.opa.ticles Ferrothera.y Ca.cer Genes Na.otechnology Toxicity Rea.tive oxygen species

a.a.ta.ility of bipedicled sca.p a.va.cement fla. for covera.e of huge sca.p defects a.ter tumor resection

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Chinese Journa. of Pla.tic a.d Reconstructive Surgery 2024年第1期6卷 16-21页

作者： waleed a.da.a.ny Depa.tment of Pla.tic Surgery Faculty of MedicineFayoum UniversityFayoumEgypt

Ba.kground:Severa. reconstructive techniques ha.e been used to reconstruct sca.p *** resea.chers ha.e studied the utiliza.ion of bipedicled sca.p a.va.cement fla.s for sca.p defect *** this study,we will a.sess the a.a.ta.ility of a.bipedicled sca.p a.va.cement fla. for covera.e of huge sca.p defects a.ter tumor ***:This study wa. performed a. the Pla.tic Surgery Depa.tment,Fa.oum University Hospita.,on 20 pa.ients with huge sca.p tumors trea.ed by a.equa.e excision a.d reconstructed using a.bipedicled sca.p a.va.cement fla. from December 2021 to July ***:The study wa. conducted on 20 pa.ients:16(80%)were men a.d 4(20%)were women presenting with la.ge sca.p *** mea. a.e wa. 57.4 yea.s(33-68 yea.s).The sites of the tumors were 10(50%)occipita.,6(30%)pa.ieta.,a.d 4(20%)*** ma.or complica.ions occurred postopera.ively,a.d the bipedicled fla.s survived well in a.l ca.es,with no ***:Huge sca.p defects a.ter tumor resection ca. be sa.ely reconstructed with a.la.ge versa.ile bipedicled a.va.cement sca.p fla.,either tra.sversely or longitudina.ly oriented,with fa.ora.le functiona. results a.d a.cepted a.sthetic results,a.a.t from the a.opecic a.ea.over the gra.ted donor site,which ca. be trea.ed by tissue expa.sion if desired la.er.

关键词： Bipedicled a.va.cement fla. Huge sca.p defects Tumor resection

Sma.t prediction of liquefa.tion-induced la.era. sprea.ing

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Journa. of Rock Mecha.ics a.d Geotechnica. Engineering 2024年第6期16卷 2310-2325页

作者： Muha.ma. Nouma. a.ja. Ra.a.Ta.ek a.doun waleed El-Sekelly New York University(NYU)a.u Dha.i Abu Dhabi129188United Arab Emirates University of Ma.a.ement a.d Technology Lahore54372Pakistan Depa.tment of Civil a.d Environmenta. Eng. Rensselaer Polytechnic Institute(RPI)1108th StreetJEC 4049TroyNY12180USA Depa.tment of Structura. Engineering Mansoura UniversityMansoura35516Egypt

The prediction of liquefa.tion-induced la.era. sprea.ing/displa.ement(Dh)is a.cha.lenging ta.k for civil/geotechnica. *** this study,a.new a.proa.h is proposed to predict Dh using gene expression progra.ming(GEP).Ba.ed on sta.istica. rea.oning,individua. models were developed for two topogra.hies:free-fa.e a.d gently sloping *** with a.compa.ison with conventiona. a.proa.hes for predicting the Dh,four a.ditiona. regression-ba.ed soft computing models,*** process regression(GPR),releva.ce vector ma.hine(RVM),sequentia. minima. optimiza.ion regression(SMOR),a.d M5-tree,were developed a.d compa.ed with the GEP *** results indica.e tha. the GEP models predict Dh with less bia.,a. evidenced by the root mea. squa.e error(RMSE)a.d mea. a.solute error(Ma.)for tra.ning(i.e.1.092 a.d 0.815;a.d 0.643 a.d 0.526)a.d for testing(i.e.0.89 a.d 0.705;a.d 0.773 a.d 0.573)in free-fa.e a.d gently sloping ground topogra.hies,*** overa.l performa.ce for the free-fa.e topology wa. ra.ked a. follows:GEP>RVM>M5-tree>GPR>SMOR,with a.tota. score of 40,32,24,15,a.d 10,*** the gently sloping condition,the performa.ce wa. ra.ked a. follows:GEP>RVM>GPR>M5-tree>SMOR with a.tota. score of 40,32,21,19,a.d 8,***,the results of the sensitivity a.a.ysis showed tha. for both free-fa.e a.d gently sloping ground,the liquefia.le la.er thickness(T_(15))wa. the ma.or pa.a.eter with percenta.e deteriora.ion(%D)va.ue of 99.15 a.d 90.72,respectively.

关键词： La.era. sprea.ing Intelligent modeling Gene expression progra.ming(GEP) Closed-form solution Fea.ure importa.ce

New solutions for four novel genera.ized nonlinea. fra.tiona. fifth-order equa.ions

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Journa. of Ocea. Engineering a.d Science 2024年第1期9卷 59-65页

作者： Mehmet Senol La.re a.inyemi Henrietta.Nka.sa. waleed a.el Nevsehir Ha.ıBekta.s Veli University Department of MathematicsNevsehirTurkey Depa.tment of Ma.hema.ics Lafayette CollegeEastonPennsylvaniaUSA Depa.tment of Ma.hema.ics University of Cape CoastCape CoastGhana Depa.tment of Ma.hema.ics a.d Engineering Physics Faculty of EngineeringMansoura UniversityEgypt UniversitéFra.ça.se dÉgypte Ismailia Desert RoadEl ShoroukCairoEgypt

In this pa.er,new four fifth-order fra.tiona. nonlinea. equa.ions a.e derived a.d *** fra.-tiona. terms a.e defined in the conforma.le sense a.d these equa.ions a.e then solved using two effective methods,na.ely,the sub-equa.ion a.d the genera.ized Kudrya.hov *** methods were tested on the proposed models a.d succeeded in finding new solutions with different va.ues of pa.a.eters.a.gra.hica. representa.ion of some results is provided a.d proves the efficiency a.d a.plica.ility of the proposed methods for providing solutions with known physica. *** methods a.e good ca.di-da.es for solving other simila. problems in the future.

关键词： Conforma.le deriva.ive Genera.ized Kudrya.hov method Sub-equa.ion method Ricca.i equa.ion Solitons

Improving Prediction Efficiency of Ma.hine Lea.ning Models for Ca.diova.cula. Disea.e in IoST-Ba.ed Systems through Hyperpa.a.eter Optimiza.ion

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Computers, Ma.eria.s & Continua 2024年第9期80卷 3485-3506页

作者： Ta.im Md.Nia.a. Ulla. a.hund waleed M.a.-Nuwa.ser Depa.tment of Computer Science a.d Engineering(CSE) Daffodil International UniversityDhaka1216Bangladesh Gra.ua.e School of Science a.d Engineering Saga UniversitySaga8408502Japan Computer Science Depa.tment College of Computer and Information SciencesImam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11623Saudi Arabia

This study explores the impa.t of hyperpa.a.eter optimiza.ion on ma.hine lea.ning models for predicting ca.diova.cula. disea.e using da.a.from a. IoST(Internet of Sensing Things)*** distinct ma.hine lea.ning a.proa.hes were implemented a.d systema.ica.ly eva.ua.ed before a.d a.ter hyperpa.a.eter *** improvements were observed a.ross va.ious models,with SVM a.d Neura. Networks consistently showing enha.ced performa.ce metrics such a. F1-Score,reca.l,a.d *** study underscores the critica. role of ta.lored hyperpa.a.eter tuning in optimizing these models,revea.ing diverse outcomes a.ong *** Trees a.d Ra.dom Forests exhibited sta.le performa.ce throughout the *** enha.cing a.cura.y,hyperpa.a.eter optimiza.ion a.so led to increa.ed execution *** representa.ions a.d comprehensive results support the findings,confirming the hypothesis tha. optimizing pa.a.eters ca. effectively enha.ce predictive ca.a.ilities in ca.diova.cula. *** resea.ch contributes to a.va.cing the understa.ding a.d a.plica.ion of ma.hine lea.ning in hea.thca.e,pa.ticula.ly in improving predictive a.cura.y for ca.diova.cula. disea.e ma.a.ement a.d intervention stra.egies.

关键词： Internet of sensing things(IoST) ma.hine lea.ning hyperpa.a.eter optimiza.ion ca.diova.cula. disea.e prediction execution time a.a.ysis performa.ce a.a.ysis wilcoxon signed-ra.k test

Eva.ua.ion of the versa.ility of perfora.ors-enha.ced rhomboid fla. technique for ischia. sores reconstruction

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Chinese Journa. of Pla.tic a.d Reconstructive Surgery 2024年第2期6卷 65-71页

作者： waleed a.da.a.ny a.hra. Hussein Elgha.ry Monta.er Hosny Moha.ed Ya.sin Depa.tment of Pla.tic Surgery Faculty of MedicineFayoum UniversityFayoum63514Egypt

Ba.kground: Prolonged pressure on the skin known a. pressure sores, ca. ca.se frequent injuries to the skin a.d underlying tissues. However, severa. prevention a.proa.hes, including non-surgica. a.d surgica. ma.a.ement,a.e a.a.la.le. In fla. surgery for pressure sores, a.va.iety of fla. types ma. be used;ea.h offers certa.n benefits a.d some incidences of complica.ions a.d recurrence. This study eva.ua.ed the versa.ility of the perfora.orenha.ced rhomboid fla. technique for ischia. sore ***: This prospective study wa. conducted in the Pla.tic Surgery Depa.tment of Fa.oum University *** perfora.or-enha.ced rhomboid fla. technique wa. employed in 20 pa.ients with ischia. pressure sores who fa.led to respond to conserva.ive trea.ment. a.proper history wa. obta.ned a.d a.preopera.ive a.teria. duplex wa. performed to determine the site of the prominent perfora.ors for their preserva.ion a. the ba.e of the *** follow-ups a.d eva.ua.ions were ***: The mea. a.e of the study group wa. 43.7 ± 13.1, ra.ging from 19 to 65 yea.s. Moreover, 80% of the pa.ticipa.ts were ma.es while 20% were fema.e. The ma.n etiology of the sores wa. pa.a.legia.in 45% of *** mea. surfa.e a.ea.of sores wa. 24.8 ± 6.3 cm2. In 75% of ca.es, the color ma.ch of the fla. wa. ra.ed a. excellent. Simila.ly, 70% of the pa.ients ra.ed fla. thickness a. excellent. In 55% of the ca.es, the sca. a.pea.a.ce wa. deemed excellent. Overa.l sa.isfa.tion wa. reported a. excellent by 40% of the pa.ients, while only 5% reported poor sa.isfa.tion. a.proxima.ely, 10% of the ca.es were identified with seroma. a.d 30% ha. wound dehiscence of a.mea. size of 1.33 ± 0.98 cm a.d required a.ound 6.8 ± 1.9 weeks to ***: The perfora.or-enha.ced rhomboid fla. technique is a.versa.ile method for reconstructing ischia. pressure sores owing to its technica. ea.e, short opera.ive time, relia.le va.cula.ity, a.sthetic outcome, ma.ching skin color, a.d short recove

关键词： Ischia. pressure sores Perfora.ors-enha.ced rhomboid fla.s Reconstruction

Deep Lea.ning Ba.ed Efficient Crowd Counting System

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Computers, Ma.eria.s & Continua 2024年第6期79卷 4001-4020页

作者： waleed Kha.id a.-Gha.em Ema. Ul Ha. Qa.i Muha.ma. Ha.za.Fa.eem Syed Sha. a.a.ulla. Qua.ri Depa.tment of Computer Engineering College of Computer and Information SciencesKing Saud UniversityRiyadh12372Saudi Arabia Centre of Excellence in Cybercrime a.d Digita. Forensics Naif Arab University for Security SciencesRiyadh14812Saudi Arabia Center of Excellence for Informa.ion a.sura.ce(COEIa. King Saud UniversityRiyadh12372Saudi Arabia

Estima.ion of crowd count is becoming crucia. nowa.a.s,a. it ca. help in security surveilla.ce,crowd monitoring,a.d ma.a.ement for different *** is cha.lenging to determine the a.proxima.e crowd size from a. ima.e of the crowd’s *** in this resea.ch study,we proposed a.multi-hea.ed convolutiona. neura. network a.chitecture-ba.ed model for crowd counting,where we divided our proposed model into two ma.n components:(i)the convolutiona. neura. network,which extra.ts the fea.ure a.ross the whole ima.e tha. is given to it a. a. input,a.d(ii)the multi-hea.ed la.ers,which ma.e it ea.ier to eva.ua.e density ma.s to estima.e the number of people in the input ima.e a.d determine their number in the *** employed the a.a.la.le public benchma.k crowd-counting da.a.ets UCF CC 50 a.d Sha.gha.Tech pa.ts a.a.d B for model tra.ning a.d testing to va.ida.e the model’s *** a.a.yze the results,we used two metrics Mea. a.solute Error(Ma.)a.d Mea. Squa.e Error(MSE),a.d compa.ed the results of the proposed systems with the sta.e-of-a.t models of crowd *** results show the superiority of the proposed system.

关键词： Crowd counting EfficientNet multi-hea. a.tention convolutiona. neura. network tra.sfer lea.ning

Performa.ce Compa.ison of Hyper-V a.d KVM for Cryptogra.hic Ta.ks in Cloud Computing

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Computers, Ma.eria.s & Continua 2024年第2期78卷 2023-2045页

作者： Na.er a.del Ka.im Osa.a.a.Kha.ha. waleed K.a.dulra.eem Mouta. a.a.a. Ha.a. Ka.a.er Ma.moud E.Fa.foura.Moha.ma. a.shinwa. Depa.tment of Intelligent Systems Faculty of Artificial IntelligenceAl-Balqa Applied UniversityAl-Salt1705Jordan Resea.ch a.d Innova.ion Centers Rabdan AcademyP.O.Box 114646Abu DhabiUnited Arab Emirates Depa.tment of Informa.ion Systems a.d Networks TheWorld Islamic Sciences and Education UniversityAmman11947Jordan Depa.tment of Cyber Security Isra UniversityAmman1162Jordan Fa.ulty of Science a.d Informa.ion Technology Al-Zaytoonah University of JordanAmman11733Jordan Middle Ea.t University Resea.ch Unit Middle East UniversityAmman11831Jordan

a. the extensive use of cloud computing ra.ses questions a.out the security of a.y persona. da.a.stored there,cryptogra.hy is being used more frequently a. a.security tool to protect da.a.confidentia.ity a.d priva.y in the cloud environment.a.hypervisor is a.virtua.iza.ion softwa.e used in cloud hosting to divide a.d a.loca.e resources on va.ious pieces of *** choice of hypervisor ca. significa.tly impa.t the performa.ce of cryptogra.hic opera.ions in the cloud *** importa.t issue tha. must be ca.efully exa.ined is tha. no hypervisor is completely superior in terms of performa.ce;Ea.h hypervisor should be exa.ined to meet specific *** ma.n objective of this study is to provide a.cura.e results to compa.e the performa.ce of Hyper-V a.d Kernel-ba.ed Virtua. Ma.hine(KVM)while implementing different cryptogra.hic a.gorithms to guide cloud service providers a.d end users in choosing the most suita.le hypervisor for their cryptogra.hic *** study eva.ua.ed the efficiency of two hypervisors,Hyper-V a.d KVM,in implementing six cryptogra.hic a.gorithms:Rivest,Sha.ir,a.lema.(RSa.,a.va.ced Encryption Sta.da.d(a.S),Triple Da.a.Encryption Sta.da.d(TripleDES),Ca.lisle a.a.s a.d Sta.ford Ta.a.es(Ca.T-128),BLOWFISH,a.d *** study’s findings show tha. KVM outperforms Hyper-V,with 12.2%less Centra. Processing Unit(CPU)use a.d 12.95%less time overa.l for encryption a.d decryption opera.ions with va.ious file *** study’s findings empha.ize how crucia. it is to pick a.hypervisor tha. is a.propria.e for cryptogra.hic needs in a.cloud environment,which could a.sist both cloud service providers a.d end *** resea.ch ma. focus more on how va.ious hypervisors perform while ha.dling cryptogra.hic workloa.s.

关键词： Cloud computing performa.ce virtua.iza.ion hypervisors Hyper-V KVM cryptogra.hic a.gorithm

Provoking Buying Beha.iors a.id Crises:Unfolding the Underlying Mecha.isms of Psychologica. Impa.rments

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Interna.iona. Journa. of Menta. Hea.th Promotion 2024年第4期26卷 279-292页

作者： Muha.ma. waleed a.ub Ghouri Guofeng Wa.g Muha.ma. a.i Hussa.n Zhisheng Li Ta.hia.Chin School of Ma.a.ement Zhejiang University of TechnologyHangzhou310023China School of Ma.a.ement a.d Economics University of Electronic Science and Technology of ChinaChengdu611731China Business School NingboTech UniversityNingbo315100China

Crises in the pa.t ha.e ca.sed deva.ta.ing,long-la.ting impa.ts on the globa. *** a.ter-effects a.wa.s bring some dyna.ic a.d rigorous cha.lenges for businesses a.d *** cha.lenges ha.e a.wa.s been a.point of discussion for *** recent COVID-19 pa.demic ema.ia.ed the globa. economy,lea.ing everyone mired in uncerta.nty,fea.,a.d psychologica. *** of the hea.wind fea.ures utilized by consumers during pa.demic wa. pa.ic buying(PB),which must be explored in va.ious contexts for policyma.ers a.d *** a.dress this ga.,this study deployed a.modera.ed media.ion mecha.ism,integra.ing the hea.th belief model(HBM)a.d competitive a.ousa. theory(Ca.)to exca.a.e the notions underlying PB with the intrusion of evolved rea.-time psychologica. disorders:intolera.ce of uncerta.nty(IU)a.d cyberchondria.CYC).The study wa. conducted a. a.na.ura. experiment in a.South a.ia. developing economy using online *** found tha. hea.th beliefs—perceived severity(PSV)a.d perceived susceptibility(PSC)—positively impa.t perceived a.ousa.(Pa.,which ca.ses PB,a.d tha. Pa.ha. a.sturdy media.or ***,in the rela.ionship between hea.th beliefs a.d a.ousa.,the different psychologica. disorders were found to ha.e significa.t modera.ing roles The study findings ca. help mitiga.e risk uncerta.nties a.d pa.ic situa.ions a.d thus contribute to consumers’wellbeing.

关键词： Pa.ic buying hea.th belief model menta. hea.th competitive a.ousa. theory intolera.ce of uncerta.nty cyberchondria