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Effect of Cryogenic Treatment on Properties of Cr8-Type Cold Work Die Steel

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Journal of Iron and Steel Research International 2010年第6期17卷 43-46,59页

作者： chi Hong-xiao MA Dang-shen YONG Qi-long WU Li-zhi ZHANG Zhan-pu WANG Yong-wei Faculty of Materials Science and Engineering Kunming University of Science and Technology Kunming 650093 Yunnan China Institute for Structural Materials Central Iron and Steel Research Institute Beijing 100081 China Heye Special Steel Co Ltd Shijiazhuang 050031 Hebei China

The effect of cryogenic treatment on the properties of Cr8-type cold work die steel was investigated. The results show that cryogenic treatment increases hardness by decreasing retained austenite, but the degree depends on the austenitizing temperature. When quenching at lower austenitizing temperature, the steel can obtain higher tough- ness by cryogenic treatment substituting conventional treatment process. Cryogenic time has little effect on cryogenic treatment. Conversely, cryogenic temperature has a great effect on cryogenic treatment and the effect of cryogenic treatment is more obvious with decreasing cryogenic temperature. In addition, deep cryogenic treatment improves the wear resistance by precipitating more homogeneous specific carbides.

关键词： cryogenic treatment tool steel cold work die steel property wear resistance

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黄疸中医诊疗专家共识(2023)

临床肝胆病杂志 2024年第10期40卷 1959-1966页

作者：中华中医药学会脾胃病分会迟莉丽唐旭东孙大娟不详山东中医药大学附属医院

黄疸是临床比较常见的病症之一,尤以目睛黄染为主要特征,病证分型及选方不断改善。本共识阐述了黄疸的概念、病名沿革、病因病机、常见证候、临床治疗、疗效评定、预防调摄和转归与随访等内容,突出了临床实用性,体现了最新研究进展。

关键词：黄疸中医诊断治疗共识

Generation mechanism of quarter buckle in hot-rolled temper rolling

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Journal of Iron and Steel Research International 2022年第10期29卷 1619-1632页

作者： Hui Li Guan-yu Zhou An-rui He Zhi-hong Zhang chi-huan Yao Chao Liu Jian-wei Zhao Wei-gang Li Jian Shao Institute of Engineering Technology University of Science and Technology BeijingBeijing100083China Handan Iron and Steel Group Co. Ltd.Handan056015HebeiChina Engineering Research Centre for Metallurgical Automation and Measurement Technology of Ministry of Education Wuhan University of Science and TechnologyWuhan430081HubeiChina

To reveal the generation mechanism of the quarter buckle in the process of hot-rolled temper rolling,the elastic–plastic finite element method is used to calculate the deformation of the roll and the strip during the temper *** change of the cross section of the strip and the distribution of the longitudinal stress are analysed under different bending forces to obtain the boundary conditions of the quarter *** generation of the quarter buckle is further analysed from the bending and contact flattening of the roll system and the elastic recovery of the strip after *** found that the quarter buckle is closely related to the high-order distribution of the contact flattening between the work roll and the strip and is less affected by the bending deformation of the roll and the contact flattening between the ***,a new work roll contour of the locally variable crown is proposed to change the distribution of contact flattening between the work roll and the *** is verified through theoretical calculations and industrial applications that the new contour can effectively improve the quarter buckle.

关键词： Quarter buckle Contact flattening Roll contour Finite element method Hot-rolled temper rolling

Carbonization fabrication of a piezoresistive sensor with improved sensitivity via Ni decoration of carbonized cotton fibers

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Science china(Technological Sciences) 2022年第12期65卷 3000-3009页

作者： HE Xiang WANG FengMing LIANG YiYing WU JiaWei LIANG JiongHong SHEN GengZhe LI BaiJun SU DaoJian ZHANG chi SONG WeiDong HE Xin School of Applied Physics and Materials Wuyi UniversityJiangmen 529020China School of Materials and Energy Guangdong University of TechnologyGuangzhou 510006China

The development of wearable electronics urgently requires the cost-effective and scalable fabrication of high-performance pressure *** work aims to develop a simple carbonization strategy to facilitate sensor sensitivity by decorating discrete nickel nanoparticles on carbonized cotton fibers(CCFs).The increased air gap between the fibers at the unloading state,as well as the enlargement of the deformation distance and the contact area between the conductive materials at the loading state,contribute to a more significant resistance ***,the sensitivity of the piezoresistive sensor is improved more than 5 times within 1 N by introducing Ni nanoparticles,and it is characterized by a rapid response(~160 ms)and recovery(~100 ms),wide detection range(~20 N/~130 kPa),and good durability(~4000 cycles).The flexible sensor has been successfully demonstrated to monitor human movements,physical stimuli,and pressure ***,the proposed device can control temperature accurately as a uniform and large-scale *** work reveals that the Ni@CCFs-based sensor is prospective in wearable electronics,artificial intelligence,health monitoring,medical diagnosis and treatment.

关键词： carbonized cotton fabric Ni nanoparticles flexible piezoresistive sensor wearable device

UPLC-MS/MS法测定广叶绣球菌不同生长阶段栽培基质中有机酸含量及其对菌丝生长的影响

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食药用菌 2024年第5期32卷 325-332页

作者：刘晓瑜肖冬来马璐杨驰林辉江晓凌福建省农业科学院食用菌研究所特色食用菌繁育与栽培国家地方联合工程研究中心福建福州350014

为探究绣球菌生长发育过程中有机酸的代谢情况,采用超高效液相色谱串联质谱法(UPLC-MS/MS),以负离子多反应监测(MRM)模式测定广叶绣球菌栽培基质未接种阶段(0 d)、菌丝阶段(40 d)、原基阶段(60 d)及子实体生长阶段(80 d)26种有机酸的含... 详细信息

为探究绣球菌生长发育过程中有机酸的代谢情况,采用超高效液相色谱串联质谱法(UPLC-MS/MS),以负离子多反应监测(MRM)模式测定广叶绣球菌栽培基质未接种阶段(0 d)、菌丝阶段(40 d)、原基阶段(60 d)及子实体生长阶段(80 d)26种有机酸的含量,并研究主要有机酸对菌丝生物量和菌丝生长速度的影响。结果表明:各有机酸在其线性范围内与峰面积呈良好的线性关系(r2≥0.99),检出限在2.0~100.0 ng/mL;有13种有机酸在各阶段均能检测到,其中苹果酸、L-焦谷氨酸、柠檬酸、D-葡萄糖醛酸和酒石酸变化趋势明显,浓度变化分别为113.222~13.826μg/g、41.349~1.418μg/g、16.821~46.399μg/g、15.653~96.850μg/g和4.125~66.550μg/g;酒石酸和L-焦谷氨酸在试验浓度0.02~0.20 g/L范围内均对菌丝生长有显著促进作用,柠檬酸和苹果酸则在添加浓度较高时对菌丝生长促进作用显著。研究有机酸在栽培过程中的变化趋势有利于探究绣球菌基质降解机理,同时也可将其作为安全的营养添加剂用于配方优化。

关键词：广叶绣球菌超高效液相色谱串联质谱法有机酸菌丝生长

中药调控肠道菌群改善阿尔茨海默病的研究进展

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药学研究 2024年第1期43卷 67-73页

作者：曾春晖李绍燕周观琳池鑫宇杨柯广西中医药大学广西南宁530200

阿尔茨海默病(Alzheimer′s disease,AD)是一种在中老年群体发病率高,严重影响生活质量的进行性神经退行性疾病,发病机制未明确,随着微生物-肠-脑轴领域的研究兴起,研究人员对中药用于治疗AD的深入研究,中药调控肠道菌群在AD的发生和发... 详细信息

阿尔茨海默病(Alzheimer′s disease,AD)是一种在中老年群体发病率高,严重影响生活质量的进行性神经退行性疾病,发病机制未明确,随着微生物-肠-脑轴领域的研究兴起,研究人员对中药用于治疗AD的深入研究,中药调控肠道菌群在AD的发生和发展进程中发挥的作用愈发受到重视。本文从AD与肠道菌群的关系,中药调节肠道菌群改善AD的研究现状进行综述,以期为中药防治AD的研究提供参考。

关键词：中药肠道菌群阿尔茨海默病

Knot formation in the feeding jejunostomy tube:A case report and review of the literature

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World Journal of Gastroenterology 2007年第6期13卷 973-974页

作者： Guo-Shiou Liao Huan-Fa Hsieh Meng-Hang Wu Teng-Wei Chen Jyh-Cherng Yu Yao-chi Liu Department of Surgery Tri-Service General Hospital Penghu Branch National Defense Medical Center Taiwan China Division of General Surgery Department of Surgery Tri-Service General Hospital National Defense Medical Center Taipei Taiwan China Department of Surgery Yee-Zen General Hospital Taiwan China Department of Surgery Show Chwan Memorial Hospital Changhua Taiwan China

Jejunostomy feeding tubes provide surgeons with an excellent method for providing nutritional support, but there are several complications associated with a tube jejunostomy, including complications resulting from placement of the tube, mechanical problems related to the location or function and development of focally thickened small-bowel folds. A 76-year old man who presented with multiple medical diseases was admitted to our hospital due to aspiration pneumonia with acute respiratory failure and septic shock. He underwent exploratory laparotomy with feeding jejunostomy using a 14-French nasogastric tube for nutritional support. However, occlusion of the feeding tube was found 30 d after operation, and a rare complication of knot formation in the tube occurred after a new tube was replaced. On the following day, the tube was removed and replaced with a similar tube, which was placed into the jejunum for only 15 cm. The patient's feedings were maintained smoothly for two months. Knot formation in the feeding tube seems to be very rare. To our knowledge, this is the third case in the literature review. Its incidence is probably related to the length of the tube inserted into the lumen.

关键词： Feeding jejunostomy tube Complications Knot formation

ARTP法改良变色栓菌ATCC20869发酵漆酶

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齐鲁工业大学学报 2024年第5期38卷 47-57页

作者：闫忠杰王俊明刘新利张弛李秀芳齐鲁工业大学(山东省科学院)生物工程学部山东济南250353

变色栓菌漆酶是一种含铜的多酚氧化酶,可氧化多种酚类和芳香族化合物,主产物为水且几乎不产生有毒副产物,具有较好的应用前景,但变色栓菌漆酶较低的产量限制了其进一步应用。本研究利用ARTP技术成功地从变色栓菌ATCC20869中突变出新的... 详细信息

变色栓菌漆酶是一种含铜的多酚氧化酶,可氧化多种酚类和芳香族化合物,主产物为水且几乎不产生有毒副产物,具有较好的应用前景,但变色栓菌漆酶较低的产量限制了其进一步应用。本研究利用ARTP技术成功地从变色栓菌ATCC20869中突变出新的突变菌株TA-03。为了进一步提高漆酶产量,利用单因素摇瓶发酵实验和响应面分析法,优化了漆酶发酵条件。结果表明:在法尼醇添加量为4.48 mmol/L、硫酸铜添加量为1.90 mmol/L,pH为4.00的条件下,突变株漆酶产量达到了(283.77±8.91)U/mL。为深入探究突变菌株TA-03漆酶酶活性提高的原因,对其进行重测序和转录组分析。研究结果显示,漆酶活性区域氨基酸的突变以及新陈代谢等方面的富集导致了漆酶活性的提升。这为变色栓菌漆酶的实际应用进行了有意义的探索,提升了漆酶在发酵工业上的应用。

关键词：变色栓菌漆酶 ARTP 响应面转录组分析

Non-secretory multiple myeloma expressed as multiple extramedullary plasmacytoma with an endobronchial lesion mimicking metastatic cancer:A case report

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World Journal of Clinical Cases 2022年第22期10卷 7899-7905页

作者： Seul Bi Lee chi Young Park Hee Jeong Lee Ran Hong Woo Shin Kim Sang-Gon Park Department of Hemato-oncology Chosun University HospitalGwangju 501-717South Korea Department of Pathology Chosun University HospitalGwangju 501-717South Korea Department of Laboratory Medicine Chosun University HospitalGwangju 501-717South Korea

BACKGROUND Non-secretory multiple myeloma(MM)is a rare condition that accounts for only 3%of MM cases and is defined by normal serum and urine immunofixation and a normal serum free light chain ***-secretory MM with multiple extramedullary plasmacytomas derived from endobronchial lesions is extremely rare and can be misdiagnosed as metastasis of solid *** SUMMARY A 36-year-old man presented with progressive facial swelling and nasal congestion with *** imaging studies revealed an endobronchial mass in the left bronchus and a large left maxillary mass with multiple destructive bone metastatic *** initially presented with lung cancer and multiple ***,pathologic reports showed multiple extramedullary plasmacytomas in the left maxilla and the left *** was no change in the serum and urine monoclonal protein levels,and no abnormalities were observed in laboratory examinations,including hemoglobin,calcium,and creatinine *** bone marrow was hypercellular,with 13.49%plasma *** patient was diagnosed with non-secretory MM expressed as multiple extramedullary plasmacytomas with endobronchial lesions in a rare *** therapy for symptomatic lesions with high-dose dexamethasone was started,and the size of the left maxillary sinus lesion dramatically *** the future,chemotherapy will be administered to control lesions in other *** We present a rare case of non-secretory MM with multiple extramedullary plasmacytoma with an endobronchial lesion.

关键词： Maxillary mass lesion Destructive bone metastatic lesion Multiple extramedullary plasmacytoma Endobronchial lesion Non-secretory multiple myeloma Case report