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Overall and cause-specific survival for mucoepidermoid carcinoma of the major salivary glands:Analysis of 2210 patients

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World Journal of clinical Oncology 2020年第12期11卷 1029-1044页

作者： Zachary c Taylor Erin A Kaya Jeffrey D Bunn Zachary D Guss Brian J Mitchell Robert K Fairbanks Wayne T Lamoreaux Aaron E wagner Ben J Peressini christopher M Lee Department of Radiation Oncology Cancer Care NorthwestSpokaneWA 99202United States MD Program Elson S.Floyd College of MedicineSpokaneWA 99202United States Surgery Spokane EarNoseand ThroatSpokaneWA 99201United States Department of Biostatistics DataWorks NorthwestLLCCoeur D'AleneID 83815United States

BAcKGROUND Mucoepidermoid carcinoma(MEc)is a rare malignancy of the head and neck;however,it accounts for a majority of the tumors of the salivary *** study used a national population-based registry to describe the pre-treatment and treatment-related prognostic factors that influence survival in patients with MEc of the major salivary *** our knowledge,this is the largest populationbased study examining predictors of both overall and cause-specific survival of MEc of the major salivary *** To identify prognostic factors influencing overall survival(OS)and cause-specific survival(cSS)of patients with MEc of the major salivary *** We used the Surveillance,Epidemiology and End-Results Database of the National cancer Institute to investigate a variety of factors that could influence survival of patients diagnosed with mucoepidermoid carcinoma of the major salivary glands.A total of 2210 patients diagnosed with MEc of the major salivary glands during the years of 1975-2016 were *** primary endpoints were OS and *** regression analysis was used to perform univariate and multivariate analyses of clinical variables such as age at diagnosis,diagnosis year,sex,race,tumor size,stage,grade,treatment with or without surgical excision,and adjuvant radiotherapy *** A total of 2210 patients diagnosed with MEc of the major salivary glands met inclusion *** this study,95%of patients underwent surgical excision and 41%received adjuvant radiation *** OS time for Grade I,II,and III/IV was 401 mo(±48.25,95%cI),340 mo(±33.68,95%cI)and 55 mo(±11.05,95%cI),*** analysis revealed that lack of surgical excision was associated with decreased OS[hazard ratio(HR)4.26,Pcalized disease had improved OS compared to both regional and distant disease(HR 3.07 and 6.96,respectively,P<0.0001).Additionally,univariate analysis demonstrated that male sex,age over 50 at diagnosis,G

关键词： Mucoepidermoid carcinoma Salivary gland neoplasia Surveillance,Epidemiology and End-Results Head and neck cancer Prognostic factors Major salivary glands

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视学纲要

视学纲要

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丛书名：厦门大学教育学院丛书

1933年

作者：（美）瓦格涅（c.A.wagner）姜琦杨慎宜译

书名原文:common sense in school supervision:分19章。有教学视察的实施、经过视学后教学的刷新、兼课的校长的教学视察、为什么教学视察是必要的等。附：视学制度研究调查表3种。

关键词：文化、科学、教育、体育教育教育行政

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Fuzzy Modelling for Predicting the Risk of Recurrence and Progression of Superficial Bladder Tumors

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Applied Mathematics 2018年第10期9卷 1091-1103页

作者： Laércio L. Vendite Kenia D. Savergnini Ubirajara Ferreira wagner E. Matheus Unicamp Campinas Brazil

Nowadays, bladder cancer is the fourth most common cancer in adults and the second most frequent urogenital tumor. Predicting recurrence and progression of superficial bladder tumors, with available clinical information to decide the therapy to be used is a difficult task. In this work, two mathematical models were developed to help specialists on the decision process. The mathematical tool used to formulate the model was the fuzzy sets theory, due to its capacity in dealing with uncertainties inherent in medical concepts. In the first model, Stage, Grade and Size of the tumor were also considered input variables and Risk of Recurrence of a superficial bladder tumor as output variable of the first Fuzzy Rule-Based Systems (FRBS). In the second model, in addition to the Stage, Grade and Size of the tumor, it was also considered as input variable of a second FRBS carcinoma in situ and, the Risk of Progression of superficial tumors as an output variable. For each model, simulations were made with data originated from of patients of the clinics Hospital/ UNIcAMP and A. c. camargo Hospital of São Paulo, with the aim to verify the reliability of results generated by the two systems. From a database and the possibility found by FRBS, after the possibility-probability transformation, we can generate the real probability of each fuzzy output set.

关键词： Bladder cancer Fuzzy Modelling Recurrence Risk Progression Risk

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使用磁敏感加权成像评估脊髓神经根病变中颈椎椎间孔狭窄情况

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国际医学放射学杂志 2019年第3期 375-376页

作者：田恬 G.Engel Y.Y.Bender L.c.Adams S.M.Boker U.L.Fahlenkamp M.wagner Department of Radiology Charité-University Medicine Berlin

摘要目的以cT结果为参考标准,评价磁敏感加权MRI(SW-MRI)对颈椎椎间孔狭窄(FS)的诊断效果,并与常规MRI序列影像进行比较。材料与方法前瞻性纳入21例

关键词：椎间孔狭窄 SW 神经根病敏感度特异度

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经理人财务管理手册英汉对照

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丛书名：职业成功必读书架

2006年

作者：（美）凯瑟琳·华格纳（Katherine wagner）陈仪译

本书用简单易懂的文字，为读者提供了24项关键知识，当中包含会计、财务报表和预算编制的各项基本常识。

ISBN: (数字)7302123640

ISBN: (纸本)7302123640

本书用简单易懂的文字，为读者提供了24项关键知识，当中包含会计、财务报表和预算编制的各项基本常识。

关键词：企业管理财务管理

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磁敏感加权成像对椎体骨折的评估

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国际医学放射学杂志 2018年第4期 492-493页

作者： S.M.Bker L.c.Adams Y.Y.Bender M.wagner T.Diekhoff E.Fallenberg 陈圣妮 Department of Radiology Charité

目的以cT为参考标准,检测MR磁敏感加权成像（s MRI）和常规序列评估椎体骨折的诊断性能。方法这项前瞻性研究共纳入39例病人行MRI T1/T2/快速反转恢复（TIRM）和s MRI扫描,共发现88个椎体骨折（45个已愈合,43个未愈合）。所有骨折均以c... 详细信息

目的以cT为参考标准,检测MR磁敏感加权成像（s MRI）和常规序列评估椎体骨折的诊断性能。方法这项前瞻性研究共纳入39例病人行MRI T1/T2/快速反转恢复（TIRM）和s MRI扫描,共发现88个椎体骨折（45个已愈合,43个未愈合）。所有骨折均以cT作为参考标准。评估所有序列中椎体后部皮质移位程度和高度,有无骨折线及皮质断裂。计算MRI和cT之间的敏感度、特异度和一致性。结果相比T1/T2/TIRM序列,sMRI显示椎体后部皮质受累（敏感度98%,特异度100%）、骨折线（86%/99%）和皮质断裂（93%/100%）的诊断准确度最高。对椎体后部皮质移位和高度的评价,sMRI与cT结果的一致性最接近（R2=0.96;95%cI:-0.92～0.89/R2=0.97;95%cI:-1.67～1.23）,观察者间一致性也最接近（R2=0.97;95%cI:-0.71～1.01）。结论 sMRI能够可靠地评估椎体骨折时椎体后部皮质移位和高度改变、皮质断裂以及骨折线,较常规MRI准确性更高,尤其是对未愈合的骨折椎体。

关键词：磁敏感加权成像 cT 椎体骨折 MRI

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Testing the causes of synchronous abrupt climate changes in the Asian summer monsoons and the North Atlantic during the last glacial and Holocene

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地球环境学报 2011年第1期 318-318页

作者： Morrill c Otto-Bliesner B wagner A cooperative Institute for Research in Environmental Sciences(cIRES) University of colorado at Boulder and NOAA's National Climatic Data Center Paleoclimatology Branch National center for Atmospheric Research

Linkages between the summer monsoons（Indian and East Asian） and temperature conditions in the North Atlantic are well-documented from paleoclimate *** the reasons for this teleconnection is important for predicting the future behavior of the monsoons,especially as anthropogenic climate change continues to cause significant impacts in high-latitude areas such as the North Atlantic and Arctic.I will review proxy evidence and present modeling results to examine the physical mechanisms of this teleconnection for three past time periods:stadials/interstadials during the last glacial period,the 8.2 ka event and mid-Holocene abrupt climate change around5.5 ***,to test the hypothesis that pulses of freshwater added to the North Adantic could have led to a remote climate response in Asia during the last glacial,I will show results from an experiment using the National center for Atmospheric Research（NcAR） coupled community climate System Model,version *** this experiment with Last Glacial Maximum boundary conditions,a 1 Sverdrup(1×10;m;·s;) freshwater hosing was applied over the North Atlantic between 50°N and 70°N for 100 *** monsoon precipitation decreased 40%,and appeared to be linked more to changes in atmospheric circulation rather than to changes in snow cover or tropical sea surface ***,I will review the growing proxy evidence for an 8.2 ka event in monsoonal Asia and compare this evidence to results from another ccSM experiment that uses the newest reconstructions of lake and ice sheet meltwater fluxes causing this ***,I will present a new global synthesis of proxy records from the midHolocene and show evidence for a significant abrupt climate change at about 5.5 ka that is characterized by a stepchange with increased sea ice in the North Atlantic and decreased monsoon *** abrupt event coincides with a short-lived decrease in solar irradiance,and may imply monsoon sensitivity to very small changes in

关键词： Atlantic glacial abrupt Holocene monsoon proxy anthropogenic latitude Arctic records

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Full-aperture backscatter diagnostics and applications at the Texas Petawatt Laser facility

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chinese Optics Letters 2014年第A2期12卷 152-156页

作者： c. Wang c. wagner G. Dyer E. Gaul N. Kandadai N. Riley D. Kuk E. Mccary A. Meadows I. Pomerantz M. Spinks T. Borger A. Bernstein M. Donovan M. Martinez T. Ditmire Bjorn M. Hegelich center for High Energy Density Science University of Texas Austin Texas 78712

In this paper, we present the development and application of a full-aperture baekscatter diagnostics system at the Texas Petawatt Laser （TPW） facility. The diagnostic system includes three independent diagnostic stations. With this system, we obtained TPW on-shot focus properties, and high-harmonic spectral emission flOln solid foils （e.g., cu and Al） and their Si substrate in an experiment to study laser hole boring, which show the hole-boring mechanism at relativistic intensities. The measured on-target full-power focal spots from ultrathin film targets help determine the optimum target thickness at certain laser contrast parameters for particle acceleration and neutron generation experiment, which is also a relative measurement of shot-to- shot intensity fluctuations.

关键词： 320.7090 Ultrafast lasers 020.2649 Strong field laser physics 300.6360 Spectroscopy, laser 350.5400 Plasmas

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Maize carbohydrate Partitioning Defective33 Encodes an McTP Protein and Functions in Sucrose Export from Leaves

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Molecular Plant 2019年第9期12卷 1278-1293页

作者： Thu M.Tran Tyler J.Mccubbin Saadia Bihmidine Benjamin T.Julius R.Frank Baker Martin Schauflinger clifford Weil Nathan Springer Paul chomet Ruth wagner Jeff Woessner Karen Grote Jeanette Peevers Thomas L.Slewinski David M.Braun Division of Biological Sciences’Interdisciplinary Plant Group Missouri Maize CenterUniversity of MissouriColumbiaMO 65211USA Division of Plant Sciences University of MissouriColumbiaMO 65211USA Electron Microscopy core Facility University of MissouriColumbiaMO 65211USA Department of Agronomy Purdue UniversityWest LafayetteIN 47907USA Department of Plant and Microbial Biology University of MinnesotaSaint PaulMN 55108USA NRGene Inc. 8910 University Center Lane\r\n S u ite 400San DiegoCA 92122USA Bayer crop Science ChesterfieldMO 63017USA National Key Laboratory for Plant cell Technology Agricultural Genetics InstituteHanoiVietnam

To sustain plant growth,development,and crop yield,sucrose must be transported from leaves to distant parts of the plant,such as seeds and *** identify genes that regulate sucrose accumulation and transport in maize(Zea mays),we isolated carbo/iydrafe part/f/ofi/ngf defecf/Ve33(cpd33),a recessive mutant that accumulated excess starch and soluble sugars in mature *** cpd33 mutants also exhibited chlorosis in the leaf blades,greatly diminished plant growth,and reduced ***33 encodes a protein containing multiple c2 domains and transmembrane *** localization experiments showed the cPD33 protein localized to plasmodesmata(PD),the plasma membrane,and the endoplasmic *** also found that a loss-of-function mutant of the cPD33 homolog in Arabidopsis,QUIRKY,had a similar carbohydrate hyperaccumulation *** labeled sucrose transport assays showed that sucrose export was significantly lower in cpd33 mutant leaves relative to wild-type ***,PD transport in the adaxial-abaxial direction was unaffected in cpd33 mutant ***,transmission electron microscopy revealed fewer PD at the companion cell-sieve element interface in mutant phloem tissue,providing a possible explanation for the reduced sucrose export in mutant ***,our results suggest that cPD33 functions to promote symplastic transport into sieve elements.

关键词： carbohydrate accumulation companion cells phloem, plasmodesmata sieve elements symplastictransport

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管状骨髓内病变的cT诊断

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放射学实践 1986年第3期 126-127页

作者： Von c.wagner-Manslau ,St.Feuerbach ,Th.Biehl ,洪光祥同济医科大学附属协和医院

管状骨的髓内占位病变,只有出现钙化或骨质样密度成分时,才能在常规X线片上见到.软组织密度的组织,则在X线平片上无改变.而cT检查能准确分析管状骨髓腔的微小对比差异,确定管状骨恶性骨肿瘤时髓腔内的病变范围和发现遗漏的病变.下面以... 详细信息

管状骨的髓内占位病变,只有出现钙化或骨质样密度成分时,才能在常规X线片上见到.软组织密度的组织,则在X线平片上无改变.而cT检查能准确分析管状骨髓腔的微小对比差异,确定管状骨恶性骨肿瘤时髓腔内的病变范围和发现遗漏的病变.下面以三个病例说明.

关键词：髓内管状骨骨皮质病变 cT

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