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Dosimetric Comparison of Intensity-Modulated Radiotherapy versus Three-Dimensional Conformal Radiotherapy for Patients with Brain Tumors

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Open Journal of Radiology 2014年第1期4卷 85-96页

作者： Doaa M. Al Zayat Ehab M. Attalla Hassan S. Abouelenein Yasser M. Elkem wafaa khalil Ayadi Al mostakbl Oncology Center Alex Egyp Cancer Management and Research Department Medical Research Institute Alex University Alex Egypt Faculty of Science Cairo University Cairo Egypt National Cancer Institute Cairo University Cairo Egypt

Purpose: To compare target dose distribution and dose to normal tissue for brain tumors using intensity-modulated and three-dimensional conformal radiotherapy. Methods and Materials: Twelve patients selected in the present study compared the dosimetry of intensity-modulated radiation therapy (IMRT) and three-dimensional conformal radiation therapy (3DCRT) techniques in patients treated with different diagnosis brain tumor. All patients underwent computed tomography planning in conjunction with magnetic resonance imaging fusion. Prescription dose and normal-tissue constraints were identical for both plans. The tolerance level for maximum dose was 6.0 Gy for lenses and 54.0 Gy for brain stem, and optical nerves. Target coverage was evaluated with the D98%, D95% and D2%. Normal tissue dose was evaluated with the maximum dose to lenses, brain stem, and optical nerves. Results: Mean and standard deviation values of PTV 98%, PTV 95% and PTV 2% in IMRT these values were 94.6 ± 2.3, 96.56 ± 1.67 and 106.5 ± 1.87 respectively;for 3DCRT were 92.7 ± 3.09, 95.58 ± 1.24 and 104.45 ± 2.73 respectively. IMRT plan provided reduced dose to brainstem (72.17 ± 29.967) and lenses (2.43 ± 2.39) relative to the 3DCRT plans for brainstem (73.05 ± 34.59) and lenses (7.65 ± 23.24). But optic nerves with IMRT significantly received higher doses (38.86 ± 32.15) than 3D-CRT (27.57 ± 31.45). Conclusion: Dose coverage of the planning target volume (PTV) and organ at risk (OAR) was better with IMRT. If PTV is distant to optical nerves and brainstem 3DCRT technique can be applied, and if the PTV is nearby OAR intensity-modulated treatment technique should be used.

关键词： Brain Cancer 3DCRT IMRT

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Secure Channel Estimation Using Norm Estimation Model for 5G Next Generation Wireless Networks

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Computers, Materials & Continua 2025年第1期82卷 1151-1169页

作者： khalil Ullah Song Jian Muhammad Naeem Ul Hassan Suliman Khan Mohammad Babar Arshad Ahmad Shafiq Ahmad Faculty of Information Engineering and Automation Kunming University of Science and TechnologyKunming650500China Department of Computer Science Abbottabad University of Science and TechnologyHavelianAbbottabad22500Pakistan Department of Computing and Electronics Engineering Middle East CollegeMuscat124Oman Department of CS&IT Pak-Austria Fachhochschule Institute of Applied Sciences and Technology MangHaripur22621Pakistan Industrial Engineering Department College of EngineeringKing Saud UniversityRiyadh11421Saudi Arabia

The emergence of next generation networks(NextG),including 5G and beyond,is reshaping the technological landscape of cellular and mobile *** networks are sufficiently scaled to interconnect billions of users and *** in academia and industry are focusing on technological advancements to achieve highspeed transmission,cell planning,and latency reduction to facilitate emerging applications such as virtual reality,the metaverse,smart cities,smart health,and autonomous *** continuously improves its network functionality to support these *** input multiple output(MIMO)technology offers spectral efficiency,dependability,and overall performance in *** article proposes a secure channel estimation technique in MIMO topology using a norm-estimation model to provide comprehensive insights into protecting NextG network components against adversarial *** technique aims to create long-lasting and secure NextG networks using this extended *** viability of MIMO applications and modern AI-driven methodologies to combat cybersecurity threats are explored in this ***,the proposed model demonstrates high performance in terms of reliability and accuracy,with a 20%reduction in the MalOut-RealOut-Diff metric compared to existing state-of-the-art techniques.

关键词： Next generation networks massive mimo communication network artificial intelligence 5G adversarial attacks channel estimation information security

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Diet fortification for mild and moderate picky eating in typically developed children:Opinion review of Middle East consensus

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World Journal of Clinical Pediatrics 2025年第1期14卷 139-148页

作者： Mohammed Al-Beltagi Elie Choueiry Najat Alahmadi Zeinab Demerdash wafaa Helmi Ayesh Khoula Al-Said Fatima Al-Haddad Sanaa Y Shaaban Eslam Tawfik Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511Egypt Department of Pediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain Paediatric Intensive and Critical Care Unit Hospital Hôtel Dieu de FranceBeirut 166830BeyrouthLebanon Department of Pediatric Gastroenterology Hepatology and NutritionMadina Maternity and Children HospitalKing Salman Medical CityAlmadina Almonawarh 41412Almadina AlmonawarhSaudi Arabia Department of Gastroenterology Hepatology and NutritionAl Amiri HospitalKuwait City 999044Kuwait Department of Nutrition Altadawi Speciality HospitalDubai 1853DubayyUnited Arab Emirates Department of Paediatric Gastroenterology Royal HospitalMuscat 1331MuscatOman Department of Dietetic Salmaniya Medical ComplexGovernment HospitalsAl Salmaniya 12ManamaBahrain Department of Pediatrics Faculty of MedicineAin Shams UniversityCairo 11591Egypt Department of Paediatric Faculty of MedicineSuez UniversitySuez 41522Egypt Department of Paediatric Sheikh Khalifa Medical CityAbu Dhabi 00000Abu DhabiUnited Arab Emirates

BACKGROUND Picky eating is a commonly observed behavior among children globally,negatively impacting their physical and mental *** common characteristics distinguish peaky eaters,including food selectivity,food neophobia,and food avoidance,there is no clear definition to assess this *** to the unavailability of data regarding picky eating,it wasn’t easy to estimate its *** To develop a regional protocol to help healthcare professionals identify and manage mild and moderate picky eating *** A virtual roundtable discussion was held in April 2021 to gather the opinions of seven pediatricians and two pediatric dietitians from eight Middle Eastern countries who had great experience in the management of picky *** discussion covered different topics,including clearly defining mild and moderate picky eating,identifying the role of diet fortification in these cases,and the possibility of developing a systematic approach to diet *** The panel identified picky eating as consuming an inadequate amount and variety of foods by rejecting familiar and unfamiliar *** of the time,moderate picky eating cases had micronutrient deficiencies with over-or undernutrition;the mild cases only showed inadequate food consumption and/or poor diet *** attention to the organic red flags like growth faltering and development delay and behavioral red flags,including food fixation and anticipatory gagging,will help healthcare professionals evaluate the picky eaters and the caregivers to care for their *** dietary supplementation and commercial food fortification play an important role in picky eating,they were no benefit in the Middle *** The panel agreed that food fortification through a food-first approach and oral nutritional supplements would be the best for Middle Eastern *** recommendations would facilitate identifying and managing picky-eating children in the Middle East.

关键词： Picky eating Diet fortification Children Protocol Roundtable discussion Middle East

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Microwave-Assisted Acetylated Lignin Loaded into Cellulose Acetate for Efficient UV-Shielding Films

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Journal of Renewable Materials 2025年第2期13卷 401-412页

作者： Ahmed M.khalil Samir Kamel Photochemistry Department National Research CentreGiza12622Egypt Cellulose and Paper Department National Research CentreGiza12622Egypt

Developing favorable bio-based polymers that replace petroleum-based plastics is an essential environmental *** is a by-product of the chemical pulping *** is a natural UV protection ingredient in broad-spectrum(UVA and UVB)*** could be partially and selectively acetylated in a simple,fast,and more reliable *** this work,a composite film was prepared with UV-resistant properties through a casting ***-based cellulose acetate(CA)was employed as a major matrix while nano-acetylated kraft lignin(AL-NPs)was used as filler during synthesizing UV-shielding films loaded with various amounts(1–5 wt.%)of *** lignin was acetylated through a simple and fast microwave-assisted process using acetic acid as a solvent and acetylating *** physicochemical and morphological characteristics of the prepared films were evaluated using different methods,including scanning electron microscopy(SEM),Fourier Transform Infrared Spectroscopy(FTIR),X-ray diffraction analysis(XRD),mechanical testing and contact angle *** UV-Vis spectroscopy optical investigation of the prepared films revealed that AL-NPs in the CA matrix showed strong UV *** feature demonstrated the effectiveness of our research in developing UV-resistant bio-based polymer ***,the prepared films can be considered as successful candidates to be applied in packaging applications.

关键词： Cellulose acetate microwave-assisted acetylation nano lignin acetate UV-shielding

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Effect of empowerment-based interventions on self-efficacy and selfcare capacity among patients with sickle cell disease:A randomized controlled trial

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International Journal of Nursing Sciences 2025年第1期12卷 42-50页

作者： Zohour Ibrahim Rashwan Hasan Abdali khalil Leena Mohamed Khonji Gayathripriya Narayanan Marwan Kamal Altheeb Roseben Pradeep Rajeswari Krishnasamy Magda Mohamed Bayoumi Pediatric Nursing Specialty Nursing DepartmentCollege of Health and Sport SciencesUniversity of BahrainZallaqKingdom of Bahrain Pediatric Nursing Department Faculty of NursingAlexandria UniversityEgypt Shaikh Jaber Al-Ahmed Al-Subah Health Centre Primary Health Care CentresBarbarKingdom of Bahrain Midwifery Specialty Nursing DepartmentCollege of Health and Sport SciencesUniversity of BahrainZallaqKingdom of Bahrain Nursing Department College of Health and Sport SciencesUniversity of BahrainZallaqKingdom of Bahrain Mental Health Nursing Speciality Nursing DepartmentCollege of Health and Sport SciencesUniversity of BahrainZallaqKingdom of Bahrain Medical-Surgical Nursing Specialty Nursing DepartmentCollege of Health and Sport SciencesUniversity of BahrainZallaqKingdom of Bahrain Medical-Surgical Nursing Department Faculty of NursingBeni-Suef UniversityEgypt

Objective:This study aimed to investigate the effect of empowerment-based interventions on selfefficacy and self-care capacity among adults with sickle cell disease(SCD).Methods:A randomized control trial was conducted[NCT06296654].A total of 76 patients were recruited by using a cluster sampling technique in the two health centers in Bahrain from February to May 2022 and randomly allocated to the intervention group(n=38)or control group(n=38).The intervention group received the empowerment-based intervention implemented through structured small-group discussion sessions,individualized consultations(5A model:assess,advise,agree,assist,and arrange),and follow-up sessions,while the control group received routine health *** Sickle Cell Self-Efficacy Scale(SCSES)and the Appraisal of the Self-Care Agency Scale-Revised(ASA-R)were measured at baseline and one month after the intervention among two groups of ***:A total of 68 patients completed the study(36 patients in the intervention group and 32 patients in the control group).After the intervention,the score of SCSES in the intervention group was 37.0(35.0,39.8)higher than the control group 28.0(25.2,32.0)(U=-6.121,P<0.001);the score of ASA-R in the intervention group was 61.0(58.3,65.0)higher than the control group 49.0(43.3,53.0)(U=-0.653,P<0.001).Conclusion:Adopting the empowerment-based intervention using the 5As model effectively improves self-efficacy and self-care capacity among patients with SCD.

关键词： Activities of daily living Sickle cell disease Self-efficacy Self-care

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Donor-specific antibodies against HLA-C,HLA-DP and HLA-DQ and their implications in kidney transplantation

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World Journal of Transplantation 2025年第2期15卷 30-48页

作者： Muhammad Abdul Mabood khalil Nihal Mohammed Sadagah Ishida Hediki Jackson Tan Salem H Al-Qurashi Center of Renal Diseases and Transplantation King Fahad Armed Forces Hospital JeddahJeddah 23311Saudi Arabia Department of Urology and Transplantation Tokyo Women's Medical University HospitalTokyo 162-8666Japan Department of Nephrology RIPAS Hospital Brunei DarussalamBrunei Muara BA1710Brunei Darussalam

HLA-C,HLA-DP and HLA-DQ are thought to be benign due to low expression and few initial negative ***,most allocation programs used HLA-A,HLA-B and HLA-DR antigens for *** the advent and use of single-bead antigen assays,more was learned about donor-specific antibodies(DSAs)against these *** in these antigens and antibodies grew when cases of acute antibody-mediated rejection(AMR),mixed rejections,chronic AMR,and reduced graft survival were reported with DSAs against these *** the deleterious effects of these DSAs are more pronounced in retransplants,harmful effects have also been observed in first-time *** against each of these antigens can trigger rejection *** combination with DSAs against HLA-A,HLA-B and HLA-DR can cause more *** has been shown that strategies that reduce mismatches for these antigen lead to fewer rejections and better graft *** is a need for greater consensus on the universal typing of these antigens prior to transplantation for better patient and graft *** review focuses on the interaction of these antigens with lymphocytes and killer immunoglobulin receptors,arguments for not typing them,detailed analyses of the literature about their harmful effects,potential strategies moving forward,and recommendations for the future.

关键词： Kidney transplantation HLA-C HLA-DP HLA-DQ Donor specific antibodies Review

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Glassy behaviour of random field Ising spins on Bethe lattice in external magnetic field

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Chinese Physics B 2011年第6期20卷 416-425页

作者： Khalid Bannora Galal Ismail wafaa Hassan Mathematics Department Faculty of Science Zagazig University Mathematics and Physics Department Faculty of Engineering Port Said Branch of Suez Canal University

The thermodynamics and the phase diagram of random field Ising model （RFIM） on Bethe lattice are studied by using a replica trick. This lattice is placed in an external magnetic field （B）. A Gaussian distribution of random field （hi） with zero mean and variance （hi2 = H2RF is considered. The free-energy （F）, the magnetization （M） and the order parameter （q） are investigated for several values of coordination number （z）. The phase diagram shows several interesting behaviours and presents tricritical point at critical temperature Tc = J/k and when HRF = 0 for finite z. The free-energy （F） values increase as T increases for different intensities of random field （HRE） and finite z. The internal energy （U） has a similar behaviour to that obtained from the Monte Carlo simulations. The ground state of magnetization decreases as the intensity of random field HRF increases, The ferromagnetic （FM） paramagnetic （PM） phase boundary is clearly observed only when z →∞. While FM PM-spin glass （SG） phase boundaries are present for finite z. The magnetic susceptibility （X） shows a sharp cusp at Tc in a small random field for finite z and rounded different peaks on increasing HRF.

关键词： random field replica trick coordination number order parameter susceptibility and phase diagram

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Impact of liver cirrhosis on morbidity and mortality of patients admitted to the hospital with necrotizing fasciitis

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World Journal of Hepatology 2025年第1期17卷 41-46页

作者： Mohamad El Labban Juliet Kotys Sabrina Makher Sai Shanmukha Sreeram Pannala khalil El Gharib Hamed Chehab Liliane Deeb Salim R Surani Department of Internal Medicine Mayo Clinic Health SystemMankatoMN 56001United States Department of Internal Medicine Staten Island University HospitalNew YorkNY 10305United States Department of Pulmonary/Critical Care Medicine Rutgers Robert Wood Johson Medical SchoolNew BrunswickNJ 08901United States Department of Infectious Diseases Indiana University School of MedicineIndianapolisIN 46202United States Department of Pulmonary and Critical Care Medicine Staten Island University HospitalNew YorkNY 10305United States Department of Medicine&Pharmacology Texas A&M UniversityCollege StationTX 77843United States

BACKGROUND Necrotizing fasciitis(NF)is a potentially fatal bacterial infection of the soft *** cirrhosis appears to be a contributing factor to higher morbidity and mor-tality in patients with *** research article explores the relationship between these two *** To evaluate whether liver cirrhosis increases morbidity and mortality in patients with NF,focusing on inpatient mortality,septic shock,length of stay,and hospital *** This retrospective cohort study utilized data from the Healthcare Cost and Utilization Project 2019 National Inpatient *** were identified as pa-tients with both NF and cirrhosis,while controls were *** study focused on inpatient mortality as the primary outcome,with secondary outcomes including surgical limb amputation,mechanical ventilation rates,septic shock,length of stay,and hospital *** A total of 14920 patients were admitted to the hospital for management of NF,of which 2.11%had liver *** mortality was higher in cirrhotic patients(9.5%vs 3%;adjusted odds ratio=3.78;P value=0.02).Cirrhotic patients also had higher rates of septic shock(10.5%vs 4.9%,P value<0.01).Length of hospital stay,total charges,and rates of mechanical ventilation were not statistically different between *** Liver cirrhosis is an independent risk factor of in-hospital mortality and morbidity in patients with *** should be aware of this association to ensure better clinical outcomes and spare healthcare expenditure.

关键词： Necrotizing fasciitis Cirrhosis Mortality Septic shock Hospital charges

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Glassy phase and thermodynamics for random field Ising model on spherical lattice in magnetic field

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Chinese Physics B 2010年第10期19卷 525-533页

Phase diagram and thermodynamic parameters of the random field Ising model （RFIM） on spherical lattice are studied by using mean field theory. This lattice is placed in an external magnetic field （B）. The random field （hi） is assumed to be Gaussian distributed with zero mean and a variance （hi2） = HRF2. The free energy （F）, the magnetization （M） and the order parameter （q） are calculated. The ferromagnetic （FM） spin-glass （SG） phase transition is clearly observed. The critical temperature （Tc） is computed under a critical intensity of random field HRF = V/2/πJ. The phase transition from FM to paramagnetic （PM） occurs at TC = J/k in the absence of magnetic field. The critical temperature decreases as HRF increases in the phase boundary of FM-to-SG. The magnetic susceptibility （X） shows a sharp cusp at TC and the specific heat （C） has a singularity in small random field. The internal energy （U） has a similar behaviour to that obtained from the Monte Carlo simulation.

关键词： random field mean field theory magnetization specific heat and phase diagram

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Robust Stabilization of Non-minimum Phase Switched Nonlinear Systems with Uncertainty

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Journal of Systems Science & Complexity 2020年第2期33卷 289-311页

作者： khalil Jouili Laboratory of Advanced Systems Polytechnic School of Tunisia(EPT) B.P.7432078 MarsaTunisia

This paper investigates the problem of robust stabilization of a class of switched nonlinear system with uncertain dynamics where each subsystem represents a non-minimum *** authors first construct a stabilizing sliding mode controller for each subsystem to stabilize individually its own unstable internal ***,a switching strategy is introduced to select the most appropriate diffeomorphism through an infinity of *** conditions are specifically given for the exponential stability and the exponential upper bound of the trajectory of the switched subsystem,which guarantees the global asymptotical stability of the resulting switched ***,the proposed control approach can improvemore the transient state,compared to a feedback linearization based on only one *** studies illustrate the effectiveness of the suggested approach.

关键词： Exponential stability sliding mode control switching control uncertain non-minimum phase systems

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