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Early versus delayed necrosectomy in pancreatic necrosis:A population-based cohort study on readmission,healthcare utilization,and in-hospital mortality

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World Journal of Methodology 2024年第3期14卷 55-67页

作者： Hassam Ali Faisal Inayat Vinay Jahagirdar Fouad Jaber Arslan Afzal Pratik Patel Hamza Tahir Muhammad Sajeel Anwar Attiq Ur Rehman Muhammad Sarfraz Ahtshamullah Chaudhry Gul Nawaz Dushyant Singh Dahiya Amir H sohail Muhammad Aziz Division of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Department of Internal Medicine University of Missouri-Kansas CityKansas CityMO 64108United States Division of Gastroenterology Mather Hospital and Zucker School of Medicine at Hofstra UniversityPort JeffersonNY 11777United States Department of Internal Medicine Jefferson Einstein HospitalPhiladelphiaPA 19141United States Department of Internal Medicine UHS Wilson Medical CenterJohnson CityNY 13790United States Division of Gastroenterology and Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Department of Internal Medicine St.Dominic's HospitalJacksonMS 39216United States Division of Gastroenterology Hepatologyand MotilityThe University of Kansas School of MedicineKansas CityKS 66160United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Division of Gastroenterology and Hepatology The University of ToledoToledoOH 43606United States

BACKGROUND Acute necrotizing pancreatitis is a severe and life-threatening *** poses a considerable challenge for clinicians due to its complex nature and the high risk of *** minimally invasive and open necrosectomy procedures have been *** advancements in treatment modalities,the optimal timing to perform necrosectomy lacks *** To evaluate the impact of necrosectomy timing on patients with pancreatic necrosis in the United *** A national retrospective cohort study was conducted using the 2016-2019 Nationwide Readmissions *** with non-elective admissions for pancreatic necrosis were *** participants were divided into two groups based on the necrosectomy timing:The early group received intervention within 48 hours,whereas the delayed group underwent the procedure after 48 *** various intervention techniques included endoscopic,percutaneous,or surgical *** major outcomes of interest were 30-day readmission rates,healthcare utilization,and inpatient *** A total of 1309 patients with pancreatic necrosis were *** propensity score matching,349 cases treated with early necrosectomy were matched to 375 controls who received delayed *** early cohort had a 30-day readmission rate of 8.6% compared to 4.8%in the delayed cohort(P=0.040).Early necrosectomy had lower rates of mechanical ventilation(2.9%vs 10.9%,P<0.001),septic shock(8%vs 19.5%,P<0.001),and in-hospital mortality(1.1%vs 4.3%,P=0.01).Patients in the early intervention group incurred lower healthcare costs,with median total charges of $52202 compared to$147418 in the delayed *** in the early cohort also had a relatively shorter median length of stay(6 vs 16 days,P<0.001).The timing of necrosectomy did not significantly influence the risk of 30-day readmission,with a hazard ratio of 0.56(95%confidence interval:0.31-1.02,P=0.06).CONCLUSION Our findings show that

关键词： Acute necrotizing pancreatitis Pancreatic necrosis Early necrosectomy Delayed necrosectomy Readmission,Healthcare costs Mortality

Big Data Analytics in Healthcare——A Systematic Literature Review and Roadmap for Practical Implementation

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IEEE/CAA Journal of Automatica Sinica 2021年第1期8卷 1-22页

作者： sohail Imran Tariq Mahmood Ahsan Morshed Timos Sellis the Faculty of Computer Science Karachi Institute of Economics and TechnologyKarachi 75190Pakistan the Faculty of Computer Science Institute of Business AdministrationKarachi 75270Pakistan the School of Engineering and Technology CQ UniversityMelbourne 3000Australia the Data Science Research Institute Swinburne University of TechnologyHawthorn 3122Australia

The advent of healthcare information management systems(HIMSs)continues to produce large volumes of healthcare data for patient care and compliance and regulatory requirements at a global *** of this big data allows for boundless potential outcomes for discovering *** data analytics(BDA)in healthcare can,for instance,help determine causes of diseases,generate effective diagnoses,enhance Qo S guarantees by increasing efficiency of the healthcare delivery and effectiveness and viability of treatments,generate accurate predictions of readmissions,enhance clinical care,and pinpoint opportunities for cost ***,BDA implementations in any domain are generally complicated and resource-intensive with a high failure rate and no roadmap or success strategies to guide the *** this paper,we present a comprehensive roadmap to derive insights from BDA in the healthcare(patient care)domain,based on the results of a systematic literature *** initially determine big data characteristics for healthcare and then review BDA applications to healthcare in academic research focusing particularly on No SQL *** also identify the limitations and challenges of these applications and justify the potential of No SQL databases to address these challenges and further enhance BDA healthcare *** then propose and describe a state-of-the-art BDA architecture called Med-BDA for healthcare domain which solves all current BDA challenges and is based on the latest zeta big data *** also present success strategies to ensure the working of Med-BDA along with outlining the major benefits of BDA applications to ***,we compare our work with other related literature reviews across twelve hallmark features to justify the novelty and importance of our *** aforementioned contributions of our work are collectively unique and clearly present a roadmap for clinical administrators,practitioners and professionals to successf

关键词： Big data analytics(BDA) big data architecture healthcare NoSQL data stores patient care roadmap systematic literature review

A Novel One Pot Synthesis of o-Nitrophenylacetic Acid and Unexpected p-Nitrobenzoic Acid by HNO3-Mediated CHz Extrusion Reaction of Phenylacetic Acid

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Chinese Journal of Chemistry 2012年第2期30卷 353-356页

作者： sohail,Muhammad Raza,Abdul Rauf Ibn-e-Sina Block Department of ChemistryUniversity of SargodhaSargodha 40100Pakistan Department of Applied Chemistry School of Chemical Engineering and EnvironmentBeijing Institute of Technology5 South Zhongguaneun StreetHaidian DistrictBeijing 100081China

The HNO3-mediated commercially important 2-nitrophenylacetic acid. CH2 extrusion reactions product 4-nitrobenzoic of phenylacetic acid lead to acid through the formation one pot synthesis of unexpected of 4-nitropheny... 详细信息

关键词： synthetic methods regioselectivity carboxylic acid aromatic substitution industrial chemistry

Interpretable and Adaptable Early Warning Learning Analytics Model

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Computers, Materials & Continua 2022年第5期71卷 3211-3225页

作者： Shaleeza sohail Atif Alvi Aasia Khanum The University of Newcastle Sydney2000Australia University of Management and Technology Lahore54770Pakistan Forman Christian College Lahore54600Pakistan

Major issues currently restricting the use of learning analytics are the lack of interpretability and adaptability of the machine learning models used in this *** makes it easy for the stakeholders to understand the working of these models and adaptability makes it easy to use the same model for multiple cohorts and courses in educational ***,some models in learning analytics are constructed with the consideration of interpretability but their interpretability is not ***,adaptability is not specifically considered in this *** paper presents a new framework based on hybrid statistical fuzzy theory to overcome these *** also provides explainability in the form of rules describing the reasoning behind a particular *** paper also discusses the system evaluation on a benchmark dataset showing promising *** measure of explainability,fuzzy index,shows that the model is highly *** system achieves more than 82%recall in both the classification and the context adaptation stages.

关键词： Learning analytics interpretable machine learning fuzzy systems early warning interpretability explainable artificial intelligence

Patterns of reproduction in two sympatric gerbil species in arid Egypt

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Integrative Zoology 2009年第2期4卷 248-253页

作者： sohail SOLIMAN Eman M.MOHALLAL Department of Zoology Faculty of ScienceAin Shams UniversityAbbasiyaCairoEgypt Desert Research Centre MatariyaCairoEgypt

Despite a significant number of studies on the reproductive characteristics of small mammals,very little of this work has been conducted on species in ***,the Egyptian greater gerbil(Gerbillus pyramidum Saint-Hilaire,1825)and Anderson’s lesser Egyptian gerbil(Gerbillus andersoni De Winton,1902)in northeastern Egypt were *** behavior in these species was synchronized with rainfall in the winter and spring *** however,the removal of individual gerbils throughout the course of study resulted in an extension of reproductive activity into the dry summer and autumn months in the latter part of the *** results are discussed in the context of density-dependent reproductive behavior in small mammals.

关键词： compensation density dependent Egypt Gerbillus reproduction Sinai.

Fingerprint matching,spoof and liveness detection:classification and literature review

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Frontiers of Computer Science 2021年第1期15卷 179-196页

作者： Syed Farooq ALI Muhammad Aamir KHAN Ahmed sohail ASLAM Department of Software Engineering University of Management and TechnologyLahore 54770Pakistan Department of Informatics and Systems University of Management and TechnologyLahore 54770Pakistan Department of Computer Science University of Management and TechnologyLahore 54770Pakistan

Fingerprint matching,spoof mitigation and liveness detection are the trendiest biometric techniques,mostly because of their stability through life,uniqueness and their least risk of *** recent decade,several techniques are presented to address these challenges over well-known *** study provides a comprehensive review on the fingerprint algorithms and techniques which have been published in the last few *** divides the research on fingerprint into nine different approaches including feature based,fuzzy logic,holistic,image enhancement,latent,conventional machine learning,deep learning,template matching and miscellaneous *** these,deep learning approach has outperformed other approaches and gained significant attention for future *** reviewing fingerprint literature,it is historically divided into four eras based on 106 referred papers and their cumulative citations.

关键词： computer society template matching fingerprint recognition survey deep learning machine learning

Flow of a Jeffery-Six Constant Fluid Between Coaxial Cylinders with Heat Transfer Analysis

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Communications in Theoretical Physics 2011年第8期56卷 345-351页

作者： Muhammad Yousaf Malik Azad Hussain sohail Nadeem Department of Mathematics Quaid-i-Azam University

In the present investigation we have discussed the flow of a Jeffrey-six constant incompressible fluid between two infinite coaxial cylinders in the presence of heat transfer analysis. The governing equations of Jeffrey-six constant fluid along with energy equation have been derived in cylindrical coordinates. The highly nonlinear equations are simplified with the help of non-dimensional parameters and then solved analytically with the help of homotopy analysis method （HAM） for two fundamental flows namely Couette and Generalized Couette flow. The effects of emerging parameters are discussed through graphs. The convergence of the HAM solution has been discussed by plotting h-curves.

关键词： Jeffery-six constant fluid coaxial cylinders heat transfer analysis HAM solutions

Remimazolam for sedation in gastrointestinal endoscopy:A comprehensive review

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World Journal of Gastrointestinal Endoscopy 2024年第7期16卷 385-395页

作者： Dushyant Singh Dahiya Ganesh Kumar Syeda Parsa Manesh Kumar Gangwani Hassam Ali Amir Humza sohail Saqr Alsakarneh Umar Hayat Sheza Malik Yash R Shah Bhanu Siva Mohan Pinnam Sahib Singh Islam Mohamed Adishwar Rao Saurabh Chandan Mohammad Al-Haddad Division of Gastroenterology Hepatology&MotilityThe University of Kansas School of MedicineKansas CityMO 66160United States Department of Internal Medicine Chandka Medical CollegeSindh 77280Pakistan Department of Gastroenterology and Hepatology University of Arkansas For Medical SciencesLittle RockAR 72205United States Division of Gastroenterology Hepatology and NutritionEast Carolina University/Brody School of MedicineGreenvilleNC 27858United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Department of Internal Medicine University of Missouri-Kansas CityKansas CityMO 64108United States Department of Internal Medicine Geisinger Wyoming Valley Medical CenterWilkes BarrePA 18711United States Department of Internal Medicine Rochester General HospitalRochesterNY 14621United States Department of Internal Medicine Trinity Health Oakland/Wayne State UniversityPontiacMI 48341United States Department of Internal Medicine John H.Stroger Hospital of Cook CountyChicagoIL 60612United States Department of Internal Medicine Sinai hospitalBaltimoreMD 21215United States Department of Hepatology University of MissouriColumbiaMO 65211United States Department of Internal Medicine Guthrie Robert Packer HospitalSayrePA 18840United States Division of Gastroenterology and Hepatology Creighton University School of MedicineOmahaNE 68131United States Division of Gastroenterology and Hepatology Indiana University School of MedicineIndianapolisIN 46202United States

Worldwide,a majority of routine endoscopic procedures are performed under some form of sedation to maximize patient ***,benzodiazepines and opioids continue to be widely ***,in recent years,Remimazolam is gaining immense popularity for procedural sedation in gastrointestinal(GI)*** is an ultra-short-acting benzodiazepine sedative which was approved by the Food and Drug Administration in July 2020 for use in procedural *** has shown a favorable pharmacokinetic and pharmacodynamic profile in terms of its non-specific metabolism by tissue esterase,volume of distribution,total body clearance,and negligible drug-drug *** also has satisfactory efficacy and has achieved high rates of successful sedation in GI ***,studies have demonstrated that the efficacy of Remimazolam is non-inferior to Propofol,which is currently a gold standard for procedural sedation in most parts of the ***,the use of Propofol is associated with hemodynamic instability and respiratory *** contrast,Remimazolam has lower incidence of these adverse effects intra-procedurally and hence,may provide a safer alternative to Propofol in procedural *** this comprehensive narrative review,highlight the pharmacologic characteristics,efficacy,and safety of Remimazolam for procedural *** also discuss the potential of Remimazolam as a suitable alternative and how it can shape the future of procedural sedation in gastroenterology.

关键词： Remimazolam Endoscopy Sedation Outcomes Efficacy Safety Pharmacokinetics

Are efforts up to the mark? A cirrhotic state and knowledge about HCV prevalence in general population of Pakistan

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Asian Pacific Journal of Tropical Medicine 2016年第6期9卷 597-598页

作者： Muhammad sohail Afzal Department of Chemistry School of Science University of Management and Technology (UMT)

Pakistan is declared a cirrhotic state by WHO because of high prevalence of Hepatitis C virus(HCV). It is proposed that there are more than 10 million infected individuals in Pakistan. Keeping in mind the scenario, one should expect to have proper surveillance system for HCV monitoring across the country not only for high risk groups but also for general population as well. Monitoring the general population is of considerable help to identify the hot spots for infection spread and will help in designing effective strategies. In this study the current available data from last 6 years is analyzed. The results showed that the range of HCV seroprevalence in general population in Pakistan varied from 3.13%-23.83%. Similarly year wise HCV prevalence showed great variation and the prevalence was 9.57%, 6.04%, 7.46%, 4.9% and 11.04% in 2010, 2011, 2012, 2013 and 2014 respectively. The current analysis declared that available data is not sufficient and is not presenting the original picture of the situation. On these basis, a proper surveillance system is proposed across the country to get an actual picture of the infection for better management in future and massive community education programmes should be warranted in identified hot spots across the country.

关键词： HCV General population Prevalence Community education Pakistan