检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

西藏昌都丁青县孜珠寺藏古籍考察记

古籍保护研究 2024年第2期 103-114页

作者：萨仁高娃王沛白张王建海国家图书馆古籍馆国家古籍保护中心办公室西藏图书馆

2023年5月15日,“古象雄文化遗产调查及抢救性保护研究项目”课题组在西藏丁青县孜珠山(外象雄中心)启动古籍普查及调研座谈活动。本项目由中国经济时报社与国家古籍保护中心合作开展,在“中华古籍保护计划”框架下,对西藏昌都孜珠寺所... 详细信息

2023年5月15日,“古象雄文化遗产调查及抢救性保护研究项目”课题组在西藏丁青县孜珠山(外象雄中心)启动古籍普查及调研座谈活动。本项目由中国经济时报社与国家古籍保护中心合作开展,在“中华古籍保护计划”框架下,对西藏昌都孜珠寺所藏藏文古籍开展调研,旨在深度挖掘古象雄文化遗产的时代价值,探索古籍的文物和文献价值,在古籍普查的基础上进一步做好原生性保护与再生性保护。本文作为“古象雄文化遗产调查及抢救性保护研究项目”成果之一,详尽记录了本次考察的项目背景、考察目的、考察情况,并对文献价值进行评估,提出下一步工作计划。

关键词：西藏古象雄孜珠寺苯教古籍

在线全文

学校读者我要写书评

暂无评论

高台跳水

时代邮刊 2019年第18期 6-7页

作者： wa NA sa(摄) 不详

靛玉红及其类似物抗肿瘤和神经保护作用的研究进展

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中草药 2014年第16期45卷 2404-2411页

作者：王英沙飞陈月华李铭源中药质量研究国家重点实验室澳门大学澳门999078 澳门大学中华医药研究院澳门999078

天然产物靛玉红广泛存在于中药大青叶、青黛、板蓝根中,历史上主要用于治疗白血病。现代药理学研究表明靛玉红是具代表性的细胞周期蛋白依赖性激酶(CDKs)和糖原合成酶激酶-3(GSK-3)抑制剂,对二者的抑制作用均是通过与ATP竞争性靶点结合... 详细信息

天然产物靛玉红广泛存在于中药大青叶、青黛、板蓝根中,历史上主要用于治疗白血病。现代药理学研究表明靛玉红是具代表性的细胞周期蛋白依赖性激酶(CDKs)和糖原合成酶激酶-3(GSK-3)抑制剂,对二者的抑制作用均是通过与ATP竞争性靶点结合。研究发现很多肿瘤和神经退行性疾病会伴随CDKs和GSK-3的异常磷酸化,靛玉红结构上的特点使其对肿瘤和神经退行性疾病具有双重药理活性。因此,靛玉红及其类似物对于同时治疗肿瘤和神经退行性疾病的新型药物开发表现出良好前景。

关键词：靛玉红抗肿瘤神经退行性疾病细胞周期蛋白依赖性激酶糖原合成酶激酶-3

Numerical Simulations of the Performance of Steel Guardrails Under Vehicle impact

在线全文

学校读者我要写书评

暂无评论

Transactions of Tianjin University 2008年第5期14卷 318-323页

作者： haO Hong DEEKS J Andrew WU Chengqing School of Civil and Resource Engineering the University of Western Australia 35 Stirling Highway Crawley WA 6009 Australia School of Civil Environmental and Mining Engineering the University of Adelaide North Terrace SA5005 Australia

Road side barriers are constructed to protect passengers and contain vehicles when a vehicle crashes into a barrier. in general, full-scale crash testing needs to be carried out if a geometrically and structurally equivalent barrier has not previously been proven to meet the requirements of containing the vehicle and dissipating sufficient impact energy for passenger protection. As full-scale crash testing is very expensive, the number of data that can be measured in a test is usually limited, and it may not always be possible to obtain good quality measurements in such a test, a reliable and efficient numerical simulation of crash testing is therefore very useful. This paper presents finite element simulations of a 3-rail steel road traffic barrier under vehicle impact. The performance levels defined in Australian Standards AS5100 Clause 10.5 for these barriers are checked. The numerical simulations show that the barrier is able to meet low performance levels. However, the maximum deceleration is higher than the acceptable limit for passenger protection. if present, a kerb launches the vehicles into the barrier, allowing for the possibility of overriding the barrier under certain circumstances, but it redirects the vehicle and reduces the incident angle, which reduces impact force on the barrier. Further investigation into all common kerb profiles on roads should be carried out, as only one kerb profile is investigated in this study.

关键词： vehicle impact steel barrier kerb performance level vehicle containment passenger protection

在线全文

学校读者我要写书评

暂无评论

海北州草地蝗虫危害监测

青海草业 2010年第2期19卷 39-40,44页

作者：萨仁高娃海北州草原工作站青海西海镇810200

海北州是草地蝗虫灾害频发的地区之一,每年的蝗虫危害面积广、密度高、危害严重。本文从蝗虫的发生数量、危害程度、损失状况等方面进行了详细的调查,并结合实际,对草原蝗虫的生态学特性进行了分析研究,为今后更好的开展草地虫害监测、... 详细信息

海北州是草地蝗虫灾害频发的地区之一,每年的蝗虫危害面积广、密度高、危害严重。本文从蝗虫的发生数量、危害程度、损失状况等方面进行了详细的调查,并结合实际,对草原蝗虫的生态学特性进行了分析研究,为今后更好的开展草地虫害监测、提高预测预报准确率提供了依据。

关键词：海北州草地蝗虫监测

在线全文

学校读者我要写书评

暂无评论

保水剂对牧草种子萌发及生长的影响

青海师范大学学报（自然科学版） 2020年第3期36卷 69-72页

作者：萨仁高娃青海海北藏族自治州草原工作站青海海北810200

采用盆栽试验和田间试验,以冷地早熟禾(Poa crgmophila)、中华羊茅(Festuca Sinensis)、老芒麦(Elymus sibircus L.)、披碱草(Elymus dahuricus) 4种牧草生长为试验材料,分析了五种用量(B1,B2,B3,B4,B5)的保水剂对牧草种子萌发的影响.... 详细信息

采用盆栽试验和田间试验,以冷地早熟禾(Poa crgmophila)、中华羊茅(Festuca Sinensis)、老芒麦(Elymus sibircus L.)、披碱草(Elymus dahuricus) 4种牧草生长为试验材料,分析了五种用量(B1,B2,B3,B4,B5)的保水剂对牧草种子萌发的影响.结果表明,不论是田间试验还是盆栽试验,保水剂都能促进牧草种子生长.盆栽试验条件下,老芒麦牧草种子发芽率在B2(2.0g/kg)水平处理下达到100%.B2处理下,盆栽实验和田间试验条件下的冷地早熟禾和中华羊茅牧草鲜重均为最大值,显著高于其他处理.以上结果表明,保水剂具有提高四种丸粒种子发芽率、鲜重、株高,降低根冠比、提高抗旱性等作用.

关键词：保水剂牧草鲜重

The giant Jiaodong gold province： The key to a unified model for orogenic gold deposits？

在线全文

学校读者我要写书评

暂无评论

Geoscience Frontiers 2016年第3期7卷 409-417页

作者： David i.Groves M.santosh Centre for Exploration Targeting UWA Cmwley 6009 WA Australia Centre for Tectonics Resources and Exploration Department of Earth Sciences University of Adelaicle SA 5005 Australia State Key Laboratory of Geological Processes and Mineral Resources China University of Geosciences Beijing 100083 China Division of interdisciplinary Science Faculty of Science Kochi University Kochi 780-8520 Japan

Although the term orogenic gold deposit has been widely accepted for all gold-only lode-gold deposits,with the exception of Carlin-type deposits and rare intrusion-related gold systems,there has been continuing debate on their *** syngenetic models and hydrothermal models dominated by meteoric fluids are now clearly ***-hydrothermal models fail to explain the genesis of orogenic gold deposits because of the lack of consistent spatially- associated granitic intrusions and inconsistent temporal *** most plausible,and widely accepted,models involve metamorphic fluids,but the source of these fluids is hotly *** within deeper segments of the supracrustal successions hosting the deposits,the underlying continental crust,and subducted oceanic lithosphere and its overlying sediment wedge all have their *** orogenic gold deposits of the giant Jiaodong gold province of China,in the delaminated North China Craton,contain ca.120 Ma gold deposits in Precambrian crust that was metamorphosed over 2000 million years prior to gold *** only realistic source of fluid and gold is a subducted oceanic slab with its overlying sulfide-rich sedimentary package,or the associated mantle *** could be viewed as an exception to a general metamorphic model where orogenic gold has been derived during greenschist- to amphibolite-facies metamorphism of supracrustal rocks：basaltic rocks in the Precambrian and sedimentary rocks in the ***,if a holistic view is taken,Jiaodong can be considered the key orogenic gold province for a unified model in which gold is derived from late-orogenic metamorphic devolatilization of stalled subduction slabs and oceanic sediments throughout Earth *** latter model satisfies all geological,geochronological,isotopic and geochemical constraints but the precise mechanisms of auriferous fluid release,like many other subduction-related processes,are model-driv

关键词： Jiaodong province Orogenic gold Metamorphic fluids Subduction zones Tectonics

Polymethylmethacrylate Coated Alginate Matrix Microcapsules for Controlled Release of Diclofenac Sodium

在线全文

学校读者我要写书评

暂无评论

Pharmacology & Pharmacy 2011年第2期2卷 56-66页

作者： Tapas Pal Shubhajit Paul Biswanath sa 不详

Polymethylmethacrylate (PMMA) coated microcapsules of diclofenac sodium (DFS) were prepared by a modified wa-ter-in-oil-in-water (W1/O/W2) emulsion solvent evaporation method using sodium alginate (saL) as a matrix material in the internal aqueous phase (W1).Their performance with respect to controlled release of the drug in simulated gastric fluid (SGF) and simulated intestinal fluid (SiF) were evaluated, and compared with non-matrix microcapsules prepared by the conventional W1/O/W2 emulsion solvent evaporation method. Scanning electron micrographs (SEM) revealed that all the microcapsules were discrete and spherical in shape;however, the surface porosity of the matrix microcap-sules appeared to be less than that of the non-matrix microcapsules. in case of non-matrix microcapsules, an increase in the volume of water in W1 phase resulted in decrease in the drug entrapment efficiency (DEE) along with increase in release of the drug in both SGF and SiF. While in case of matrix microcapsules increase in the amount of saL in W1 phase and concentration of the coating polymer in organic phase led to increase in DEE of the matrix microcapsules and considerable decrease in the drug release in both SGF and SiF. No interaction between the drug and any of the polymers used to prepare microcapsules was evident from Fourier transform infra-red (FTiR) analysis. The matrix microcapsules prepared using higher concentration of saL and PMMA released the drug following zero order or Case-ii transport model. The matrix microcapsules appeared to be suitable for releasing lesser amounts of DFS in SGF and providing extended release in SiF.

关键词： Polymethylmethacrylate Sodium Alginate Matrix Microcapsules Diclofenac Sodium Drug Release

A scale-integrated exploration model for orogenic gold deposits based on a mineral system approach

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geoscience Frontiers 2020年第3期11卷 719-738页

作者： David i.Groves M.santosh Liang Zhang Orebusters Pty Ltd Gwelup6018WAAustralia State Key Laboratory of Geological Processes and Mineral Resources China University of Geosciences(Beijing)Beijing100083China Dept.of Earth Sciences University of AdelaideSA5005Australia Yonsei Frontier Lab Yonsei UniversitySeoul120-749Republic of Korea

Concept-based orogenic gold exploration requires a scale-integrated approach using a robust mineral system *** genetic hypotheses for orogenic gold deposits that involve near-surface or magmatic-hydrothermal fluids are now negated in terms of a global mineral system *** models involve metamorphic fluids,but the fluid source has been *** metamorphic-fluid models are most widely-accepted but there are serious problems for Archean deposits,and numerous Chinese provinces,including Jiaodong,where the only feasible fluid source is *** all orogenic gold deposits define a coherent mineral system,there are only two realistic sources of fluid and gold,based on their syn-mineralization geodynamic *** are from devolatilization of a subducted oceanic slab with its overlying gold-bearing sulfide-rich sedimentary package,or release from mantle lithosphere that was metasomatized and fertilized during a subduction event,particularly adjacent to craton *** this model,CO_2 is generated during decarbonation and S and ore-related elements released from transformation of pyrite to pyrrhotite at about 500 ℃.This orogenic gold mineral system can be applied to conceptual exploration by first identifying the required settings at geodynamic to deposit *** these settings,it is then possible to define the critical gold mineralization processes in the system:fertility,architecture,and *** geological parameters that define these processes,and the geological,geophysical and geochemical proxies and responses for these critical parameters can then be *** the geodynamic to province scales,critical processes include a tectonic thermal engine and deep,effective,fluid plumbing system driven by seismic swarms up lithosphere-scale faults in an oblique-slip regime during uplift late in the orogenic cycle of a convergent *** the district to deposit scale,the important processes are fluid focussing into regio

关键词： Mineral systems Orogenic gold Sub-crustal fluids Convergent margins Gold exploration