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Prognostic factors for 5-year survival after local excision of rectal cancer

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World Journal of Gastroenterology 2009年第10期15卷 1242-1245页

作者： Dong-Bing Zhao Yong-Kai wu Yong-Fu shao cheng-Feng Wang Jian-Qiang Cai Cancer Institute (Hospital) Chinese Academy of Medical Sciences and Peking UnionMedical College Beijing 100021 China

AIM:To evaluate the prognostic factors for 5-year survival after local excision of rectal cancer,and to examine the therapeutic efficacy and surgical indications for this procedure. METHODS:Clinical data,obtained from 106 local rectal cancer excisions performed between January 1980 and December 2005,were retrospectively *** analysis was performed using the Kaplan-Meier method,statistical comparisons were performed using the log-rank test,and multivariate analysis was performed using the Cox proportional hazards model. RESULTS:Transanal,transsacral,and transvaginal excisions were performed in 92,12,and 2 cases, *** rate of complication,local recurrence, and 5-year survival was 6.6%,17.0%,and 86.7%, *** analysis showed that T stage, vascular invasion,and local recurrence were related to the prognosis of the cases(P<0.05).Multivariate analysis showed that T stage[P=0.011,95% confidence interval(CI)=1.194-3.878]and local recurrence(P=0.022,95%CI=1.194-10.160)were the major prognostic factors for 5-year survival of cases after local excision of rectal cancer. CONCLUSION:Local rectal cancer excision is associated with few complications,and suitable for stages Tis and T1 rectal *** of local recurrence,active postoperative follow-up,and administration of salvage therapy are the effective methods to increase the efficacy of local excision of rectal cancer.

关键词： Rectal cancer Surgery Local excision Recurrence Prognosis

Extract of Naotaifang, a compound Chinese herbal medicine, protects neuron ferroptosis induced by acute cerebral ischemia in rats

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Journal of Integrative Medicine 2020年第4期18卷 344-350页

作者： Bin Lan Jin-wen Ge shao-wu cheng Xi-long Zheng Jun Liao Chao He Zheng-qing Rao Guo-zuo Wang Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases Hunan University of Chinese MedicineChangshaHunan Province 410208China Department of Biochemistry and Molecular Biology The Libin Cardiovascular Institute of AlbertaCumming School of MedicineThe University of CalgaryHealth Sciences CenterCalgaryAlberta T2N4N1Canada

Objective:Our previous research showed that Naotaifang(a compound traditional Chinese herbal medicine)extract(NTE)has clinically beneficial effects on neurological improvement of patients with acute cerebral *** this study,we investigated whether NTE protected acute brain injury in rats and whether its effects on ferroptosis could be linked to the dysfunction of glutathione peroxidase 4(GPX4)and iron ***:We established an acute brain injury model of middle cerebral artery occlusion(MCAO)in rats,in which we could observe the accumulation of iron in neurons,as detected by Perl’s *** assay kits,we measured expression levels of ferroptosis biomarkers,such as iron,glutathione(GSH),reactive oxygen species(ROS)and malonaldehyde(MDA);further the expression levels of transferrin receptor1(TFR1),divalent metal transporter 1(DMT1),solute carrier family 7 member 11(SLC7 A11)and GPX4 were determined using immunohistochemical analysis,real-time quantitative polymerase chain reaction and Western blot ***:We found that treatment with NTE reduced the expression levels of TFR1 and DMT1,reduced ROS,MDA and iron accumulation and reduced neurobehavioral scores,relative to untreated MCAO *** with NTE increased the expression levels of SLC7 A11,GPX4 and GSH,and the number of Nissl bodies in the MCAO ***:Taken together,our data suggest that acute cerebral ischemia induces neuronal ferroptosis and the effects of treating MCAO rats with NTE involved inhibition of ferroptosis through the TFR1/DMT1 and SCL7 A11/GPX4 pathways.

关键词： Ischemic stroke Ferroptosis Naotaifang extract Chinese herbal medicine Iron Glutathione peroxidase 4

Long Dan Xie Gan Formula Granule Promotes Pro-Inflammatory Cytokine Expression in Female Guinea Pigs with Recurrent Genital Herpes

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Digital Chinese Medicine 2018年第2期1卷 164-172页

作者： Lin KUANG En-Hui HUANG Qing-Hu HE shao-wu cheng Xiao-Dan LIU Hunan University of Chinese Medicine ChangshaHunan 410208China

Objective To explore the effects of Long Dan Xie Gan formula granule(LDXGFG)on regulation of pro-inflammatory cytokines in female guinea pigs with recurrent genital herpes(herpes simplex virus 2,HSV-2).Methods Levels of pro-inflammatory cytokines in blood of HSV-2-infected guinea pigs,including IL-6,IL-8,IL-10,IL-12,IFN-α,IFN-β,IFN-γ,and TNF-α,were detected by ELISA;corresponding gene expression levels in tissues were detected by real-time *** IL-6,IL-10,IL-12,IFN-α,IFN-γand TNF-αdecreased significantly in both blood and diseased tissues after infection with recurrent genital *** feeding LDXGFG to HSV-2-infected guinea pigs,IL-6,IL-10,IL-12,IFN-α,IFN-γand TNF-αdemonstrated significant increases,similar to the effects of acyclovir(ACV).LDXGFG promoted the expression of pro-inflammatory cytokines in blood and tissue,with a stronger effect than ***,LDXGFG demonstrated broader effects than *** The present results suggest that LDXGFG can serve as an alternative,inexpensive,and long-term treatment for HSV-2 infection.

关键词： Recurrent genital herpes HSV-2 Long Dan Xie Gan formula granule(LDXGFG) Pro-inflammatory cytokines ACV Guinea pig

A mild, configurable, flexible CoNi-LDH（v）/Zn battery based on H-vacancy-induced reversible Zn2+ intercalation

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Journal of Energy Chemistry 2025年第1期100卷 498-508页

作者： Xinyue cheng Dingsheng wu Hao Gao Qingqing Wang Pengfei Lv Sam S.Yoon Qufu Wei Key Laboratory of Eco-textiles Ministry of Education Jiangnan University School of Mechanical Engineering Korea University

Flexible Zn-based batteries have attracted increasing research interest as essential components of wearable energy storage ***,the advancement of flexible aqueous Zn-based batteries based on Co-Ni layered double hydroxide （CoNi-LDH） as the cathode material is hampered by their poor cycling stability and the corrosiveness of alkaline ***,CoNi-LDH nanosheets enriched with H vacancies (CoNi-LDH（v）) were constructed on a flexible carbon cloth （CC） substrate via electrochemical deposition and *** Zn-based battery comprising CoNi-LDH（v）@CC as the cathode exhibited highly reversible conversion reactions and stable operation in 3 M ZnSO4electrolyte （pH=4）.The battery delivered an excellent specific capacity (225 mA h g-1,0.26 mA h cm-2),acceptable cycling stability（53.9%,900 cycles）,and high discharging *** abundant H vacancies served as active sites for the reversible intercalation of Zn2+and the extravasation of NO3-generated channels and space for Zn2+transport and storage,together enabling an excellent Zn2+storage ***,a sandwich-structured solid-state CoNi-LDH（v）@CC//Zn@CC battery was fabricated and was found to exhibit a noteworthy electrochemical performance and mechanical *** a proof of concept,the unencapsulated battery powered a digital watch under various deformation conditions and operated stably for 80 ***,the flexible battery displayed outstanding customizability,maintaining an open-circuit voltage of 1.42 V even after being cut *** proposed engineering strategy contributes to the realization of textiles with truly wearable energy-storage devices.

关键词： CoNi/Zn battery H vacancies Mild aqueous electrolyte Tailorable battery Wearable energy storage device

浅谈民族地区提高建筑项目经济效益的有效途径——以大湘西为例

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湖南农机 2014年第1期 101-102页

作者：吴绍成湘西民族职业技术学院湖南吉首416000

文章针对民族地区建筑项目市场的特点,结合自身从事该行业的实践经验,分析和探讨如何提高建筑项目经济管理的方式方法。

关键词：民族地区建筑项目经济效益

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基于Agent技术的通信规约接口设计

电网技术 2006年第10期30卷 100-104页

作者：伍少成朱学峰骆华华南理工大学自动化科学与工程学院广东省广州市510640 广东电网公司东莞供电局广东省东莞市511700

提出了基于Multi-Agent技术的规约接口设计框架, 采用产生式规则知识表示方法将通信规约标准表示为 Agent能理解的通信规约规则库,然后将该规则库转变为规约Agent的内部状态转移规则库,从而达到了实现规约标准的目的。使用该规约接口可... 详细信息

提出了基于Multi-Agent技术的规约接口设计框架, 采用产生式规则知识表示方法将通信规约标准表示为 Agent能理解的通信规约规则库,然后将该规则库转变为规约Agent的内部状态转移规则库,从而达到了实现规约标准的目的。使用该规约接口可以在不修改源程序的情况下增加或修改通信规约标准,因此减少了维护通信规约的工作量。

关键词： Agent技术通信规约产生式规则知识查询与操作语言

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厂站电能量采集终端测试系统的研制

电力系统保护与控制 2009年第13期37卷 83-87页

作者：伍少成周尚礼张亚东肖勇广东电网公司电力科学研究院广东广州510600

近几年来,全国各省正在大力推进电能量计量遥测系统的建设,其中通信规约调试和终端功能测试是系统建设中一项非常重要而又费时费力的工作。针对电能计量遥测系统建设的需求研制了电能量采集终端测试系统,系统由测试通信通道装置和测试... 详细信息

近几年来,全国各省正在大力推进电能量计量遥测系统的建设,其中通信规约调试和终端功能测试是系统建设中一项非常重要而又费时费力的工作。针对电能计量遥测系统建设的需求研制了电能量采集终端测试系统,系统由测试通信通道装置和测试主站组成,不但可以作为调试通信规约的工具,也是终端产品验收的测试平台。该系统投入使用后,大大提高了测试工作效率,为广东地区电网电能计量遥测系统建设顺利推进发挥了重要的作用。

关键词： IEC102标准计量遥测系统电能量采集终端测试系统

Identifying the dynamic behaviors in complete reconstruction of Co-based complex precatalysts during electrocatalytic oxygen evolution

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Journal of Energy Chemistry 2025年第1期100卷 226-233页

作者： Jingfang Zhang Danyang wu Linke Cai Youluan Lu Fanpeng cheng Lijuan Shi Qun Yi Yao Liu Yi Huang Key Laboratory of Green Chemical Engineering Process of Ministry of Education Engineering Research Center of Phosphorus Resources Development and Utilization of Ministry of Education Hubei Key Laboratory of Novel Reactor and Green Chemical Technology School of Chemical Engineering & Pharmacy Wuhan Institute of Technology Key Laboratory of Pesticide & Chemical Biology of Ministry of Education Engineering Research Center of Photoenergy Utilization for Pollution Control and Carbon Reduction of Ministry of Education College of Chemistry Central China Normal University College of Materials Science and Engineering Fuzhou University

Transition metal-based nanomaterials have emerged as promising electrocatalysts for oxygen evolution reaction（OER）. Considerable research efforts have shown that self-reconstruction occurs on these nanomaterials under operating conditions of OER process. However, most of them undergo incomplete reconstruction with limited thickness of reconstruction layer, leading to low component utilization and arduous exploration of real catalytic mechanism. Herein, we identify the dynamic behaviors in complete reconstruction of Co-based complexes during OER. The hollow phytic acid（PA） cross-linked CoFe-based complex nanoboxes with porous nanowalls are designed because of their good electrolyte penetration and mass transport ability, in favor of the fast and complete reconstruction. A series of experiment characterizations demonstrate that the reconstruction process includes the fast substitution of PA by OH-to form Co（Fe）(OH)xand subsequent potential-driven oxidation to Co（Fe）OOH. The obtained CoFeOOH delivers a low overpotential of 290 mV at a current density of 10 mA cm-2and a long-term *** experiment results together with theory calculations reveal that the Fe incorporation can result in the electron rearrangement of reconstructed CoFeOOH and optimization of their electronic structure,accounting for the enhanced OER activity. The work provides new insights into complete reconstruction of metal-based complexes during OER and offers guidelines for rational design of high-performance electrocatalysts.

关键词： Complete reconstruction Co-based complex Precatalysts Oxygen evolution reaction

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一种改进的电力通信协议优化方法与应用

沈阳工业大学学报 2022年第6期44卷 607-612页

作者：梁洪浩伍少成王波刘洋李鹏中国南方电网有限公司深圳供电局广东深圳518000

针对智能电力通信网络存在的数据不兼容的问题,提出了一种基于DLT_645的Modbus/TCP通信协议.通过分析电力通信网的功率计算方法,讨论智能电网的交互需求,并按照需求分析结果制定智能电表与采集终端之间的数据传输策略,同时给出了该协议... 详细信息

针对智能电力通信网络存在的数据不兼容的问题,提出了一种基于DLT_645的Modbus/TCP通信协议.通过分析电力通信网的功率计算方法,讨论智能电网的交互需求,并按照需求分析结果制定智能电表与采集终端之间的数据传输策略,同时给出了该协议网络接口的硬件设计.仿真测试结果表明,与常用的Modbus/RTU协议相比,该改进的Modbus/TCP协议具有更低的平均响应时间、更快的执行速度和较高的数据传输成功率.

关键词：智能电网通信需求数据采集采集终端智能电表网络接口 Modbus/TCP协议 DLT_645协议