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Global-local combined features to detect pain intensity from facial expression images with attention mechanism

Journal of Electronic Science and Technology 2024年第3期22卷 80-93页

作者： Jiang wu Yi Shi Shun Yan hong-Mei Yan Yangtze Delta Region Institute(Huzhou) University of Electronic Science and Technology of ChinaHuzhou313001China MOE Key Laboratory for Neuroinformation School of Life Science and TechnologyUniversity of Electronic Science and Technology of ChinaChengdu611731China College of Engineering University of California at Santa BarbaraSanta Barbara93106USA

The estimation of pain intensity is critical for medical diagnosis and treatment of *** the development of image monitoring technology and artificial intelligence,automatic pain assessment based on facial expression and behavioral analysis shows a potential value in clinical *** paper reports a framework of convolutional neural network with global and local attention mechanism(GLA-CNN)for the effective detection of pain intensity at four-level thresholds using facial expression ***-CNN includes two modules,namely global attention network(GANet)and local attention network(LANet).LANet is responsible for extracting representative local patch features of faces,while GANet extracts whole facial features to compensate for the ignored correlative features between *** the end,the global correlational and local subtle features are fused for the final estimation of pain *** under the UNBC-McMaster Shoulder Pain database demonstrate that GLA-CNN outperforms other state-of-the-art ***,a visualization analysis is conducted to present the feature map of GLA-CNN,intuitively showing that it can extract not only local pain features but also global correlative facial *** study demonstrates that pain assessment based on facial expression is a non-invasive and feasible method,and can be employed as an auxiliary pain assessment tool in clinical practice.

关键词： Attention Convolutional neural network Facial expression Pain intensity

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Dynamical switchable quantum nonreciprocity induced by off-resonant chiral two-photon driving

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Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 31-37页

作者： Da-Wei Liu Zi-Hao Li Shi-Lei Chao Ying wu Liu-gang Si School of Physics and Institute for Quantum Science and Engineering Huazhong University of Science and TechnologyWuhan 430074China

Optical nonreciprocity,which refers to the direction-dependent emission,scattering and absorption of photons,plays a very important role in quantum engineering and quantum information ***,we propose an all-optical approach to achieve the optical dynamical switchable quantum nonreciprocity by an off-resonant chiral two-photon driving in a single microring cavity,which differs from the conventional nonreciprocal *** is shown that the optical field with time-dependent statistical properties can be generated and the nonreciprocity flips periodically,with switchable photon blockade and photon-induced tunneling *** find that the dynamical system is robust and immune to the parameter variations,which loosens the parameter range of ***,the time window for one-way quantum information is sufficiently wide and *** work opens a new idea for the current quantum nonreciprocal research,which can facilitate a memory functionality and be used for future inmemory superconducting quantum *** other nonreciprocal quantum devices,i.e.,dynamical switchable nonreciprocal squeezing and entanglement,may be inspired by our method,which is expected to have important applications in future quantum technology.

关键词： dynamical switchable nonreciprocity single-photon source chiral two-photon driving

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土质边坡微型桩组合结构大型振动台试验研究

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岩土力学 2019年第10期40卷 3844-3854页

作者：吴红刚武志信谢显龙牌立芳中铁西北科学研究院有限公司甘肃兰州730070 中铁西北科学研究院有限公司滑坡工程实验室甘肃兰州730070 中铁西北科学研究院有限公司西部环境岩土及场地修复技术工程实验室甘肃兰州730070 兰州交通大学土木工程学院甘肃兰州730070 西南交通大学地球科学与工程学院四川成都611756

我国是一个地震多发国家。微型桩组合结构作为一种新型柔性支护结构,研究其在地震作用下对土质边坡的支护作用成为了一个意义重大的问题。为此,通过大型振动台试验,以混合加载的方式,研究了微型桩组合结构在加固土质边坡中的动力学特性... 详细信息

我国是一个地震多发国家。微型桩组合结构作为一种新型柔性支护结构,研究其在地震作用下对土质边坡的支护作用成为了一个意义重大的问题。为此,通过大型振动台试验,以混合加载的方式,研究了微型桩组合结构在加固土质边坡中的动力学特性。试验结果表明:微型桩组合结构在地震作用下对土质边坡的加固达到了理想的结果;加载时随着El波加速度峰值的不断增大,前、后排微型桩桩身加速度峰值及桩身动土压力随之不断增大;随着输入的El-Centro波动峰值加速度的增大,测点动土压力响应效应也越显著;微型桩滑面上、下1/3位置、悬臂端顶部及锚固段底部处,动土压力及加速度常常达到最大值,在实际工程设计及应用中应重点关注这些位置。该研究结果可以为同类地区治理类似滑坡提供抗震设计支撑。

关键词：土质边坡大型振动台试验微型桩地震作用地震动土压力地震加速度峰值

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PDE滤波原理与方法

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振动与冲击 2010年第10期29卷 232-235页

作者：尹爱军吴宏钢秦树人重庆大学机械传动国家重点实验室重庆大学机械学院测试中心重庆400044 重庆通信学院信息工程系重庆400035

通过对偏微分方程(Partial differential equation,PDE)基本理论的研究;分析了PDE滤波的基本原理,从理论上探讨了PDE滤波与传统滤波器的相关性;并从传统滤波器的角度出发,解决了PDE滤波的演化时间、迭代次数、调节系数等参数设计问题;... 详细信息

通过对偏微分方程(Partial differential equation,PDE)基本理论的研究;分析了PDE滤波的基本原理,从理论上探讨了PDE滤波与传统滤波器的相关性;并从传统滤波器的角度出发,解决了PDE滤波的演化时间、迭代次数、调节系数等参数设计问题;分析了PDE滤波的影响因素;采用基本差分格式建立了PDE滤波的迭代式。实验结果表明,PDE滤波方法可有效消除振动信号中的噪声干扰,且去噪之后信号畸变少,同时保持了信号的边缘特性和内部连续性。

关键词：偏微分方程滤波原理方法

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双排桩治理大型多滑动面滑坡的振动台试验

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铁道工程学报 2015年第11期32卷 30-36页

作者：吴红刚冯文强中铁西北科学研究院有限公司兰州730000

研究目的:随着国内高速公路、铁路及民航等工程建设步伐的不断加快,在我国西部高烈度地震区出现了很多推力巨大的工程滑坡,往往具有多层、多级的显著特征,双排抗滑桩是治理该类大型滑坡的有效措施。结合青海玉树机场路滑坡、四川攀枝花... 详细信息

研究目的:随着国内高速公路、铁路及民航等工程建设步伐的不断加快,在我国西部高烈度地震区出现了很多推力巨大的工程滑坡,往往具有多层、多级的显著特征,双排抗滑桩是治理该类大型滑坡的有效措施。结合青海玉树机场路滑坡、四川攀枝花机场滑坡等典型实例,采用大型振动台模型试验,分X、Z和XZ三类加载工况研究双排抗滑桩治理大型多滑动面滑坡的动力响应和坡体变形破坏特征。研究结论:(1)试验表明双排桩治理大型多滑动面滑坡的效果明显,体现了"大震不倒"的设计理念;(2)试验过程中,坡体整体变形以拉剪破坏为主,坡体后部平台以震陷为主,滑体分层前倾,接触面效应明显,滑面逐步向深层发展,模型箱两侧加持作用显著;(3)测试数据分析表明,前、后排桩荷载分担不均,后排桩承担大部分滑坡推力(主要来源于深层滑体的滑坡推力),前排桩承担滑坡推力比例较小;(4)本项研究对双排桩的动力学性能分析有着理论和实际意义。

关键词：双排抗滑桩多滑动面滑坡振动台试验滑坡推力

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A Prediction Model for Detecting Dysthyroid Optic Neuropathy Based on Clinical Factors and Imaging Markers of the Optic Nerve and Cerebrospinal Fluid in the Optic Nerve Sheath

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当代医学科学（英文） 2024年第4期44卷 827-832页

作者： hong-yu wu Ban LUO gang YUAN Qiu-xia WANG Ping LIU Ya-li ZHAO Lin-han ZHAI Wen-zhi LV Jing ZHANG Lang CHEN Department of Radiology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Ophthalmology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Endocrinology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Medical Imaging Guangdong Second Provincial General HospitalGuangzhou 510317China Department of Radiology Sir Run Run Shaw Hospital Affiliated with the School of Medicine of Zhejiang UniversityHangzhou 310000China Department of Artificial Intelligence Julei Technology CompanyWuhan 430030China

Objective:This study aimed to develop and test a model for predicting dysthyroid optic neuropathy(DON)based on clinical factors and imaging markers of the optic nerve and cerebrospinal fluid(CSF)in the optic nerve ***:This retrospective study included patients with thyroid-associated ophthalmopathy(TAO)without DON and patients with TAO accompanied by DON at our *** imaging markers of the optic nerve and CSF in the optic nerve sheath were measured on the water-fat images of each patient and,together with clinical factors,were screened by Least absolute shrinkage and selection ***,we constructed a prediction model using multivariate logistic *** accuracy of the model was verified using receiver operating characteristic curve ***:In total,80 orbits from 44 DON patients and 90 orbits from 45 TAO patients were included in our *** variables(optic nerve subarachnoid space and the volume of the CSF in the optic nerve sheath)were found to be independent predictive factors and were included in the prediction *** the development cohort,the mean area under the curve(AUC)was 0.994,with a sensitivity of 0.944,specificity of 0.967,and accuracy of ***,in the validation cohort,the AUC was 0.960,the sensitivity was 0.889,the specificity was 0.893,and the accuracy was ***:A combined model was developed using imaging data of the optic nerve and CSF in the optic nerve sheath,serving as a noninvasive potential tool to predict DON.

关键词： dysthyroid optic neuropathy magnetic resonance imaging optic nerve optic nerve subarachnoid space water-fat sequence

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玄武岩纤维增强复合材料在高边坡防护中的振动台试验研究

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岩土力学 2021年第2期42卷 390-400页

作者：赖天文雷浩武志信吴红刚兰州交通大学土木工程学院甘肃兰州730070 中铁西北科学研究院有限公司甘肃兰州730030 甘肃省交通规划勘察设计院股份有限公司甘肃兰州730070

在地震烈度较低时,钢锚索可以很好地限制坡体变形,起到良好的边坡支护效果。但是在强震条件下,常规的锚索难以发挥其锚固作用,最终导致锚固失效破坏,常会引发边坡失稳破坏的现象,且在地下水等腐蚀性物质的作用下,常会造成钢锚索的锈蚀... 详细信息

在地震烈度较低时,钢锚索可以很好地限制坡体变形,起到良好的边坡支护效果。但是在强震条件下,常规的锚索难以发挥其锚固作用,最终导致锚固失效破坏,常会引发边坡失稳破坏的现象,且在地下水等腐蚀性物质的作用下,常会造成钢锚索的锈蚀问题。鉴于此,通过大型振动台试验,对新型玄武岩纤维增强复合材料(basalt fiber reinforced plastics,简称BFRP)加固边坡及无支护边坡的动力响应进行了对比研究,旨在为高边坡加固中BFRP锚索的动力合理性设计提供科学依据。研究结果表明:相较于BFRP锚索支护边坡而言,无支护边坡在地震波加载过程中具有明显的变形阶段,主要可划分为弹性阶段、塑性阶段、塑性增强阶段以及破坏阶段,且当输入波峰值小于0.2g时,BFRP锚索支护边坡与无支护边坡均可处于弹性状态;BFRP锚索支护边坡的加速度峰值均要大于无支护边坡的加速度峰值,表明相较于无支护边坡而言,BFRP锚索可有效提高边坡的刚度;同一工况的地震波作用下,无支护边坡中各测点位移谱值均要大于BFRP锚索支护边坡对应测点的位移谱值,表明BFRP锚索用于边坡支护工程中时,可以很好地限制坡体变形,有利于提高坡体的抗震性能。

关键词：高边坡振动台试验 BFRP锚索加速度位移谱

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Paroxysmal Kinesigenic Dyskinesia:Genetics and Pathophysiological Mechanisms

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Neuroscience Bulletin 2024年第7期40卷 952-962页

作者： Jiao-Jiao Xu hong-Fu Li Zhi-Ying wu Department of Medical Genetics and Center for Rare Diseases The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Department of Neurology in the Second Affiliated Hospital Key Laboratory of Medical Neurobiology of Zhejiang ProvinceZhejiang University School of MedicineHangzhou 310009China

Paroxysmal kinesigenic dyskinesia(PKD),the most common type of paroxysmal movement disorder,is characterized by sudden and brief attacks of choreoathetosis or dystonia triggered by sudden voluntary *** is mainly caused by mutations in the PRRT2 or TMEM151A *** exact pathophysiological mechanisms of PKD remain unclear,although the function of PRRT2 protein has been well characterized in the last *** on abnormal ion channels and disturbed synaptic transmission in the absence of PRRT2,PKD may be channelopathy or synaptopathy,or *** addition,the cerebellum is regarded as the key pathogenic *** depolarization in the cerebellum is tightly associated with dyskinetic ***,in PKD,other than the cerebellum,the role of the cerebrum including the cortex and thalamus needs to be further investigated.

关键词： Paroxysmal kinesigenic dyskinesia PRRT2 TMEM151A Genetics Pathophysiological mechanisms

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Designed imidazole-based supramolecular catalysts for accelerating oxidation/hydrolysis cascade reactions

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Nano Research 2024年第6期17卷 4916-4923页

作者： Yuanxi Liu Wenjie Xu Shichao Xu Haifeng wu Baoli Zhang Li Song Zhen-gang Wang State Key Laboratory of Organic-Inorganic Composites Key Lab of Biomedical Materials of Natural Macromolecules(Ministry of Education)Beijing Laboratory of Biomedical MaterialsCollege of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029China National Synchrotron Radiation Laboratory CAS Center for Excellence in NanoscienceUniversity of Science and Technology of ChinaHefei 230029China

Reconstructing enzymatic active sites presents a significant challenge due to the intricacies involved in achieving enzyme-like scaffold folding and spatial arrangement of essential functional *** is also a growing interest in building biocatalytic networks,wherein multiple enzymatic active sites are localized within a single artificial system,allowing for cascaded *** this work,we report the self-assembly of imidazole or its derivatives with fluorenylmethyloxycarbonyl-modified histidine and Cu2+to fabricate a supramolecular catalyst,which possesses catechol oxidase-like dicopper center with multiple imidazole as the coordination *** electron microscopy,low-temperature X-band continuous-wave electron paramagnetic resonance,K-edge X-ray absorption spectra/the extended X-ray absorption fine structure analysis,and density functional theory modeling were used for the structural characterization of the *** phenol derivatives and the dissolved oxygen were used as the substrates,with the addition of 4-aminoantipyrine to generate a red adduct with a maximum absorbance at 510 nm,for obtaining time-dependent absorbance change curves and estimating the *** results reveal that the addition of imidazole synergistically accelerates the oxidative activity about 10-fold and the hydrolysis activity about 14-fold than fluorenylmethyloxycarbonyl modified-histidine/Cu2+.The supramolecular nanoassembly also exhibits the ability to catalyze oxidation/hydrolysis cascade reactions,converting 2′,7′-dichlorofluorescin diacetate into 2′,7′-*** process can be regulated through the methylation of the imidazole component at various *** work may contribute to the design of advanced biomimetic catalysts,and shed light on early structural models of the active sites of the primitive copper-dependent enzymes.

关键词： enzyme mimic self-assembly supramolecular catalyst cascade reactions

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Predicting submerged vegetation drag with a machine learning-based method

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Journal of Hydrodynamics 2024年第3期36卷 534-545页

作者： Meng-yang Liu hong-wu Tang Sai-yu Yuan Jing Yan College of Water Conservancy and Hydropower Engineering Hohai UniversityNanjing210098China Key Laboratory of Hydrologic-Cycle and Hydrodynamic-System of Ministry of Water Resources Hohai UniversityNanjing210098China

Accurate estimation of the drag forces generated by vegetation stems is crucial for the comprehensive assessment of the impact of aquatic vegetation on hydrodynamic processes in aquatic *** coupling relationship between vegetation layer flow velocity and vegetation drag makes precise prediction of submerged vegetation drag forces particularly *** present study utilized published data on submerged vegetation drag force measurements and employed a genetic programming(GP)algorithm,a machine learning technique,to establish the connection between submerged vegetation drag forces and flow and vegetation *** using the bulk velocity,U,as the reference velocity scale to define the drag coefficient,C_(d),and stem Reynolds number,the GP runs revealed that the drag coefficient of submerged vegetation is related to submergence ratio(H^(*)),aspect ratio(d^(*)),blockage ratio(ψ^(*)),and vegetation density(λ).The relation between vegetation stem drag forces and flow velocity is implicitly embedded in the definition of C_(d).Comparisons with experimental drag force measurements indicate that using the bulk velocity as the reference velocity,as opposed to using the vegetation layer average velocity,U_(v),eliminates the need for complex iterative processes to estimate U_(v)and avoids introducing additional errors associated with U_(v)*** approach significantly enhances the model’s predictive capabilities and results in a simpler and more user-friendly formula expression.

关键词： Drag coefficient genetic programming algorithm submerged vegetation flow resistance cylinder array

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