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母体携带HCMV-DNA对母乳喂养HCMV感染患儿生长发育与细胞免疫和体液免疫的影响

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中华医院感染学杂志 2024年第7期34卷 1086-1090页

作者：陈玉李莉吴伟伟陈震张海涛山东省泰安市妇幼保健院新生儿科山东泰安271000

目的探讨母体携带人巨细胞病毒(HCMV)-DNA对母乳喂养HCMV感染患儿生长发育、细胞免疫和体液免疫的影响。方法选择2022年1月-2023年1月山东省泰安市妇幼保健院新生儿科收治的145例母乳喂养HCMV感染患儿为研究对象,根据患儿母亲的母乳中HC... 详细信息

目的探讨母体携带人巨细胞病毒(HCMV)-DNA对母乳喂养HCMV感染患儿生长发育、细胞免疫和体液免疫的影响。方法选择2022年1月-2023年1月山东省泰安市妇幼保健院新生儿科收治的145例母乳喂养HCMV感染患儿为研究对象,根据患儿母亲的母乳中HCMV-DNA是否为阳性分为阳性组(n=82)和阴性组(n=63)。采用实时荧光定量聚合酶链式反应(PCR)检测患儿尿液及母乳中HCMV-DNA含量。入院时,由儿科医师测量并记录患儿头围、身高和体质量。采用Gesell发育量表评估患儿发育商(DQ);采用耳声发射听力(DPOA)检查患儿听力;采用新生儿20项行为神经测定量表(NBNA)评价神经发育。采用流式细胞仪检测T淋巴细胞亚群,采用免疫比浊法检测免疫球蛋白。结果阳性组和阴性组母乳喂养HCMV感染患儿头围、身高、体质量、DQ值、NBNA值、DPOA、CD_(3)^(+)、CD_(4)^(+)、CD_(8)^(+)、CD_(4)^(+)/CD_(8)^(+)、免疫球蛋白(Ig)G、IgA、IgM比较,均差异无统计学意义。结论母体携带HCMV-DNA对母乳喂养HCMV感染患儿生长发育和免疫功能的影响不显著。

关键词：人巨细胞病毒母乳喂养感染生长发育细胞免疫体液免疫

Using a Surgeon-modified Iliac Branch Device to Preserve the Internal Iliac Artery during Endovascular Aneurysm Repair： Single-center Experiences and Early Results

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Chinese Medical Journal 2015年第5期128卷 674-679页

作者： wei-wei wu Chen Lin Bao Liu Chang-wei Liu Department of VascuLar Surgery Beijing Tsinghua Changgung Hospital Medical Center lsinghua University Beijing 102218 China Department of Vascular Surgery Peking Union Medical College Hospital Chinese Academy of Medical Science Beijing 100730 China

Background：To evaluate the feasibility of a new surgeon-modified iliac branch device （IBD） technique to maintain pelvic perfusion in the management of common iliac artery （CIA） aneurysm during endovascular aneurysm repair （EVAR）.Methods：From January 2011 to December 2013,a new surgeon-modified IBD technique was performed in department of vascular surgery of Peking Union Medical College Hospital in five patients treated for CIA aneurysm with or without abdominal aortic aneurysm.A stent-graft limb was initially deployed in vitro,anastomosed with vascular graft,creating a modified IBD reloaded into a larger sheath,with or without a guidewire preloaded into the side *** reloaded IBD was then placed in the iliac artery,with a covered stent bridging internal iliac artery and the ***,a bifurcated stent-graft was deployed,and a limb device was used to connect the main body and ***：Technical successes were obtained in all *** mean follow-up length was 24 months （range：6-38 months）.All grafts remained patent without any sign of *** were no aneurysm ruptures,deaths,or other complications related to pelvic ***：Using the surgeon-modified IBD to preserve pelvic flow is a feasible endovascular technique and an appealing solution for personalized treatment of CIA aneurysm during EVAR.

关键词： Abdominal Aortic Aneurysm Common lliac Artery Aneurysm Endovascular Repair Internal lliac Artery Modified Iliac Branch Device

长江中游港口的时空演变与预测——对湖南省城陵矶港的启示

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岳阳职业技术学院学报 2024年第3期39卷 55-60页

作者：刘雅婷田小勇吴微伟湖南理工学院经济与管理学院湖南岳阳414000

本文采用标准差椭圆、重心模型和赫芬达尔—赫希曼指数研究1998—2021年间长江中游集装箱港口的时空演变特征,同时使用线性预测方法对2025—2035年该地区港口集装箱吞吐量进行预测。研究结果表明:赫芬达尔—赫希曼指数在总体上虽有所下... 详细信息

本文采用标准差椭圆、重心模型和赫芬达尔—赫希曼指数研究1998—2021年间长江中游集装箱港口的时空演变特征,同时使用线性预测方法对2025—2035年该地区港口集装箱吞吐量进行预测。研究结果表明:赫芬达尔—赫希曼指数在总体上虽有所下降,但市场结构整体上仍处于高寡占Ⅱ型,说明长江中游地区内的集装箱港口分布更加均衡并趋于分散化;长江中游港口的集装箱吞吐量重心在江西省境内,重心轨迹呈现出自东北向西南,再自东南向西北移动的趋势,标准差椭圆的主要分布态势呈现由东北至西南的分布;长江中游港口的集装箱吞吐量呈稳步增长趋势,预测在2035年能达到752万标准箱。本研究能对长江中游集装箱港口提升自身竞争力提供数据参考,以更好发挥港口的辐射带动作用,推动区域港口群协同发展。

关键词：长江中游地区集装箱港口赫芬达尔—赫希曼指数标准差椭圆

ON NECESSITY OF PLACING AN AERATOR IN THE BOTTOM DISCHARGE TUNNEL AT THE LONGTAN HYDROPOWER STATION

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Journal of Hydrodynamics 2006年第6期18卷 698-701页

作者： wu Jian-hua wu wei-wei RUAN Shi-ping College of Water Conservancy and Hydropower Engineering Hohai University Nanjing 210098 China

The air entrainment for avoiding cavitation damage has been widely used in long free flow tunnels. It is crucial to determine whether an aerator is needed for shorter tunnels. In this article, the bottom discharge tunnel at the Longtan Hydropower Station was involved, for which the free flow tunnel section was only 50.00 m long. The cavitation in the tunnel with and without the aerator was investigated using the physical models of the scale 1/30, through the measurements of cavitation noise. The experimental results show that it is necessary to place the aerator at the inlet of the free flow section for higher reservoir level to protect this tunnel from cavitation damage.

关键词： aerator bottom discharge tunnel cavitation damage cavitation noise Longtan Hydropower Station

HYDRAULIC RESEARCH OF AERATORS ON TUNNEL SPILLWAYS

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Journal of Hydrodynamics 2007年第3期19卷 330-334页

作者： RUAN Shi-ping wu Jian-hua wu wei-wei XI Ru-ze College of Water Conservancy and Hydropower Engineering Hohai University Nanjing 210098 China Anhui Institute of Hydraulic Research Bengbu 233000 China

The selection of the configuration and size of an aerator was of importance for a tunnel spillway under the conditions of high speed flows. Experimental investigations were conducted on the effects of entrained air on the tunnel spillway in the Goupitan Project, based on the criterion of gravity similarity and the condition of aerated flow velocity of over 6 m/s, with physical models. The configurations of the aerators were presented of a larger bottom air concentration, to protect the tunnel spillway from cavitation as well as to see no water fills in the grooves.

关键词： cavitation aerator air concentration tunnel spillway the Goupitan Project

重症监护病房压力性损伤患者伤口感染的致病菌及危险因素分析

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局解手术学杂志 2024年第5期33卷 428-431页

作者：王洁吴炜炜林一禾南京中医药大学附属南京市中西医结合医院EICU 江苏南京210014

目的探讨重症监护病房压力性损伤(PI)患者的伤口感染致病菌分布及危险因素。方法回顾性分析在我院重症监护病房住院期间发生PI的189例患者的临床资料,统计患者伤口感染发生情况及其致病菌种类,分析导致患者发生伤口感染的危险因素。结... 详细信息

目的探讨重症监护病房压力性损伤(PI)患者的伤口感染致病菌分布及危险因素。方法回顾性分析在我院重症监护病房住院期间发生PI的189例患者的临床资料,统计患者伤口感染发生情况及其致病菌种类,分析导致患者发生伤口感染的危险因素。结果重症监护病房189例PI患者中,有32例(16.93%)发生了伤口感染。伤口分泌物标本中共分离出病原菌48株,革兰氏阳性菌、革兰氏阴性菌及真菌分别有19株(39.58%)、27株(56.25%)和2株(4.17%)。年龄≥70岁、创面分期3~4期、合并组织水肿、合并糖尿病、血浆白蛋白水平1,P<0.05),而加用中药敷料及有自主翻身能力是避免发生伤口感染的保护性因素(OR<1,P<0.05)。结论重症监护病房PI患者伤口感染中革兰氏阴性菌检出率较高,年龄越大、创面分期3~4期、合并组织水肿、合并糖尿病、血浆白蛋白水平较低、PI持续时间较长、大小便失禁的PI患者越容易出现伤口感染,因此,临床可使用针对性的抗生素,加用中药敷料,协助患者勤翻身等,以减少PI伤口感染。

关键词：重症监护病房压力性损伤伤口感染致病菌影响因素

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Endovascular repair of aortoiliac aneurysm with a hybrid technique to preserve pelvic perfusion

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中华医学杂志(英文版) 2011年第23期124卷 4105-4108页

作者： wu wei-wei JIANG Xue-ying LIU Bao CHEN Yu LIU Chang-wei Department of Vascular Surgery Peking Union Medical College Hospital Chinese Academy of Medical Science Beijing 100032China Department of Anesthesiology Beijing Tongren Hospital Capital Medical University Beijing 100005 China

Endovascular aneurysm repair(EVAR) has been proven to be an effective and safe technique for abdominal or iliac artery ***,for aneurysms extending to both iliac bifurcations,routine EVAR will occlude both internal iliac arteries(IIAs),which may increase the risk for pelvic *** endovascular techniques have been developed to preserve the pelvic perfusion in EVAR for such *** article reports an endovascular repair of an aortoiliac aneurysm with an external iliac artery(EIA) to the IIA endograft to preserve the pelvic ***,an endograft was advanced into the left IIA under the help of an inflated aortic *** were deployed to embolize the distal type-1 endoleak from the tunnel around the *** an aortouniiliac endograft and an iliac extension were deployed below the renal arteries extending to the right ***,a right-to-left femoro-femoral artery bypass was constructed. Angiography at completion and computed tomography after 6 months demonstrated patency of all grafts and complete exclusion of the aneurysm without any *** repair with an ElA-to-IIA endograft to preserve the pelvic inflow is a feasible and effective technique for aortoiliac *** embolization might be an option to repair the distal type of *** balloon assisted U-turn technique may help advance the endovascular device over a sharp-angled vessel bifurcation.

关键词： abdominal aortic aneurysm internal iliac artery endovascular repair hybrid technique pelvic perfusion

对抗环境中基于种群多样性的鲁棒策略生成方法

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计算机工程与科学 2024年第6期46卷 1081-1091页

作者：庄述鑫陈永红郝一行吴巍炜徐学永王万元东南大学计算机科学与工程学院江苏南京211189 沈阳飞机设计研究所扬州协同创新研究院有限公司江苏扬州210016 北方信息控制研究院集团有限公司江苏南京211189

在对抗博弈环境中,目标智能体希望生成具有高鲁棒性的博弈策略,使得目标智能体在面对不同对手策略时,始终具有较高的收益。现有的基于自我博弈的策略生成方法通常会过拟合到针对对手某个特定策略进行学习,所学习到的策略鲁棒性低且容易... 详细信息

在对抗博弈环境中,目标智能体希望生成具有高鲁棒性的博弈策略,使得目标智能体在面对不同对手策略时,始终具有较高的收益。现有的基于自我博弈的策略生成方法通常会过拟合到针对对手某个特定策略进行学习,所学习到的策略鲁棒性低且容易受到其他对手策略的攻击。此外,现有的结合深度强化学习和博弈论方法迭代生成对手策略的方法在复杂且具有庞大决策空间的对抗场景下收敛效率低。鉴于此,提出一种基于种群多样性的鲁棒策略生成方法,其中对抗双方各自维护一个种群策略池,并且需要保证种群中的策略是具有多样性的,以此生成鲁棒的目标策略。为了保证种群多样性,将从策略的行为和质量2个视角度量策略的多样性,其中行为多样性是指不同策略状态-动作轨迹的差异性,质量多样性是指不同策略面对相同对手时最终获得的收益的差异性。最后,在典型的具有连续状态、连续动作的对抗环境中验证了所提出的基于种群多样性所生成的策略的鲁棒性。

关键词：对抗环境深度强化学习种群多样性 Shapley value 行为表征

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HYDRAULIC CHARACTERISTICS OF PARTIAL OPENING OF THE WORKING GATE FOR A DISCHARGE TUNNEL

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Journal of Hydrodynamics 2007年第4期19卷 488-493页

作者： wu Jian-hua FENG Shu-rong wu wei-wei RUAN Shi-ping College of Water Conservancy and Hydropower Engineering Hohai University Nanjing 210098 China China Hydro Mid-South Design and Research Institute Changsha 410014 China

The partial opening of the working gate for a discharge tunnel is used more and more widely in the various conditions, such as releasing discharge to meet the needs of the various stages under construction, or of the operations at low reservoir levels. In this article the hydraulic characteristics were investigated of the partial opening of the working gate based on the physical model experiments of the discharge tunnel for the Longtan Hydropower Project, including the discharge coefficient, the surface profile of the free flow section, the bottom pressure distribution of the tunnel with an aerator, the cavity length just from the ramp, and the wall pressure of the curve section of the outlet. Some new issues were discussed and the properties were presented of the partial opening of the gate.

关键词： partial opening hydraulic characteristics working gate discharge tunnel