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Preventive Effects of Qingfei Yihuo Capsules(清肺抑火胶囊)on Air Pollution Associated Exacerbation of Chronic Obstructive Pulmonary Disease:A Single-blind,Randomized,Controlled Trial

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Chinese Journal of Integrative Medicine 2020年第11期26卷 806-811页

作者： Hu Wei-ping wu Xiao-dan Li Zhuo-zhe Zhang Jing Department of Pulmonary Medicine Zhongshan Hospital of Fudan UniversityShanghai200032China

Objective To investigate the efficacy of Qingfei Yihuo Capsules(清肺抑火胶囊,QYCs)in preventing the air pollution associated exacerbation of chronic obstructive pulmonary disease(COPD).Methods This was a prospective,parallel,single-blind,randomized,placebo-controlled *** patients with stable Group D COPD were randomly allocated to receive either oral QYCs(intervention group)or placebos(control group,30 cases per group)for 15 days in the presumed high-incidence air pollution season and followed-up for 1 *** groups were given individualized Western medicine therapy according to the Global Initiative for Chronic Obstructive Lung Disease criteria as *** and separate numbers of acute exacerbation(AE)associated with striking air pollution was the primary *** outcomes included total numbers of deteriorating respiratory symptoms and separate numbers associated with striking air pollution,as well as scores of COPD Assessment Test(CAT)and modified Medical Research Council Scale(mMRC).Results All the 60 patients completed the *** was no statistical significance in total numbers of AE between the two groups(P>0.05).Compared with the control group,a significant reduction in air-pollution associated numbers of deteriorated respiratory symptoms was observed in the intervention group(1.9–1.2 vs.3.6–2.4,P0.05).Only 2 patients in the intervention group reported diarrhea and recovered after drug *** For patients with Group D COPD,oral QYCs in high-incidence season of air pollution can effectively mitigate respiratory symptoms associated with air pollution,although there was no evidence that it had a significant reductive effect on AEs.(Registered at Chinese Clinical Trial Registry,registration ***-IOR-17013827).

关键词： chronic obstructive pulmonary disease Qingfei Yihuo Capsules air pollution acute exacerbation randomized controlled trial Chinese medicine

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基于数据挖掘的中医药治疗原发性干燥综合征燥湿互结证的用药规律研究

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风湿病与关节炎 2024年第4期13卷 7-11,17页

作者：李媛杜梦梦茹尘李乐晴卢斯仪刘小平朱跃兰侯秀娟北京中医药大学北京100029 北京中医药大学东方医院北京100078

目的:总结北京中医药大学东方医院风湿科研究团队治疗原发性干燥综合征燥湿互结证的用药规律。方法:筛选2018年1月至2022年12月原发性干燥综合征燥湿互结证患者的病历资料,使用Excel软件建立数据库并进行统计,采用Modeler 18.0软件进行... 详细信息

目的:总结北京中医药大学东方医院风湿科研究团队治疗原发性干燥综合征燥湿互结证的用药规律。方法:筛选2018年1月至2022年12月原发性干燥综合征燥湿互结证患者的病历资料,使用Excel软件建立数据库并进行统计,采用Modeler 18.0软件进行关联规则和复杂网络分析,联合Cytoscape软件对结果进行可视化。采用SPSS 20.0软件进行聚类分析。结果:共纳入处方139首,涉及188味中药,使用频次≥25次的中药共34味。筛选出药物关联组合73条,复杂网络分析得到核心中药组合丹参-青蒿-石斛-白芍,共得到8个聚类组合。结论:原发性干燥综合征燥湿互结证临证用药以清化湿热、祛瘀生津为法,根据“湿”“热”“燥”“瘀”的不同程度加减化裁,为干燥综合征的临床用药提供思路及参考。

关键词：原发性干燥综合征数据挖掘用药规律关联分析中医药

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基于Informed-RRT 的苹果采摘机械臂路径规划研究

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林业机械与木工设备 2024年第4期52卷 59-65页

作者：郭自良吴玄博殷程凯陈青王金鹏周宏平南京林业大学机械电子工程学院江苏南京210037 南京林业大学林业资源高校加工利用协同创新中心江苏南京210037

针对非结构化复杂环境下采摘机器人成功率低、规划时间长等问题,提出了一种基于informed-RRT的改进采摘运动规划算法。在改进算法中,采用P概率采样取代随机采样,提高采样的目标性,动态步长生成子节点。改进算法提高了Informed-RRT算法... 详细信息

针对非结构化复杂环境下采摘机器人成功率低、规划时间长等问题,提出了一种基于informed-RRT的改进采摘运动规划算法。在改进算法中,采用P概率采样取代随机采样,提高采样的目标性,动态步长生成子节点。改进算法提高了Informed-RRT算法探索未知空间的速度和灵活性,提高最优路径的收敛速度。二维仿真实验表明,与Informed-RRT相比,改进算法可将初始路径查询更短,成功率更高。通过三维仿真实验可以看出,提出的改进采摘机械臂规划算法,实现了快速的路径查询,提高了规划查询率,降低了索引的盲目性,验证了该算法的有效性与优越性。

关键词：采摘机器人运动规划机械臂改进informed-RRT算法

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Monthly variation in litterfall and the amount of nutrients in an Aleurites montana plantation

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Forestry Studies in China 2012年第1期14卷 30-35页

作者： LIN Han HONG Tao wu Cheng-zhen CHEN Hui CHEN Can LI Jian LIN Yong-ming FAN Hai-lan Fujian Agriculture and Forestry University Fujian Forest Ecological System Process and Management Key Laboratory Fuzhou350002 P. R. China

In this study, the dynamics of monthly variation in litterfall and the amount of nutrients, i.e., organic C, N, P and K, in an Aleurites montana plantation were analyzed, based on a field study and experiments over one year. The results show that the litterfall mass of A. montana collected generally presents an ascending trend with maximum defoliation occurring in the autumn and winter （October-December）, accounting for 75.67% of the total amount of annual litterfalk The sequence in the amount of nutrients in A. montana litter was as follows： organic C 〉 N 〉 K 〉 P; their monthly amounts show various dynamic curves. Similar to the dynamics of the mass of monthly litterfall, the monthly returns of C, N, P and K generally show an ascending trend with their peak values all occurring in December. The mass of A. montana litterfall and the dynamics of its monthly nutrient return provide, to a certain degree, a scientific reference for planting and fertilizing A. montana.

关键词： Aleurites montana litterfall monthly variation nutrient amounts

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有氧八段锦联合踏车运动训练对慢性阻塞性肺疾病合并慢性心力衰竭的干预效果

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心血管康复医学杂志 2024年第4期33卷 395-401页

作者：杨爱萍尹枭孟吴君华郭建英徐维国绵阳市中心医院呼吸与危重症医学科四川绵阳621000

目的:观察有氧八段锦联合踏车运动训练对慢性阻塞性肺疾病(COPD)合并慢性心力衰竭(CHF)的干预效果。方法:纳入2019年1月至2021年6月间绵阳市中心医院收治的COPD合并CHF患者180例,根据随机数字表法均分为对照组(基础治疗及干预)和试验组... 详细信息

目的:观察有氧八段锦联合踏车运动训练对慢性阻塞性肺疾病(COPD)合并慢性心力衰竭(CHF)的干预效果。方法:纳入2019年1月至2021年6月间绵阳市中心医院收治的COPD合并CHF患者180例,根据随机数字表法均分为对照组(基础治疗及干预)和试验组(在对照组基础上给予有氧八段锦联合踏车运动训练),两组均干预12周。比较两组干预前、4周、8周和12周后的慢阻肺评估测试量表(CAT)评分、左心室射血分数(LVEF)、左心室收缩末期容积(LVESV)和左心室舒张末期容积(LVEDV)、改良呼吸困难指数(mMRC)和明尼苏达心力衰竭生活质量问卷(MLHFQ)评分。结果:干预12周期间,两组CAT评分、LVESV、LVEDV、mMRC及MLHFQ评分呈逐渐降低趋势,LVEF呈逐渐升高趋势(P<0.05或<0.01)。与对照组相比,干预12周后试验组CAT评分[(17.47±3.96)分比(13.36±3.42)分]、LVEDV[(139.44±7.12)ml比(131.74±6.47)ml]、LVESV[(81.84±8.54)ml比(74.29±9.18)ml]、mMRC评分[(1.67±0.47)分比(1.42±0.50)分]和MLHFQ各维度分及总分[(40.07±6.86)分比(32.54±6.61)分]均显著降低,LVEF[(41.29±4.76)%比(44.56±4.42)%]显著升高,P均<0.001。结论:在基础治疗上增加有氧八段锦联合踏车运动训练,可显著改善COPD合并CHF患者的心肺功能,缓解呼吸困难并提高生活质量,值得推广。

关键词：心力衰竭肺疾病,慢性阻塞性运动疗法

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Laparoscopic distal pancreatectomy is as safe and feasible as open procedure:A meta-analysis

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World Journal of Gastroenterology 2012年第16期18卷 1959-1967页

作者： Kun Xie Yi-ping Zhu Xiao-wu Xu Ke Chen Jia-Fei Yan Yi-ping Mou Department of General Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina

AIM:To evaluate the feasibility and safety of laparoscopic distal pancreatectomy(LDP) compared with open distal pancreatectomy(ODP).METHODS:Meta-analysis was performed using the databases,including PubMed,the Cochrane Central Register of Controlled Trials,Web of Science and BIOSIS *** should contain quantitative data of the comparison of LDP and *** article was reviewed by two *** of operative time,spleen-preserving rate,time to fluid intake,ratio of malignant tumors,postoperative hospital stay,incidence rate of pancreatic fistula and overall morbidity rate were ***:Nine articles with 1341 patients who underwent pancreatectomy met the inclusion *** was performed in 501(37.4%) patients,while ODP was performed in 840(62.6%) *** were significant differences in the operative time,time to fluid intake,postoperative hospital stay and spleen-preserving rate between LDP and *** was no difference between the two groups in pancreatic fistula rate [random effects model,risk ratio(RR) 0.996(0.663,1.494),P = 0.983,I2 = 28.4%] and overall morbidity rate [random effects model,RR 0.81(0.596,1.101),P = 0.178,I2 = 55.6%].CONCLUSION:LDP has the advantages of shorter hospital stay and operative time,more rapid recovery and higher spleen-preserving rate as compared with ODP.

关键词： Laparoscopy Distal pancreatectomy Pancreatic fistula Spleen-preserving Morbidity

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A hybrid discrete particle swarm optimization-genetic algorithm for multi-task scheduling problem in service oriented manufacturing systems

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Journal of Central South University 2016年第2期23卷 421-429页

作者：武善玉张平李方古锋潘毅 School of Computer Science and Engineering South China University of Technology Department of Computer Science College of Staten Island Department of Computer Science Georgia State University

To cope with the task scheduling problem under multi-task and transportation consideration in large-scale service oriented manufacturing systems(SOMS), a service allocation optimization mathematical model was established, and then a hybrid discrete particle swarm optimization-genetic algorithm(HDPSOGA) was proposed. In SOMS, each resource involved in the whole life cycle of a product, whether it is provided by a piece of software or a hardware device, is encapsulated into a service. So, the transportation during production of a task should be taken into account because the hard-services selected are possibly provided by various providers in different areas. In the service allocation optimization mathematical model, multi-task and transportation were considered simultaneously. In the proposed HDPSOGA algorithm, integer coding method was applied to establish the mapping between the particle location matrix and the service allocation scheme. The position updating process was performed according to the cognition part, the social part, and the previous velocity and position while introducing the crossover and mutation idea of genetic algorithm to fit the discrete space. Finally, related simulation experiments were carried out to compare with other two previous algorithms. The results indicate the effectiveness and efficiency of the proposed hybrid algorithm.

关键词： service-oriented architecture (SOA) cyber physical systems (CPS) multi-task scheduling service allocation multi-objective optimization particle swarm algorithm

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Phenotyping of Salvia miltiorrhiza Roots Reveals Associations between Root Traits and Bioactive Components

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Plant Phenomics 2023年第4期5卷 746-756页

作者： Junfeng Chen Yun Wang Peng Di Yulong wu Shi Qiu Zongyou Lv Yuqi Qiao Yajing Li Jingfu Tan Weixu Chen Ma Yu ping Wei Ying Xiao Wansheng Chen The SATCM Key Laboratory for New Resources&Quality Evaluation of Chinese Medicine Institute of Chinese Materia MedicaShanghai University of Traditional Chinese MedicineShanghai 201203China School of Medicine Shanghai UniversityShanghai 200444China State Local Joint Engineering Research Center of Ginseng Breeding and Application Jilin Agricultural UniversityChangchun 130118China School of Computer Science Sichuan Normal UniversityChengdu 610066China Shangyao Huayu(Linyi)Traditional Chinese Resources Co. Ltd.Linyi 276000China School of Life Science and Engineering Southwest University of Science and TechnologyMianyang 621010SichuanChina Sichuan Academy of Traditional Chinese Medicine Chengdu 610041China Department of Pharmacy Changzheng HospitalSecond Military Medical UniversityShanghai 200003China

Plant phenomics aims to perform high-throughput,rapid,and accurate measurement of plant traits,facilitating the identification of desirable traits and optimal genotypes for crop *** miltiorrhiza(Danshen)roots possess remarkable therapeutic effect on cardiovascular diseases,with huge market *** great advances have been made in metabolic studies of the bioactive metabolites,investigation for *** roots on other physiological aspects is ***,we developed a framework that utilizes image feature extraction software for in-depth phenotyping of *** *** employing multiple software programs,*** roots were described from 3 aspects:agronomic traits,anatomy traits,and root system *** K-means clustering based on the diameter ranges of each root branch,all roots were categorized into 3 groups,with primary root-associated key *** a proof of concept,we examined the phenotypic components in a series of randomly collected *** roots,demonstrating that the total surface of root was the best parameter for the biomass prediction with high linear regression correlation(R^(2)=0.8312),which was sufficient for subsequently estimating the production of bioactive metabolites without content *** study provides an important approach for further grading of medicinal materials and breeding practices.

关键词： Root utilize anatomy

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Oxygen-deficient ammonium vanadate/GO composites with suppressed vanadium dissolution for ultra-stable high-rate aqueous zinc-ion batteries

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Rare Metals 2023年第11期42卷 3729-3740页

作者： Gui-Long Liu Ting Zhang Xiao-Jie Li Ru-ping Cao Jin-Ke Shen Dong-Lei Guo Nai-Teng wu Wei-Wei Yuan Ang Cao Xian-Ming Liu Key Laboratory of Function-Oriented Porous Materials of Henan Province College of Chemistry and Chemical EngineeringLuoyang Normal UniversityLuoyang471934China Department of Physics Technical University of DenmarkKongens Lyngby2800Denmark

The structural engineering of hydrated ammonium vanadate as a cathode for aqueous Zn-ion batteries has attracted significant research interest because of its ability to suppress vanadium dissolution and accelerate the electrochemical ***,a feasible fabrication strategy for oxygen-deficient(NH_(4))_(2)V_(10)O_(25)·xH_(2)O/GO(NVOH@GO)composites was proposed,and the charge storage mechanism was *** results of characterization analysis showed that the introduction of graphene oxide(GO)not only enlarged the layer spacing and improved electrical conductivity,providing spacious channels for Zn^(2+)(de)intercalation and accelerating the ion diffusion dynamics,but also induced more oxygen vacancies,inhibited the dissolution of vanadium,and reduced self-discharging,offering additional and stable active sites for ion *** optimized NVOH@GO electrode delivered extraordinarily stable capacities of 334 mAh·g^(-1)after 2000 cycles at 5 A·g^(-1)and 238 mAh·g^(-1)after 10,000cycles at 20 A·g^(-1).Furthermore,ex-situ X-ray diffraction(XRD),X-ray photoelectron spectroscopy(XPS),and Raman results systematically revealed the electrochemical mechanism,including a phase transition reaction and subsequent Zn^(2+)/H_(2)O co-(de)intercalation *** study provides an effective strategy for expanding the interlayer spacing,inducing defect engineering,and enhancing the structural stability of vanadium-based cathodes for Zn-ion batteries and other multivalent aqueous ion batteries.

关键词： Aqueous Zn-ion batteries Vanadium-based cathode Dissolution restraint Oxygen defects Phase transition

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蒙脱石酸活化与微结构变化关系研究

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现代化工 2005年第1期25卷 36-38,40页

作者：吴平霄华南理工大学环境科学与工程学院广东广州510640

对广东和平蒙脱石及其酸处理产物进行了化学分析、X射线粉末衍射分析、红外吸收光谱分析、电子顺磁共振谱、原子力显微镜及魔角旋转核磁共振等研究。结果表明酸处理浓度对蒙脱石的表面结构有很大影响,当用体积分数为20%的H2SO4处理后,... 详细信息

对广东和平蒙脱石及其酸处理产物进行了化学分析、X射线粉末衍射分析、红外吸收光谱分析、电子顺磁共振谱、原子力显微镜及魔角旋转核磁共振等研究。结果表明酸处理浓度对蒙脱石的表面结构有很大影响,当用体积分数为20%的H2SO4处理后,蒙脱石硅氧四面体中的Q3Si结构发生结构重组,有部分转变为畸变的Q3Si结构和Q4Si结构,而Al的结构状态则没有发生任何变化。

关键词：蒙脱石酸处理结构重组

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