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A 2 Kbits Low Power EEPROM for Passive RFID Tag IC

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Chinese Journal of Electronics 2022年第1期31卷 18-24页

作者： HU Jianguo WANG Deming WU Jing School of Microelectronics Science and Technology Sun Yat-sen University School of Physics and Telecommunication Engineering South China Normal University Development Research Institute of Guangzhou Smart City

This paper presents a low power consumption and low cost electrically erasable programmable read-only memory(EEPROM) for radio frequency identification(RFID) tag chip. A read-write circuit with parallel input and serial output is proposed. Only one sensitive amplifier is used to read the data in memory,which can effectively reduce the power consumption of the read operation. Because the tag may be read or written while moving, the internal voltage may change in a wide range. Therefore, this paper designs a charge pump and its control circuit with wide voltage working range.The proposed EEPROM is integrated into an RFID tag chip and fabricated using a 180 nm complementary metal-oxide semiconductor(CMOS) process. Experimental results show that the circuit can work in the input voltage range of 1 V to 1.8 V, and the minimum current of read operation and write operation is 0.68 μA and 30 μA respectively, which has the characteristic of low power consumption.

关键词： EEPROM RFID Low power Very large scale integration (VLSI)

Data Resource Profile:A Protocol of China National Diabetic Chronic Complications Study

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Biomedical and Environmental Sciences 2022年第7期35卷 633-640页

作者： HOU Xu Hong WANG Li Min CHEN Si Yu LIANG Ye Bei ZHANG Mei HUANG Zheng jing CHEN Hong Li WU Jing Zhu WU Jing JIA Wei Ping Department of Endocrinology and Metabolism Shanghai Jiao Tong University Affiliated Sixth People's HospitalShanghai Diabetes InstituteShanghai Key Laboratory of Diabetes MellitusShanghai Clinical Center for DiabetesShanghai Key Clinical Center for Metabolic DiseaseShanghai 200233China National Center for Chronic and Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China Department of Endocrinology and Metabolism Suzhou Dushu Lake Hospital(Dushu Lake Hospital Affiliated to Soochow University)Suzhou 215000JiangsuChina Department of Endocrinology and Metabolism Shanghai General HospitalShanghai 200080China

Diabetes affects approximately 10.5%of adults worldwide,and its chronic complications lead to severely disabling sequelae and premature death,thus placing a heavy healthcare burden on both patients affected and society[1].China has experienced a dramatic increase in diabetes prevalence from 0.67%in 1980[2]to 12.8%in 2018[3]and has approximately one-quarter of people with diabetes worldwide[1].It is therefore essential to understand the epidemiologic characteristics of the chronic complications and co-morbidities of diabetes,and the current status of diabetes management to guide planning for appropriate diabetes care and intervention for these complications and co-morbidities at the national level[4-7].

关键词： diabetes Chronic death

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政治与道德的近现代认知

思想战线 2009年第4期35卷 79-84页

作者：武经伟云南大学<思想战线>编辑部

把道德范畴从政治的主要内涵中剥离出来,使政治成为一门以人的理性和经验为指导的学问,这是从文艺复兴时期马基雅维利开始的。政治学研究曾经历资产阶级革命、科学主义和理性主义的洗礼,形成了多种范式。但在政治的道德属性问题上似乎... 详细信息

把道德范畴从政治的主要内涵中剥离出来,使政治成为一门以人的理性和经验为指导的学问,这是从文艺复兴时期马基雅维利开始的。政治学研究曾经历资产阶级革命、科学主义和理性主义的洗礼,形成了多种范式。但在政治的道德属性问题上似乎划了一个螺旋式的圆,最终在19世纪末的美国形成了国际学术共同体和相对完备的学科体系,完成了近代政治学向现代科学的转变。马克思主义创始人的政治思想在这种转变中产生了重大而深远的影响。

关键词：政治道德政治理性研究范式学科体系

Influences of Multi-Component Supplementary Cementitious Materials on the Performance of Metakaolin Based Geopolymer

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Journal of Renewable Materials 2022年第7期10卷 1813-1828页

作者： WU Jing Ren Luo Sha Ding Ping Duan School of Civil Engineering and Architecture Wuhan University of TechnologyWuhan430070China wuhan Hanyang Municipal Construction Group Co. Ltd.Wuhan430050China Faculty of Materials Science and Chemistry Key Laboratory of Geological Survey and Evaluation of Ministry of EducationChina University of GeosciencesWuhan430074China Guangxi Key Laboratory of New Energy and Building Energy Saving Guilin University of TechnologyGuilin541004China Zhejiang Institute China University of Geosciences(Wuhan)Hangzhou311305China Key Laboratory of Advanced Building Materials of Anhui Province Anhui Jianzhu UniversityHefei230022China Key Laboratory of Road Structure and Materials of Ministry of Transport Chang’an UniversityXi’an710064China

In this study,the workability and reaction mechanism of metakaolin(MK)based geopolymer blended with rice husk ash(RHA)and silica fume(SF)was investigated.The prepared samples were subjected to tests including compressive strength and fluidity tests.X-ray diffraction(XRD)and Scanning electron microscope(SEM)were employed to explore the phase composition and microstructure of geopolymers.The molecular bonding information of geopolymer was provided by Fourier transform infrared spectroscopy(FTIR).Meanwhile,the porosity of geopolymer was obtained by Mercury intrusion porosimeter(MIP)analysis.The high-activity RHA obtained after calcination at 600℃ was used as a supplementary cementitious material to prepare geopolymer.The properties of preventing morphology cracking and compressive strength are improved.The addition of RHA and SF changes the working performance of MK based geopolymer and provided a theoretical basis for future practical applications.Meanwhile,the high chemical activity of SF and RHA contributes to the healing of microcracks.

关键词： Rice husk ash silica fume metakaolin geopolymer

Qianjin Wenwu decoction suppresses renal interstitial fibrosis by enhancing the degradation of extracellular matrix in mice with unilateral ureteral obstruction

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Chinese Journal of Natural Medicines 2023年第4期21卷 253-262页

作者： JIN Chengshan wu Xiaotian YOU Yue WANG Yuing WU Jing ZUO Along ZHENG Yan GUO Jianpeng Key Laboratory of Natural Medicines of the Changbai Mountain Ministry of EducationCollege of PharmacyYanbian UniversityYanji 133002China Yanbian University Hospital Yanji 133002China Yanbian Medical and Health Industry Pilot Base College of PharmacyYanbian UniversityYanji 133002China Yanbian Chaoyao Biotechnology Co. Ltd.Yanji 133002China

Diabetic kidney disease(DKD)is the most common complication of diabetes mellitus(DM).Qianjin Wenwu decoction(QWD),a well-known traditional Korean medicine,has been used for the treatment of DKD,with satisfactory therapeutic effects.This study was designed to investigate the active components and mechanisms of action of QWD in the treatment of DKD.The results demonstrated that a total of 13 active components in five types were found in QwD,including flavonoids,flavonoid glycosides,phenylpropionic acids,saponins,coumarins,and lignins.Two key proteins,TGF-β1 and TIMP-1,were identified as the target proteins through molecular docking.Furthermore,QWD significantly suppressed Scr and BUN levels which increased after unilateral ureteral obstruction(UUO).Hematoxylin&eosin(H&E)and Masson staining results demonstrated that QWD significantly alleviated renal interstitial fibrosis in UUO mice.We also found that QWD promoted ECM degradation by regulating MMP-9/TIMP-1 homeostasis to improve renal tubulointerstitial fibrosis and interfere with the expression and activity of TGF-βl in DKD treatment.These findings explain the underlying mechanism of QWD for the treatment of DKD,and also provide methodological reference for investigating the mechanism of traditional medicine in the treatment of DKD.

关键词： QianJin Wenwu Decoction(QWD) Diabetic kidney disease(DKD) Pharmacodyamic material basis Molecular docking TGF-β1 Extracellular matrix(ECM)

Leveraging CDC’s Advantages in Enhancing Cancer Prevention and Control

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China CDC weekly 2020年第16期2卷 265-267页

作者： jing wu National Center for Chronic and Non-Communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina.

The 26th National Cancer Week takes place from April 15–21,2020,and we would like to take this opportunity to raise the awareness for all parts of our society.This year’s theme is“Joint Action for Anti-Cancer”(1).The government will continue to assume a leading role,while private organizations and individuals are encouraged to participate proactively.The goal is to involve all citizens in the building and development of a supportive environment for cancer prevention and control with the benefits jointly shared by all.

关键词： Cancer prevention jointly

An Important but Overlooked Measure for Containing the COVID-19 Epidemic: Protecting Patients with Chronic Diseases

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China CDC weekly 2020年第15期2卷 249-250页

作者： jing wu National Center for Chronic and Non-Communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

The COVID-19 outbreak has rapidly spread around the world over the past several weeks.On March 11,2020,the World Health Organization designated it as pandemic(1)and as of 23∶59 CET March 19,2020,there were a total of 234,073 confirmed cases and 9,840 deaths in 176 countries,areas,or territories(2).The COVID-19 global pandemic posts a significant global public health challenge to every individual around the world(3–4).

关键词： has COV fir

Optical substrates for drug-metabolizing enzymes: Recent advances and future perspectives

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Acta Pharmaceutica Sinica B 2022年第3期12卷 1068-1099页

作者： Qiang Jin jing jing wu Yue wu Hongxin Li Moshe Finel Dandan Wang Guangbo Ge Shanghai Frontiers Science Center of TCM Chemical Biology Institute of Interdisciplinary Integrative Medicine ResearchShanghai University of Traditional Chinese MedicineShanghai 201203China Department of Clinical Pharmacology College of PharmacyDalian Medical UniversityDalian 116044China Division of Pharmaceutical Chemistry and Technology Faculty of PharmacyUniversity of HelsinkiHelsinki 00014Finland

Drug-metabolizing enzymes(DMEs),a diverse group of enzymes responsible for the metabolic elimination of drugs and other xenobiotics,have been recognized as the critical determinants to drug safety and efficacy.Deciphering and understanding the key roles of individual DMEs in drug metabolism and toxicity,as well as characterizing the interactions of central DMEs with xenobiotics require reliable,practical and highly specific tools for sensing the activities of these enzymes in biological systems.In the last few decades,the scientists have developed a variety of optical substrates for sensing human DMEs,parts of them have been successfully used for studying target enzyme(s)in tissue preparations and living systems.Herein,molecular design principals and recent advances in the development and applications of optical substrates for human DMEs have been reviewed systematically.Furthermore,the challenges and future perspectives in this field are also highlighted.The presented information offers a group of practical approaches and imaging tools for sensing DMEs activities in complex biological systems,which strongly facilitates high-throughput screening the modulators of target DMEs and studies on drug/herb-drug interactions,as well as promotes the fundamental researches for exploring the relevance of DMEs to human diseases and drug treatment outcomes.

关键词： Optical substrates Drug-metabolizing enzymes(DMEs) Fluorescence-based assay High-throughput screening

A buffer overflow detection and defense method based on RiSC-V instruction set extension

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Cybersecurity 2024年第2期7卷 28-43页

作者： Chang Liu Yan-Jun wu jing-Zheng wu Chen Zhao Intelligent Software Research Center Institute of SoftwareChinese Academy of SciencesBejingChina University of Chinese Academy of Sciences BeijingChina State Key Laboratory of Computer Science Institute of SoftwareChinese Academy of SciencesBeijingChina

Buffer overflow poses a serious threat to the memory security of modern operating systems.It overwrites the con-tents of other memory areas by breaking through the buffer capacity limit,destroys the system execution environ-ment,and provides implementation space for various system attacks such as program control flow hijacking.That makes it a wide range of harms.A variety of security technologies have been proposed to deal with system security problems including buffer overflow.For example,No eXecute(NX for short)is a memory management technology commonly used in Harvard architecture.It can refuse the execution of code which residing in a specific memory,and can effectively suppress the abnormal impact of buffer overflow on control flow.Therefore,in recent years,it has also been used in the field of system security,deriving a series of solutions based on NX technology,such as ExecShield,DEP,StackGuard,etc.However,these security solutions often rely too much on the processor archi-tecture so that the protection coverage is insufficient and the accuracy is limited.Especially in the emerging system architecture field represented by RiSC-V,there is still a lack of effective solutions for buffer overflow vulnerabilities.With the continuous rapid development of the system architecture,it is urgent to develop defense methods that are applicable to different system application environments and oriented to all executable memory spaces to meet the needs of system security development.Therefore,we propose BOP,A new system memory security design method based on RISC-V extended instructions,to build a RISC-V buffer overflow detection and defense system and deal with the buffer overflow threat in RIsC-V.According to this method,NX technology can be combined with program control flow analysis,and Nx bit mechanism can be used to manage the executability of memory space,so as to achieve a more granular detection and defense of buffer overflow attacks that may occur in RISC-V system environment.In addition,The memory management an

关键词： RISc-V Operating system security Buffer overflow Control flow hijacking Nx bit Xibop