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Urine Metabonomic Analysis of Interventions Effect of Soy Isoflavones on Rats Exposed to Di-(2-ethylhexyl) Phthalate

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Biomedical and Environmental Sciences 2020年第2期33卷 77-88页

作者： DONG Xin Wen YAO San Qiao wu hao yu ZHANG yun Bo WANG Cheng NA Xiao Lin wu Wei Dong Department of Environmental and Occupational Health School of Public HealthXinxiang Medical UniversityXinxiang 453003HenanChina Department of Environmental Hygiene Public Health CollegeHarbin Medical UniversityHarbin 150086HeilongjiangChina

Objective Di-(2-ethylhexyl) phthalate(DEHP) is a ubiquitous environmental *** an endocrine disruptor,it seriously threatens human health and ecological environmental *** study examines the impact of intervention with soybean isoflavones(SIF) on DEHP-induced toxicity using a metabonomics *** Rats were randomly divided into control(H),SIF-treated(A,86 mg/kg body weight),DEHP-treated(B,68 mg/kg),and SIF plus DEHP-treated(D) *** were given SIF and DEHP daily through diet and gavage,*** 30 d of treatment,rat urine was tested using UPLC/MS with multivariate *** changes were also evaluated using biochemical *** Metabolomics analyses revealed that p-cresol glucuronide,methyl hippuric acid,N1-methyl-2-pyridone-5-carboxamide,lysophosphatidycholine [18:2(9 Z,12 Z)] {lyso PC [18:2(9 Z,12 Z)]},lyso PC(16:0),xanthosine,undecanedioic acid,and N6-acetyl-l-lysine were present at significantly different levels in control and treatment *** SIF supplementation partially protects rats from DEHP-induced metabolic abnormalities by regulating fatty acid metabolism,antioxidant defense system,amino acid metabolism,and is also involved in the protection of mitochondria.

关键词： Di-(2-ethylhexyl) phthalate Soy isoflavones Metabonomics UPLC-QTOF-MS/MS Urine

Manipulation of Ions in Microscopic Surface-Electrode Ion Traps

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Chinese Physics Letters 2013年第7期30卷 72-75页

作者： WAN Wei CHEN Liang wu hao-yu XIE Yi ZHOU Fei FENG Mang State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and Mathematicsand Wuhan National Laboratory for OptoelectronicsChinese Academy of SciencesWuhan 430071 University of the Chinese Academy of Sciences Beijing 100049

The spatial manipulation of ionic qubits in a fast and precise fashion is one of the foremost issues in scalable quantum information processing with trapped *** report our recent efforts toward precise manipulation of trapped ions,including separation,recombination and reordering of the ions,in our home-made microscopic surface-electrode *** also demonstrate the micromotion compensation for the trapped ions by rf-photon cross-correlation,which ensures the cooling of the ions down to the temperature 23.3 mK.

关键词： precise separation quantum

Demonstration of Cold ^(40)Ca^(+) Ions Confined in a Microscopic Surface-Electrode Ion Trap

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Chinese Physics Letters 2013年第1期30卷 67-70页

作者： CHEN Liang WAN Wei XIE Yi wu hao-yu ZHOU Fei FENG Mang State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and MathematicsChinese Academy of SciencesWuhan 430071 University of Chinese Academy of Sciences Beijing 100049

^(40)Ca^(+) ions are successfully confined,under the cooling of a red-detuned laser,in a home-built microscopic surface-electrode(MSE)*** all electrodes deposited on a low-rf-loss substrate,our 500-μm-scale MSE trap is designed involving three potential wells and manufactured by the standard technique of the printed circuit *** linear and two-dimensional crystals of ^(40)Ca^(+) are observed in the trap after preliminary micromotion compensation is carried *** development of the MSE trap aims at large-scale trapped-ion quantum information processing.

关键词： Electrode Surface manufactured

Background-Free Doppler Cooling of Trapped Ions Using Quadrupole Transition

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Chinese Physics Letters 2013年第3期30卷 47-50页

作者： ZHOU Fei XIE Yi CHEN Liang WAN Wei wu hao-yu FENG Mang State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and MathematicsChinese Academy of SciencesWuhan 430071 University of Chinese Academy of Sciences Beijing 100049

We demonstrate experimentally the Doppler cooling of ^(40)Ca^(+) ions using the S_(1/2)→D_(3/2) electric quadrupole transition,in which the scattering light that is much different from the exciting light makes it possible to collect background-free *** idea excluding 397 nm excitation has the advantage of high-sensitivity detection and only employs lasers in red and infrared wavelengths,which should be practical for trapped-ion quantum information processing.

关键词： scattering Transition Doppler

Long-term Di-(2-ethylhexyl) phthalate Exposure Disturbs the Lipid Metabolism Profiles and Hepatic Enzymes in Male Rats:A UPLC-MS-based Serum Metabolomics Analysis

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Biomedical and Environmental Sciences 2021年第11期34卷 920-925页

作者： DONG Xin Wen wu Wei Dong YAO San Qiao ZHANG yun Bo WANG Cheng wu hao yu NA Xiao Lin Department of Environmental and Occupational Health School of Public HealthXinxiang Medical UniversityXinxiang 453003HenanChina Department of Environmental Hygiene Public Health CollegeHarbin Medical UniversityHarbin 150086HeilongjiangChina

In recent years,many investigations have indicated that environmental endocrine disruptors(EEDs)may accelerate the development of obesity[1].One kind of EEDs,di-(2-ethylhexyl)phthalate(DEHP),is ubiquitous in natural e... 详细信息

关键词： Lipid Metab Serum

基于实时监控的碾压混凝土坝施工仿真（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2018年第5期19卷 367-383页

作者： Qian-wei WANG Deng-hua ZHONG Bin-ping wu Jia yu hao-tian CHANG State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin University

目的:碾压混凝土坝施工过程中施工仿真参数会随着施工现场环境变化而变化。本文探讨实时监控方法获取的施工信息对施工进度仿真的影响,研究碾压混凝土坝施工仿真参数自适应更新方法,提高施工仿真的精度。创新点:1.通过碾压混凝土坝施工... 详细信息

目的:碾压混凝土坝施工过程中施工仿真参数会随着施工现场环境变化而变化。本文探讨实时监控方法获取的施工信息对施工进度仿真的影响,研究碾压混凝土坝施工仿真参数自适应更新方法,提高施工仿真的精度。创新点:1.通过碾压混凝土坝施工信息实时获取技术,分析计算碾压混凝土坝施工仿真参数;2.利用贝叶斯更新技术对施工仿真参数进行更新;3.利用模糊均生函数对坝区短期降雨量进行预测;4.建立基于实时监控的碾压混凝土坝施工仿真模型,对碾压混凝土坝施工过程进行仿真并与实际施工进度对比。方法:1.通过实地采集,获取碾压混凝土坝施工过程中实时施工信息(图2);2.通过理论推导,构建施工仿真参数先验分布均值和方差与后验分布均值和方差之间的关系,得到施工仿真参数更新方案(公式(16)和(17));3.通过理论推导,利用已知坝区降雨量数据预测未来短期内的降雨情况(图5);4.通过仿真模拟,得到施工仿真参数更新后的仿真成果并将其与实际施工进行对比,验证本方法的有效性和准确性。结论:1.施工仿真参数的准确性对碾压混凝土坝施工仿真结果准确性有很大影响;2.可以利用贝叶斯更新技术对施工仿真中的仿真参数进行更新,利用模糊均生函数对坝区短时期内降雨量进行预测;3.运用基于实时监控的碾压混凝土坝施工仿真方法对碾压混凝土坝施工过程进行仿真,仿真结果与实际施工进度之间的偏差明显减少,仿真准确性明显提高。

关键词：碾压混凝土坝施工仿真实时监控贝叶斯更新模糊均生函数

Long-term Safety Observations on Side Effects and Com -plications of Non-surgical Sterilization by Chem ical In-stillation of the Fallopian Tubal

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Journal of Reproduction and Contraception 1999年第1期10卷 18-26页

作者： LIU yun-rong(刘云嵘) wu yu-hao(吴裕浩) CHEN Xue-huang(陈学煌) HUANGZhen-jia(黄真嘉) XU Duo(徐铎) CAIGuang-zong(蔡光宗) NationalResearchInstituteforFamilyPlanning Beijing100081China

The present objective is to observe the side effects and complications of fem ale tubalsterilization by phenol-atabrinepaste (PAP) and phenolm ucilage (PM). 1 705 eligible w om en w ere divided random ly into tw o groups, 871 usinig PAP and 834 w om en using PM. Results: Thefeverratesw ere8.0and 4.4( P< 0.01 ) respec- tively in group PAP and group PM. Infection rates of the appendages w ere 2.3 and 1.2 respectively. The incidence of chem ical peritonitis, w ithin the lim its of pelvic cavity, w ere 1.1and 2.4respectively. Perforation of uterus, pelvic ab- scessand ectopicpregnancy w ere notfound during thisobservation. Slightabdom inal pain after the proceduresw ere 33.6and 30.8respectively. Slightvaginalbleed- ing after the procedure w as 23.2 and 18.0 respectively. Menstruation of the w om en w as not affected by the instillation. This five-year follow -up study neither show ed a positivePap testnor a potentialdeseasecaused by thesterilizing agents. This technique isa safe and efficientm ethod for fem ale sterilization.

关键词： Fem ale tube sterilization by chem icalinstillation Phenol-atabrine paste (PAP) Phenolm ucilage(PM) Multi-center random ized clinicaltrial Side-effectand com plication

Management of bronchial rupture after blunt chest trauma in children

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Chinese Medical Journal 2019年第8期132卷 987-989页

作者： yu-hao wu Shou-Liang Jiang yue-Hang Zhou Xin Ji Yong-Gang Li Chun wu Department of Cardiothoracic Surgery Children's Hospital of Chongqing Medical UniversityMinistry of Education Key Laboratory of Child Development and DisordersInternational Science and Technology Cooperation Base of Child Development and Critical DisordersChongqing Key Laboratory of PediatricsChongqing 400014China West China Woman's and Children's Hospital ChengduSichuan 610000China

To the Editor:Bronchial rupture due to blunt chest injury in children is very rare and can go undiagnosed for over 48 *** surgical repair following definitive diagnosis by three-dimensional computed tomography(3D-CT)and bronchoscopy,complications from anastomotic stricture can arise,particularly in very young *** study aimed to present an algorithm for improved early diagnosis and report learnings from treatment of bronchial rupture after blunt chest trauma in nine children.

关键词： bronchial rupture after blunt chest trauma children three-dimensional computed tomography(3D-CT)

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五门十变配穴法与临床应用

中国针灸 2014年第8期34卷 801-804页

作者：吴育豪胡幼平成都中医药大学针灸推拿学院四川成都610075

笔者根据台湾已故针灸名家周左宇先生传授的五门十变化合和互合两种配穴方法,介绍五门十变配穴法的源流,它将传统易理术数与医学相联系,具有不拘时辰、不拘算式、能结合辨证施治、使用范围确切、有较强针对性的学术思想特点,并以临床应... 详细信息

笔者根据台湾已故针灸名家周左宇先生传授的五门十变化合和互合两种配穴方法,介绍五门十变配穴法的源流,它将传统易理术数与医学相联系,具有不拘时辰、不拘算式、能结合辨证施治、使用范围确切、有较强针对性的学术思想特点,并以临床应用案例佐以印证。互合法多用于四肢痹症,化合法则对内科疾病有明显补强作用,为临床取穴开辟了新的思路。

关键词：五门十变配穴法纳甲法痹症