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Reversal Efficacy of SDZ-PSC833 and Verapamil on Drug-Resistant Human Cervical Carcinoma Cells Line

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wuhan University Journal of Natural Sciences 2007年第2期12卷 379-384页

作者： CHEN Hong CHEN Huizhen wu Xufeng LIU shiquan YANG Qingyi Department of Obstetrics and Gynecology Zhongnan Hospital Wuhan University Wuhan 430071 Hubei China

This article discusses the characteristics of the drugresistant human cervical carcinoma cell line HeLa/MMC and investigates reversal effect of SDZ-PSC833（PSC833） and Verapamil （Ver） upon HeLa/MMC. Relative content of cell DNA detection, H3-TdR incorporation test and drug-resistance have been experimented, meanwhile a tumor transplant model in the nude mice for Hela/MMC has been established. Then the volume of cancer, tumor weight, curve line of growing up in tumor -bearing nude mouse and its morphological variation of carcinoma organism are observed to evaluate the reversal effect of PSC833 and VER. It has been found that：（1） Compared with HeLa cells,subline HeLaJ MMC Cells＇ drug-resistant capability against Mitomycin（MMC） or cisplatin（DDP） is as 5.02 folds or 2 folds as that of the former, respectively. The Hela/MMC cell line has characteristics of multi- drug resistance and stronger multiplication; （2） PSC833 and VER can reverse resistance of HeLa/MMC to Mitomycin in ***833 will be a better candidate for reversing multidrug resistant than verapamil in clinic application.

关键词： cervix neoplasma multidrug resistance mitomycimreversion SDZ-PSC833 verapamil

POSETIZATIONS OF DIGRAPHS

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Acta Mathematica Scientia 1988年第1期8卷 109-111页

作者：巫世权 National University of Defense Technology

The topic, posets and graphs, recently comes about as a new branch of combinatorics. This paper is one on the *** to solve a research problem posed by Trotter in [1]. we constructively prove the following theorem of the necessary and sufficient conditions for a digraph to be a posetable ***. A digraph D is a posetable digraph if and only if D—a contains no directed path between u and v for any arc a=(u, v) of D.

关键词： area POSETIZATIONS OF DIGRAPHS

ENUMERATIONS OF SEMIORDERS

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中国科学院大学学报 1994年第1期 11-23页

作者： shiquan wu(Institute of Applied Mathematics, Academia Sinica P.O. Box 2734, Beijing 100080)

ＥＮＵＭＥＲＡＴＩＯＮＳＯＦＳＥＭＩＯＲＤＥＲＳ￥ＳｈｉｑｕａｎＷｕ（ＩｎｓｔｉｔｕｔｅｏｆＡｐｐｌｉｅｄＭａｔｈｅｍａｔｉｃｓ，ＡｃａｄｅｍｉａＳｉｎｉｃａＰ．Ｏ．Ｂｏｘ２７３４，Ｂｅｉｊｉｎｇ１０００８０）Ａｂｓ... 详细信息

ＥＮＵＭＥＲＡＴＩＯＮＳＯＦＳＥＭＩＯＲＤＥＲＳ￥ＳｈｉｑｕａｎＷｕ（ＩｎｓｔｉｔｕｔｅｏｆＡｐｐｌｉｅｄＭａｔｈｅｍａｔｉｃｓ，ＡｃａｄｅｍｉａＳｉｎｉｃａＰ．Ｏ．Ｂｏｘ２７３４，Ｂｅｉｊｉｎｇ１０００８０）Ａｂｓｔｒａｃｔ：ｉｎｔｈｉｓｐａｐｅｒ...

关键词： ordered partition interval order semiorder

A t-Intersection Theorem of Finite Sequences

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中国科学院大学学报 1993年第4期 341-354页

作者： shiquan wu(Institute of Applied Mathematics, Academia Sinica,P. O. Box 2734, Beijing 100080, P. R. China)

Let n,s,s,…, and sbe positive integers. Assume M(s,s…,s)={(x,x,…,x)|0≤x≤s, xis an integer for each i}. F■M(s,s,…,s) iscalled an I~p-intersecting family if for any a=(a,a,…,a),b=(b,b,…,b)∈F,a∧b=min(a,b)>p for at least t i’*** this paper, maximum I~p-intersecting families in M(s,s,…,s) are obtained.1980 AMS Subject Classification: 05A 05, 06A 10

关键词： t-intersecting family finite sequences I_t~p-intersecting family of finite sequences

A MODIFIED HOMOGENEOUS AND SELF-DUAL LINEAR PROGRAMMING ALGORITHM

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Systems Science and Mathematical Sciences 1995年第3期8卷 270-277页

作者： GUO Tiande(Mathematics Department,Qufu Normal University, Qufu 273165,China)wu shiquan(Institute of Applied Mathematics,Academia Sinia, Beijing 100080, China)

ＡＭＯＤＩＦＩＥＤＨＯＭＯＧＥＮＥＯＵＳＡＮＤＳＥＬＦ－ＤＵＡＬＬＩＮＥＡＲＰＲＯＧＲＡＭＭＩＮＧＡＬＧＯＲＩＴＨＭ￥ＧＵＯＴｉａｎｄｅ（ＭａｔｈｅｍａｔｉｃｓＤｅｐａｒｔｍｅｎｔ，ＱｕｆｕＮｏｒｍａｌＵｎｉｖｅｒｓ... 详细信息

ＡＭＯＤＩＦＩＥＤＨＯＭＯＧＥＮＥＯＵＳＡＮＤＳＥＬＦ－ＤＵＡＬＬＩＮＥＡＲＰＲＯＧＲＡＭＭＩＮＧＡＬＧＯＲＩＴＨＭ￥ＧＵＯＴｉａｎｄｅ（ＭａｔｈｅｍａｔｉｃｓＤｅｐａｒｔｍｅｎｔ，ＱｕｆｕＮｏｒｍａｌＵｎｉｖｅｒｓｉｔｙ，Ｑｕｆｕ２７３１６５，Ｃｈ...

关键词： Linear programming interior point algorithms homogeneity self-dual.

ROW-ACTION METHODS FOR CONVEX QUADRATIC PROGRAMMING

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Systems Science and Mathematical Sciences 1994年第4期7卷 352-361页

作者： GUO Tiande(Mathematics Department of Qufu Normal University, Qufu, Shandong 273165, China)wu shiquan(Institute of Applied Mathematics, Academia Sinica, Beijing 100080, China)

ＲＯＷ－ＡＣＴＩＯＮＭＥＴＨＯＤＳＦＯＲＣＯＮＶＥＸＱＵＡＤＲＡＴＩＣＰＲＯＧＲＡＭＭＩＮＧＧＵＯＴｉａｎｄｅ（ＭａｔｈｅｍａｔｉｃｓＤｅｐａｒｔｍｅｎｔｏｆＱｕｆｕＮｏｒｍａｌＵｎｉｖｅｒｓｉｔｙ，Ｑｕｆｕ，Ｓｈａ... 详细信息

ＲＯＷ－ＡＣＴＩＯＮＭＥＴＨＯＤＳＦＯＲＣＯＮＶＥＸＱＵＡＤＲＡＴＩＣＰＲＯＧＲＡＭＭＩＮＧＧＵＯＴｉａｎｄｅ（ＭａｔｈｅｍａｔｉｃｓＤｅｐａｒｔｍｅｎｔｏｆＱｕｆｕＮｏｒｍａｌＵｎｉｖｅｒｓｉｔｙ，Ｑｕｆｕ，Ｓｈａｎｄｏｎｇ２７３１６５，Ｃｈｉｎａ...

关键词： Convex quadratic programming linear programming least-norm solution SOR algorithm gradient algorithm conjugate direction algorithm

A CUTTING PLANE METHOD FOR LINEARBILEVEL PROGRAMS

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Systems Science and Mathematical Sciences 1998年第2期11卷 125-133页

作者： wu shiquan(Institute of APPlied Mathematics, Academia Sinica, Beijing 100080, China)CHEN Yang(North Telecom, Baseline Street, Ottawa, Canada)Patrice Marcotte(Centre de Recherche sac ies fonSPorts, Universite de Montreal, Quebdc, Canada) 中科院应用数学所北京 North Telecom 加拿大 Universite de Montreal 加拿大

In this papert a cutting planelnethod is presented for solving the linear *** optimality criterion for the linear BLPP is derived from two related linear programsconstructed by using the complementarity conditions for the second level problem. Twotypes of cutting planes are developed in order to deal with different situations and to obtaina maximal efficiency. The method makes use of the special cuts and the implicit vertexenumeration idea to avoid some drawbacks in some existing cuttillg plane methods. Thealgorithm can be proved to be finitely convergent.

关键词： Linear bilevel programming convex polyhedron vertex enumeration cutting plane method global optimisation.

STUDY ON INTEGRATED PRODUCTION MANAGEMENT MODEL OF MRPⅡ, JIT AND TOC

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STUDY ON INTEGRATED PRODUCTION MANAGEMENT MODEL OF MRPⅡ, JI...

2005年中国机械工程学会年会

作者： wu Ming, XIONG shiquan, YI Shuping (Dept. of Industrial Engineering, Chongqing Mechanical Institute, Chongqing University, 400030)

＜正＞On the base of analyzing and comparing pluses and minuses of MRPII, JIT, TOC the three kinds of typical production schedule and control method, this paper synthesizes the advantages of MRPII, JIT, TOC three kinds of typical production schedule and control method, and puts forward an Integrated Production Management Model of MRPII, JIT and TOC.

关键词： MRPII JIT TOC integration production management model

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红外光谱在土壤有机质研究中的应用

光谱学与光谱分析 1998年第1期18卷 52-57页

作者：吴景贵席时权姜岩中科院长春应用化学所吉林农业大学

红外光谱法作为有机物结构研究的一种重要手段，已在土壤有机质研究中得到广泛应用，特别是近年来傅里叶变换红外光谱的引入以及与色谱的联用，更使这方面研究获得较大进展。本文就此进展作一概述。

关键词：红外光谱土壤有机质土壤肥力