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Acta Pharmacologica Sinica 2005年第5期26卷 546-550页

作者： Michael G IRWIN Tak-ming wong Department of Anesthesiology Department of Physiology the University of Hong Kong Hong Kong China

Aim:To examine whether the protective effect of remifentanil preconditioning（RPC）on postischemic hearts is mediated by protein kinase（PKC）activation incomparison with ischemic preconditioning（IPC）.Methods:Male Sprague-Dawleyrats were anesthetized and their chests were *** experiment was per-formed with chelerythrine（CHE,2mg/kg）,GF109203X（0.05 mg/kg）protein kinaseC（PKC）inhibitors administered before RPC(remifentanil 6μ***-1·min-1×3 cycle)orIPC,*** size（IS）,as a percentage of the area at risk（AAR）,wasdetermined by triphenyltetrazolium ***:In groups subjected to IPCand RPC the IS/AAR were significantly reduced（IS/AAR from 52.7%±5.5% to12.9%±3.4%,P0.05 vs CON）or IPC（CHE+IPC 53.7%±4.3%,GF+IPC54.1%±6.2%,P>0.05 vs CON）.The difference was not significant in any of thehemodynamic parameters between control and treatment groups during ischemiaand ***:Remifentanil confers myocardial protection againstischemic injury through a mechanism that is similar to IPC and involves PKCactivation.

关键词： remifentanil myocardial ischemia preconditioning myocardial reperfusion injury protein kinase C chelerythrine GF109203X

China's Economy in 2005: At a New Turning Point and Need to Fix Its Development Problems

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China & World Economy 2006年第2期14卷 1-15页

作者： John wong Professor and Research Director of East Asian Institute Singapore.

China＇s economy in 2005 chalked up another year of 9.9 percent surging growth. In 2005 the government＇s attention was focused on the many negative consequences of China＇s past unbridled economic growth, from rural poverty to environmental degradation and wide income disparities, calling for more ＂sustainable growth＂ or ＂balanced development ＂. The new development paradigm fit nicely into President Hu Jintao＇s concept of ＂scientific development＂ and was embraced by the 11th Five-Year Program （2006- 2010）. The year 2006 might go down in China＇s economic history as an important turning point, as the Hu-Wen leadership will start new development strategies to fix problems previously associated with strong economic growth. Strictly speaking, many of China＇s ＂growth problems ＂ from regional disparities to environmental degradation, are actually quite inevitable - as a part of the development process. But their gravity has often been aggravated by poor governance, blatantly pro-growth policies, and local corruption. Overall, the Chinese leadership has come to realize that its past development patterns are physically unsustainable, and politically and socially unacceptable. It has embraced the need to change. But all development changes will take a long time to yield concrete results.

关键词： sustainable development growth problems pro-growth polices redistribution with growth.

China's Economy in 2006/2007:Managing High Growth for Faster Structural Adjustment

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China & World Economy 2007年第2期15卷 1-15页

作者： John wong East Asian Institute National University of Singapore

China ＇ s economy in 2006 continued to register high growth of l 0. 5 to 10. 7percent with low inflation （CPI at 1.3 percenO, dissipating fears of a hard landing. Since its accession to the WTO, China has become a significant global economic player, and is the favorite destination for many regional and global production networks. China is now a truly economic power （jingji daguo）. China ＇s economic leadership is also increasingly confident of its ability to manage China ＇s domestic economic growth and its growing relations with the outside world. Although China＇s growth is expected to slow down in 2007 to approximately 9.5 percent, the national mood now is one of ＂more balanced＂ growth rather than ＂＇fast growth ＂. Therefore, the building of a ＂harmonious society＂ is to be emphasized in China, while letting economic growth solve the burning social and environmental issues. In 2007, the government will also need to deal with various internal and external imbalances. The renminbi will be under even stronger pressure to revalue, given China ＂s record trade surplus of US$160bn and foreign reserves of US$1tn.

关键词： China's economy growth macroeconomic imbalance structural adjustment

One-Pot Synthesis of Substituted Cyclohexanes from Condensation of Aldehyde and Methylketone

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Chinese Chemical Letters 1998年第4期9卷 329-332页

作者： Yin, YG Cheung, KK wong, WT Jingzhou Teachers Coll Dept Chem Jingzhou 434100 Hubei Peoples R China Univ Hong Kong Dept Chem Hong Kong Hong Kong

Three asymmetrically substituted cyclohexanes were prepared from one-pot reactions of aldehydes and methylketones, and the products were characterized by single crystal structure analysis, NMR spectroscopy and microan... 详细信息

关键词： Michael reaction intermolecular condensation substituted cyclohexane

Torsional Characteristics of Single Walled Carbon Nanotube with Water Interactions by Using Molecular Dynamics Simulation

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Nano-Micro Letters 2014年第3期6卷 268-279页

作者： V.Vijayaraghavan C.H.wong School of Mechanical and Aerospace Engineering Nanyang Technological University

The torsional characteristics of single walled carbon nanotube(SWCNT) with water interactions are studied in this work using molecular dynamics simulation method. The torsional properties of carbon nanotubes(CNTs) in a hydrodynamic environment such as water are critical for its key role in determining the lifetime and stability of CNT based nano-fluidic devices. The effect of chirality, defects and the density of water encapsulation is studied by subjecting the SWCNT to torsion. The findings show that the torsional strength of SWCNT decreases due to interaction of water molecules and presence of defects in the SWCNT. Additionally,for the case of water molecules encapsulated inside SWCNT, the torsional response depends on the density of packing of water molecules. Our findings and conclusions obtained from this paper is expected to further compliment the potential applications of CNTs as promising candidates for applications in nano-biological and nano-fluidic devices.

关键词： Carbon nanotube Water interaction Torsion Water encapsulation Nano-fluid Molecular dynamics

Progresses and problems in nano-tribology

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Chinese Science Bulletin 1998年第5期43卷 369-378页

作者： LawrenceK.Y.Li PatrickL.wong State Key Laboratory of Tribology Tsinghua University Beijing China City University of Hong Kong Kowloon Hong Kong

The recent development in the four areas of nano-tribology is analysed. They are micro- and nano-friction and wear, micro- and nano-tribological engineering. The research methods in nano-tribology and thin film lubrication in which five branches are included: equivalent viscusity and flowing characteristics of micro fluid, the transition between ordered molecular film and disordered one, the essence of matrix influence on thin film lubrication, the lubrication mechanism of high polymer lubricants and the problem of superlubricity. Meanwhile, more than 35 problems are proposed which should be solved in the future.

关键词： micro-nanotribology thin film lubrication nano-tribology measuring technique at nanometer scale.

High resolution aerosol optical thickness retrieval over the Pearl River Delta region with improved aerosol modelling

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Science China Earth Sciences 2009年第10期52卷 1641-1649页

作者： wong ManSing NICHOL Janet LEE Kwon Ho Department of Land Surveying and Geo-Informatics The Hong Kong Polytechnic University Earth System Science Interdisciplinary Center University of Maryland (UMD)

Aerosol retrieval algorithms for the MODerate Resolution Imaging Spectroradiometer (MODIS) have been developed to estimate aerosol and microphysical properties of the atmosphere, which help to address aerosol climatic issues at global scale. However, higher spatial resolution aerosol products for urban areas have not been well researched mainly due to the difficulty of differentiating aerosols from bright surfaces in urban areas. Here, a new aerosol retrieval algorithm using the MODIS 500 m resolution images is described, to retrieve aerosol properties over Hong Kong and the Pearl River Delta region. The rationale of our technique is to first estimate the aerosol reflectance by decomposing the top-of-atmosphere reflectance from surface reflectance and Rayleigh path reflectance. For the determination of surface reflectance, a modified Minimum Reflectance Technique (MRT) is used, and MRT images are computed for different seasons. A strong correlation is shown between the surface reflectance of MRT images and MODIS land surface reflectance products (MOD09), with a value of 0.9. For conversion of aerosol reflectance to Aerosol Optical Thickness (AOT), comprehensive Look Up Tables (LUT) are constructed, in which aerosol properties and sun-viewing geometry in the radiative transfer calculations are taken into account. Four aerosol types, namely mixed urban, polluted urban, dust, and heavy pollution, were derived using cluster analysis on three years of AERONET measurements in Hong Kong. Their aerosol properties were input for LUT calculation. The resulting 500 m AOT images are highly correlated (r = 0.89) with AERONET sunphotometer observations in Hong Kong. This study demonstrates the applicability of aerosol retrieval at fine resolution scale in urban areas, which can assist the study of aerosol loading distribution and the impact of localized and transient pollution on urban air quality. In addition, the MODIS 500 m AOT images can be used to study cross-boundary aeroso

关键词： aerosol retrieval aerosol optical thickness AERONET MODIS satellite image

MERACLE:Constructive Layer-Wise Conversion of a Tensor Train into a MERA

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Communications on Applied Mathematics and Computation 2021年第2期3卷 257-279页

作者： Kim Batselier Andrzej Cichocki Ngai wong Delft Center for Systems and Control Delft University of TechnologyDelftthe Netherlands Skolkovo Institute of Science and Technology(SKOLTECH) 121205 MoscowRussia The Department of Electrical and Electronic Engineering The University of Hong KongHong KongChina

In this article,two new algorithms are presented that convert a given data tensor train into either a Tucker decomposition with orthogonal matrix factors or a multi-scale entanglement renormalization ansatz(MERA).The Tucker core tensor is never explicitly computed but stored as a tensor train instead,resulting in both computationally and storage efficient *** the multilinear Tucker-ranks as well as the MERA-ranks are automatically determined by the algorithm for a given upper bound on the relative approximation *** addition,an iterative algorithm with low computational complexity based on solving an orthogonal Procrustes problem is proposed for the first time to retrieve optimal rank-lowering disentangler tensors,which are a crucial component in the construction of a low-rank *** experiments demonstrate the effectiveness of the proposed algorithms together with the potential storage benefit of a low-rank MERA over a tensor train.

关键词： Tensors Tensor train Tucker decomposition HOSVD MERA Disentangler

OrthoGNC:A Software for Accurate Identi?cation of Orthologs Based on Gene Neighborhood Conservation

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Genomics, Proteomics & Bioinformatics 2017年第6期15卷 361-370页

作者： Soheil Jahangiri-Tazehkand Limsoon wong Changiz Eslahchi Department of Computer Science Shahid Beheshti UniversityTehran ***Iran School of Computing National University of SingaporeSingapore 117417Singapore

Orthology relations can be used to transfer annotations from one gene （or protein） to another. Hence, detecting orthology relations has become an important task in the post-genomic era. Various genomic events, such as duplication and horizontal gene transfer, can cause erroneous assignment of orthology relations. In closely-related species, gene neighborhood information can be used to resolve many ambiguities in orthology inference. Here we present OrthoGNC, a software for accurately predicting pairwise orthology relations based on gene neighborhood conservation. Analyses on simulated and real data reveal the high accuracy of OrthoGNC. In addition to orthol- ogy detection, OrthoGNC can be employed to investigate the conservation of genomic context among potential orthologs detected by other methods. OrthoGNC is freely available online at http：//***/softwares/orthognc and http：//***/orthoGNC.

关键词： Orthotogy Homology Gene neighborhood conser-vation Genomic context Comparative genomics

Supramolecular Metal Complex with Ferrocene-conjugated Macrocyclic Triaza Crown Ether as Ligand and Its Electrochemical Property

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Chinese Chemical Letters 1998年第3期9卷 269-272页

作者： Yin, YG Cheung, KK wong, WT Jingzhou Teachers Coll Dept Chem Jingsha 434100 Hubei Peoples R China Univ Hong Kong Dept Chem Hong Kong Peoples R China

A tetranuclear complex [Co(III)(2)(L)(2)(AcO)(2)(OH)](AcO)(2I). 4H(2)O (L = N-ferrocenylmethyl-1,4,7-triaza-cyclononane) was prepared from ligand L . HI and its crystal structure was determined. The crystal exists in P2(1)(/)a space group and its cell parameters are a = 14.285(3)Angstrom, b = 19.888(3)Angstrom, c = 19.133(3)Angstrom; beta = 109.12(2)degrees; V = 5135.8 Angstrom(3); Z = 4. Electrochemical investigation reveals that the oxidation potential of ferrocenyl group in 1 has a 0.11V-positive-shift from that of the ferrocenyl group in ***.

关键词： supermolecule ferrocene host-guest electronic interaction