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Experimental study on boundary lubricity of superficial area of articular cartilage and synovial fluid

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Friction 2024年第5期12卷 981-996页

作者： wenxiao LI Takehiro MORITA Yoshinori SAWAE Departure of Mechanical Engineering Kyushu UniversityFukuoka8190395Japan International Institute for Carton-Neutral Energy Research Kyushu UniversityFukuoka8190395Japan Advanced Research Center for Biomechanics Kyushu UniversityFukuoka8190395Japan

The boundary lubrication mechanism at the articulating surface of natural synovial joints has been the subject of much discussion in *** this study,to elucidate the lubricating function of the superficial area of articular cartilage and synovial fluid(SF),cartilage specimens were processed with four different treatments:gentle and severe washing with detergent,incubation in NaCl solution,and trypsin digestion to selectively remove certain constituents from the cartilage ***,the frictional characteristics were examined in phosphate-buffered saline(PBS)and SF against *** reciprocating sliding tests with a spherical glass probe and square articular cartilage specimens were performed at low contact loads in the mN range to extract the frictional behavior in the superficial area of the cartilage ***,the cartilage surface was observed to confirm the effects of treatments on the morphology of the cartilage surface using a fluorescence microscope and water-immersion *** coefficient of friction(COF)of the prepared cartilage specimens was varied from 0.05 to over 0.3 in ***,a certain group of cartilage specimens exhibited a low COF of less than 0.1 with limited *** the low COF group of specimens,all four treatments increased the COF in PBS to different extents,and fluorescence microscopy revealed that the integrity of the cartilage surface was deteriorated by *** means that the intact cartilage surface had lubricating constituents to maintain low friction,and the removal of such constituents resulted in the loss of the intrinsic boundary lubricity of the cartilage *** variation in the COF of the cartilage specimens was suppressed in SF because it had a clear boundary lubrication effect on the cartilage *** lubricating effect of SF could be confirmed even after degenerative treatment.

关键词： articular cartilage synovial fluid the uppermost superficial layer boundary lubrication

New Algebraic Attacks on Grendel with the Strategy of Bypassing SPN Steps

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Chinese Journal of Electronics 2024年第3期33卷 635-644页

作者： wenxiao QIAO Siwei SUN Lei HU State Key Laboratory of Information Security Institute of Information Engineering Chinese Academy of Sciences School of Cyber Security University of Chinese Academy of Sciences School of Cryptology University of Chinese Academy of Sciences State Key Laboratory of Cryptology

The rapid development of modern cryptographic applications such as zero-knowledge,secure multiparty computation,fully homomorphic encryption has motivated the design of new so-called arithmetization-oriented symmetric *** designing ciphers in this domain is relatively new and not well-understood,the security of these new ciphers remains to be completely *** this paper,we revisit the security analysis of arithmetizat ionoriented cipher *** uses the Legendre symbol as a component,which is tailored specifically for the use in zero-knowledge and efficiently-varifiable proof *** FSE 2022,the first preimage attack on some original full GrendelHash instances was *** a countermeasure,the designer adds this attack into the security analysis and updates the formula to derive the secure number of *** our work,we present new algebraic attacks on *** the preimage attack,we can reduce the complexity or attack one more round than previous attacks for some *** addition,we present the first collision attack on some round-reduced instances by solving the constrained input/constrained output problem for the underlying permutations.

关键词： Ciphers Symbols Multi-party computation Complexity theory Homomorphic encryption

Adaptive observer-based integral event-triggered antivibration control of a full aircraft active landing gear system with irregular runway excitations

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Science China(Information Sciences) 2024年第6期67卷 248-261页

作者： wenxiao HU Chenglong DU Fanbiao LI Xinmin CHEN Chunhua YANG Weihua GUI School of Automation Central South University Research Center in System Engineering for Special Aircrafts Ningbo Institute of Materials Technology and EngineeringChinese Academy of Sciences

This study addresses the antivibration issue of a full aircraft active landing gear system(LGS)under landing impact and runway excitations via a novel adaptive observer-based integral event-triggered control method. First, a full aircraft active LGS comprising a front gear and two synchronized main left and right gears with active suspensions is established, where the information exchange among them is not implemented directly. Second, two adaptive observers are designed separately for the front and main LGSs to identify the varying damping parameters and estimate the system states simultaneously. Third, estimated states are transmitted to a shared network through a novel integral event-triggered mechanism(I-ETM);thus, the front and main LGSs are interconnected, and a networked control scheme for the aircraft LGS is constructed. Additionally, the integrated active control law is designed with the aid of the transmitted states of the front and main LGSs, enhancing the robustness against the pitch vibration of the ***, the L2-stability of the hybrid system is guaranteed to depress the vertical vibration effect of the landing impact and irregular runway excitations, thus improving passenger safety and comfort. Moreover,a codesign method is provided to obtain feasible solutions to the gain matrices of the observers and controllers simultaneously. Simulation and comparison results are presented to illustrate the effectiveness and superiority of the proposed control scheme in antivibration and saving communication resources.

关键词： aircraft active landing gear antivibration control integral event-triggered mechanism adaptive observer \({\cal L}_{2}\)-stability

Up-scaled Teer-UDP850/4 Unbalanced Magnetron Deposition System Used for Mass-Production of CrTiAIN Hard Coatings

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材料热处理学报 2004年第5B期25卷 827-831页

作者： ZHANGGuo-jun YANGShi-cai JIANGBai-ling BAILi-jing CHENDi-chum wenxiao-bin TEERD.G. SchoolofMateriafsScienceandEngineering.Xi＇anUniversityofTechnology Xi＇an.China TeerCoatingsLtd. 290HartleburyTradingEstateHartleburyWorcs.U.K.

Up-scaled deposition process of Teer-UDP850/4 has been established and used for massive production of CrTiAIN hard coatings in applications of anti-wear, cutting and forming tools. This deposition system uses four magnetrons that are arranged by unbalanced magnets to form closed magnetic field enabling the system running in high current density. Elemental metals of Cr, Ti and Al are used as the target materials which are co-deposited with nitrogen forming multialloy nitride, nanoscale multi-layer or superlattice hard coatings. The substrate turntable is desfgned as planet rotation mechanism with three folds so that components or tools with complicate geometry can be uniformly coated onto all their surfaces and cutting edges. The power units for the magnetrons are straight dc whilst the substrate is biased by pulsed dc. Two solid heaters are installed in the system to enable running a wide range of deposition temperature from 200°C to 500°C. The pumping system is powerful that incorporated with a polycold to pump the system to a good vacuum in a very short time. A front door and a movable substrate table are available to benefit easily loading and unloading. Deposition procedure, properties and performance of the coatings is also presented in this paper.

关键词：不平衡磁控管溅射 CrTiAlN 硬质合金涂层热处理

Reconstruct recent multi-population migration history by using identical-by-descent sharing

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Journal of Genetics and Genomics 2024年第6期51卷 642-651页

作者： wenxiao Zhang Kai Yuan Ru Wen Haifang Li Xumin Ni School of Mathematics and Statistics Beijing Jiaotong UniversityBeijing 100044China The Stanley Center for Psychiatric Research Broad Institute of MIT and HarvardCambridgeMA 02142USA Baidu Incorporated Beijing 100085China

Identical-by-descent(IBD)is a fundamental genomic characteristic in population genetics and has been widely used for population history ***,limited by the nature of IBD,which could only capture the relationship between two individuals/haplotypes,existing IBD-based history inference is constrained to two *** this study,we propose a framework by leveraging IBD sharing in multipopulation and develop a method,MatrixiBD,to reconstruct recent multi-population migration ***,we employ the structured coalescent theory to precisely model the genealogical process and then estimate the IBD sharing across multiple *** our model,we establish a theoretical connection between migration history and IBD *** method is rigorously evaluated through simulations,revealing its remarkable accuracy and ***,we apply MatrixiBD to Central and South Asia in the Human Genome Diversity Project and successfully reconstruct the recent migration history of three closely related populations in South *** taking into account the IBD sharing across multiple populations simultaneously,MatrixlBD enables us to attain clearer and more comprehensive insights into the history of regions characterized by complex migration dynamics,providing a holistic perspective on intricate patterns embedded within the recent population migration history.

关键词： Population genetics IBD sharing Migration history Structured coalescent theory Gene flow

GmDFB1,an ARM-repeat superfamily protein,regulates floral organ identity through repressing siRNA-and miRNA-mediated gene silencing in soybean

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Journal of Integrative Plant Biology 2024年第8期66卷 1620-1638页

作者： Jie Li wenxiao Zhang Qing Lu Jiaqi Sun Chuang Cheng Shiyu Huang Shuo Li Qiang Li Wei Zhang Chuanen Zhou bin Liu Fengning Xiang The Key Laboratory of Plant Development and Environmental Adaptation Biology Ministry of EducationSchool of Life SciencesShandong UniversityQingdao 266237China State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China

The development of flowers in soybean(Glycine max)is essential for determining the yield potential of the *** silencing pathways are involved in modulating flower development,but their full elucidation is still ***,we conducted a forward genetic screen and identified an abnormal flower mutant,deformed floral bud1-1(Gmdfb1-1),in *** mapped and identified the causal gene,which encodes a member of the armadillo(ARM)-repeat *** small RNA sequencing(sRNA-seq),we found an abnormal accumulation of small interfering RNAs(si RNAs)and microRNA(miRNAs)in the Gmdfb1 *** further demonstrated that GmDFB1 interacts with the RNA exosome cofactor SUPER KILLER7(Gm SKI7).Additionally,GmDFB1 interacts with the PIWI domain of ARGONAUTE 1(GmAGO1)to inhibit the cleavage efficiency on the target genes of s *** enhanced gene silencing mediated by siRNA and miRNA in the Gmdfb1 mutants leads to the downregulation of their target genes associated with flower *** study revealed the crucial role of GmDFB1 in regulating floral organ identity in soybean probably by participating in two distinct gene silencing pathways.

关键词： ARM-repeat superfamily protein ARGONAUTE 1 SUPER KILLER 7 flower development gene silencing small RNAs soybean

Special issue on system identiﬁcation and estimation

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Control Theory and Technology 2024年第2期22卷 147-148页

作者： Weixing Zheng Tianshi Chen Chengpu Yu wenxiao Zhao Western Sydney University SydneyAustralia The Chinese University of Hong Kong ShenzhenChina Beijing Institute of Technology BeijingChina The Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijingChina

It is our great pleasure and honor to organize this special issue“System Identiﬁcation and Estimation”.System identiﬁcation has been a surprisingly lively and resilient area of research in the control community for many *** grew out of statisticians’interest in time series analysis beginning in the 1940s and became a“regular control topic”in the 1960s,as indicated by theﬁrst IFAC Symposium on System Identiﬁcation held in Prague,Czech Republic,in *** years later,it is still an important area of research in theﬁeld of *** is relevant to ask why the interest in system identiﬁcation has remained so *** answer might be that more and more applications in engineering require mathematical models and the combined use of system identiﬁcation and physical modeling is the basic way to obtain reliable *** special issue is focusing on the latest development,trends,and novel methods for system identiﬁcation and estimation and these contributions will give interesting and inspiring insights into the current status of the area.

关键词： estimation system IFAC

First-principles study on the heterogeneous formation of environmentally persistent free radicals(EPFRs)overα-Fe2O3(0001)surface:Effect of oxygen vacancy

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Journal of Environmental Sciences 2024年第8期142卷 279-289页

作者： wenxiao Pan Shuming He Qiao Xue Xian Liu Jianjie Fu Kang Xiao Aiqian Zhang State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China School of Environment Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310012China College of Resources and Environment University of Chinese Academy of SciencesBeijing 100049China Beijing Yanshan Earth Critical Zone National Research Station University of Chinese Academy of SciencesBeijing 101408China

Metal oxides with oxygen vacancies have a significant impact on catalytic activity for the transformation of organic pollutants in waste-to-energy(WtE)incineration *** study aims to investigate the influence of hematite surface oxygen point defects on the formation of environmentally persistent free radicals(EPFRs)from phenolic compounds based on the first-principles *** oxygen-deficient conditions were considered:oxygen vacancies at the top surface and on the *** simulations indicate that the adsorption strength of phenol on theα-Fe_(2)O_(3)(0001)surface is enhanced by the presence of oxygen ***,the presence of oxygen vacancies has a negative impact on the dissociation of the phenol molecule,particularly for the surface with a defective point at the top ***-kinetic parameters were established over a temperature range of300-1000 K,and lower reaction rate constants were observed for the scission of phenolic O-H bonds over the oxygen-deficient surfaces compared to the pristine *** negative effects caused by the oxygen-deficient conditions could be attributed to the local reduction of FeⅢto FeⅡ,which lower the oxidizing ability of surface reaction *** findings of this study provide us a promising approach to regulate the formation of EPFRs.

关键词： EPFR formation Phenol dissociation Oxygen-vacancy impact Hematite surface First-principles calculation

Inhibitory effect of procyanidin B2 and tannin acid on cholesterol esterase and their synergistic effect with orlistat

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Food Science and Human Wellness 2024年第1期13卷 360-369页

作者： Xiangxin Li Yijing Pu Haitao Jiang wenxiao Jiao Wenjun Peng Wenli Tian Weibo Jiang Xiaoming Fang Institute of Apicultural Research Chinese Academy of Agricultural SciencesBeijing 100093China College of Food Science and Nutritional Engineering China Agricultural UniversityBeijing 100083China College of Food Science and Engineering Qilu University of Technology(Shandong Academy of Sciences)Jinan 250353China

This study was aimed to analyze the effect of procyanidin B2(PC)and tannin acid(TA)on the activities of cholesterol esterase(CEase)and the inhibitory mechanisms of enzymatic *** interaction mechanisms were investigated by enzymatic kinetics,multi-spectroscopy methods,thermodynamics analysis,molecular docking,and dynamic *** and TA could bind with CEase and inhibit the activity of enzyme in a mixed-competitive manner and non-competitive manner,which was verified by molecular docking simulations and dynamics ***,PC and TA showed the synergistic inhibition with ***,UVvis and the thermodynamic analysis revealed that the complexes were formed from CEase and inhibitors by noncovalent *** revealed by the circular dichroism results,both PC and TA decreased enzymatic activities by altering the conformations of *** inhibition of PC and TA on CEase might be one mechanism for its cholesterol-lowering effect.

关键词： Cholesterol esterase Polyphenols Interaction mechanisms Molecular dynamic simulation Synergistic effect