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Microstructure,Mechanical Properties and In Vitro Degradation Behavior of a Novel Biodegradable Mg-1.5Zn-0.6Zr-0.2Sc Alloy

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Journal of Materials Science & Technology 2015年第7期31卷 744-750页

作者： Tao Li Hailong Zhang Yong He ning wen Xitao Wang State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing Institute of Stomatology General Hospital of Chinese People's Liberation Army

A novel Mg-1.5Zn-0.6Zr-0.2Sc （denoted as ZK21-0.2Sc） alloy was developed as potential biodegrad- able implant materials. The microstructure, mechanical properties, and in vitro degradation behavior of the as-cast ZK21-0.2Sc alloy were investigated and compared with ZK21 alloy and pure Mg. The ZK21 -0.2Sc alloy showed a single-phase structure with fine equiaxed grains. The alloy exhibited a good balance between strength and ductility. Both immersion tests and electrochemical tests showed that the ZK21-0.2Sc alloy had the lowest degradation rate in Hank＇s solution. The excellent degradation behavior of ZK21-0.2Sc alloy could be explained by the single-phase and fine grain structure, the more effective protection corrosion film, and the beneficial alloying effects of Zn, Zr and Sc.

关键词： Magnesium alloysScandiumBiomaterialsBiodegradableCorrosion

Electrospinning Preparation ofβ-Cyclodextrin/Glutaraldehyde Crosslinked PVP Nanofibrous Membranes to Adsorb Dye in Aqueous Solution

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Chemical Research in Chinese Universities 2014年第6期30卷 1057-1062页

作者： XIAO ning wen Qian LIU Qingwen YANG Qingbiao LI Yaoxian Colledge of Chemistry Jilin University Changchun 130021 P. R. China

The insoluble β-cyclodextrin/glutaraldehyde crosslinked polyvinylpyrrolidone nanofibrous membranes were prepared by electrospinning technique. The membranes were extensively characterized by various techniques including attenuated total reflectance Fourier transform infrared spectroscopy（ATR-FTIR）, X-ray diffraction（XRD）, scanning electron microscopy（SEM） and UV-visible absorption to correlate membrane characteristics with their performance. The adsorption ability of the nanofibrous membranes was tested by performing extraction of Methyl orange（MO） dye in water. It was observed that β-cyclodextrin incorporated in polyvinylpyrrolidone provided the characteristics of high adsorption capacity of polyvinylpyrrolidone. Results of sorption experiments show that the nanofibrous membranes exhibited an adsorption rate of more than 95% for MO and the MO absorbent was 39.82 mg to per gram of fl-cyclodextrin glutaraldehyde（β-CDXFM） crosslinked PVP under the optimized experimental conditions.

关键词： β-Cyclodextrin Glutaraldehyde Polyvinylpyrrolidone Adsorption Nanofibrous membrane

Laminin-coated multifilament entubulation, combined with Schwann cells and glial cell line-derived neurotrophic factor, promotes unidirectional axonal regeneration in a rat model of thoracic spinal cord hemisection

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Neural Regeneration Research 2021年第1期16卷 186-191页

作者： Ling-Xiao Deng Nai-Kui Liu Ryan ning wen Shuang-Ni Yang Xuejun wen Xiao-Ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteIndiana University School of MedicineIndianapolisINUSA Department of Neurological Surgery Indiana University School of MedicineIndianapolisINUSA Maggie L.Walker Governor’s School RichmondVAUSA Institute for Engineering and Medicine Department of Chemical and Life Science EngineeringVirginia Commonwealth UniversityRichmondVAUSA

Biomaterial bridging provides physical substrates to guide axonal growth across the *** achieve efficient directional guidance,combinatory strategies using permissive matrix,cells and trophic factors are *** the present study,we evaluated permissive effect of poly(acrylonitrile-co-vinyl chloride)guidance channels filled by different densities of laminin-precoated unidirectional polypropylene filaments combined with Schwann cells,and glial cell line-derived neurotrophic factor for axonal regeneration through a T10 hemisected spinal cord gap in adult *** found that channels with filaments significantly reduced the lesion cavity,astrocytic gliosis,and inflammatory responses at the graft-host *** laminin coated low density filament provided the most favorable directional guidance for axonal regeneration which was enhanced by co-grafting of Schwann cells and glial cell line-derived neurotrophic *** results demonstrate that the combinatorial strategy of filament-filled guiding scaffold,adhesive molecular laminin,Schwann cells,and glial cell line-derived neurotrophic factor,provides optimal topographical cues in stimulating directional axonal regeneration following spinal cord *** study was approved by Indiana University Institutional Animal Care and Use Committees(IACUC#:11011)on October 29,2015.

关键词： axonal regeneration extracellular molecule filament density hemisection laminin neurotrophic factor Schwann cell spinal cord injury thoracic transplantation

Leaching of lead from zinc leach residue in acidic calcium chloride aqueous solution

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International Journal of Minerals,Metallurgy and Materials 2015年第5期22卷 460-466页

作者： Le Wang wen-ning Mu Hong-tao Shen Shao-ming Liu Yu-chun Zhai School of Materials and Metallurgy Northeastern University School of Resources and Materials Northeastern University at Qinghuangdao

A process with potentially reduced environmental impacts and occupational hazards of lead-bearing zinc plant residue was studied to achieve a higher recovery of lead via a cost-effective and environmentally friendly process. This paper describes an optimization study on the leaching of lead from zinc leach residue using acidic calcium chloride aqueous solution. Six main process conditions, i.e., the solution pH value, stirring rate, concentration of CaC12 aqueous solution, liquid-to-solid （L/S） ratio, leaching temperature, and leaching time, were inves- tigated. The microstructure and components of the residue and tailing were characterized using scanning electron microscopy （SEM） and X-ray diffraction （XRD）. On the basis of experimental results, the optimum reaction conditions were determined to be a solution pH value of 1, a stirring rate of 500 r·min-1, a CaC12 aqueous solution concentration of 400 g·L-1, a liquid-to-solid mass ratio of 7：1, a leaching tempera- ture of 80℃, and a leaching time of 45 min. The leaching rate of lead under these conditions reached 93.79%, with an iron dissolution rate of 19.28%. Silica did not take part in the chemical reaction during the leaching process and was accumulated in the residue.

关键词： lead metallurgy hydrometaUurgy leach residue zinc calcium chloride leaching rate

New Zircon U-Pb Ages for the Volcano-sedimentary Strata in Yamu,Tibet and their Geological Significance

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Acta Geologica Sinica(English Edition) 2021年第2期95卷 687-690页

作者： XU Peiyan YANG Zhusen ZHENG Yuanchuan HOU Zengqian wen ning YU Chao State Key Laboratory of Geological Processes and Mineral Resources School of Earth Science and ResourcesChinaUniversity of GeosciencesBeijing 100083China Institute of Mineral Resources Chinese Academy of Geological SciencesBeijing 100037China Institute of Geology Chinese Academy of Geological SciencesBeijing 100037China

Objective The Gangdese porphyry Cu deposits(PCDs)are currently the most academically and economically significant in the Lhasa *** for the giant Xiongcun PCD,which were formed in the Jurassic,almost all the others were formed in the Miocene(***,Jiama).Previous studies have shown that these Miocene PCDs have a close spatial and genetic relationship with Jurassic magmatic arcs(Hou et al.,2015).

关键词： Jurassic sedimentary magmatic

A New Hybrid Model of Amino Acid Substitution for Protein Functional Classification

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Chinese Chemical Letters 2005年第8期16卷 1133-1136页

作者： Ke Long WANG Zhi ning wen Fu Sheng NIE Meng Long LI College of Chemistry Sichuan University Chengdu 610064 State Key Laboratory of Chemo/Biosensing and Chemometrics Hunan University Changsha 410082

In this paper, a new hybrid model of amino acid substitution is developed and compared with the others in previous works. The results show that the new hybrid model can characterize the protein sequences very well by ... 详细信息

关键词： Hybrid model of amino acid substitution protein functional classification Fisher weights.

A Semi-relativistic Distorted Wave Calculation of Electron Impact Excitation of Gold

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Chinese Physics Letters 1999年第9期16卷 643-645页

作者： GAO Jun-fang PANG wen-ning GAO Hong SHANG Ren-cheng Laboratory of Polarization Physics Department of Applied PhysicsTsinghua UniversityBeijing 100084

A semi-relativistic distorted wave method has been developed to calculate the differential cross section(DCS)and Stokes parameters for electron impacting excitation of gold atom at 30 *** large angle(≥60°)our DCS results are within the experimental error *** small angle(≤60°)our DCS results deviate a little from the experimental *** the whole range our DCS data are roughly the same as those of complete relativistic distorted wave(RDW)*** P1 and P2 calculated from our semi-relativistic method both in structure and tendency are similar to those of the complete RDW *** particularly,-P3 calculated from two kinds of relativistic methods are almost the same in magnitude and *** difference between our results and those of complete RDW method may come from the neglecting direct relativistic of incident electron in our *** comparing the results with those of experiment and complete RDW method it is deduced that the semi-relativistic distorted wave is a convenient and reliable method.

关键词： calculation. method. structure.

PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons

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Neural Regeneration Research 2023年第2期18卷 357-363页

作者： Wei-Tao Yan wen-Juan Zhao Xi-Min Hu Xiao-Xia Ban wen-Ya ning Hao Wan Qi Zhang Kun Xiong Department of Human Anatomy and Neurobiology School of Basic Medical ScienceCentral South UniversityChangshaHunan ProvinceChina Department of Dermatology Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Department of Human Resources Third Xiangya Hospital of Central South UniversityChangshaHunan ProvinceChina Hunan Key Laboratory of Ophthalmology ChangshaHunan ProvinceChina Key Laboratory of Emergency and Trauma Ministry of EducationCollege of Emergency and TraumaHainan Medical UniversityHaikouHainan ProvinceChina

PANoptosis is a newly identified type of regulated cell death that consists of pyroptosis,apoptosis,and nec roptosis,which simultaneously occur during the pathophysiological process of infectious and inflammatory *** our previous lite rature mining study suggested that PANoptosis might occur in neuronal ischemia/repe rfusion injury,little experimental research has been reported on the existence of *** this study,we used in vivo and in vitro retinal neuronal models of ischemia/repe rfusion injury to investigate whether PAN optosis-like cell death(simultaneous occurrence of pyroptosis,apo ptosis,and necroptosis)exists in retinal neuronal ischemia/repe rfusion *** results showed that ischemia/repe rfusion injury induced changes in morphological features and protein levels that indicate PANoptosis-like cell death in retinal neurons both in vitro and in ***/repe rfusion inju ry also significantly upregulated caspase-1,caspase-8,and NLRP3 expression,which are important components of the *** results indicate the existence of PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons and provide preliminary experimental evidence for future study of this new type of regulated cell death.

关键词： apoptosis gasdermin-D(GSDMD) ischemia/reperfusion mixed lineage kinase domain-like protein(MLKL) necroptosis NOD-like receptor protein 3(NLRP3) PANoptosis pyroptosis receptor-interacting protein kinase 3(RIPK3) retinal neuron

Experimental observation of spontaneous symmetry breaking in a quantum phase transition

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Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 34-39页

作者： wen ning Ri-Hua Zheng Jia-Hao Lu Fan Wu Zhen-Biao Yang Shi-Biao Zheng Fujian Key Laboratory of Quantum Information and Quantum Optics College of Physics and Information EngineeringFuzhou UniversityFuzhou 350108China Hefei National Laboratory Hefei 230088China

Spontaneous symmetry breaking(SSB)plays a central role in understanding a large variety of phenomena associated with phase transitions,such as superfluid and *** far,the transition from a symmetric vacuum to a macroscopically ordered phase has been substantially *** process bridging these two distinct phases is critical to understanding how a classical world emerges from a quantum phase transition,but so far remains unexplored in *** here report an experimental demonstration of such a process with a quantum Rabi model engineered with a superconducting *** move the system from the normal phase to the superradiant phase featuring two symmetry-breaking field components,one of which is observed to emerge as the classical *** results demonstrate that the environment-induced decoherence plays a critical role in the SSB.

关键词： quantum phase transition Rabi model spontaneous symmetry breaking superconducting circuit Schrodinger cat states

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