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Anatomic characteristics of the lacrimal sac and adjacent bony structures–a computed tomographicdacryocystography research

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International Journal of Ophthalmology(English edition) 2025年第2期18卷 251-257页

作者： Xin-Han Cui yan-wen Fang Li-Min Zhang Ji-Ni Qiu Chao-Ran Zhang yan Wang Eye Institute and Department of Ophthalmology Eye and ENT Hospital of Fudan UniversityShanghai 200031China NHC Key laboratory of Myopia and Related Eye Diseases Key Laboratory of Myopia and Related Eye DiseasesChinese Academy of Medical SciencesShanghai 200031China Shanghai Key Laboratory of Visual Impairment and Restoration Shanghai 200031China Department of Ophthalmology Children’s Hospital of KaifengKaifeng 475000Henan ProvinceChina

AIM:To describe the anatomic characteristics of the lacrimal sac and its adjacent bone structures and to provide surgical recommendations for endoscopic dacryocystorhinostomy(EN-DCR).METHODS:This retrospective comparative study involved 118 sides with complete nasolacrimal duct obstruction and 83 unaffected sides from 126 *** tomographic-dacryocystography(CT-DCG)scans were performed before lacrimal surgery,and image reconstruction was used to obtain continuous 0.75-mm axial,coronal,and segmental sections for *** morphology of the lacrimal sac and its relationship with adjacent bony structures were determined for measurement,as well as the obstructed ***:The height of the lacrimal sac was 12.99±2.10 mm in this *** operculum of the middle turbinate(OMT)was located vertically in the lower third of the lacrimal ***,the junction between the maxillary bone and the lacrimal bone(MB-LB)was close to,mostly(60.2%)posterior to,the lacrimal *** uncinate process was more frequently attached to the lacrimal bones(75.1%).The obstructions were generally located around the entrance of the nasolacrimal duct(NLD).However,some were placed higher,with 7.63%blocked not lower than the *** was a negative correlation between the diameter of the lacrimal sac and the level of obstruction(r=-0.35,P<0.01).CONCLUSION:In this study,the OMT and MB-LB can be served as the landmarks in *** uncinectomy should be performed in most *** obstructions were generally located around the entrance of the NLD,but some extreme individual variations strongly implies the importance of CT-DCG scanning before surgery.

关键词： lacrimal sac nasolacrimal duct obstruction endoscopic dacryocystorhinostomy computed tomographic-dacryocystography

Subsection cooling system of hot rolling silicon steel and its industrial application

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Journal of Iron and Steel Research International 2025年第1期32卷 159-170页

作者： Qiu-na Wang Ji-quan Sun Li-po yang Hai-shen Wang Li-jie Dong Jie-ming Li Zhen-yang Zhi yan-wen Bi National Engineering Research Center of Flat Rolling Equipment University of Science and Technology BeijingBeijing100083China Hot Rolling Department of Qian’an Iron and Steel Corporation Shougang Company LimitedTangshan064404HebeiChina National Engineering Research Center for Equipment and Technology of Cold Strip Rolling Yanshan UniversityQinhuangdao066004HebeiChina

An online subsection cooling method for hot rolling silicon steel was designed to achieve local adjustment of transverse roll ***,it was able to meet the requirements of edge drop of the strip by using the features of online thermal ***,after the new subsection spray beam was installed at the exit of mill,the special local cooling rules were analyzed for altering the thermal crown of roll according to rolling process ***,the dynamic impact of subsection cooling on the local thermal crown could just be obtained according to the measured ***,the heat transfer coefficient was determined by different subsection cooling curves under varied rolling ***,the rolling rhythm and variable conditions were important dynamic factors of transient roll temperature in practical rolling ***,real-time calculation and presetting of the thermal crown were carried out to maximize special requirements of load roll gap on local strip *** this new method,the transient temperature and the thermal crown of roll could be quantitatively controlled *** the practical results showed that the predicted temperature was able to match the measured value by more than 95%.Meanwhile,the adjustable range of thermal crown increased by more than 2.5 ***,the qualification rate of strip edge crown has increased from the original 30%to over 70%.

关键词： Subsection cooling Thermal roll crown Multi-parameter coupling Hot rolling Silicon steel

Five-year complete remission of super-giant hepatocellular carcinoma with hepatectomy followed by sorafenib plus camrelizumab:A case report

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World Journal of Gastrointestinal Surgery 2025年第1期17卷 273-281页

作者： Xiao-Qin Zheng Li-Bo Sun wen-Jie Jin Hui Liu wen-yan Song Hui Xu Ju-Shan Wu Xiao-Jun Wang Chun-yan Gou Hui-Guo Ding Integrated Traditional Chinese and Western Medicine Center Beijing Youan HospitalCapital Medical UniversityBeijing 100069China Department of Surgery Beijing Youan HospitalCapital Medical UniversityBeijing 100069China Institute for Research in Biomedicine Universitàdella Svizzera italianaBellinzona 6500TicinoSwitzerland Department of Pathology Beijing Youan HospitalCapital Medical UniversityBeijing 100069China Department of Radiology Beijing Youan HospitalCapital Medical UniversityBeijing 100069China Department of Gastroenterology and Hepatology Beijing Youan HospitalCapital Medical UniversityBeijing 100069China

BACKGROUND Cirrhotic patients with super-giant hepatocellular carcinoma(HCC)and portal vein invasion generally have a poor *** paper presents a patient with super-giant HCC and portal vein invasion,who underwent hepatectomy followed by a combination of sorafenib and camrelizumab,resulting in complete remission(CR)for 5 *** SUMMARY A 40-year-old male with compensated hepatitis B-related cirrhosis was diagnosed with HCC,Barcelona Clinic Liver Cancer stage *** computed tomography imaging revealed a 152 mm×171 mm tumor in the right liver,invading the portal vein and hepatic *** function was *** patient successfully underwent hepatectomy on July 18,***,by December 2019,HCC recurrence with lung metastases and portal vein invasion were *** started treatment with sorafenib(200 mg twice daily)and camrelizumab(200 mg every 3 weeks).By May 12,2020,the patient was confirmed to have *** was adjusted to 200 mg every 12 weeks from June 16,2021,with the last infusion on March 29,*** no further tumor recurrence was observed,he experienced two episodes of gastrointestinal bleeding due to esophagogastric varices,which were managed with endoscopic *** date,the patient has remained in CR for 5 *** The combination of hepatectomy with sorafenib and camrelizumab can achieve durable CR in patients with supergiant HCC and portal vein *** research is necessary to address these challenges and improve patient outcomes.

关键词： Hepatectomy Sorafenib Camrelizumab Super-giant hepatocellular carcinoma Complete remission Case report

Machine learning model-based prediction of postpancreatectomy acute pancreatitis following pancreaticoduodenectomy:A retrospective cohort study

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World Journal of Gastroenterology 2025年第8期31卷 9-23页

作者： Ji-Ming Ma Peng-Fei Wang Liu-Qing yang Jun-Kai Wang Jian-Ping Song Yu-Mei Li yan wen Bing-Jun Tang Xue-Dong Wang Hepatopancreatobiliary Center Beijing Tsinghua Changgung HospitalBeijing 102218China Department of Information Administration Beijing Tsinghua Changgung HospitalBeijing 102218China Department of Radiology Beijing Tsinghua Changgung HospitalBeijing 102218China Organ Transplantation Qilu HospitalCheeloo College of MedicineShandong UniversityJinan 250012Shandong ProvinceChina Department of Otorhinolaryngology Xiangyang No.1 People’s HospitalXiangyang 441000Hubei ProvinceChina

BACKGROUND The International Study Group of Pancreatic Surgery has established the defi-nition and grading system for postpancreatectomy acute pancreatitis(PPAP).There are no established machine learning models for predicting PPAP following pancreaticoduodenectomy(PD).AIM To explore the predictive model of PPAP,and test its predictive efficacy to guide the clinical *** Clinical data from consecutive patients who underwent PD between 2016 and 2024 were retrospectively *** analysis of PPAP risk factors was performed,various machine learning algorithms[logistic regression,random forest,gradient boosting decision tree,extreme gradient boosting,light gradient boosting machine,and category boosting(CatBoost)]were utilized to develop predictive *** feature elimination was employed to select several variables to achieve the optimal machine *** The study included 381 patients,of whom 88(23.09%)developed *** patients exhibited a significantly higher incidence of postoperative pancreatic fistula(55.68%vs 14.68%,P<0.001),grade C postoperative pancreatic fistula(9.09%vs 1.37%,P=0.001).The CatBoost algorithm outperformed other algorithms with a mean area under the receiver operating characteristic curve of 0.859[95%confidence interval(CI):0.814-0.905]in the training cohort and 0.822(95%CI:0.717-0.927)in the testing *** to shapley additive explanations analysis,pancreatic texture,main pancreatic duct diameter,body mass index,estimated blood loss,and surgery time were the most important variables based on recursive feature *** CatBoost algorithm based on selected variables demonstrated superior performance,with an area under the receiver operating characteristic curve of 0.837(95%CI:0.788-0.886)in the training cohort and 0.812(95%CI:0.697-0.927)in the testing *** We developed the first machine learning-based predictive model for PPAP following *** predictive model can assist surgeons in an

关键词： Pancreaticoduodenectomy Postoperative complication Acute pancreatitis Machine learning Predictive value

Betaine combined with traditional Chinese medicine ointment to treat skin wounds in microbially infected diabetic mice

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World Journal of Diabetes 2025年第1期16卷 104-120页

作者： wen-yan Xu Yuan-Yuan Dai Shi-Xian yang Hao Chen yan-Qiang Huang Pei-Pei Luo Zhong-Heng Wei Guangxi Technology Innovation Cooperation Base of Prevention and Control Pathogenic Microbes with Drug Resistance Youjiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Guangxi Clinical Medical Research Center for Hepatobiliary Diseases Affiliated Hospital of Youjiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Department of Pathology Wannan Medical CollegeWuhu 241002Anhui ProvinceChina Guangxi Zhuang Autonomous Region Engineering Research Center of Clinical Prevention and Control Technology and Leading Drug for Microorganisms with Drug Resistance in Border Ethnic Areas Youjiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Department of Gastroenterology Wujin People’s Hospital Affiliated to Jiangsu UniversityChangzhou 213004Jiangsu ProvinceChina

BACKGROUND Skin wounds are highly common in diabetic patients,and with increasing types of pathogenic bacteria and antibiotic resistance,wounds and infections in diabetic patients are difficult to treat and *** To explore the effects of betaine ointment(BO)in promoting the healing of skin wounds and reducing the inflammation and apoptosis of skin cells in microbially infected diabetic *** By detecting the minimum inhibitory concentrations(MICs)of betaine and plant monomer components such as psoralen,we prepared BO with betaine as the main ingredient,blended it with traditional Chinese medicines such as gromwell root and psoralen,and evaluated its antibacterial effects and safety in vitro and in *** skin infection wound models of ordinary mice and diabetic mice were constructed,and the OTC drugs mupirocin ointment and Zicao ointment were used as controls to evaluate the antibacterial effects in vivo and the anti-inflammatory and anti-apoptotic effects of *** The MICs of betaine against microorganisms such as Staphylococcus aureus(***),Candida albicans and Cryptococcus neoformans ranged from 4 to 32μg/*** root and psoralea,both of which contain antimicrobial components,mixed to prepare BO with MICs ranging from 16 to 64μg/mL,which is 32-256 times lower than those of Zicao ointment,although the MIC is greater than that of *** 15 days of treatment with BO for USA300-infected ordinary mice,the wound scab removal rates were 83.3%,while those of mupirocin ointment and Zicao ointment were 66.7%and 0%,respectively,and the differences were statistically *** diabetic mice,the wound scab removal rate of BO and mupirolacin ointment was 80.0%,but BO reduced wound inflammation and the apoptosis of skin cells and facilitated wound *** The ointment prepared by mixing betaine and traditional Chinese medicine can effectively inhibit common skin microorganisms and has a strong effect on the skin wounds of sensit

关键词： Betaine ointment Staphylococcus aureus Drug resistance Skin infection Diabetes mellitus

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时空特征变分学习的交通流预测模型

控制理论与应用 2025年第1期42卷 158-166页

作者：欧阳毅汤文燕邵泳博黎晏伶浙江工商大学管理工程与电子商务学院浙江杭州310018

交通流量时空预测是智能交通系统的关键任务.针对城市交通流序列的非线性和多模态特性,本文提出了一种基于时空特征融合的变分学习模型(ST-FVAE),采用局部时空特征融合和全局特征融合两个阶段对具有图空间拓扑特性的交通流数据进行预测... 详细信息

交通流量时空预测是智能交通系统的关键任务.针对城市交通流序列的非线性和多模态特性,本文提出了一种基于时空特征融合的变分学习模型(ST-FVAE),采用局部时空特征融合和全局特征融合两个阶段对具有图空间拓扑特性的交通流数据进行预测.局部特征融合模块由时间卷积残差单元和图卷积神经网络(GCN)构成,提取交通节点的局部时间特征信息,并利用GCN将空间拓扑信息嵌入局部时间特征信息中.通过基于局部时空图特征融合的变分自编码器交通流预测模型,学习全局时空相关性特征.在全局时空特征融合变分自编码器的学习过程中,为使Q分布能够逼近实际数据P分布,通过最大化似然函数的变分推断证据下界(ELBO)使得两个分布之间的KL散度最小化,提出了计算分布期望的KL差异构造训练损失函数的方法,进一步提高预测准确率.通过对交通流数据集和交通速度数据集的预测实验结果表明:本文提出的方法在交通流量和速度的预测方面都具有较好的预测特性,对于30 min和60 min的预测鲁棒性更好.

关键词：交通流预测时空融合变分自编码器图卷积

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节能材料燃烧热值检测及影响因素研究

佛山陶瓷 2025年第1期35卷 101-103页

作者：闻艳元测检测技术(江苏)股份有限公司宿迁223800

本研究以岩棉板、复合发泡水泥板为例,探讨了节能材料燃烧热值检测过程中的影响因素。在研究中,详细阐述了每种材料的定义、特性和应用领域,并提出了相应的热值检测过程中的影响因素,包括试验过程环境、水温影响、称重误差、氧气纯度等... 详细信息

本研究以岩棉板、复合发泡水泥板为例,探讨了节能材料燃烧热值检测过程中的影响因素。在研究中,详细阐述了每种材料的定义、特性和应用领域,并提出了相应的热值检测过程中的影响因素,包括试验过程环境、水温影响、称重误差、氧气纯度等。通过重视这些关键因素,能够全面、准确地评估节能材料燃烧性能,为有效控制防火等级,以及在节能材料的选择和应用上提供了科学依据。

关键词：节能材料燃烧性能燃烧热值岩棉板复合发泡水泥板

基于MaxEnt模型的中国显齿蛇葡萄潜在适生区分析

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中国农业气象 2025年第2期46卷 213-225页

作者：周威钟艳雯陈玉贵李艳气象防灾减灾湖南省重点实验室长沙410118 湖南省气象服务中心长沙410118 湖南省气象信息中心长沙410118 中国气象局公共气象服务中心北京100081

基于中国显齿蛇葡萄现有193个地理分布数据和包括生物气候、海拔、辐射34个环境变量,利用最大熵模型(MaxEnt)模拟2041-2100年3种气候情景下显齿蛇葡萄潜在分布区及其变化,以期充分利用气候资源,为显齿蛇葡萄的种植、保护和产业发展等提... 详细信息

基于中国显齿蛇葡萄现有193个地理分布数据和包括生物气候、海拔、辐射34个环境变量,利用最大熵模型(MaxEnt)模拟2041-2100年3种气候情景下显齿蛇葡萄潜在分布区及其变化,以期充分利用气候资源,为显齿蛇葡萄的种植、保护和产业发展等提供科学参考。结果表明:(1)MaxEnt模型的模拟准确性较高,AUC值为0.928~0.956。(2)影响中国显齿蛇葡萄分布的6个关键环境因子为最干月降水量、最干季降水量、年降水量、5月月平均辐射、海拔和最冷月最低气温,高适生区的阈值分别为30~90mm、130~300mm、1600~2450mm、14000~15200KJ·m^(-2)·d^(-1)、<1100m和4.0~9.0℃。(3)可持续发展(SSP126)气候情景有利于增加显齿蛇葡萄的高、中适生区面积,2081-2100年显齿蛇葡萄适生区面积最大,为182.2万km^(2);局部发展(SSP245)气候情景下显齿蛇葡萄适生区面积增加效果低于可持续发展(SSP126)气候情景,但高于常规发展(SSP585)气候情景,主要表现在广东、广西、福建、云南和湖南的高适生区有所退化,四川东南部的中适生区增加;常规发展(SSP585)气候情景下,贵州、福建、广东和江西的部分高适生区逐步退化为中适生区,海南的中适生区退化为低适生区,全国的总适生区面积在2081-2100年为历史最低。(4)2041-2100年,显齿蛇葡萄总适生区面积仅在可持续发展(SSP126)气候情景下增加,在局部发展(SSP245)、常规发展(SSP585)气候情景下呈减少趋势;无论哪种气候情景,总适生区质心一致从目前的湖南、广西交界处向北略偏东方向移动46~80km至湖南省南部。

关键词：显齿蛇葡萄 MaxEnt模型适生区分析

锌和镍改性生物炭对环丙沙星的吸附降解性能与机制

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环境科学 2025年第2期46卷 923-933页

作者：张静江豪杨晓宇段文焱陈芳媛昆明理工大学环境科学与工程学院云南省土壤固碳与污染控制重点实验室昆明650500

改性生物炭具有较大的比表面积、可调节的孔隙结构和丰富的活性功能位点,使其能有效去除环境中的抗生素,但比较改性生物炭的不同性质对抗生素吸附降解的贡献缺乏系统研究.为明确金属浸渍改性生物的持久性自由基(PFRs)和微孔结构对环丙沙... 详细信息

改性生物炭具有较大的比表面积、可调节的孔隙结构和丰富的活性功能位点,使其能有效去除环境中的抗生素,但比较改性生物炭的不同性质对抗生素吸附降解的贡献缺乏系统研究.为明确金属浸渍改性生物的持久性自由基(PFRs)和微孔结构对环丙沙星(CIP)的吸附降解的贡献差异,在500℃和800℃热解条件下,制备了Ni改性和Zn改性的生物炭.500℃Ni改性(NCS500)明显提升了生物炭表面PFRs信号强度,而800℃Zn改性生物炭(ZCS800)比表面积得到显著提升(1 030.94 m^(2)·g^(-1)).与未改性生物炭相比,NCS500和ZCS800能够提高对CIP的最大吸附容量,使其分别达到78.68 mg·g^(-1)和190.07 mg·g^(-1),比对应的原始生物炭提升了3.35倍和24.83倍.乙腈萃取实验可区分两种改性生物炭CIP降解率在总去除率中的占比,Ni改性生物炭降解率最高,占总去除率的74.67%;而Zn改性生物炭的总去除率最高,但降解率仅占总去除率的52.63%,这是因为两种金属盐浸渍改性生物炭能产生羟基自由基(·OH)等活性氧物质有效降解CIP,但Ni改性生物炭其表面突出的PFRs信号能进一步直接与CIP反应高效降解CIP,而Zn改性生物炭较高的比表面积有利于疏水相互作用和π-π电子供体-受体与芳香分子的相互作用,显著提高了CIP的吸附.

关键词：持久性自由基(PFRs) 活性氧自由基(ROS) 金属盐浸渍改性抗生素降解