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Electron　Capture　into　Excited　States　in　Collision　between　Li－like　N^（4＋）　Ion　and　Na　Target

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IMP & HIRFL Annual Report 1994年 59-60页

作者： Liu Zhanwen Zhou Sixin Zhang wen Zhang Xuezhen Guo Xiaohong Ma Xinwen Yang Zhihu Liu Hui{3. zhao Mengchun wang Youde Li Dawan Yang Feng and Pan Guangyan({3. of physics, the chinese academy of sciences, beijing.)

ＥｌｅｃｔｒｏｎＣａｐｔｕｒｅｉｎｔｏＥｘｃｉｔｅｄＳｔａｔｅｓｉｎＣｏｌｌｉｓｉｏｎｂｅｔｗｅｅｎＬｉ－ｌｉｋｅＮ^（４＋）ＩｏｎａｎｄＮａＴａｒｇｅｔ￥ＬｉｕＺｈａｎｗｅｎ；ＺｈｏｕＳｉ... 详细信息

ＥｌｅｃｔｒｏｎＣａｐｔｕｒｅｉｎｔｏＥｘｃｉｔｅｄＳｔａｔｅｓｉｎＣｏｌｌｉｓｉｏｎｂｅｔｗｅｅｎＬｉ－ｌｉｋｅＮ^（４＋）ＩｏｎａｎｄＮａＴａｒｇｅｔ￥ＬｉｕＺｈａｎｗｅｎ；ＺｈｏｕＳｉｘｉｎ；ＺｈａｎｇＷｅｎ；Ｚｈａｎ?..

关键词： into Capture Excited Ion Li Na States Target and between

Therapeutic mechanisms of integrated traditional chinese and conventional medicine underlying its treatment of precancerous lesions of gastric cancer

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Journal of Traditional chinese Medicine 2022年第6期42卷 1023-1028页

作者： XU Qing wang Yang LI Zhongyu YAN Jiaxing zhao Yingpan wang {3. wen Yandong institute of Digestive Diseases Xiyuan Hospital of China Academy of Chinese Medical SciencesBeijing 100091China Eye Hospital of China academy of chinese Medical sciences Beijing 100040China

China has a high incidence of gastric cancer. Secondary prevention of gastric cancer is a major public health problem that must be solved urgently. Modern medicine focuses on the pathogenesis of precancerous lesions of gastric cancer(PLGC), and it has been found that there are a variety of abnormal gene expression patterns in PLGC. This study summarizes recent advances in our understanding of the therapeutic mechanisms of PLGC from various clinical studies;this will provide a reference for studying the therapeutic mechanisms of Traditional chinese Medicine in the treatment of PLGC from the combined points of view of Traditional chinese and Conventional medicine.

关键词： stomach neoplasms precancerous lesions mechanisms integrative medicine review

拥挤、抢食对自发性高血压大鼠发病的影响及作用机制的探讨

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心理学报 1989年第4期21卷 436-440页

作者：赵峰王文刘力生中国医学科学院心血管病研究所阜外医院中国医学科学院心血管病研究所阜外医院北京

社会、心理压力与疾病的发生、发展及转归有着密切的联系。而社会、心理压力为什么会导致一些心身疾病的发生?为什么可使一些疾病加重?尚无满意答案。本文选用自发性高血压大鼠(SHR),在实验室应激的条件下,对比观察了动物的血压,并对其... 详细信息

社会、心理压力与疾病的发生、发展及转归有着密切的联系。而社会、心理压力为什么会导致一些心身疾病的发生?为什么可使一些疾病加重?尚无满意答案。本文选用自发性高血压大鼠(SHR),在实验室应激的条件下,对比观察了动物的血压,并对其作用机制进行了初步探讨。发现:心理紧张状态可以导致有高血压遗传素质的SHR提前发病,而且可使病情不断加重;应激后SHR血浆神经递质(NE.E)和神经肽类物质(VIP)均明显增高。表明原发性高血压病的发生、发展与社会心理因素关系密切。

关键词：自发性高血压大鼠实验组对照组血浆 NE 试验组拥挤应激紧张性刺激血压调节动物 SHR 神经递质遗传素质抢食实验结果平均血压

Giant enhancement of magnetocaloric effect in metallic glass matrix composite

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Science China(physics,Mechanics & Astronomy) 2008年第4期51卷 337-348页

作者： wang YongTian BAI HaiYang PAN MingXiang zhao DeQian wang {3. institute of physics Chinese Academy of SciencesBeijing 100080China

The magnetocaloric effect (MCE) has made great success in very low temperature refrigeration, which is highly desirable for application to the extended higher tem-perature range. Here we report the giant enhancement of MCE in the metallic glass composite. The large magnetic refrigerant capacity (RC) up to 103.J·kg-1 is more than double the RC of the well-known crystalline magnetic refrigerant compound Gd5Si2Ge1.9Fe0.1 (3.7 J·kg-1) and MnFeP0.45As0.55 (3.0 J·kg-1)(containing either ex-orbitant-cost Ge or poisonous As). The full width at half maximum of the magnetic entropy change (ΔSm) peak almost spreads over the whole low-temperature range (from 3.3.to 3. K), which is five times wider than that of the Gd5Si2Ge1.9Fe0.1 and pure Gd. The maximum ΔSm approaches a nearly constant value in a wide tem-perature span over 100 K, and however, such a broad table-like region near room temperature has seldom been found in alloys and compounds. In combination with the intrinsic amorphous nature, the metallic glass composite may be potential for the ideal Ericsson-cycle magnetic refrigeration over a broad temperature range near room temperature.

关键词： metallic glass magnetocaloric effect composite

基于分析模型的青海湖近40年湖冰演变特征研究

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高原气象 2024年第5期43卷 1152-1162页

作者：唐鸿赵仪欣牛瑞佳文莉娟王梦晓中国科学院西北生态环境资源研究院冰冻圈科学与冻土工程重点实验室甘肃兰州730000 中国科学院青海湖综合观测研究站青海刚察812300 中国科学院大学北京100049 四川电力设计咨询有限责任公司四川成都610000

青藏高原湖泊分布广泛,且多为季节性冻结湖泊。在全球变暖的背景下,青藏高原湖冰厚度及其物候发生着显著变化,深刻影响着区域气候演变。然而目前对于高寒区湖冰厚度及其物候在气候学尺度上的演变特征认识还不甚清楚。因此,本文利用青海... 详细信息

青藏高原湖泊分布广泛,且多为季节性冻结湖泊。在全球变暖的背景下,青藏高原湖冰厚度及其物候发生着显著变化,深刻影响着区域气候演变。然而目前对于高寒区湖冰厚度及其物候在气候学尺度上的演变特征认识还不甚清楚。因此,本文利用青海湖下社水文站野外湖冰观测数据、MODIS湖冰覆盖率数据集、刚察气象站观测数据与CMFD数据,结合湖冰准稳态分析模型,研究了近40年(1979-2017年)青海湖湖冰厚度及其物候的演变特征。结果表明:模拟的多年冰厚平均值为0.3. m,与下社水文站实测值接近;模型对湖冰融化结束时间的刻画较准确,误差仅为0.07天,开始结冰时间和结冰期长度的误差分别为5.60天和5.67天。1979-2017年模拟的最大冰厚减小趋势与观测结果较为一致,即每年冰厚减少0.003.m。模拟的1979-2017年青海湖开始结冰时间延后(0.23.d·a^(-1)),融化结束时间提前(0.3. d·a^(-1)),结冰期长度缩短(1.02 d·a^(-1)),其中20世纪80年代结冰期缩短尤为明显(2.2 d·a^(-1))。1979-2017年青海湖结冰期内(12月至次年4月)向下长波辐射和气温(二者均呈现上升趋势)与平均冰厚以及最大冰厚之间存在显著的负相关关系,向下短波辐射(呈现下降趋势)与最大冰厚以及平均冰厚之间存在显著的正相关关系。去趋势敏感性试验表明:向下长波辐射、气温、向下短波辐射、比湿是青海湖1979-2017年内平均冰厚和最大冰厚变率的主要驱动因子,对平均冰厚变率分别贡献了42.08%,40.93.,-3..99%和17.45%,对最大冰厚变率分别贡献了44.48%,44.68%,-3..77%和19.92%。所有气象驱动因子对二者贡献了83.40%和87.01%,可以看出青海湖最大冰厚变率相较平均冰厚变率更容易受到气象条件的影响。本文研究结果对冰冻圈湖冰的长期演变趋势提供了认识,为其他青藏高原湖泊冷季研究提供了参考依据。

关键词：青海湖准稳态湖冰模型湖冰厚度湖冰物候

基于气液两相地热源的ORC发电系统工质筛选

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动力工程学报 2024年第1期44卷 68-75页

作者：赵斌温柔边技超刘瑞龚宇烈王善民长沙理工大学能源与动力工程学院长沙410114 北京电力设备总厂有限公司北京102401 中国科学院广州能源研究所广州510640 西藏地热产业协会拉萨850000

针对以热源温度为140℃的气液两相混合地热流体为热源驱动的有机朗肯循环(ORC)发电系统最佳工质筛选问题,选取6种干工质,通过在MATLAB中搭建系统模型,分析了各工质蒸发温度对系统热力性能的影响,对比了不同蒸气质量分数下最佳蒸发温度... 详细信息

针对以热源温度为140℃的气液两相混合地热流体为热源驱动的有机朗肯循环(ORC)发电系统最佳工质筛选问题,选取6种干工质,通过在MATLAB中搭建系统模型,分析了各工质蒸发温度对系统热力性能的影响,对比了不同蒸气质量分数下最佳蒸发温度随热源温度的变化规律,并研究了热源质量流量对系统净输出功率的影响以及蒸发温度对回灌温度的影响。结果表明:综合考虑工质的热力性能、物理化学稳定性、热源匹配性以及回灌温度对地热ORC发电系统的影响,工质R601a(异戊烷)可作为以140℃气液两相混合地热流体为热源驱动的ORC发电系统的最佳适用工质。

关键词：地热电站有机朗肯循环性能分析有机工质筛选

Tenecteplase versus alteplase in treatment of acute ST-segment elevation myocardial infarction:A randomized non-inferiority trial

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chinese Medical Journal 2024年第3期137卷 312-319页

作者： Xingshan zhao Yidan Zhu Zheng Zhang Guizhou Tao Haiyan Xu Guanchang Cheng wen Gao Liping Ma Liping Qi Xiaoyan Yan Haibo {3. Qingde Xia Yu{3. Yang Wanke Li Juwen Rong Limei {3. Yutian Ding Qiang Guo Wanjun Dang Chen Yao Qin Yang Runlin Gao Yangfeng Wu Shubin Qiao Department of Cardiology Beijing Jishuitan HospitalCapital Medical UniversityThe Fourth Clinical Medical College of Peking UniversityBeijing 100035China Peking University Clinical Research institute Peking University First HospitalBeijing 100191China Department of Cardiology The First Hospital of Lanzhou UniversityLanzhouGansu 730013China Department of Cardiology The First Affiliated Hospital of Liaoning Medical UniversityJinzhouLiaoning 110002China Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100037China Department of Cardiology Huaihe Hospital of Henan UniversityKaifengHenan 450001China Department of Cardiology Bayannur HospitalBayannurInner Mongolia 015208China Department of Cardiology Puyang People’s HospitalPuyangHenan 457099China Department of Cardiology Xingtai Third HospitalXingtaiHebei 054099China Department of Cardiology Lintao County People’s HospitalDingxiGansu 730599China Department of Cardiology Dancheng County People’s HospitalZhoukouHenan 477150China Department of Cardiology The First People’s Hospital of LingbaoSanmenxiaHenan 472500China Department of Cardiology Shanyin County People’s HospitalShuozhouShanxi 036999China Department of Cardiology Uxin Banner People’s HospitalOrdosInner Mongolia 017399China Department of Cardiology Lingqiu County People’s HospitalDatongShanxi 034499China Department of Cardiology Huaibin County People’s HospitalXinyangHenan 464411China Department of Cardiology Tianzhu County People’s HospitalWuweiGansu 733200China Guangzhou Recomgen Biotech Co. LtdGuangzhouGuangdong 510530China

Background:A phase II trial on recombinant human tenecteplase tissue-type plasminogen activator(rhTNK-tPA)has previously shown its preliminary efficacy in ST elevation myocardial infarction(STEMI)*** study was designed as a pivotal postmarketing trial to compare its efficacy and safety with rrecombinant human tissue-type plasminogen activator alteplase(rt-PA)in chinese patients with ***:In this multicenter,randomized,open-label,non-inferiority trial,patients with acute STEMI were randomly assigned(1:1)to receive an intravenous bolus of 16 mg rhTNK-tPA or an intravenous bolus of 8 mg rt-PA followed by an infusion of 42 mg in 90 *** primary endpoint was recanalization defined by thrombolysis in myocardial infarction(TIMI)flow grade 2 or *** secondary endpoint was clinically justified *** endpoints included 3.-day major adverse cardiovascular and cerebrovascular events(MACCEs)and safety ***:From July 2016 to September 2019,767 eligible patients were randomly assigned to receive rhTNK-tPA(n=3.4)or rt-PA(n=3.3..Among them,3.9 patients had coronary angiography data on TIMI flow,and 711 patients had data on clinically justified *** used a–15%difference as the non-inferiority efficacy *** comparison to rt-PA,both the proportion of patients with TIMI grade 2 or 3.flow(78.3.[148/189]vs.81.7%[147/180];differences:–3.4%;95%confidence interval[CI]:–11.5%,4.8%)and clinically justified recanalization(85.4%[3.5/3.7]vs.85.9%[3.4/3.4];difference:–0.5%;95%CI:–5.6%,4.7%)in the rhTNK-tPA group were *** occurrence of 3.-day MACCEs(10.2%[3./3.4]vs.11.0%[42/3.3.;hazard ratio:0.96;95%CI:0.61,1.50)did not differ significantly between *** safety outcomes significantly differed between ***:rhTNK-tPA was non-inferior to rt-PA in the effect of improving recanalization of the infarct-related artery,a validated surrogate of clinical outcomes,among chinese patients with acute ***

关键词： Thrombolytic therapy rhTNK-tPA Randomized controlled trial ST elevation myocardial infarction

60%SiCp/2009铝基复合材料表面等离子体电解氧化膜的生长和表征

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Transactions of Nonferrous Metals Society of China 2024年第2期34卷 435-452页

作者：廖燚钊王兴平高川力周茜徐驰金小越杜建成薛文斌张永忠北京师范大学核科学与技术学院射线束技术教育部重点实验室北京100875 北京市科学技术研究院辐射技术研究所北京100875 中国有研科技集团有限公司北京100088

在硅酸盐溶液中采用等离子体电解氧化技术在60%SiCP(体积分数)/2009铝基复合材料表面制备陶瓷膜。研究氧化膜的显微组织、成分、润湿性及其耐腐蚀性能,探讨SiC颗粒表面火花放电的产生机理。结果表明,来自硅酸盐溶液的不溶性化合物(SiO_(... 详细信息

在硅酸盐溶液中采用等离子体电解氧化技术在60%SiCP(体积分数)/2009铝基复合材料表面制备陶瓷膜。研究氧化膜的显微组织、成分、润湿性及其耐腐蚀性能,探讨SiC颗粒表面火花放电的产生机理。结果表明,来自硅酸盐溶液的不溶性化合物(SiO_(2))使SiC颗粒表面产生火花放电,Al-Si-O化合物中的缺陷为SiC颗粒表面放电电流的传导提供优先路径。1200s时铝基复合材料表面形成5.5μm厚的均匀膜层,膜层的表面自由能在40s时达到最大值3..10 m J/cm^(2),并在1200 s时下降到25.95 m J/cm^(2)。此外,等离子体电解氧化处理可以显著提高复合材料的耐蚀性。

关键词：等离子体电解氧化铝基复合材料 SiC增强颗粒火花放电润湿性耐蚀性

Characterization of acute-on-chronic liver diseases: A multicenter prospective cohort study

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World Journal of Hepatology 2024年第5期16卷 809-821页

作者： Yuan-Yao Zhang Sen Luo Hai Li Shu-Ning Sun Xian-Bo wang Xin Zheng Yan Huang Bei-Ling Li Yan-Hang Gao Zhi-ping Qian Feng Liu Xiao-Bo Lu Jun-ping Liu Hao-Tang Ren Yu-Bao Zheng Hua-Dong Yan Guo-Hong Deng Liang Qiao Yan Zhang {3.-Yi Gu Xiao-Mei Xiang Yi Zhou Yi-Xin Hou Qun Zhang Yan Xiong Cong-Cong Zou Jun Chen Ze-Bing Huang Xiu-Hua Jiang Ting-Ting Qi Yuan-Yuan Chen Na Gao Chun-Yan Liu Wei Yuan Xue Mei Jing Li Tao Li Rong-Jiong Zheng Xin-Yi Zhou Jun {3. Zhong-Ji Meng Department of Infectious Disease Institute of Biomedical ResearchRegulatory Mechanism and Targeted Therapy for Liver Cancer Shiyan Key LaboratoryHubei provincial Clinical Research Center for Precise Diagnosis and Treatment of Liver CancerTaihe HospitalHubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Gastroenterology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200120China Department of Infectious Diseases Southwest HospitalThe Third Military Medical University(Army Medical University)Chongqing 400000China Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100020China Department of Infectious Diseases Institute of Infection and ImmunologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430020Hubei ProvinceChina Department of Infectious Diseases Hunan Key Laboratory of Viral HepatitisXiangya HospitalCentral South UniversityChangsha 110051Hunan ProvinceChina Hepatology Unit Department of Infectious DiseasesNanfang HospitalSouthern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of Hepatology The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Liver Intensive Care Unit Shanghai Public Health Clinical CentreFudan UniversityShanghai 200093China Tianjin institute of Hepatology Nankai University Second People's HospitalTianjin 300192China Infectious Disease Center The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi 830054Xinjiang Uygur Autonomous RegionChina Department of Infectious Diseases and Hepatology The Second Hospital of Shandong UniversityJinan 250000Shandong ProvinceChina State Key Laboratory for Diagnosis and Treatment of Infectious Diseases Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseaseThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Infectious Diseases The Thir

BACKGROUND Acute-on-chronic liver disease(AoCLD)accounts for the majority of patients hospitalized in the Department of Hepatology or Infectious *** To explore the characterization of AoCLD to provide theoretical guidance for the accurate diagnosis and prognosis of *** Patients with AoCLD from the chinese Acute-on-Chronic Liver Failure(ACLF)study cohort were included in this *** clinical characteristics and outcomes,and the 90-d survival rate associated with each clinical type of AoCLD were analyzed,using the Kaplan-Meier method and the log-rank *** A total of 3.75 patients with AoCLD were enrolled,including 1679(49.7%)patients with liver cirrhosis acute decompensation(LC-AD),850(25.2%)patients with ACLF,577(17.1%)patients with chronic hepatitis acute exacer-bation(CHAE),and 269(8.0%)patients with liver cirrhosis active phase(LC-A).The most common cause of chronic liver disease(CLD)was HBV infection(71.4%).The most common precipitants of AoCLD was bacterial infection(22.8%).The 90-d mortality rates of each clinical subtype of AoCLD were 43.4%(23./53.)for type-C ACLF,3..0%(3./100)for type-B ACLF,27.0%(58/215)for type-A ACLF,9.0%(151/1679)for LC-AD,3.0%(8/269)for LC-A,and 1.2%(7/577)for *** HBV infection is the main cause of CLD,and bacterial infection is the main precipitant of *** most common clinical type of AoCLD is *** diagnosis and timely intervention are needed to reduce the mortality of patients with LC-AD or ACLF.

关键词： Acute-on-chronic liver disease Acute-on-chronic liver failure Liver cirrhosis Clinical features Prognosis