检索结果-南通市图书馆

Improving Thermal-oxidative Aging Resistance of Styrene-butadiene Rubber by Antioxidant Loaded Silica Aerogel

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第8期42卷 1198-1209页

作者： Xue-Fei Ping Yu Wang Lu liu fu-Yong liu Hong-Wei He Pi Wang wen-wen Yu qiang Zheng College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering Taiyuan 030032China Key Laboratory of Macromolecular Synthesis and functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310058China

The antioxidant N-isopropyl-N'-phenyl-p-phenylenediamine(4010NA)was dissolved in ethanol and impregnated into silica aerogel(SAG)via vacuum-pressure cycles,yielding composite particles(A-N)with enhanced sustained-release and reinforcing *** effect of A-N on the mechanical properties and thermal-oxidative aging resistance of styrene-butadiene rubber(SBR)vulcanizates was *** and BET assessments indicated that the loading efficiency of 4010NA in SAG reached 14.26%within ethanol's solu bility *** A-N into SBR vulcanizates significantly elevated tensile strength by 17.5%and elongation at break by 41.9%over those with fumed silica and ***,A-N notably enhanced the thermal-oxidative aging resistance of *** aging for 96 h at 100℃,the tensile strength and elongation at break of SBR with A-N sustained 70.09%and 58.61%of their initial values,respectively,with the retention rate of elongation at break being 62.8%higher than that of SBR with fumed silica and free *** study revealed that A-N composite particles significantly inhibited the crosslinking in SBR's molecular chains,reducing hardening and embrittlement during later thermal-oxidative aging stages.

关键词： Styrene-butadiene rubber Silica aerogel Loading modification Thermal-oxidative aging

Molecular docking-aided AIEgen design: concept, synthesis and applications

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第8期67卷 2614-2628页

作者： Jian-Qing Zhang Xiao-Yu Xu fu-Sheng liu Shu-qiang Cao Yu-Xin Gui Yi-wen Su Xiao-Yu He Ji-Yuan Liang You-Quan Zou Department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversitySchool of Pharmaceutical SciencesWuhan UniversityWuhan 430071China Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of EducationWuhan UniversityWuhan 430071China Tai Kang Center for Life and Medical Sciences Wuhan UniversityWuhan 430071China Department of Hepatobiliary Pancreatic SurgeryZhongnan Hospital of Wuhan UniversityWuhan 430071China

Aggregate-induced emission luminogens(AIEgens) have been widely used in biological imaging, chemical sensing, and disease treatments. The rational design and construction of AIEgens have received considerable research interests during the last few years. Herein, molecular docking-aided AIEgen design has been reasonably proposed and AIEgen TBQZY with excellent ~1O_(2) generation ability has been synthesized. The newly developed TBQZY could efficiently kill S. epidermidis and methicillinresistant S. epidermidis(MRSE) by tightly binding to bacteria and triggering the accumulation of ~1O_(2) in bacteria. TBQZY specifically regulated the immune system and polarized macrophages from M1 to M2 to accelerate the elimination of biofilm in vivo. In addition, healing acceleration was observed in chronic wounds treated with TBQZY, and side effects were ***, TBQZY had extraordinary potential for combating drug-resistant bacteria in the clinical setting. This research not only provided new concepts for the design of AIEgens, but also shed some lights on the discovery of drugs against drug-resistant bacteria.

关键词： AIEgen molecular docking drug-resistant bacteria biofilm chronic wounds healing

Effect and Safety of Herbal Medicine Foot Baths in Patients with Diabetic Peripheral Neuropathy:A Multicenter Double-Blind Randomized Controlled Trial

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2024年第3期30卷 195-202页

作者： HUANG Hao-yue LIN Yu-ping WEI Hua fu Yu ZHOU Yue-hong FANG Zhao-hui QIU Xiao-tang WANG Mei LI Qing-bo LI Shan-shan WANG Shi-dong dai Fang liu Zhen-jie ZHAO Ling wen Jian-xuan WU Li-yan ZENG Hui-yan ZHANG Jin-ming LU Qi-yun HE liu SONG Wei SUN Lu LUO Lu-lu HE Jia-li XIE wen-wen LIANG Qing-shun HUANG Yuan ZHU Sheng-ling LONG Jie-er GAO Zhi-juan wen Ze-huai LI Chun-ji OUYANG wen-wei LI Geng WU Ming-hui LI An-xiang HUANG Jin-zhu Sanjoy K Paul TANG Xian-yu FAN Guan-jie Department of Endocrinology Guangdong Provincial Hospital of Chinese MedicineGuangzhou510120China The Second Clinical College of Guangzhou University of Chinese Medicine Guangzhou510120China Department of Endocrinology The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou510120China Guangdong Provincial Academy of Chinese Medical Sciences Guangzhou510120China Department of Endocrinology The First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou450000China Department of Endocrinology Liuyang Hospital of Chinese MedicineChangsha410000China Department of Endocrinology The First Affiliated Hospital of Anhui University of Chinese MedicineHefei230000China Department of Endocrinology Hainan Provincial Hospital of Traditional Chinese MedicineHaikou570100China Department of Endocrinology The Affiliated Hospital of Liaoning University of Traditional Chinese MedicineShenyang110000China Department of Geriatric Luoyang No.1 Hospital of Traditional Chinese MedicineLuoyangHenan Province471000China Department of Endocrinology The Second Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Department of Endocrinology Beijing University of Chinese Medicine Affiliated Dongzhimen HospitalBeijing100000China Department of Endocrinology The First Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Melbourne EpiCentre The University of Melbourne and Melbourne HealthMelbourne3013Australia

Objective:To evaluate the effect and safety of foot baths with Tangbi Waixi Decoction(TW)in treating patients with diabetic peripheral neuropathy(DPN).Methods:It is a multicenter double-blinded randomized controlled *** with DPN were recruited between November 18,2016 and May 30,2018 from 8 hospitals in *** patients received basic treatments for glycemic *** received foot baths with TW herbal granules either 66.9 g(intervention group)or 6.69 g(control group)for 30 min once a day for 2 weeks and followed by a 2-week rest,as a therapeutic *** the Toronto Clinical Scoring System total score(TCSS-TS)6 points,the patients received a total of 3 therapeutic courses(for 12 weeks)and were followed up for 12 *** primary outcome was change in TCSS-TS score at 12 and 24 *** outcomes included changes in bilateral motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of the median and common peroneal *** was also ***:Totally 632 patients were enrolled,and 317 and 315 were randomized to the intervention and control groups,*** the 12-week intervention,patients in both groups showed significant declines in TCSSTS scores,and significant increases in MNCV and SNCV of the median and common peroneal nerves compared with pre-treatment(P0.05),and no serious adverse event was related with ***:Treatment of TW foot baths was safe and significantly benefitted patients with DPN.A low dose of TW appeared to be more effective than a high dose.(Registry *** CTR-IOR-16009331)

关键词： diabetic peripheral neuropathy herbal medicine foot baths Chinese medicine randomized controlled trial Tangbi Waixi Decoction

A multicenter prospective study on the management of hepatoblastoma in children:a report from the Chinese Children's Cancer Group

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2024年第6期20卷 590-601页

作者： Meng-Jie Tang Xiao-Li Ma Xiang-Ling He Wei-Hua Pan Xiao-Hong Zhang Sha-Yi Jiang Ju Gao fu Li Wei Yao Song Gu Wei-Ling Zhang qiang Zhao Shi-Hao Huang Yong-Jun Fang Wei liu Hui-Zhong Niu Chun-Mei Wang Li-Rong Sun Hui Gao Yun-Peng dai shun-Gen Huang Zhi-Yong Zhong Xi-Ge Wang Zhong-Rong Li Liang-Chun Yang Ye-Ming Wu Huan-Min Wang Xin Sun Xiao-Jun Yuan Department of Pediatric Hematology/Oncology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineNo.1665Kongjiang RoadYangpu DistrictShanghai 200092China Medical Oncology Department Pediatric Oncology CenterBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Hematology/Oncology Children's Medical CenterHunan Provincial People's HospitalThe First Affiliated Hospital of Hunan Normal UniversityChangsha 41005China Department of Pediatric Surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Hematology/Oncology Guangzhou Women and Children's Medical CenterNational Children's Medical Center for South Central RegionGuangzhou 510623China Department of Hematology Shanghai Children's HospitalShanghai Jiao Tong UniversityShanghai 200062China Department of Pediatrics West China Second University HospitalSichuan UniversityChengdu 610041China Department of Hematology/Oncology Qilu Children's Hospital of Shandong UniversityJinan 250022China Department of Pediatric Surgery Children's Hospital of Fudan UniversityShanghai 201102China Department of General Surgery Shanghai Children's Medical Center(National Children's Medical Center-Shanghai)Shanghai Jiao Tong University School of MedicineShanghai 200127China Department of Pediatrics Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Pediatric Oncology Tianjin Medical University Cancer Institute and HospitalTianjin 300060China Department of Hematology/Oncology Children's Hospital of Nanjing Medical UniversityNanjing 210008China Department of Hematology/Oncology Henan Children's HospitalZhengzhou 450018China Department of Pediatric General Surgery Hebei Children's Hospital of Hebei Medical UniversityShijiazhuang City 050031China Children's Hospital the First Affliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of Paediatric

Background This study aimed to identify survival risk factors in Chinese children with hepatoblastoma(HB)and assess the effectiveness of the new treatment protocol proposed by the Chinese Children's Cancer Group(CCCG)in *** A multicenter,prospective study that included 399 patients with HB from January 2015 to June 2020 was *** demographics,treatment protocols,and other related information were *** regression models and Kaplan-Meier curve methods were *** The 4-year event-free survival(EFS)and overall survival(OS)were 76.9 and 93.5%,*** 4-year EFS rates for the very-low-risk,low-risk,intermediate-risk,and high-risk groups were 100%,91.6%,81.7%,and 51.0%,*** 4-year 0S was 100%,97.3%,94.4%,and 86.8%,*** regression analysis found that age,tumor rupture(R+),and extrahepatic tumor extension(E+)were independent prognostic factors.A total of 299 patients had complete remission,and 19 *** with declining alpha-fetoprotein(AFP)>75%after the first two cycles of neoadjuvant chemotherapy had a better EFS and OS than those≤75%.Conclusions The survival outcome of HB children has dramatically improved since the implementation of CCCG-HB-2016 ***≥8 years,R+,and E+were independent risk factors for *** with a declining AFP>75%after the first two cycles of neoadjuvant chemotherapy had better EFS and OS.

关键词： Alpha-fetoprotein Hepatoblastoma Multicenter Prospective study Survival

Frontiers in high entropy alloys and high entropy functional materials

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第10期43卷 4639-4776页

作者： wen-Tao Zhang wen Huang fu-Jie Yu Qi Zhao Xin-Dong Zhu Tao Feng Yao Jiang Xiao-Ming Li Xue-Fei Miao He Zhu Si Lan Xue-Qian Wang Bao-Long Shen Zhe Jia Feng-Qi Zhang Wei Wang Qi liu Yang Ren Xun-Li Wang Xiao-Ya Cui Xiao-Yang Wang Ya-Nan Chen Bing-Bing Fan Meng-Ru Li Qi-Long Gao Jia-Ming Guo Zeng-Bao Jiao Zhi-Min Guo Yu-Ping Zhao Qian Yu Rui Huang Ling-Kun Zhang Yi-Ping Lu Xu-Bo Li Huai-Jun Lin Yan Ma Wei-Ming Yang Zhi-Hua Shen Hai-Yan He Yong-Gang Sun Yong-Jiang Huang De-Zhuang Wang Qing-Feng liu Fei-Yang Wang Hui liu Hong-Hui Wu Li-qiang Wang Yang Lu Nan Wang Tian-Li Wang Wei-Bing Liao Yi-Han Wang Yuan Wu Yu-Zhen Yin Jie Pan Yi Zhang Qing Wang Jian-Yang Zhang Tao Yang Yasir Sohail Jin-Yu Zhang Hua Ji qiang Li Wei-Di liu Zhi-Gang Chen Xiong-Jun liu wen Ma Liang Mao Zhen-Duo Wu School of Materials Science and Engineering Nanjing University of Science and Technology Jiangsu Key Laboratory for Advanced Metallic Materials School of Materials Science and Engineering Southeast University Department of Physics City University of Hong Kong School of Materials Science and Engineering Tianjin University School of Physics and Microelectronics Zhengzhou University Department of Mechanical Engineering Research Institute for Advanced Manufacturing The Hong Kong Polytechnic University Center of Electron Microscopy and State Key Laboratory of Silicon Materials School of Materials Science and Engineering Zhejiang University Key Laboratory of Solidification Control and Digital Preparation Technology (Liaoning Province) School of Materials Science and Engineering Dalian University of Technology Institute of Advanced Wear & Corrosion Resistance and functional Materials Jinan University School of Mechanics and Civil Engineering China University of Mining and Technology School of Physical Sciences Great Bay University School of Materials Science andEngineering Harbin Institute of Technology State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Beijing Advanced Innovation Center for Materials Genome Engineering Research Institute for Carbon Neutrality University of Science and Technology Beijing Department of Mechanical Engineering The University of Hong Kong School of Computing Macquarie University Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic Engineering Shenzhen University State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing State Key Laboratory of Materials Processing and Die & Mould Technology School of Materials Science and Engineering Huazhong University of Science and Technology Institute of materials Shanghai University Department of Materials Science and Engineering C

Owing to their exceptional properties, high-entropy alloys(HEAs) and high-entropy materials have emerged as promising research areas and shown diverse applications. Here,the recent advances in the field are comprehensively reviewed,organized into five sections. The first section introduces the background of HEAs, covering their definition, significance,application prospects, basic properties, design principles, and microstructure. The subsequent section focuses on cutting-edge high-entropy structural materials, highlighting developments such as nanostructured alloys, grain boundary engineering,eutectic systems, cryogenic alloys, thin films, micro-nano-lattice structures, additive manufacturing, high entropy metallic glasses, nano-precipitate strengthened alloys, composition modulation, alloy fibers, and refractory systems. In the following section, the emphasis shifts to functional materials, exploring HEAs as catalysts, magneto-caloric materials, corrosion-resistant alloys, radiation-resistant alloys, hydrogen storage systems, and materials for biomedicine. Additionally, the review encompasses functional high-entropy materials outside the realm of alloys, including thermoelectric, quantum dots, nanooxide catalysts, energy storage materials, negative thermal expansion ceramics,and high-entropy wave absorption materials. The paper concludes with an outlook, discussing future directions and potential growth areas in the field. Through this comprehensive review,researchers, engineers, and scientists may gain valuable insights into the recent progress and opportunities for further exploration in the exciting domains of high-entropy alloys and functional materials.

关键词： Cutting-edge structural materials Cutting-edgefunctional materials High entropy alloys

Sleep disturbances and psychomotor retardation in the prediction of cognitive impairments in patients with major depressive disorder

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2024年第10期14卷 1474-1483页

作者： Mi Wang wen-Tao Chen Hao-Ting Wang Bang-Shan liu Yu-Meng Ju qiang-Li Dong Xiao-wen Lu Jin-Rong Sun Liang Zhang Hua Guo fu-Tao Zhao Wei-Hui Li Li Zhang Ze-Xuan Li Mei Liao Yan Zhang Jin liu Ling-Jiang Li Department of Mental Health Center Xiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina National Clinical Research Center of Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina Department of Psychiatry National Clinical Research Center for Mental DisordersThe Second Xiangya Hospital of Central South UniversityChangsha 410011Hunan ProvinceChina Department of Psychiatry Zhumadian Psychiatric HospitalZhumadian 463000Henan ProvinceChina

BACKGROUND Symptoms of depression and comorbid anxiety are known risk factors for cognitive impairment in major depressive disorder(MDD).Understanding their relationships is crucial for developing targeted interventions to mitigate cognitive impairments in MDD *** expect that the severity of sleep disturbances and other depressive symptoms will be positively correlated with the degree of cognitive *** also hypothesize that anxiety symptoms,especially psychic anxiety,is a key factor in predicting cognitive performance in MDD patients and may indirectly contribute to cognitive impairment by affecting sleep disturbances and other potential *** To determine which dimension of the depressive and anxiety symptoms predicts cognitive impairment during a depressive *** A comprehensive neurocognitive test battery assessed executive function,attention,processing speed,and memory in 162 medication-free MDD patients and 142 matched healthy *** 24-item Hamilton Depression Rating Scale was used to assess depressive symptoms,and the 14-item Hamilton Anxiety Scale was used to assess anxiety *** regression analyses and mediation analyses were conducted to evaluate the impact of depressive and anxiety symptoms,as well as their interactions,on cognitive *** Among the depressive symptoms,sleep disturbances were associated with poorer executive function(P=0.004),lower processing speed(P=0.047),and memory impairments(Pfunction[β=-0.013,BC CI(-0.027,-0.001)]and memory[β=-0.149,BC CI(-0.237,-0.063)],while PR mediated its ef

关键词： Major depressive disorder Cognitive impairment Depressive symptoms Anxiety symptoms Sleep disturbance Psychomotor retardation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

豪华邮轮结构设计特点与分类设计技术

船海工程 2024年第1期53卷 97-101页

作者：高处刘文夫邱伟强陈涛中国船舶及海洋工程设计研究院上海200011

考虑到现代豪华邮轮已经由传统意义上的远洋交通工具演变为海上休闲娱乐的重要载体,设施齐全,功能多样,可以容纳更多游客的高、大、长上层建筑成为豪华邮轮最显著的特点,通过分析豪华邮轮多甲板、长上层建筑船体结构的静力及动力响应规... 详细信息

考虑到现代豪华邮轮已经由传统意义上的远洋交通工具演变为海上休闲娱乐的重要载体,设施齐全,功能多样,可以容纳更多游客的高、大、长上层建筑成为豪华邮轮最显著的特点,通过分析豪华邮轮多甲板、长上层建筑船体结构的静力及动力响应规律,总结出豪华邮轮船体平均应力水平低、高应力区域多、板薄易屈曲、振动噪声分布不均衡的整体特点,从顶层设计的角度提出分类设计技术。

关键词：豪华邮轮结构设计结构分类设计

Phase transformation behaviors and mechanical properties of Ti_(50)Ni_(49)Fe_1 alloy with severe plastic deformation

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2013年第5期32卷 448-452页

作者： wen Ma Bin Chen fu-shun liu Qing Xu Division of Science and Technology Information General Research Institute for Nonferrous Metals School of Material Science and Engineering Beijing University of Aeronautics and Astronautics Metrology and Phsico-Chemical Institute Capital Aerospace Machinery Company

In this work, transformation behaviors and mechanical properties of cold-rolled shape memory alloy TisoNia9Fel by severe plastic deformation （SPD） were intensively investigated. The phase transformation behaviors, phase analysis, and microstructures were characterized by differential scanning calorimetry （DSC）, X-ray diffraction （XRD）, and transmission electron microscopy （TEM）, respectively. Tensile testing was performed to analyze the effect of SPD on the mechanical properties and shape memory of TisoNi49Fel alloy. When the thickness reduction is beyond 30 %, the martensitic transformation is suppressed. After cold-rolling, the alloy is mainly com- posed of B2 parent phases with some stress-induced martensitic B 19t phases, and high density of dislocations are generated and the grains are obviously refined. The yield stress ab significantly raises from 618 MPa of 0 % cold rolling to 1,338 MPa of 50 % SPD. Shape-memory effect increases from 6.5 % without cold rolling to 8.5 % after 30 % SPD, ascribed to the induced defects in cold rolling. Those results indicate that TisoNi49Fel alloy has improved mechanical properties and potential commercial applications after SPD.

关键词： TiNiFe alloy Cold-rolling Severe plasticdeformation (SPD) Shape memory effect

基于CFD-DEM方法的饱和砂土场地液化模拟研究

在线全文

学校读者我要写书评

暂无评论

岩土力学 2024年第8期45卷 2492-2501,2514页

作者：许文昊王志华申志福高洪梅刘殷强张鑫磊南京工业大学岩土工程研究所江苏南京211816 河海大学江苏省交通基础设施安全保障技术工程研究中心江苏南京211816

砂土液化是常见的地震灾害,目前应用于研究砂土液化动力特性的室内试验以及模型试验还不能全面反映土体液化全过程。计算流体动力学(computational fluid dynamics,CFD)与离散元法(discrete element method,DEM)耦合模拟方法能够准确地... 详细信息

砂土液化是常见的地震灾害,目前应用于研究砂土液化动力特性的室内试验以及模型试验还不能全面反映土体液化全过程。计算流体动力学(computational fluid dynamics,CFD)与离散元法(discrete element method,DEM)耦合模拟方法能够准确地模拟各类水土耦合问题。通过二次开发的CFD-DEM流固耦合模块实现离散元软件PFC3D与计算流体力学软件OpenFOAM之间的力学信息交互,利用颗粒水下自由沉降验证该方法的可行性。利用PFC3D软件模拟室内循环三轴试验标定出具有真实饱和砂土动力特性的数值砂样。根据已有的参数信息以及耦合模拟方法建立了饱和砂土的场地液化模型。模拟结果表明,离散元法能够复现室内砂土液化试验,标定参数可应用于场地液化模拟;单颗粒沉降速度与理论解一致验证了CFD-DEM耦合方法的准确性;峰值加速度0.25g下不同深度处土体均会发生液化,液化时超孔压比无法达到1,超孔压累计值由浅层往深层递增;液化后土体强度自下而上逐渐恢复,再固结的场地土体结构呈现均匀化发展趋势。

关键词：砂土液化 CFD-DEM耦合方法颗粒自由沉降场地液化模拟