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中国共产党处理民族问题的百年历程及启示

兵团党校学报 2024年第3期208卷 101-112页

作者：李宛芸第十三师新星市党委党校(行政学院) 新疆哈密839099

纵观党处理民族问题的百年历程,呈现出一脉相承、与时俱进的理论实践连续性与动态性特点。新民主主义革命时期探索出维护团结加固统一的民族区域自治,建立信任体现尊重的民族平等原则;社会主义革命和建设时期奠定基础,摸清中国多民族现... 详细信息

纵观党处理民族问题的百年历程,呈现出一脉相承、与时俱进的理论实践连续性与动态性特点。新民主主义革命时期探索出维护团结加固统一的民族区域自治,建立信任体现尊重的民族平等原则;社会主义革命和建设时期奠定基础,摸清中国多民族现实情况,使革命时期成功经验落地生根,同时推进适合社会主义制度的民族工作系列实践;改革开放新时期实现由经验主导的民族工作横向发展向以理论体系为支撑的纵向成长;进入新时代全方位把握国情,抓住“中华民族共同体”这个着力点,正本清源坚定中国特色解决民族问题的道路自信,实现党的民族工作向纵深推进。百年历程启示我们:党的领导贯穿始终;马克思主义民族理论与中国具体实际相结合贯穿始终;中华民族团结进步历史发展规律贯穿始终;人民立场贯穿始终。

关键词：中国共产党百年实践民族问题民族工作

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青皮红心柚新品种云青1号的选育

果树学报 2024年第8期41卷 1696-1699页

作者：赵东兴杨永智陈林杨李春毕光林张建春李万云李永慧云南省红河热带农业科学研究所云南河口661399

云青1号是云南省红河热带农业科学研究所科研人员从云南省河口县集市上购买柚果后通过种子繁育选育出的柚新品种。该品种树势强旺,树姿开张,萌芽力中等,成枝能力强;果实呈饱满长水滴形,平均单果质量1.56 kg,果实可食率68%,可溶性固形物... 详细信息

云青1号是云南省红河热带农业科学研究所科研人员从云南省河口县集市上购买柚果后通过种子繁育选育出的柚新品种。该品种树势强旺,树姿开张,萌芽力中等,成枝能力强;果实呈饱满长水滴形,平均单果质量1.56 kg,果实可食率68%,可溶性固形物含量(w,后同)11.3%,总酸含量0.47 g·100 g^(-1),固酸比24.04,维生素C含量56.7 mg·100 g^(-1),维生素E含量0.407 mg·100 g^(-1)。在云南省河口县2月初现蕾,3月盛花,9月下旬成熟,果实生育期190 d左右。果实成熟后,果面主色绿色,果肉红色,汁胞呈水晶切面晶莹剔透,无苦麻味,汁胞不粒化,单一品种种植表现为无籽或少籽。该品种植株较耐贫瘠,耐高温高湿,适宜热区栽培,云南南部热区和全省低热河谷区域均可种植。

关键词：青皮红心柚新品种云青1号

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Themis suppresses the effector function of CD8^(+)T cells in acute viral infection

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Cellular & Molecular Immunology 2023年第5期20卷 512-524页

作者： Jian Tang Xian Jia Jian li Junchen Dong Jiayu Wang wanyun li Yuzhen Zhu Yanyan Hu Bowen Hou Chunjie lin Yu Cong Tong Ren Changsheng Yan Hongying Yang Qian Lai Haiping Zheng Yuzhou Bao Namrata Gautam Hong-Rui Wang Bing Xu Xiao Lei Chen Qing li Nicholas R.J.Gascoigne Guo Fu State Key Laboratory of Cellular Stress Biology School of MedicineFaculty of Medicine and Life SciencesXiamen UniversityXiamenChina School of life Sciences Xiamen UniversityXiamenChina Immunology Translational Research Programme Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Department of Microbiology and Immunology Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Department of Hematology The First Affiliated Hospital and Institute of HematologySchool of MedicineXiamen UniversityXiamenChina Cancer Research Center of Xiamen University XiamenChina

CD8^(+)T cells play a central role in antiviral immune *** infection,naive CD8^(+)T cells differentiate into effector cells to eliminate virus-infected cells,and some of these effector cells further differentiate into memory cells to provide long-term protection after infection is *** extensively investigated,the underlying mechanisms of CD+T-cell differentiation remain incompletely *** is a T-cell-specific protein that plays critical roles in T-cell *** studies using Themis T-cell conditional knockout mice also demonstrated that Themis is required to promote mature CD8^(+)T-cell homeostasis,cytokine responsiveness,and antibacterial *** this study,we used LCMV Armstrong infection as a probe to explore the role of Themis in viral *** found that preexisting CD8^(+)T-cell homeostasis defects and cytokine hyporesponsiveness do not impair viral clearance in Themis T-cell conditional knockout *** analyses showed that in the primary immune response,Themis deficiency promoted the differentiation of CD8^(+)effector cells and increased their TNF and IFNy ***,Themis deficiency impaired memory precursor cell(MPEC)differentiation but promoted short-lived effector cell(SLEC)*** deficiency also enhanced effector cytokine production in memory CD8^(+)T cells while impairing central memory CD8^(+)T-cell ***,we found that Themis mediates PD-1 expression and its signaling in effector CD8^(+)T cells,which explains the elevated cytokine production in these cells when Themis is disrupted.

关键词： Themis Effector T cell CD8 T-cell differentiation Cytokine LCMV

The synergy of dark septate endophytes and organic residue on Isatis indigotica growth and active ingredients accumulation under drought stress

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The synergy of dark septate endophytes and organic residue o...

The degradation ability of dark septate endophytes on lignocellulose affect its promotion effect on Isatis indigotica and improve the availability of organic additives by mobilizing soil carbon source cycle

中国菌物学会2023年学术年会

作者： wanyun li Jiaojie Yao Chao He Yanfng Ren lili Zhao Xueli He School of life Sciences Hebei University Institute of Medicinal Plant Development Chinese Academy of Medical Sciences & Peking Union Medical College

Drought is a major abiotic stress factor affecting plant growth and production,while utilizing beneficial endophytic fungi is one of the most promising strategies for enhancing plant growth and drought *** the present study,a pot experiment was conducted to investigate the beneficial effects of dark septate endophytes(DSE)(Acrocalymma aquatica and Alternaria alstroemeriae) combine with organic residues from sterilized or non-sterilized fermented corn straw by Trichoderma afroharzianum on the growth and drought resistance of Isatis *** stress(30% field water capacity) reduced the shoot biomass,root biomass,and epigoitrin content of *** by 34.30%,80.85%,and 16.51%,*** DSE inoculation alone increased shoot biomass and epigoitrin content under well-watered condition(70% field water capacity) by 13.75%-65.98% and 52.33%-67.59%,respectively,and shoot biomass under drought stress by 37.27%-84.91%.The organic residues application alone increased root biomass under well-watered condition and drought stress by 71.88%-107.06% and463.61%-678.69%,*** mixed application of DSE and organic residues increased root biomass and epigoitrin content under well-watered condition by 66.79%-144.66% and 89.02%-136.63%,respectively,and under drought stress by 410.66%-580.49% and 28.26%-88.37%,*** equation modeling demonstrated that DSE inoculation,organic residue application,and the mixed application improved the growth of *** under drought stress through different direct and indirect *** partitioning showed that DSE was the primary factor improving the epigoitrin content,and organic residue was the primary factor influencing plant biomass and morphological *** mixed application of DSE and organic residue had further synergistic effects on soil enzyme activities,soil organic matter,root biomass,and epigoitrin content,especially the mixed application of *** and sterilized or

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The degradation ability of dark septate endophytes on lignoc...

Maternal dietary patterns associated with bone density in Chinese lactating women and infants at 6 months postpartum:a prospective study using data from 2018-2019

中国菌物学会2023年学术年会

作者： wanyun li Chao He Minghui Xu Wanyi Zhang Menghui Wang lili Zhao Xueli He School of life Sciences Hebei University Institute of Medicinal Plant Development Chinese Academy of Medical Sciences & Peking Union Medical College

Dark septate endophytes(DSE) is a class of rhizosphere endophytic fungi that can form good interactions with host plants,but the understanding of its ecological functions is still limited,and there is a lack of direct evidence whether DSE can participate in the carbon cycle of *** this study,we aimed to reveal the relationship between the saprophytic interpretation potential and the bio promotive effect of DSE by taking the lignocellulosic degradation capacity of DSE as an entry point and to screen for multi-functional *** address this question,44 strains of DSE isolated from two ecological environments and 12 host plants were evaluated for their lignocellulosic component degradation potential by screening ***,the pot experiment and solid state fermentation were used to screen the dual-function DSE strains with promoting benefit and lignocellulose degradation ability,and to further explore the promoting value of DSE for Isatis indigotica growth under soil *** all the tested strains,42 strains had cellulose degradation capacity,40 strains had hemicellulose degradation capacity,42 strains had pectin degradation capacity,and 4 strains had lignin degradation *** genus specificity of DSE was the main factor affecting the degradation ability of DSE on *** single factor sterile pot experiment proved that degradation ability of DSE on lignocellulose could affect its colonization and growth promotion efficiency on *** selaginellae and Paraphoma chlamydocopiosa could produce high cellulase activity using untreated corn straw and licorice residues as fermentation substrates in solid state *** addition,the two strains could improve the utilization efficiency of organic residue to promote the growth of *** by mobilizing soil carbon source cycle.

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Food Science and Human Wellness 2024年第5期13卷 2668-2676页

作者： Yalin Zhou Xiaoyu Zhu Ying Lü Runlong Zhao Hanxu Shi wanyun Ye Zhang Wen Rui li Hanming Huang Yajun Xu Department of Nutrition and Food Hygiene School of Public HealthPeking UniversityBeijing100083China PKUHSC-China Feihe Joint Research Institute of Nutrition and Healthy lifespan Development Beijing 100083China Beijing Northern Hospital Beijing 100089China Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety Peking UniversityBeijing 100083China

This cohort study was designed to explore the relationship between maternal dietary patterns(DPs)and bone health in Chinese lactating mothers and *** recruited 150 lactating women at 1-month *** estimated bone mineral density(eBMD)of subjects’calcanei and the information on dietary intake were *** 5-month follow-up,the eBMD of mothers and their infants were measured *** analysis was applied to determine maternal *** linear models were used to evaluate the association between maternal DPs and maternal eBMD loss or infants’*** all potential covariates adjusted,Factor 2(high intake of whole grains,tubers,mixed beans,soybeans and soybean products,seaweeds,and nuts)showed a positive association with the changes of maternal eBMD(β=0.16,95%CI:0.005,0.310).Factor 3(high intake of soft drinks,fried foods,and puffed foods)was inversely correlated with the changes of maternal eBMD(β=-0.22,95%CI:-0.44,0.00).The changes of maternal eBMD were positively associated with 6-month infants’eBMD(β=0.34,95%CI:0.017,0.652).In conclusion,Factor 2 might contribute to the maintenance of eBMD in lactating women,while Factor 3 could exacerbate maternal eBMD ***,the changes of maternal eBMD presented a positive correlation with 6-month infants’eBMD.

关键词： Dietary patterns Estimated bone mineral density Lactating women

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共建命题信息库,让哲学教学进入快进模式

科教文汇 2016年第18期 133-134页

作者：李婉云广东省佛山市南海区罗村街道罗村高级中学广东佛山528226

在教学中,师生共建命题信息库,能让哲学教学进入快进模式,有效破解教学中学生听课一知半解、做题一塌糊涂、教学进度一拖再拖的问题。

关键词：命题信息哲学教学生活与哲学

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高校民族团结教育实践研究回顾与展望

新疆广播电视大学学报 2019年第3期23卷 18-22页

作者：李宛芸李乐新疆大学马克思主义学院

国内学界对高校民族团结教育实践研究成果颇丰,但存在对民族团结教育实效性研究欠缺以及研究的学科视角较窄等问题。本文对近20年的高校民族团结教育进步实效性研究、内涵式发展研究,以推动全媒体时代高校民族团结教育的深入研究。

关键词：民族团结教育高校

髓样细胞触发受体-1与肝细胞癌发生和发展的相关性

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南方医科大学学报 2015年第12期35卷 1705-1709,1720页

作者：李皖云张娜欧玉荣周争光赵福友吴穷杨燕蚌埠医学院第一附属医院病理科安徽蚌埠233004 蚌埠医学院第一附属医院肿瘤内科安徽蚌埠233004

目的研究髓样细胞触发受体-1(TREM-1)在人肝细胞癌(HCC)发生发展过程中的表达及意义。方法应用免疫组化法检测HCC 76例、肝硬化33例、肝炎30例、正常肝组织20例中TREM-1蛋白的表达及定位,并对该蛋白与HCC临床病理特征之间的关系进行分... 详细信息

目的研究髓样细胞触发受体-1(TREM-1)在人肝细胞癌(HCC)发生发展过程中的表达及意义。方法应用免疫组化法检测HCC 76例、肝硬化33例、肝炎30例、正常肝组织20例中TREM-1蛋白的表达及定位,并对该蛋白与HCC临床病理特征之间的关系进行分析。进一步在体外使用人正常肝细胞LO2和肝癌细胞SMMC-7721,采用RT-PCR和Western blotting法检测TREM-1 m RNA及蛋白表达,以证实组织学结果。结果正常肝组织中TREM-1为阴性表达;肝炎、肝硬化和HCC组织中该蛋白表达显著上调,阳性表达率分别为20.00%(6/30)、24.24%(8/33)和21.05%(16/76),但该3组间差异无统计学意义(χ2=0.195,P=0.907)。与非癌肝组织(肝炎、肝硬化组织)相比,HCC组织中阳性表达的TREM-1蛋白定位发生明显改变:非癌肝组织中TREM-1主要定位于肝细胞胞核中,偶见定位于细胞质;HCC组织中阳性表达的蛋白颗粒均位于癌细胞胞质,未见细胞核定位。TREM-1蛋白与癌病理分级呈负相关(r=-0.261,P=0.023),而与年龄、性别、肿瘤大小、临床分期、肝病背景、淋巴结转移及脉管癌栓无明显相关(均P>0.05)。细胞学实验显示LO2细胞有部分TREM-1 m RNA及蛋白表达,而SMMC-7721肝癌细胞该指标明显上调。结论 TREM-1蛋白的表达上调及在胞质中的异常定位可能与HCC发生发展相关。

关键词：肝细胞癌髓样细胞触发受体-1 炎症因子免疫组化异常定位