检索结果-南通市图书馆

Communications in Theoretical Physics 2006年第2X期46卷 313-318页

作者： wang yue-yue ZHANG Jie-Fang Institute of Nonlinear Physics Zhejiang Normal University Jinhua 321004 China

In this paper, the cylindrical KP-Burgers equation with variable coefficient for two-temperature ions in unrsagnified dusty plasma with dissipative effects and transverse perturbations in cylindrical geometry is derived by using the standard reductive perturbation technique. With the help of variable-coeiffcient generalized projected Ricatti equation expansion method, the cylindrical KP-Burgers equation is solved and shock wave solution is obtained. The effecta of some important parameters to the shock wave solution are illustrated from the wave evolution figures. The effects caused by dissipation and transverse perturbations are also discussed.

关键词： dusty plasma KP-Burgers equation shock wave

Solitary Wave Solutions of Discrete Complex Ginzburg-Landau Equation by Modified Adomian Decomposition Method

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2009年第1期51卷 81-89页

作者： wang yue-yue DAI Chao-Qing ZHANG Jie-Fang Department of Sciences Zhejiang Forestry University Zhejiang Lin＇an 311300 China Institute of Nonlinear Physics Zhejiang Normal University Jinhua 321004 China

In this paper, exact and numerical solutions are calculated for discrete complex Ginzburg-Landau equation with initial condition by considering the modified Adomian decomposition method （mADM）, which is an efficient method and does not need linearization, weak nonlinearity assumptions or perturbation theory. The numerical solutions are also compared with their corresponding analytical solutions. It is shown that a very good approximation is achieved with the analytical solutions. Finally, the modulational instability is investigated and the corresponding condition is given.

关键词： discrete complex Ginzburg-Landau equation modified Adomian decomposition method solitary wave solutions modulational instability

Inhibition of the cGAS–STING pathway:contributing to the treatment of cerebral ischemia-reperfusion injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第7期20卷 1900-1918页

作者： Hang Yang Yulei Xia yue Ma Mingtong Gao Shuai Hou Shanshan Xu Yanqiang wang School of Clinical Medicine Shandong Second Medical UniversityWeifangShandong ProvinceChina Department of Emergency The Affiliated Hospital of Weifang Medical UniversityWeifangShandong ProvinceChina Department of Neurology Ⅱ The Affiliated Hospital of Weifang Medical UniversityWeifangShandong ProvinceChina

The cGAS–STING pathway plays an important role in ischemia-reperfusion injury in the heart,liver,brain,and kidney,but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically ***,we outline the components of the cGAS–STING pathway and then analyze its role in autophagy,ferroptosis,cellular pyroptosis,disequilibrium of calcium homeostasis,inflammatory responses,disruption of the blood–brain barrier,microglia transformation,and complement system activation following cerebral ischemia-reperfusion *** further analyze the value of cGAS–STING pathway inhibitors in the treatment of cerebral ischemia-reperfusion injury and conclude that the pathway can regulate cerebral ischemia-reperfusion injury through multiple *** of the cGAS–STING pathway may be helpful in the treatment of cerebral ischemia-reperfusion injury.

关键词： calcium homeostasis cellular autophagy cerebral ischemia-reperfusion injury cGAS–STING pathway ferroptosis gut–brain–microbiota axis inflammatory light chain 3 microglial cells Syntaxin-17 protein

Hypidone hydrochloride(YL-0919)ameliorates functional deficits after traumatic brain injury in mice by activating the sigma-1 receptor for antioxidation

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2325-2336页

作者： Yafan Bai Hui Ma yue Zhang Jinfeng Li Xiaojuan Hou Yixin Yang Guyan wang Yunfeng Li Department of Anesthesiology Beijing Tongren HospitalCapital Medical UniversityBeijingChina Beijing Institute of Basic Medical Sciences BeijingChina Hebei North University ZhangjiakouHebei ProvinceChina Beijing Institute of Pharmacology and Toxicology State Key Laboratory of Toxicology and Medical CountermeasuresBeijing Key Laboratory of NeuropsychopharmacologyBeijingChina

Traumatic brain injury involves complex pathophysiological mechanisms,among which oxidative stress significantly contributes to the occurrence of secondary *** this study,we evaluated hypidone hydrochloride(YL-0919),a self-developed antidepressant with selective sigma-1 receptor agonist properties,and its associated mechanisms and targets in traumatic brain *** experiments to assess functional deficits were followed by assessment of neuronal damage through histological analyses and examination of blood-brain barrier permeability and brain ***,we investigated the antioxidative effects of YL-0919 by assessing the levels of traditional markers of oxidative stress in vivo in mice and in vitro in HT22 ***,the targeted action of YL-0919 was verified by employing a sigma-1 receptor antagonist(BD-1047).Our findings demonstrated that YL-0919 markedly improved deficits in motor function and spatial cognition on day 3 post traumatic brain injury,while also decreasing neuronal mortality and reversing blood-brain barrier disruption and brain ***,YL-0919 effectively combated oxidative stress both in vivo and in *** protective effects of YL-0919 were partially inhibited by *** results indicated that YL-0919 relieved impairments in motor and spatial cognition by restraining oxidative stress,a neuroprotective effect that was partially reversed by the sigma-1 receptor antagonist ***-0919 may have potential as a new treatment for traumatic brain injury.

关键词： antidepressant drug blood-brain barrier cognitive function hypidone hydrochloride(YL-0919) neurological function nuclear factor-erythroid 2 related factor 2 oxidative stress sigma-1 receptor superoxide dismutase traumatic brain injury

Microglia lactylation in relation to central nervous system diseases

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 29-40页

作者： Hui Yang Nan Mo Le Tong Jianhong Dong Ziwei Fan Mengxian Jia Juanqing yue Ying wang School of Pharmacy Hangzhou Normal UniversityHangzhouZhejiang ProvinceChina Department of Clinical Laboratory The Fourth Clinical Medical College of Zhejiang University of Traditional Chinese Medicine(Hangzhou First People’s Hospital)HangzhouZhejiang ProvinceChina College of Medical Veterinary and Life SciencesUniversity of GlasgowGlasgowUK Department of Orthopedics(Spine Surgery) the First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina Department of Pathology Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang ProvinceChina Department of Clinical Research Center Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang ProvinceChina

The development of neurodegenerative diseases is closely related to the disruption of central nervous system ***,as innate immune cells,play important roles in the maintenance of central nervous system homeostasis,injury response,and neurodegenerative *** has been considered a metabolic waste product,but recent studies are revealing ever more of the physiological functions of *** is an important pathway in lactate function and is involved in glycolysis-related functions,macrophage polarization,neuromodulation,and angiogenesis and has also been implicated in the development of various *** review provides an overview of the lactate metabolic and homeostatic regulatory processes involved in microglia lactylation,histone versus non-histone lactylation,and therapeutic approaches targeting ***,we summarize the current research on microglia lactylation in central nervous system diseases.A deeper understanding of the metabolic regulatory mechanisms of microglia lactylation will provide more options for the treatment of central nervous system diseases.

关键词： brain central nervous system glycolysis immune response inflammation lactate metabolism lactate lactylation microglia neurodegenerative diseases

在线全文

学校读者我要写书评

暂无评论

银中杨各部位对Cd、Zn、Pb的富集特性

北京林业大学学报 2018年第1期40卷 83-88页

作者：姜礅王月月严善春东北林业大学林学院黑龙江哈尔滨150040

【目的】为探明银中杨各部位对不同重金属的富集特性。【方法】本研究通过用3种不同含量的镉(Cd,0.5、1.5、2.5 mg/kg)、锌(Zn,300、500、700 mg/kg)或铅(Pb,300、500、700 mg/kg)分别处理盆栽一年生银中杨的土壤,分析银中杨根、茎、叶... 详细信息

【目的】为探明银中杨各部位对不同重金属的富集特性。【方法】本研究通过用3种不同含量的镉(Cd,0.5、1.5、2.5 mg/kg)、锌(Zn,300、500、700 mg/kg)或铅(Pb,300、500、700 mg/kg)分别处理盆栽一年生银中杨的土壤,分析银中杨根、茎、叶对Cd、Zn和Pb的富集量和富集系数。【结果】银中杨根、茎、叶对Cd、Zn和Pb的富集量均与土壤中相应的重金属含量呈极显著的正相关(P根>茎,在中、高含量时表现为根>叶>茎;对Pb的富集主要集中在根。

关键词：重金属银中杨富集量富集系数

从遗产到资源:传统手工艺类非遗的乡村角色研究--以贵州省为例

在线全文

学校读者我要写书评

暂无评论

东南文化 2022年第5期 19-25页

作者：王月月段勇山东工艺美术学院艺术人类学研究所山东济南250300 上海大学文学院上海200444

传统手工艺类非物质文化遗产产生于特定的历史时期,是动静结合的历史记忆者,其历时性、载体性、传承性体现了遗产角色。传统手工艺类非物质文化遗产作为重要的文化资源类别,各方主体在助其由资源转化为经济效益的进程中存在传承地文化... 详细信息

传统手工艺类非物质文化遗产产生于特定的历史时期,是动静结合的历史记忆者,其历时性、载体性、传承性体现了遗产角色。传统手工艺类非物质文化遗产作为重要的文化资源类别,各方主体在助其由资源转化为经济效益的进程中存在传承地文化生态衰微、产品同质化严重、产品供需矛盾、缺乏优势品牌等问题。基于遗产保存与资源利用的视角,保护主体应着力保护传统手工艺赖以生存的传统村落生态、助力后继人才的培育,传承主体应在坚守核心技艺的基础上适度创新,利用主体在尊重传统手工艺文化的基础上创新设计与生产,共同助力传统手工艺在乡村振兴中形成持久的内生性造血机制。

关键词：传统手工艺非物质文化遗产文化资源文化经济保护传承保护性利用乡村振兴

在线全文

学校读者我要写书评

暂无评论

基于个体出行数据的公共交通出行链提取方法

交通运输系统工程与信息 2017年第3期17卷 67-73页

作者：翁剑成王昌王月玥陈智宏彭曙北京工业大学交通工程北京市重点实验室北京100124 北京市轨道交通指挥中心北京100101 交通运输部路网监测与应急处置中心北京100088 井冈山大学机电工程学院江西吉安343009

公共交通个体出行信息的提取对掌握公共交通出行的时空特征,改善居民通勤出行效率具有重要意义.研究从公交刷卡数据、公交定位数据、轨道AFC数据等海量公共交通多源数据的关联匹配与处理方法入手,提出了公共交通出行链信息提取中,换乘... 详细信息

公共交通个体出行信息的提取对掌握公共交通出行的时空特征,改善居民通勤出行效率具有重要意义.研究从公交刷卡数据、公交定位数据、轨道AFC数据等海量公共交通多源数据的关联匹配与处理方法入手,提出了公共交通出行链信息提取中,换乘关系判断、通勤行为判别及出行起讫点匹配的方法与规则,标定了出行链匹配阈值参数,建立了基于个体出行数据的公共交通通勤出行链提取模型.提取模型的准确度验证表明:出行链结构提取及通勤出行判别的成功率均达到100%,出行阶段起讫点匹配成功率为87.5%,准确性为97.1%,满足了公共交通出行特征提取的需求.该方法为公共交通通勤出行判别及基于个体的微观通勤出行时空特征的深入分析奠定了基础.

关键词：城市交通出行链公交多源数据通勤出行个体出行感知出行特征

RCEP与CPTPP鼓励性知识产权条款与中国因应

在线全文

学校读者我要写书评

暂无评论

云南社会科学 2022年第4期 142-153页

作者：马忠法王悦玥复旦大学法学院

在多边或双边经济贸易协议等条约中,鼓励性条款作为条约的重要组成部分,与约束性条款一起构成完整的条约内容,日渐成为一种趋势。虽然不具有强制性,但是鼓励性条款在很大程度上反映了各成员所期望追求但暂时没有能力实现的目标。一些RCE... 详细信息

在多边或双边经济贸易协议等条约中,鼓励性条款作为条约的重要组成部分,与约束性条款一起构成完整的条约内容,日渐成为一种趋势。虽然不具有强制性,但是鼓励性条款在很大程度上反映了各成员所期望追求但暂时没有能力实现的目标。一些RCEP中的鼓励性条款在CPTPP、《中美经济贸易协议》中均具有约束性。RCEP、CPTPP中的鼓励性条款的出现,说明国际知识产权规则的保护范围逐渐扩大,发达国家在知识产权全球治理上的垄断话语逐步被打破,知识产权合作受到更多的关注且合作范围更加广泛以及发展中国家关注的议题逐步被重视。《中美经济贸易协议》如果与RCEP、CPTPP的鼓励性条款进行比较,可以发现该双边条约给中国施加的义务过重,有违利益平衡原则。中国应当以RCEP鼓励性条款的落实衔接CPTPP的加入,以鼓励性条款的落实彰显知识产权全球治理中的大国形象,以多边条约的鼓励性条款作为双边谈判底线,谨防发达国家利用其优势地位在双边条约中不当输出其国内制度带来不公平结果。

关键词： RCEP CPTPP 鼓励性条款中美第一阶段经贸协议

同方期刊数据库

THE ROLE OF INSULIN MEDIATORS IN REGULATION OF cAMP AND LIPOGENESIS AS WELL AS IN DIABETES

在线全文

学校读者我要写书评

暂无评论

Science in China,Ser.B 1987年第8期30卷 832-841页

作者：张世荣魏铁拳姚文贞韩锦华幸兴球王越王敬泽乐云 Department of Endocrinology Institute of Zoology Academia Sinica Beijing

Plasma membranes prepared from pig, mouse and rat liver incubated with insulin resulted in the release of at least two insulin chemical mediators. These mediators, identified as fractions 1 and 3, were found to inhibit cAMP level in response to lipolytic hormone and forskolin and to enhance lipogenesis in adipocytes of rat. Fractions 1 and 3 have been estimated to have molecular weights of 3700—4000 and 1000—1500 dalton, respectively. This initial report will focus on fraction ***, liver membranes from diabetic animals were found not to release mediators in the presence of insulin. However, following in vivo treatment of diabetic animals with insulin, the liver membranes appeared to restore its ability in generating chemical mediators in response to insulin.

关键词： THE ROLE OF INSULIN MEDIATORS IN REGULATION OF cAMP AND LIPOGENESIS AS WELL AS IN DIABETES AS