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中国造纸 2008年第12期27卷 43-45页

作者：冀亚超王海毅王志杰王永伟陕西科技大学造纸工程学院陕西西安710021 奥伯尼工程纺织品杭州有限公司浙江萧山311231

利用NDC在线检测仪检验成形网各部分的脱水性能,分析各部分脱水变化的原因,为纸张的优质生产服务。

关键词：成形网 NDC 脱水性能湿部

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电泳法鉴定脱墨浆生产系统过氧化氢酶

中华纸业 2008年第6期29卷 22-26页

作者：刘蓓王海毅陕西科技大学西安710021

研究聚丙烯酰胺凝胶电泳(polyacrylamide gel electrophoresis,简称PAGE)鉴定脱墨浆(DIP)生产系统中过氧化氢酶的实验条件,并对各工段过氧化氢酶同工酶进行分析。实验结果表明,碎浆工段点样量3μL,一段浓缩点样量5μL,二段浓缩点样量10... 详细信息

研究聚丙烯酰胺凝胶电泳(polyacrylamide gel electrophoresis,简称PAGE)鉴定脱墨浆(DIP)生产系统中过氧化氢酶的实验条件,并对各工段过氧化氢酶同工酶进行分析。实验结果表明,碎浆工段点样量3μL,一段浓缩点样量5μL,二段浓缩点样量10μL,浓缩胶质量分数4%,分离胶质量分数9%,才能得到较高质量的电泳结果。生产系统中共检测出6条酶带,各工段出现的酶带的数量不同,种类也不同,仅有一条酶带在三个工段均出现,探讨了此现象产生的原因并对6种同工酶分子量进行排序。

关键词：过氧化氢酶电泳同工酶

西门子PCS7在高速包装纸机生产控制中的应用

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中华纸业 2010年第12期31卷 74-76页

作者：谈建新王益海四川高达科技有限公司四川绵阳621000

在高速包装纸机中,传动控制系统的装机容量大、数量多,与DCS、MCS等系统之间的联锁比较复杂,控制量也比较大,因此选择合适的控制系统是决定纸机能否正常稳定运行的关键。本文介绍了采用西门子PCS7系统解决高速包装纸机全线控制的任务,... 详细信息

在高速包装纸机中,传动控制系统的装机容量大、数量多,与DCS、MCS等系统之间的联锁比较复杂,控制量也比较大,因此选择合适的控制系统是决定纸机能否正常稳定运行的关键。本文介绍了采用西门子PCS7系统解决高速包装纸机全线控制的任务,为类似工程项目的建设提供了很好的借鉴。

关键词：高速包装纸机 PCS7 全集成

Layered oxide cathodes for sodium-ion batteries:microstructure design,local chemistry and structural unit

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Science China Chemistry 2024年第1期67卷 191-213页

作者： Ling-yi Kong Han-Xiao Liu Yan-Fang Zhu Jia-Yang Li Yu Su Hong-Wei Li hai-Yan Hu yi-Feng Liu Ming-Jing Yang Zhuang-Chun Jian Xin-Bei Jia Shu-Lei Chou Yao Xiao Institute for Carbon Neutralization College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325035China

Because of the low price and abundant reserves of sodium compared with lithium,the research of sodium-ion batteries(SIBs)in the field of large-scale energy storage has returned to the research *** oxides distinguish themselves from the mains cathode materials of SIBs owing to their advantages such as high specific capacity,simple synthesis route,and environmental ***,the commercial development of the layered oxides is limited by sluggish kinetics,complex phase transition and poor air *** on the research ideas from macro-to micro-scale,this review systematically summarizes the current optimization strategies of sodium-ion layered oxide cathodes(SLOC)from different dimensions:microstructure design,local chemistry regulation and structural unit *** the dimension of microstructure design,the various structures such as the microspheres,nanoplates,nanowires and exposed active facets are prepared to improve the slow kinetics and electrochemical ***,from the view of local chemistry regulation by chemical element substitution,the intrinsic electron/ion properties of SLOC have been enhanced to strengthen the structural ***,the optimization idea of endeavors to regulate the physical and chemical properties of cathode materials essentially is put forward from the dimension of structural unit *** opinions and strategies proposed in this review will provide some inspirations for the design of new SLOC in the future.

关键词： sodium-ion batteries layered oxide cathodes microstructure design local chemistry structural unit

Nanocavity enriched CuPd alloy with high selectivity for CO_(2) electroreduction toward C_(2)H_(4)

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Rare Metals 2024年第4期43卷 1513-1523页

作者： Ze-Yu Zhang hai-Bin wang Fei-Fei Zhang Jing-Wei Li Xin-Zhuo Hu Si-Wei Yan yi-Ming Bai Xun Zhang Gu-Rong Shen Peng-Fei yin Jing Yang Cun-Ku Dong Jing Mao Hui Liu Xi-Wen Du Institute of New-Energy Materials School of Materials Science and EngineeringTianjin UniversityTianjin300350China

Electrocatalysis of CO_(2)reduction reaction is an effective way to convert CO_(2)into high value-added products,but the selectivity of Cu-based catalysts for C2+products needs to be improved due to the high energy barrier of C-C ***,a viable catalyst design strategy to decrease energy barrier of C-C coupling should be put ***,a nanocavity-enriched CuPd single atom alloy(CuPd SAA)catalyst is designed to promote CC coupling *** faradaic efficiency of CuPd SAA for ethylene and C_(2+)reaches 75.6%and 85.7%at-0.7 V versus reversible hydrogen electrode(RHE),*** on the results given by in situ characterization,the porous hollow structure dramatically increases the ratio of the linear-bond*CO,thus enhancing the faradaic efficiency for *** functional theory(DFT)calculation reveals that the Pd doping can regulate the electronic structure of neighboring Cu atoms to decrease the energy barrier of C-C coupling,further improving the faradaic *** work provides a new idea for designing catalyst with high selectivity for ethylene.

关键词： Adsorption configuration C-C coupling CO_(2) electrocatalysis Ethylene Single atom alloy

Babao Dan Inhibits Gastric Cancer Progression in vivo Through Multiple Signaling Pathways

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World Journal of Traditional Chinese Medicine 2024年第1期10卷 14-21页

作者： hai-Xia Shang yi Fang Bin Guan Jian-Hua Guan Jun Peng Jin-Yan Zhao Jiu-Mao Lin Institute of Oncology of Academy of Integrative Medicine Fujian University of Traditional Chinese MedicineFuzhouFujianChina Key Laboratory of Integrative Medicine of Fujian Province University Fujian University of Traditional Chinese MedicineFuzhouFujianChina Fujian Key Laboratory of Integrative Medicine on Geriatric Fujian University of Traditional Chinese MedicineFuzhouFujianChina Innovation and Transformation Center Fujian University of Traditional Chinese MedicineFuzhouFujianChina Xiamen Traditional Chinese Medicine Co. Ltd.XiamenFujianChina

Objective:The aim of this study was to explore the effects of Babao dan(BBD),a traditional Chinese medicine,on gastric cancer(GC)progression in *** and Methods:A subcutaneous xenograft mouse model of GC was established using MGC80-3 *** terminal deoxynucleotidyl transferase-mediated dUTP:2'-deoxyuridine 5'-triphosphate-biotin nick-end labeling method was adopted to detect cell apoptosis in *** expression levels of proteins associated with proliferation,apoptosis,and angiogenesis were measured by immunohistochemical staining or western blotting(WB).The activation and protein levels of p-c-Jun N-terminal kinase(JNK),p-p38,p-extracellular-regulated kinase 1/2,p-nuclear factor-κB(NF-κB),and p-STAT3 were examined by Bio-plex and ***:BBD significantly inhibited tumor growth in GC mouse models with no adverse effect on body weight or organ *** was also found that BBD significantly suppressed the proliferation of GC tumor cells,induced the apoptosis of tumor cells,and inhibited angiogenesis through inactivating with mitogen-activated protein kinase,NF-κB,and STAT3 ***:BBD exerts suppressive effects on GC tumor growth by regulating multiple pathways in vivo,which may provide a novel treatment option for GC therapy.

关键词： Babao dan gastric cancer multiple signaling pathways proliferation traditional Chinese medicine

Drug delivery with Mn-doped MoO_(2) for photothermalenhanced chemotherapy in fighting cancers

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Rare Metals 2024年第5期43卷 2230-2240页

作者： Ping Zhao hai-Fa Zheng Ju Peng Xing-Long Li Fazal Raziq Xiao-Jun Liu Hao-Quan Yu Jin-Lu Tang yi-Fan Kang Wen-Huan Huang School of Chemistry and Chemical Engineering Guangdong Pharmaceutical UniversityGuangzhou 510006China KAUST Catalysis Center King Abdullah University of Science and Technology23955-6900 ThuwalKingdom of Saudi Arabia Key Laboratory of Chemical Additives for China National Light Industry College of Chemistry and Chemical EngineeringShaanxi University of Science and TechnologyXi'an 710021China

Although chemotherapy has been intensively applied in cancer treatments,its inadequate therapeutic efficacy and severe side effects are still under constant *** used as anti-tumor drug delivery system(DDS)have attracted tremendous attentions owing to their various intriguing ***,Mn-doped MoO_(2)nanoparticles coated with ZrO_(2)and capped with Bi_(2)O_(3)have been designed as a DDS,namely *** possesses good magnetic properties,great photothermal conversion ability,sensitive tumor microenvironment(TME)responsiveness,and good biocompatibility in hemocompatibility in ***,MMZB has been utilized to load the chemotherapeutic agent daunomycin(DNM)(MMZB@DNM)for chemo-photothermal combined ***@DNM demonstrates a more impressive anti-cancer effect than the individual photothermal or chemotherapy both in vitro and in ***,the analysis of tumor specimen sections and serum levels after the treatment indicates negligible side effects for MMZB@DNM in *** contribution provides a valuable concept in designing therapeutic agents for achieving significantly enhanced tumor treatments,which benefits from the synergistic combination of chemotherapy and photothermal therapy in one single nanoagent.

关键词： Mn-doped MoO_(2) Bi_(2)O_(3) Nanocarrier Photothermal Chemotherapy

Application of deep learning methods combined with physical background in wide field of view imaging atmospheric Cherenkov telescopes

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Nuclear Science and Techniques 2024年第4期35卷 208-220页

作者： Ao-Yan Cheng Hao Cai Shi Chen Tian-Lu Chen Xiang Dong You-Liang Feng Qi Gao Quan-Bu Gou yi-Qing Guo Hong-Bo Hu Ming-Ming Kang hai-Jin Li Chen Liu Mao-Yuan Liu Wei Liu Fang-Sheng Min Chu-Cheng Pan Bing-Qiang Qiao Xiang-Li Qian Hui-ying Sun Yu-Chang Sun Ao-Bo wang Xu wang Zhen wang Guang-Guang Xin Yu-Hua Yao Qiang Yuan yi Zhang School of Physics and Technology Wuhan UniversityWuhan 430072China School of Physics and Astronomy Yunnan UniversityKunming 650091China Ministry of Education The Key Laboratory of Cosmic Rays(Tibet University)Lhasa 850000China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences 19 A Yuquan RoadShijingshan DistrictBeijing 100049China College of Physics Sichuan UniversityChengdu 610064China School of Intelligent Engineering Shandong Management UniversityJinan 250357China Tsung‑Dao Lee Institute Shanghai Jiao Tong UniversityShanghai 200240China Suzhou Aerospace Information Research Institute Suzhou 215123China College of Physics Chongqing UniversityNo.55 Daxuecheng South RoadHigh‑tech DistrictChongqing 401331China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210008China

The High Altitude Detection of Astronomical Radiation(HADAR)experiment,which was constructed in Tibet,China,combines the wide-angle advantages of traditional EAS array detectors with the high-sensitivity advantages of focused Cherenkov *** objective is to observe transient sources such as gamma-ray bursts and the counterparts of gravitational *** study aims to utilize the latest AI technology to enhance the sensitivity of HADAR *** datasets and models with distinctive creativity were constructed by incorporating the relevant physical theories for various *** models can determine the type,energy,and direction of the incident particles after careful *** obtained a background identification accuracy of 98.6%,a relative energy reconstruction error of 10.0%,and an angular resolution of 0.22°in a test dataset at 10 *** findings demonstrate the significant potential for enhancing the precision and dependability of detector data analysis in astrophysical *** using deep learning techniques,the HADAR experiment’s observational sensitivity to the Crab Nebula has surpassed that of MAGIC and *** energies below 0.5 TeV and remains competitive with conventional narrow-field Cherenkov telescopes at higher *** addition,our experiment offers a new approach for dealing with strongly connected,scattered data.

关键词： VHE gamma-ray astronomy HADAR Deep learning Convolutional neural networks

RARRES2 regulates lipid metabolic reprogramming to mediate the development of brain metastasis in triple negative breast cancer

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Military Medical Research 2024年第1期11卷 34-49页

作者： yi-Qun Li Fang-Zhou Sun Chun-Xiao Li Hong-Nan Mo Yan-Tong Zhou Dan Lv Jing-Tong Zhai hai-Li Qian Fei Ma Department of Medical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China State Key Laboratory of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

Background Triple negative breast cancer(TNBC),the most aggressive subtype of breast cancer,is characterized by a high incidence of brain metastasis(BrM)and a poor *** the most lethal form of breast cancer,BrM remains a major clinical challenge due to its rising incidence and lack of effective treatment *** evidence suggested a potential role of lipid metabolic reprogramming in breast cancer brain metastasis(BCBrM),but the underlying mechanisms are far from being fully *** Through analysis of BCBrM transcriptome data from mice and patients,and immunohistochemical validation on patient tissues,we identified and verified the specific down-regulation of retinoic acid receptor responder 2(RARRES2),a multifunctional adipokine and chemokine,in BrM of *** investigated the effect of aberrant RARRES2 expression of BrM in both in vitro and in vivo *** signaling pathway components were evaluated using multi-omics *** were performed to elucidate the regulation of lipid metabolic reprogramming of *** We found that downregulation of RARRES2 is specifically associated with BCBrM,and that RARRES2 deficiency promoted BCBrM through lipid metabolic ***,reduced expression of RARRES2 in brain metastatic potential TNBC cells resulted in increased levels of glycerophospholipid and decreased levels of triacylglycerols by regulating phosphatase and tensin homologue(PTEN)-mammalian target of rapamycin(mTOR)-sterol regulatory element-binding protein 1(SREBP1)signaling pathway to facilitate the survival of breast cancer cells in the unique brain *** Our work uncovers an essential role of RARRES2 in linking lipid metabolic reprogramming and the development of ***2-dependent metabolic functions may serve as potential biomarkers or therapeutic targets for BCBrM.

关键词： RARRES2 Lipid metabolic reprogramming Brain metastasis(BrM) Breast cancer

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细胞腔加填与细胞壁加填

纸和造纸 2006年第1期25卷 64-66页

作者：郝妮王海毅陕西科技大学造纸工程学院陕西省造纸技术及特种纸品开发重点实验室咸阳712081

介绍了细胞腔、细胞壁加填技术以及它们的研究与应用现状,并与传统直接加填的方式进行了比较,显示出细胞腔加填技术及细胞壁加填技术的优越性。

关键词：细胞腔加填细胞壁加填直接加填填料