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Development and validation of a new prognostic model for patients with acute-on-chronic liver failure in intensive care unit

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World Journal of Gastroenterology 2024年第20期30卷 2657-2676页

作者： Zong-yi Zhu Xiu-Hong huang Hui-Qing Jiang li liu Department of Gastroenterology The Second Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina Department of Gastroenterology Weixian People's HospitalXingtai 054700Hebei ProvinceChina

BACKGROUND Cirrhotic patients with acute-on-chronic liver failure(ACLF)in the intensive care unit(ICU)have a poor but variable *** prognosis evaluation can guide the rational management of patients with ***,existing prognostic scores for ACLF in the ICU environment lack sufficient *** To develop a new prognostic model for patients with ACLF in *** Data from 938 ACLF patients in the Medical Information Mart for Intensive Care(MIMIC)database were used to develop a new prognostic model(MIMIC ACLF)for ***,calibration and clinical utility of MIMIC ACLF were assessed by area under receiver operating characteristic curve(AUROC),calibration curve and decision curve analysis(DCA),*** ACLF was then externally validated in a multiple-center cohort,the Electronic Intensive Care Collaborative Research Database and a single-center cohort from the Second Hospital of Hebei Medical University in *** The MIMIC ACLF score was determined using nine variables:ln(age)×2.2+ln(white blood cell count)×0.22-ln(mean arterial pressure)×2.7+respiratory failure×0.6+renal failure×0.51+cerebral failure×0.31+ln(total bilirubin)×0.44+ln(internationalized normal ratio)×0.59+ln(serum potassium)×*** MIMIC cohort,the AUROC(0.81/0.79)for MIMIC ACLF for 28/90-day ACLF mortality were significantly greater than those of Chronic liver Failure Consortium ACLF(0.76/0.74),Model for End-stage liver Disease(MELD;0.73/0.71)and MELD-Na(0.72/0.70)(all Psistency between actual and predicted 28/90-day survival rates of patients according to MIMIC ACLF score was excellent and superior to that of existing *** net benefit of MIMIC ACLF was greater than that achieved using existing scores within the 50%threshold *** superior predictive accuracy and clinical utility of MIMIC ACLF were validated in the external *** We developed and validated a new prognostic model with satisfactory accuracy

关键词： Acute-on-chronic liver failure Cirrhosis Risk stratification Prognosis Model Scores

Age,Genesis,and Tectonic Setting of the Mo-W Mineralized Dongshanwan Granite Porphyry from the Xilamulun Metallogenic Belt,NE China

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Journal of Earth Science 2017年第3期28卷 433-446页

作者： Xuebing Zhang Keyong wang Chengyang wang Wen li Qi YU yicun wang Jianfeng li Duo Wan Guanghuan huang College of Earth Sciences Jilin UniversityChangchun 130061China Department of Earthquake Seienee Institute of Disaster Prevention Science and TechnologyBeijing 101601China Inner Mongolia Shandong Gold Minerals Survey Co.Ltd. Chifeng 024005China Heilongjiang Institute of Regional Geology Survey Harbin 150080China College of Urban and Environmental Sciences Liaoning Normal UniversityDalian 116029China

The Xilamulun molybdenum polymetallic metallogenic belt in eastern Inner Mongolia forms one of the most important Mo metallogenic belts in northeastern China. The Dongshanwan porphyry Mo-W polymetallic deposit, in the northeastern part of the Xilamulun metallogenic belt, occurs along the periphery of a granite porphyry and consists of Mo-W-Ag sulfide and oxide disseminations and veinlets in hydrothermal assemblages. LA-ICP-MS zircon U-Pb dating of the Dongshanwan granite porphyry yields a crystallization age of 142.15± 0.91 Ma, whereas molybdenite Re-Os isotopic dating model ages are of 139.9–141.5 Ma and an isochron age is of 140.5± 3.2 Ma（MSWD=1.2）. The age consistency indicates that the Dongshanwan deposit was a product of Early Cretaceous magmatism. The Dongshanwan granite porphyry is a high-alkali high-potassium intrusion and has high siO_2（75.39 wt.%–76.15 wt.%）, low Al_2O_3（12 wt.%–13 wt.%）, Ba, Ti, P, and Sr contents, with negative Eu anomalies. The Y/Nb ratios are comparable to those of average continental crust and island arc basalts, corresponding to type-A2 granites. Our geochemical data indicate that the granite porphyry emplaced in an Early Cretaceous post-orogenic extensional environment following Mongol-Okhotsk oceanic subduction and subsequent continental collision.

关键词： Dongshanwan porphyry Mo-W deposit zircon U-Pb dating Re-Os dating geochemistry Xilamulun metallogenic belt

Review of PPP-RTK:achievements,challenges,and opportunities

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Satellite Navigation 2022年第3期3卷 16-37,I0002页

作者： Xingxing li Jiaxin huang Xin li Zhiheng Shen Junjie Han linyang li Bo wang School of Geodesy and Geomatics Wuhan University129 Luoyu RoadWuhan430079HubeiChina Technische Universitat Berlin(TUB) Straße Des 17.Juni10623BerlinGermany China Railway siyuan Survey and Design Group Co. Ltd.WuhanChina

The PPP–RTK method,which combines the concepts of Precise of Point Positioning(PPP)and Real-Time Kinematic(RTK),is proposed to provide a centimeter-accuracy positioning service for an unlimited number of ***,the PPP–RTK technique is becoming a promising tool for emerging applications such as autonomous vehicles and unmanned logistics as it has several advantages including high precision,full flexibility,and good *** paper gives a detailed review of PPP–RTK focusing on its implementation methods,recent achievements as well as challenges and ***,the fundamental approach to implement PPP–RTK is described and an overview of the research on key techniques,such as Uncalibrated Phase Delay(UPD)estimation,precise atmospheric correction retrieval and modeling,and fast PPP ambiguity resolution,is ***,the recent efforts and progress are addressed,such as improving the performance of PPP–RTK by combining multi-GNSS and multi-frequency observations,single-frequency PPP–RTK for low-cost devices,and PPP–RTK for vehicle ***,the system construction and applications based on the PPP–RTK method are ***,the main issues that impact PPP–RTK performance are highlighted,including signal occlusion in complex urban areas and atmosphere modeling in extreme weather *** new opportunities brought by the rapid development of low-cost markets,multiple sensors,and new-generation Low Earth Orbit(LEO)navigation constellation are also ***,the paper concludes with some comments and the prospects for future research.

关键词： PPP–RTK Ambiguity resolution Multi-GNSS Smart device Multi-sensor fusion

Analysis of Hydrocarbon Mixture Performance of a Dual-Channel Swirl Engine

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Journal of Thermal Science 2020年第6期29卷 1391-1397页

作者： YUAN Wenhua huang Qilin FU Jun liAO Jingjing li Yu HE Yong ZHANG Zengfeng MA yi School of Mechanical and Energy Engineering Shaoyang UniversityShaoyang 422004China State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China Key Laboratory of Hunan Province for Efficient Power System and Intelligent Manufacturing Shaoyang UniversityShaoyang 422000China

In order to understand and improve the oil and gas mixing performance of a dual-channel vortex chamber diesel engine,the BH175F dual-channel vortex chamber combustion system was used as the research foundation,and the oil-gas mixture process of the combustion system was numerically *** analyzing the cylinder temperature,cylinder pressure,mixing process and combustion process of the combustion system,the mixture performance of the combustion system was *** indicated that:The mixture of the compression Top Dead Center(TDC)started to enter the main combustion chamber through the start-up hole;when the piston reached 4°After Top Dead Center(ATDC),the mixture started to enter the main combustion chamber through the connecting channels A and B,and the high-concentration mixture entered the main combustion from the start-up hole;when the piston continued running down to 20°and 25°ATDC,it could be seen that the main combustion chamber mixture was already relatively uniform;besides,when the equivalence ratio was between 0.8 and 1,the air-ftiel mixture was unevenly distributed in the main combustion *** provides guidance for further improvement of the combustion system.

关键词： gas mixing performance dual-channel vortex chamber combustion system

Strong room-temperature emission from defect states in CVD-grown WSe2 nanosheets

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Nano Research 2018年第7期11卷 3922-3930页

作者： shudong Zhao Lei Tao Peng Miao Xianjie wang Zhiguo liu yi wang Bingsheng li Yu Sui Yang wang Department of Physics Harbin Institute of Technology Harbin 150001 China School of Chemistry and Chemical Engineering Harbin Institute of Technology Harbin 150001 China Academy of Fundamental ond lnterdisciplinary Sciences Harbin Institute of Technology Harbin 150001 China

Monolayer transition metal dichalcogenides （TMDCs）, as direct bandgap semiconductors, show promise for applications in ultra-thin flexible optoelec- tronic devices. However, the optical properties and device performance are greatly affected by defects, such as vacancies, present in these materials. Vacancies exist unavoidably in mechanically exfoliated or grown by chemical vapor deposition （CVD） monolayer TMDCs; therefore, their influence on the electric and optical properties of host materials has been widely studied. Here, we report a new defect state located at 1.54 eV, which is 70 meV lower than the neutral exciton energy in as-prepared WSe2 monolayers grown by CVD. This defect state is clearly observed in photoluminescence （PL） and Raman spectra at ambient conditions. PL mapping, Rarnan mapping, and atomic force microscopy analysis indicate a solid-vapor reaction growth mechanism of the defect state formation. During a certain growth stage, nuclei with the composition of WOxSey do not fully react with the Se vapor, leading to the defect formation. This type of defects permits radiative recombination of bound neutral excitons, which can make the PL intensity as strong as the intrinsic excitation. Our findings reveal a new way to tailor the optical properties of two-dimensional TMDCs without any additional processes performed after growth.

关键词： monolayer WSe2 defects photoluminescence chemical vapordeposition (CVD) growth mechanism

A Review on Metal-Organic Framework-Derived Porous Carbon-Based Novel Microwave Absorption Materials

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Nano-Micro Letters 2021年第4期13卷 1-29页

作者： Zhiwei Zhang Zhihao Cai Ziyuan wang Yaling Peng Lun Xia Suping Ma Zhanzhao yin yi huang National Institute for Advanced Materials Tianjin Key Laboratory of Metal and Molecule Based Material Chemistry Key Laboratory of Functional Polymer MaterialsCollaborative Innovation Center of Chemical Science and Engineering(Tianjin)School of Materials Science and EngineeringNankai UniversityTianjin 300350People’s Republic of China

The development of microwave absorption materials(MAMs) is a considerable important topic because our living space is crowed with electromagnetic wave which threatens human’s *** MAMs are also used in radar stealth for protecting the weapons from being *** nanomaterials were studied as MAMs,but not all of them have the satisfactory ***,metal-organic frameworks(MOFs) have attracted tremendous attention owing to their tunable chemical structures,diverse properties,large specific surface area and uniform pore *** can transform to porous carbon(PC) which is decorated with metal species at appropriate pyrolysis ***,the loss mechanism of pure MOF-derived PC is often relatively *** order to further improve the MA performance,the MOFs coupled with other loss materials are a widely studied *** this review,we summarize the theories of MA,the progress of different MOF-derived PC-based MAMs,tunable chemical structures incorporated with dielectric loss or magnetic loss *** different MA performance and mechanisms are discussed in ***,the shortcomings,challenges and perspectives of MOF-derived PC-based MAMs are also *** hope this review could provide a new insight to design and fabricate MOF-derived PC-based MAMs with better fundamental understanding and practical application.

关键词： Metal-organic frameworks Porous carbon Microwave absorption material Reflection loss Effective absorption bandwidth

Efficacy and safety of adalimumab in comparison to infliximab for Crohn's disease:A systematic review and meta-analysis

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World Journal of Clinical Cases 2022年第18期10卷 6091-6104页

作者： Hua-Hua Yang yi huang Xu-Chun Zhou Ruo-Nan wang Department of Gastroenterology The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Endocrinology Liyuan HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430077Hubei ProvinceChina

BACKGROUND Adalimumab(ADA)and infliximab(IFX)are the cornerstones of the treatment of Crohn’s disease(CD).It remains controversial whether there is a difference in the effectiveness and safety between IFX and ADA for *** To perform a meta-analysis to compare the effectiveness and safety of ADA and IFX in *** Pub Med,Embase,Cochrane library,and Web of Science databases were *** studies were considered for *** primary outcomes were induction of response and remission,maintenance of response and remission,and secondary loss of *** events were secondary *** Fourteen cohort studies were *** was no apparent difference between the two agents in the induction response[odds ratio(OR):1.27,95%confidence interval(CI):0.93-1.74,P=0.14]and remission(OR:1.11,95%CI:0.78–1.57,P=0.57),maintenance response(OR:1.08,95%CI:0.76–1.53,P=0.67)and remission(OR:1.26,95%CI:0.87–1.82,P=0.22),and secondary loss of response(OR:1.01,95%CI:0.65–1.55,P=0.97).Subgroup analysis revealed ADA and IFX had similar rates of response,remission,and loss of response either in anti-tumor necrosis factor-αna?ve or non-na?ve ***,there was a similar result regardless of whether CD patients were treated with optimized therapy,including dose intensification,shortening interval,and combination ***,ADA had a fewer overall adverse events than IFX(OR:0.62,95%CI:0.42–0.91,P=0.02).CONCLUsiON ADA and IFX have similar clinical benefits for anti-tumor necrosis factor-αna?ve or non-na?ve CD *** adverse events rate is higher in patients in the IFX group.

关键词： Crohn disease Adalimumab Infliximab Clinical efficacy Adverse effects Meta-analysis

The input pattern problem on deep learning applied to signal analysis and processing to achieve fault diagnosis

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Science China(Information Sciences) 2019年第12期62卷 269-271页

作者： Hao REN Nan li yi CHAI Jianfeng QU Qiu TANG Lei huang School of Automation Chongqing University Key Laboratory of Complex System Safety and Control Ministry of Education School of Computer Science and Technology Huaiyin Normal University

Dear editor,Generally, one of the most prominent features of modern industrial systems is the massive amount of data collected from various sensors, which poses great challenges to traditional methods of captur-

关键词： The input pattern problem on deep learning applied to signal analysis and processing to achieve fault diagnosis

蠋蝽两种不同释放方法对马尾松毛虫的林间防控效果评价

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中国生物防治学报 2025年第1期41卷 186-192页

作者：邓婉黄科胡倩李罗秀刘清袁洁李密湖南省林业科学院国家林草局南方天敌繁育与应用工程技术研究中心湘乡市林业局湘西土家族苗族自治州林业科学研究所中南林业科技大学湘西土家族苗族自治州凤凰县林峰乡林业管理站

马尾松毛虫是我国的主要森林有害生物之一，一旦暴发成灾则会导致松树大面积死亡，蠋蝽作为一种优良的捕食性天敌昆虫已大规模扩繁成功，近几年农林烟草行业都增加了对其的田间应用效果研究应用和推广，但是在林业上如何应用于马尾松毛... 详细信息

马尾松毛虫是我国的主要森林有害生物之一，一旦暴发成灾则会导致松树大面积死亡，蠋蝽作为一种优良的捕食性天敌昆虫已大规模扩繁成功，近几年农林烟草行业都增加了对其的田间应用效果研究应用和推广，但是在林业上如何应用于马尾松毛虫的林间防控知之甚少。基于此，本研究通过林间罩笼试验和林间直接释放试验分别明确了天敌蠋蝽5龄若虫对马尾松毛虫3龄幼虫的防控效果，结果表明：在食物饱和情况下，蠋蝽5龄若虫对马尾松毛虫3龄幼虫的防控效果随着释放时间的延长显著增强，1号样地从首日的20.34%防治效果增加到49.09%;2号样地从首日的20.69%防治效果到3d后的41.82%；虽然1号样地和2号样地生境条件等差异明显，但在同一释放时间间隔内，蠋蝽5龄若虫对于马尾松毛虫3龄幼虫的防控效果差异不显著。另外在自然条件下松林间释放蠋蝽5龄若虫后15d时可对马尾松毛虫3龄幼虫的校正防效高达63.91%，防治效果都显著优于释放7 d后的结果，表明随着释放时间的延长，防控效果显著增强。本研究表明，天敌昆虫蠋蝽可实现对松林间的马尾松毛虫的种群控制潜能。

关键词：蠋蝽马尾松毛虫生物防治林间释放

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