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Predicting Microbe-Disease Association Based on Heterogeneous Network and Global Graph Feature Learning

Chinese Journal of Electronics 2022年第2期31卷 345-353页

作者： wang yueyue LEI Xiujuan PAN Yi School of Computer Science Shaanxi Normal University Department of Computer Science Georgia State University Faculty of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences

Numerous microbes inhabit human body,making a vast difference in human health. Hence, discovering associations between microbes and diseases is beneficial to disease prevention and treatment. In this study,we develop a prediction method by learning global graph feature on the heterogeneous network(called HNGFL).Firstly, a heterogeneous network is integrated by known microbe-disease associations and multiple *** on microbe Gaussian interaction profile(GIP) kernel similarity, we consider different effects of these microbes on organs in the human body to further improve microbe similarity. For disease similarity network, we combine GIP kernel similarity, disease semantic similarity and disease-symptom similarity. And then, an embedding algorithm called GraRep is used to learn global structural information for this network. According to vector feature of every node, we utilize support vector machine classifier to calculate the score for each microbe-disease pair. HNGFL achieves a reliable performance in cross validation, outperforming the compared methods. In addition, we carry out case studies of three diseases. Results show that HNGFL can be considered as a reliable method for microbe-disease association prediction.

关键词： microorganisms global graph feature learning support vector machines patient diagnosis global structural information disease semantic similarity disease-symptom similarity HNGFL pattern classification graph theory microbe Gaussian interaction profile kernel similarity bioinformatics support vector machine classifier GraRep diseases learning (artificial intelligence) microbe-disease association prediction heterogeneous network Gaussian processes GIP kernel similarity

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Fabrication of polyetheretherketone(PEEK)-based 3D electronics with fine resolution by a hydrophobic treatment assisted hybrid additive manufacturing method

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International Journal of Extreme Manufacturing 2023年第3期5卷 519-532页

作者： Liexin Wu Li Meng yueyue wang Ming Lv Taoyuan Ouyang Yilin wang Xiaoyan Zeng Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074People’s Republic of China

Additive manufacturing(AM)is a free-form technology that shows great potential in the integrated creation of three-dimensional(3D)***,the fabrication of 3D conformal circuits that fulfill the requirements of high service temperature,high conductivity and high resolution remains a *** this paper,a hybrid AM method combining the fused deposition modeling(FDM)and hydrophobic treatment assisted laser activation metallization(LAM)was proposed for manufacturing the polyetheretherketone(PEEK)-based 3D electronics,by which the conformal copper patterns were deposited on the 3D-printed PEEK parts,and the adhesion between them reached the 5B high ***,the 3D components could support the thermal cycling test from-55℃ to 125℃ for more than 100 ***,the application of a hydrophobic coating on the FDM-printed PEEK before LAM can promote an ideal catalytic selectivity on its surface,not affected by the inevitable printing borders and pores in the FDM-printed parts,then making the resolution of the electroless plated copper lines improved *** consequence,Cu lines with width and spacing of only60μm and 100μm were obtained on both as-printed and after-polished PEEK ***,the potential of this technique to fabricate 3D conformal electronics was demonstrated.

关键词： PEEK fused deposition modeling hydrophobic treatment laser activation metallization integrated manufacturing of 3D electronics resolution

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Influence of Kyanite Content on Microstructures and Properties of Castables Containing Spherical Lightweight Mullite Aggregates

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China's Refractories 2017年第2期26卷 39-43页

作者： wang yueyue YAN Wen LI Nan The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081China

Five lightweight mullite castables were prepared using the lightweight mullite aggregate（M45A） with narrow particle size distribution and spherical shape,mullite powder（M45P）,kyanite powder,microsilica and Secar 71 cement as raw materials. After the specimens fired at 1100 ℃,1200 ℃ and 1300 ℃ for 3h,respectively,the effects of kyanite contents（ 8%,10%,12%,14%,16% by mass） on the physical properties,phase composition and microstructures were investigated through an X-ray diffractometer（ XRD）,a scanning election microscopy（ SEM） and a microscopy measurement method,etc. The results show that,for the specimens fired at 1300 ℃ with the kyanite content from 8%to16%, the bulk densities and apparent porosities change little,but the cold modulus of rupture and the crushing strengths decrease significantly,and the linear change rates increase from-0.87% to 0.64%. The most apposite mode is the specimen containing 12% kyanite fired at 1300 ℃, which has a high crushing strength of 29.3 MPa,a low linear change of 0.18%,an apparent porosity of 36.8% and a bulk density of 1.73 g/cm^3.

关键词： spherical lightweight mullite aggregate kyanite content lightweight castable microstructure physical property

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Plasmon enhancement for Vernier coupled single-mode lasing from ZnO/Pt hybrid microcavities

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Nano Research 2017年第10期10卷 3447-3456页

作者： yueyue wang Feifei Qin Junfeng Lu Jitao Li Zhu Zhu Qiuxiang Zhu Ye Zhu Zengliang Shi Chunxiang Xu State Key Laboratory of Bioelectronics School of Biological Science & Medical Engineering Southeast University Nanjing 210096 China School of Sciences Zhejiang A&F University Lin'an 311300 China

It is essential to develop a single mode operation and improve the performance of lasing in order to ensure practical applicability of microlasers and nanolasers. In this paper, two hexagonal microteeth with varied nanoscaled air-gaps of a ZnO microcomb are used to construct coupled whispering-gallery cavities. This is done to achieve a stable single mode lasing based on Vernier effect without requiring any complicated or sophisticated manipulation to achieve positioning with nanoscale precision. Optical gain and the corresponding ultraviolet lasing performance were improved greatly through coupling with localized surface plasmons of Pt nanoparticles. The ZnO/Pt hybrid microcavities achieved a seven-fold enhancement of intensity of single mode lasing with higher side- mode suppression ratio and lower threshold. The mechanism that led to this enhancement has been described in detail.

关键词： ZnO/Pt microcavities whispering-gallery-mode single mode lasing Vernier effect surface plasmon coupling ZnO microrod

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Plasmon-enhanced ZnO whispering-gallery mode lasing

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Nano Research 2018年第6期11卷 3050-3064页

作者： Chunxiang Xu Feifei Qin Qiuxiang Zhu Junfeng Lu yueyue wang Jitao Li Yi Lin Qiannan Cui Zengliang Shi Arumugam Gowri Manohari State Key Laboratory of Bioelectronics Southeast University Nanjing 210096 China College of Information and Electronic Engineering Hunan City University Yiyang 413000 China Belling Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences Beijing 100083 China School of Sciences Zhejiang A&F University Hangzhou 311300 China School of Physics and Telecommunications Engineering Zhoukou Normal University Zhoukou 456001 China Department of Mathematics and Physics Huaiyin Institute of Technology Huaiyin 223306 China

Collaborative enhancements from surface plasmons （SPs） and whispering-gallery modes （WGMs） can induce intense near-field effects with high spatial localization around the surface of a semiconducting material. One can construct a highly efficient hybrid microcavity using semiconducting materials through resonant coupling between SPs and WGMs. Hexagonal ZnO micro-/nanostructures, which have been employed as natural WGM microcavities for ultraviolet （UV） lasing, can be used as ideal platforms to construct such hybrid microcavities. Here, we comprehensively review the recent efforts for improving lasing performance by resonant coupling between SPs and WGMs. Traditional SPs originating from various metals as well as novel SPs originating from atomic layers such as graphene are considered. Moreover, we discuss the mechanism of light-matter interactions beyond the improvements in lasing performance.

关键词： ZnO microcavity surface plasmon whispering-gallery mode

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Length-dependent alignment of large-area semiconducting carbon nanotubes self-assembly on a liquid–liquid interface

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Nano Research 2023年第1期16卷 1568-1575页

作者： Haijian Wen Jian Yao Yijun Li Yahui Li Leitao Cao Wanquan Chi yueyue wang Hehua Jin Song Qiu Jianshi Tang Qingwen Li School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China Key Laboratory of Multifunctional and Smart Systems Division of Advanced MaterialsSuzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China School of Integrated Circuits Beijing Innovation Center for Future ChipsBNRistTsinghua UniversityBeijing 100084China

Aligned arrays of semiconducting carbon nanotubes(s-CNTs)with high homogenous density and orientation are urgently needed for high-performance carbon-based ***,a length-controlled approach using combined technologies was developed to regulate the s-CNT length and reduce the length *** impact of different lengths and length distributions was studied during aligned self-assembly on a liquid–liquid confined interface was *** results show that short s-CNTs with a narrow distribution have the best alignment uniformity over the large *** optimized and aligned s-CNT array can reach a density as high as 100 CNTs·μm−1 on a 4-inch *** field-effect transistor(FET)performance of these optimized s-CNT arrays was 64%higher than arrays without *** study clarified that rational control of s-CNTs with desired length and length distribution on the aligned self-assembly process within the liquid–liquid confined *** results illustrate a solid foundation for the application of emerging carbon-based electronics.

关键词： carbon nanotube aligned array length-controlled self-assembly liquid-liquid interface

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Stabilization of heavy metals in sediments:A bioavailability-based assessment of carbon adsorbent efficacy using diffusive gradients in thin films

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Aquaculture and Fisheries 2021年第6期6卷 601-608页

作者： Yiqin Chen yueyue wang Ruyi Zheng Ju Wen Juan-Ying Li Qian wang Jie Yin College of Marine Ecology and Environment Shanghai Ocean UniversityShanghai201306China

This study investigated the effectiveness of carbon adsorbents as remediation material for sediments contaminated with heavy metals and the feasibility of utilizing diffusive gradients in thin films(DGT)as a biomimetic tool to estimate the accumulation of heavy metals in Venerupis philippinaram(Manila clam).The results showed that carbon materials had significant inhibitory effects(14.0-53.0%)on the enrichment of heavy metals in organisms and the order of increasing overall inhibitory effect was:charcoal,peat,activated carbon,and *** were significant correlations(P<0.0001)between the four heavy metals accumulated in Venerupis philippinaram and those accumulated in DGT devices after 28 days in the *** concentrations of heavy metals enriched in DGT(5.4-42.0%)were less than accumulations in Venerupis *** results of in situ DGT applications showed significant correlations between the amount accumulated in DGT and the acid-soluble portion in sediments for both Cu and Pb,with positive linear correlations and R-squares of 0.97 and 0.92,*** results supported the notion that a DGT device can be used as a biomimetic tool that predicts and monitors the accumulation of heavy metals in aquaculture *** studies should focus on improving the stabilization of heavy metals in sediments using different types of carbon sorbents,as well as minimizing simulation deviations using DGT.

关键词： Carbon amendment sediment remediation DGT Venerupis philippinaram Heavy metals Bioavailability Bioaccumulation

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利用热脉冲技术测量土壤表层含水率

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农业工程学报 2015年第2期31卷 72-78页

作者：张晓王月月任图生中国林业科学院荒漠化研究所北京100091 中国农业大学土壤与水科学系北京100193

准确测定表层土壤水分对陆地-大气间水热交换研究具有重要意义。由于对土壤结构影响轻微,热脉冲技术在原位监测含水率方面具有较大优越性,但目前田间应用集中在5 cm以下土层。该研究利用多针热脉冲传感器测定土壤容积热容量,然后基于热... 详细信息

准确测定表层土壤水分对陆地-大气间水热交换研究具有重要意义。由于对土壤结构影响轻微,热脉冲技术在原位监测含水率方面具有较大优越性,但目前田间应用集中在5 cm以下土层。该研究利用多针热脉冲传感器测定土壤容积热容量,然后基于热脉冲含水率法和热脉冲含水率变化法分别得到了3、9、21和39 mm的土壤含水率。结果表明,与烘干法含水率比较,热脉冲含水率变化法含水率在4个深度的均方根误差分别为0.022、0.006、0.004和0.006 m3/m3,均小于相应深度上热脉冲含水率法含水率的均方根误差。另外,热脉冲含水率变化法也降低了4个热脉冲传感器测定含水率的变异性。因此,热脉冲技术能够监测表层的土壤水分动态,表层土壤含水率的均方根误差在0.022 m3/m3以内。

关键词：土壤水分热传导热脉冲技术表层

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Dual channel modeling of SCR denitrification system for coke oven flue gas

Dual channel modeling of SCR denitrification system for coke...

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第43届中国控制会议

作者： yueyue wang Linlin Qin Chun Shi Gang Wu Department of Automation University of Science and Technology of China

Establishing an accurate mathematical model for the Selective Catalytic Reduction(SCR) denitrification system of coke oven flue gas is pivotal for utilizing advanced process control *** this paper,a modeling approach grounded in field data is *** ensure the model completeness and reduce modeling intricacies,the system is divided into process and disturbance channels,each yielding a Single Input Single Output(SISO) *** response to the periodic oscillations caused by coke oven reversals,Controlled Auto Regression Integrated Moving Average(CARIMA) models are compared with Controlled Auto Regression Moving Average(CARMA),pushing the boundaries of conventional *** structure and parameters of the models are identified utilizing the batch least squares method *** make full use of the continuous stream of site data,Recursive Least Squares with Forgetting Factor(FFRLS) is also utilized to identify the *** convergence is ensured and the matrix P is monitored through the introduction of an intelligent supervision *** the frequency domain,an analysis of model parameters is conducted,leveraging physical properties to refine model *** rigorous cross-validation,the efficacy of the established models is ***,the process channel model achieves an MSE of approximately 8 and an MRE of 2.7%,while the disturbance channel model exhibits an MSE of around 2.8 and an MRE of 1.3%.

关键词： Coke oven SCR denitrification CARMA CARIMA Least Squares

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基于SWAT模型的马莲河流域水沙变化及对人类活动的响应

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水利规划与设计 2025年第1期 5-12页

作者：樊尚斌汪月月周颖马金珠平凉市水资源中心兰州大学资源环境学院/西部环境教育部重点实验室

为定量分析马莲河流域水沙时空变化特征及其对人类活动的响应，文章构建SWAT分布式水文模型，对流域出口水文站雨落萍站2006—2019年的逐月径流量与输沙量进行模拟，模型验证期R2和NS均满足模型精度要求。在此基础上，对马莲河流域模拟... 详细信息

为定量分析马莲河流域水沙时空变化特征及其对人类活动的响应，文章构建SWAT分布式水文模型，对流域出口水文站雨落萍站2006—2019年的逐月径流量与输沙量进行模拟，模型验证期R2和NS均满足模型精度要求。在此基础上，对马莲河流域模拟期的降水量、蒸散发、径流深与泥沙负荷的分布格局进行分析，发现流域下游干流处是主要的产流产沙区，且流域月累计降水、月径流量与月输沙量之间响应较好。分析人类活动对水沙变化的影响，土地利用类型中耕地的减少与草地面积的增加以及淤地坝建设对流域减水减沙等水保效益具有显著效果。

关键词：马莲河流域 SWAT模型径流泥沙人类活动

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