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Successful emergency surgical intervention in acute non-STsegment elevation myocardial infarction with rupture:A case report

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World Journal of Clinical Cases 2025年第4期13卷 41-47页

作者： Xing-Po Li Zi-shan wang Hong-Xia yu shan-shan wang Department of Cardiovascular Medicine Huantai County Hospital of Traditional Chinese MedicineZibo 256400Shandong ProvinceChina Department of Cardiovascular Medicine Zibo Hospital of Integrated Traditional Chinese and Western MedicineZibo 255500Shandong ProvinceChina

BACKGROUND The incidence of acute myocardial infarction(AMI)is rising,with cardiac rupture accounting for approximately 2%of deaths in patients with acute ST-segment elevation myocardial infarction(STEMI).Ventricular free wall rupture(FWR)occurs in approximately 2%of AMI patients and is notably rare in patients with *** of cardiac rupture include left ventricular FWR,ventricular septal rupture,and papillary muscle *** FWR usually leads to acute cardiac tamponade or electromechanical dissociation,where standard resuscitation efforts may not be *** septal rupture and papillary muscle rupture often result in refractory heart failure,with mortality rates over 50%,even with surgical or percutaneous repair *** SUMMARY We present a rare case of an acute non-STEMI patient who suffered sudden FWR causing cardiac tamponade and loss of consciousness immediate before undergoing coronary *** resuscitation and emergency open-heart repair along with coronary artery bypass grafting resulted in successful patient *** This case emphasizes the risks of AMI complications,shares a successful treatment scenario,and discusses measures to prevent such complications.

关键词： Acute non-ST segment elevation myocardial infarction Cardiac rupture Acute myocardial infarction Free wall rupture Case report

Relationship between Trp64Arg mutation in the β3-adrenergic receptor gene and metabolic syndrome： a seven-year follow-up study

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Chinese Medical Journal 2010年第17期123卷 2375-2378页

作者： ZHU Lue-yun HU Li-ye LI Xiao-ling wang Guang-yu shan Wei MA Li-cheng wang Xiu-hui Department of Endocrinology Bethune International Peace Hospital Shijiazhuang Hebei 050082 China

Background It has been shown that the β3-adrenergic receptor （β3-AR） gene Trp64Arg mutation was closely related to obesity and insulin resistance, and may be related to the prevalence of metabolic syndrome （MS）. The aim of this study was to investigate the relationship between the 33-AR gene mutation and the prevalence of MS. Methods A seven-year follow-up study was initiated in 2000, with 496 samples of simplex obese subjects （body mass index ≥25 kg/m2） and 248 normal-weight subjects. According to the β3-AR genotypes, the subjects were classified as Trp64 homozygote group and Arg64 carrier group and after 7 years the prevalence of MS was determined. Results According to the baseline profile, there were no significant differences in the adiposity, blood pressure, lipid profile, fasting plasma glucose and fasting insulin between Trp64 homozygote group and Arg64 carrier group either in obesity or normal-weight subjects. The results of follow-up study indicated that in obese men the prevalence rate of MS was much higher in Arg64 carrier group than that in Trp64 homozygote group （54.76% vs. 40.85%, P 〈0.05）, but there was no statistical difference in women of the above groups. The prevalence rate of MS in obese men of both Trp64 homozygote group and Arg64 carrier obese group were obviously higher than that in women of the above groups （40.85% vs. 18.27% and 54.76% vs 21.28%, all P 〈0.005）. Differences were not statistically significant in the prevalence of MS for normal weight Trp64 homozygote group and normal weight Arg64 carrier group, either between men, between women, or between men and women. Comparison of populations indicated that no matter with the β3-AR gene mutation or not, the prevalence of MS in obese subjects was significantly higher than normal weight subjects （X2=28.240 and x2=15.586, all P 〈0.005）. Logistic analysis showed that the mutation of β3-AR gene was associated with the prevalence of MS in men.

关键词： metabolic syndrome β3-adrenergic receptor polymorphism prospective study

In vitro pancreas duodenal homeobox-1 enhances the differentiation of pancreatic ductal epithelial cells into insulin-producing cells

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World Journal of Gastroenterology 2007年第39期13卷 5232-5237页

作者： Tao Liu Chun-You wang Feng yu shan-Miao Gou He-Shui Wu Jiong-Xin Xiong Feng Zhou Department of Pancreatic Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Hubei Province China

AIM: To observe whether pancreatic and duodenal homeobox factor-1 enhances the differentiation of pancreatic ductal epithelial cells into insulin-producing cells in vitro. METHODS: Rat pancreatic tissue was submitted to digestion by collegenase, ductal epithelial cells were separated by density gradient centrifugation and then cultured in RPMI1640 medium with 10% fetal bovine serum. After 3-5 passages, the cells were incubated in a six-well plate for 24 h before transfection of recombination plasmid XlHbox8VP16. Lightcycler quantitative real-time RT-PCR was used to detect the expression of PDX-1 and insulin mRNA in pancreatic epithelial cells. The expression of PDX-1 and insulin protein was analyzed by Western blotting. Insulin secretion was detected by radioimmunoassay. Insulin- producing cells were detected by dithizone-staining. RESULTS: XlHbox8 mRNA was expressed in pancreatic ductal epithelial cells. PDX-1 and insulin mRNA as well as PDX-1 and insulin protein were signifi cantly increased in the transfected group. The production and insulin secretion of insulin-producing cells differentiated from pancreatic ductal epithelial cells were higher than those of the untransfected cells in vitro with a significant difference (1.32 ± 0.43 vs 3.48 ± 0.81, P < 0.01 at 5.6 mmol/L; 4.86 ± 1.15 vs 10.25 ± 1.32, P < 0.01 at 16.7 mmol/L). CONCLUSION: PDX-1 can differentiate rat pancreaticductal epithelial cells into insulin-producing cells in vitro. In vitro PDX-1 transfection is a valuable strategy for increasing the source of insulin-producing cells.

关键词： Pancreatic ductal epithelial cells Islet Differentiation Pancreas duodenal homeobox-i

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少数民族大学生阅读倾向调查分析

云南民族大学学报（哲学社会科学版） 2007年第6期24卷 150-152页

作者：王育珊云南民族大学图书馆云南昆明650031

通过对少数民族大学生阅读倾向的调查分析,针对少数民族大学生在阅读中存在的阅读主动性不够、阅读无计划、阅读面狭窄、阅读行为自闭、获取阅读信息手段单一等问题,提出高校图书馆导读工作的应对措施。

关键词：少数民族大学生阅读倾向导读

大型火电机组在AGC运行方式下的控制特性分析

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电网技术 2005年第18期29卷 12-16页

作者：李卫华王玉山华北电力科学研究院有限责任公司北京市西城区100045

结合华北电网自动发电控制(AGC)的实际运行情况,介绍了AGC控制方式、华北电网对AGC投运机组的控制指标要求以及机组的协调控制系统设计方案,分析了华北电网中的大型火电机组在AGC运行过程中遇到的问题,并提出了提高机组在AGC运行方式下... 详细信息

结合华北电网自动发电控制(AGC)的实际运行情况,介绍了AGC控制方式、华北电网对AGC投运机组的控制指标要求以及机组的协调控制系统设计方案,分析了华北电网中的大型火电机组在AGC运行过程中遇到的问题,并提出了提高机组在AGC运行方式下的控制特性的方法和建议。

关键词：电力系统调度自动化华北电网自动发电控制(AGC) 大型火电机组控制特性

P2Y1 receptor in Alzheimer’s disease

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Neural Regeneration Research 2025年第2期20卷 440-453页

作者： shan Luo Yifei wang Tatsuhiro Hisatsune Department of Integrated Biosciences The University of TokyoKashiwaJapan

Alzheimer’s disease is the most frequent form of dementia characterized by the deposition of amyloid-beta plaques and neurofibrillary tangles consisting of hyperphosphorylated *** amyloid-beta plaques has been a primary direction for developing Alzheimer’s disease treatments in the last ***,existing drugs targeting amyloid-beta plaques have not fully yielded the expected results in the clinic,necessitating the exploration of alternative therapeutic *** evidence unravels that astrocyte morphology and function alter in the brain of Alzheimer’s disease patients,with dysregulated astrocytic purinergic receptors,particularly the P2Y1 receptor,all of which constitute the pathophysiology of Alzheimer’s *** receptors are not only crucial for maintaining normal astrocyte function but are also highly implicated in neuroinflammation in Alzheimer’s *** review delves into recent insights into the association between P2Y1 receptor and Alzheimer’s disease to underscore the potential neuroprotective role of P2Y1 receptor in Alzheimer’s disease by mitigating neuroinflammation,thus offering promising avenues for developing drugs for Alzheimer’s disease and potentially contributing to the development of more effective treatments.

关键词： astrocytes neuroinflammation P2Y1 receptor purinergic receptor

贮藏种子的啮齿动物对油茶种子沉积形式的影响

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Acta Botanica Sinica 2004年第7期46卷 773-779页

作者：王玉山肖治术张知彬中国科学院动物研究所，农业虫鼠害综合治理国家重点实验室，北京l00080

种子沉积的质量常常涉及种子扩散作用者(如鸟类和小型啮齿动物)对生境和微生境的选择以及种子沉积的形式(如种子埋藏)。然而，很少的研究涉及到种子在离开母树后被这些动物沉积在何处。在四川省都江堰一个实验林场的2个林分(次生林和原... 详细信息

种子沉积的质量常常涉及种子扩散作用者(如鸟类和小型啮齿动物)对生境和微生境的选择以及种子沉积的形式(如种子埋藏)。然而，很少的研究涉及到种子在离开母树后被这些动物沉积在何处。在四川省都江堰一个实验林场的2个林分(次生林和原生林)内，通过追踪用带编号的金属薄片标记的油茶(Camellia oleiferaAbel．)种子的命运，研究了贮藏种子的啮齿动物对种子沉积的影响。研究发现：在2个林分内，80％以上的种子被很好地埋藏在0.60mm深的土壤中，而小部分种子则被放置在地表(但有少量落叶遮盖)。小型啮齿动物喜好在灌丛下或灌丛边缘贮藏和取食种子，可能是在这样的微生境下它们在觅食时将遭遇较小的捕食风险。研究还发现，贮藏点的微生境分布随贮藏点等级而逐渐变化：在两个林分内较高等级的贮藏点(如次贮藏点和三级贮藏点)比初级贮藏点有更多的种子被贮藏在灌丛下或灌丛边缘。这表明，啮齿动物对油茶种子的埋藏可能更有益于种子的存活、萌发以及幼苗的建成。啮齿动物将散落在母树下或其附近的油茶种子扩散到不同的微生境，这可能有利于他们遭遇到更多的适宜环境而萌发，实现幼苗补充。

关键词：种子埋藏微生境选择分散贮藏种子扩散幼苗补充小型啮齿动物

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民族地区农村文化产业发展路径探析

西北农林科技大学学报（社会科学版） 2016年第6期16卷 154-160页

作者：王丹玉王山奉公中国农业大学人文与发展学院北京100193 大北农集团研究院北京100872

随着新型城镇化建设的不断深入,文化资源产业化对于民族地区农村经济发展和农民生活水平提高具有重要的现实意义。少数民族地区农村文化资源的独特性与排他性为农村文化产业的发展奠定了基础。但是,民族地区农村经济发展落后,文化生态... 详细信息

随着新型城镇化建设的不断深入,文化资源产业化对于民族地区农村经济发展和农民生活水平提高具有重要的现实意义。少数民族地区农村文化资源的独特性与排他性为农村文化产业的发展奠定了基础。但是,民族地区农村经济发展落后,文化生态发展失衡,文化空间日益萎缩,文化传承与创新意识薄弱,人才队伍建设滞后等困境仍然是制约农村文化产业发展的多重阻碍。因此,为了促进民族地区农村文化产业更好更快的发展,应构建民族文化传承与保护机制,培育文化产业发展意识,加强基础设施和人才队伍建设,完善产业组织建设,为农村文化产业的发展提供保障。

关键词：新型城镇化文化产业民族文化民族地区

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奇台县某金矿矿石特性及可选性试验研究

新疆地质 2012年第2期30卷 238-241页

作者：王玉山王勇新疆矿产实验研究所新疆乌鲁木齐830000

通过对金矿石化学及矿物组成、自然金形态、嵌布粒度、嵌布方式等深入研究,查明了该矿石性质。利用浮选法和氰化法进行可选性试验研究,浮选试验精矿品位为46.86 g/t,回收率达85.14%,氰化试验最高浸出率96.38%。综合分析认为,采用浮选法... 详细信息

通过对金矿石化学及矿物组成、自然金形态、嵌布粒度、嵌布方式等深入研究,查明了该矿石性质。利用浮选法和氰化法进行可选性试验研究,浮选试验精矿品位为46.86 g/t,回收率达85.14%,氰化试验最高浸出率96.38%。综合分析认为,采用浮选法选矿较合理。

关键词：奇台县金矿嵌布粒度嵌布方式浮选