检索结果-南通市图书馆

维普期刊数据库博看期刊

芦可替尼联合低剂量后置环磷酰胺预防恶性血液病单倍体造血干细胞移植急性移植物抗宿主病的临床研究

在线全文

学校读者我要写书评

暂无评论

中华血液学杂志 2024年第2期45卷 128-133页

作者：李小平李玉刘林袁忠涛王佑铖董彦成张定松冯静陈应年王三斌联勤保障部队第九二〇医院血液科昆明650000

目的评估芦可替尼联合低剂量后置环磷酰胺为基础的急性移植物抗宿主病(GVHD)预防方案在恶性血液病单倍体造血干细胞移植(haplo-HSCT)中的临床疗效和安全性。方法收集2022年1月至12月在联勤保障部队第九二〇医院行haplo-HSCT患者,所有患... 详细信息

目的评估芦可替尼联合低剂量后置环磷酰胺为基础的急性移植物抗宿主病(GVHD)预防方案在恶性血液病单倍体造血干细胞移植(haplo-HSCT)中的临床疗效和安全性。方法收集2022年1月至12月在联勤保障部队第九二〇医院行haplo-HSCT患者,所有患者在预处理后予以减低剂量后置环磷酰胺、兔抗人胸腺细胞免疫球蛋白、芦可替尼、甲氨蝶呤及环孢素A、霉酚酸酯等预防急性GVHD,分析所有患者移植结局、并发症及生存情况。结果共纳入52例haplo-HSCT患者,男29例(55.8%),女23例(44.2%),中位年龄为28(5~59)岁。急性髓系白血病25例,急性淋巴细胞白血病17例、骨髓增生异常综合征6例、慢性髓性白血病2例,骨髓增殖性肿瘤2例。98.1%的患者实现正常植入,其中Ⅱ~Ⅳ、Ⅲ/Ⅳ度急性GVHD发生率分别为19.2%(95%CI 8.2%~30.3%)、7.7%(95%CI 0.2%~15.2%)。未发生严重消化道黏膜炎。EB病毒、巨细胞病毒再激活率分别为40.4%、21.3%。9.6%的患者在随访期间复发,移植后1年总生存率、无进展生存率、非复发死亡率分别为86.5%(95%CI 76.9%~96.1%)、78.8%(95%CI 67.4%~90.3%)、11.5%(95%CI 2.6%~20.5%)。结论在恶性血液病患者haplo-HSCT中,芦可替尼联合减低剂量后置环磷酰胺为基础的急性GVHD预防方案可有效控制急性GVHD且安全性良好。

关键词：芦可替尼移植物抗宿主病单倍体造血干细胞移植环磷酰胺

在线全文

学校读者我要写书评

暂无评论

FPC板电镀镍金焊盘掉件失效原因分析

电子产品可靠性与环境试验 2024年第1期42卷 91-95页

作者：汪洋李晓倩张宣王有成工业和信息化部电子第五研究所华东分所江苏苏州215011

柔性电路板(FPC)广泛地应用于各种电子产品中,随着电子产品的小型化,表面贴装技术(SMT)普遍地应用于电路装连,以实现元器件间的电气导通和信号传输。现介绍一种电镀镍金FPC板在SMT后出现掉件的失效概况,通过体视显微镜、剪切力测试、扫... 详细信息

柔性电路板(FPC)广泛地应用于各种电子产品中,随着电子产品的小型化,表面贴装技术(SMT)普遍地应用于电路装连,以实现元器件间的电气导通和信号传输。现介绍一种电镀镍金FPC板在SMT后出现掉件的失效概况,通过体视显微镜、剪切力测试、扫描电子显微镜(SEM)、能谱仪(EDS)和X射线荧光测厚仪(XRF)等测试方法和表征手段,对失效样品进行了系统分析,发现掉件是因为焊盘镀镍层和底铜层之间结合不良、存在明显缝隙所致,而结合力差主要与电镀过程控制不当有关,如电镀前清洗不彻底等。

关键词：失效分析掉件电镀Ni/Au 柔性电路板

益生菌在水产养殖可持续发展中的应用现状及展望

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

水产学报 2024年第3期48卷 3-15页

作者：赵勇段为旦王友成苏明陶倩张昭寰潘迎捷刘智俊上海海洋大学食品学院农业农村部(上海)水产品贮藏保鲜质量安全风险评估实验室上海水产品加工及贮藏工程技术研究中心上海睿婕水产养殖专业合作社上海市青浦区水产技术推广站上海市水产研究所上海市水产技术推广站

水产养殖在全球粮食安全中发挥着至关重要的作用，为人类提供优质蛋白源持续稳定供应提供了重要保障。益生菌是一类可用于水产养殖的有益微生物，不仅能够提高水产动物的生长性能、免疫能力，而且具有抑制致病菌、改善养殖水质等功效。... 详细信息

水产养殖在全球粮食安全中发挥着至关重要的作用，为人类提供优质蛋白源持续稳定供应提供了重要保障。益生菌是一类可用于水产养殖的有益微生物，不仅能够提高水产动物的生长性能、免疫能力，而且具有抑制致病菌、改善养殖水质等功效。益生菌在水产养殖中的推广应用可促进水产养殖业的健康可持续发展。因此，本文首先介绍了水产养殖中益生菌的定义与来源，详细阐述了益生菌对水产可持续养殖的意义以及益生菌在水产养殖中的实际应用，并对其未来研究方向进行了展望，以期为益生菌在水产养殖可持续发展中的推广和应用提供可靠的理论依据。

关键词：水产养殖益生菌益生功效可持续发展

Genesis of granular calcite in lacustrine fine-grained sedimentary rocks and its indication to volcanichydrothermal events: A case study of Permian Lucaogou Formation in Jimusar Sag, Junggar Basin, NW China

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Petroleum Exploration and Development 2023年第3期50卷 615-627页

作者： LI Ke XI Kelai CAO Yingchang wang youcheng LIN Miruo Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)Qingdao 266580China

Granular calcite is an authigenic mineral in fine-grained sedimentary *** observation,thin section observation,cathodoluminescence analysis,fluid inclusion analysis,scanning electron microscope(SEM),and isotopic composition analysis were combined to clarify the genesis of granular calcite in the lacustrine fine-grained sedimentary rocks of the Permian Lucaogou Formation in the Jimusar Sag,Junggar *** is found that the granular calcite is distributed with laminated characteristics in fine-grained sedimentary rocks in tuffite zones(or the transitional zone between tuffite and micritic dolomite).Granular calcite has obvious cathodoluminesence band,and it can be divided into three ***-Ⅰ calcite,with non-luminesence,high content of Sr element,inclusions containing Cos,and homogenization temperature higher than 170℃,was directly formed from the volcanic-hydrothermal ***-Ⅱ calcite,with bright yellow luminescence,high contents of Fe,Mn and Mg,enrichment of light rare earth elements(LREEs),and high homogenization temperature,was formed by recrystallization of calcareous edges from exhalative hydrothermal ***-IlI calcite,with dark orange luminescence band,high contents of Mg,P,V and other elements,no obvious fractionation among LREEs,and low homogenization temperature,was originated from diagenetic transformation during *** granular calcite appears regularly in the vertical direction and its formation temperature decreases from the center to the margin of particles,providing direct evidences for volcanic-hydrothermal events during the deposition of the Lucaogou *** volcanic-hydrothermal event was conducive to the enrichment of organic matters in fine-grained sedimentary rocks of the Lucaogrou Formation,and positive to the development of high-quality source *** volcanic-hydrothermal sediments might generate intergranular pores/fractures during the evolution,creating conditions for the self-generation and sel

关键词： fine-grained sedimentary rocks calcite origin volcanic-hydrothermal event event deposition Permian Lucaogrou Formation Jimusar Sag Junggar Basin

Controlling the lateral and vertical dimensions of Bi2Se3 nanoplates via seeded growth

在线全文

学校读者我要写书评

暂无评论

Nano Research 2015年第1期8卷 246-256页

作者： Awei Zhuang Yuzhou Zhao Xianli Liu Mingrui Xu youcheng wang Unyong Jeong Xiaoping wang Jie Zeng Hefei National Laboratory for Physical Sciences at the Microscale Collaborative Innovation Center of Suzhou Nano Science and Technology Center of Advanced Nanocatalysis (CAN-USTC) & Department of Chemical Physics University of Science and Technology of China Hefei Anhui 230026 P. R. China Department of Materials Science and Engineering Yonsei University 134 Shinchon-dong Seoul Korea

Modulation of the morphology of nanostructures is often a rewarding but challenging task. We have employed the seeded growth method and induced kinetic control to synthesize Bi2Se3 nanoplates with modifiable morphology. By manipulating the rate at which precursor solutions were injected into seeds solution with syringe pumps, two distinctive growth modes could be realized. With a fast injection, the thickness of Bi2Se3 nanoplates slightly increased from N7.5 nm （seeds） to -9.5 nm while the edge length grew up from ~160 nm （seeds） to N12 ~tm, after 6 successive rounds of seeded growth. With a slow injection, the thickness and edge length increased simultaneously to -35 nm and -6 b^m after 6 rounds of growth, respectively. These two modes could be viewed as a competition between atomic deposition and surface migration. The products showed interesting, thickness-dependent Raman properties. In addition, NIR transparent, highly conductive and flexible Bi2Se3 thin films with different thicknesses were constructed by the assembly of the as-synthesized Bi2Se3 nanoplates. This approach based on seeded growth and kinetic control can significantly promote the development of versatile nanostructures with diverse morphology.

关键词： bismuth selenide nanoplates seeded growth kinetic control

Concave Cu-Pd bimetallic nanocrystals： Ligand-based Co-reduction and mechanistic study

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2015年第7期8卷 2415-2430页

作者： Lan Zhang Hongyang Su Mei Sun youcheng wang Wenlong Wu Taekyung Yu Jie Zeng Hefei National Laboratory for Physical Sciences at the Microscale Key Laboratory of Strongly-Coupled Quantum Matter Physics of Chinese Academy of Sciences Center of Advanced Nanocatalysis (CAN-USTC) & Department of Chemical Physics University of Science and Technology of China Hefei 230026 China Department of Chemical Engineering College of Engineering Kyung Hee University Yongin 446-701 Republic of Korea

The synthesis of highly uniform alloy nanocrystals with a concave feature is desirable for applications in catalysis but is an arduous task. This article proposes an initiative protocol for the fabrication of novel Cu-Pd alloy nanocrystals, wherein the volume of decylamine （DA） in the reaction system was found to greatly influence the formation of different morphologies, including the tetrahedron （TH）, concave tetrahedron （CTH）, rhombohedral-tetrapod （RTP）, and tetrapod （TP）. The alloy structure of the products arises from the coordination interaction between the DA and metal ions, which affects the reduction potential of Cu and Pd species, and thus yields co-reduction. Other reaction parameters, such as the type of ligand, amount of reductant, and temperature, were also altered to study the growth mechanism, yielding consistent conclusions in the diffusion-controlled regime. As a catalyst, 48-nm Cu-Pd concave tetrahedral nanocrystals were highly active for the hydrogenation of 3-nitrostyrene and exhibited 〉99.9% chemoselectivity to C=C instead of-NO2.

关键词： Cu-Pd alloy,CO-redUction,concave mechanistic study hydrohenation of 3-nitrostytene

One-pot synthesis of Bi2Se3 nanostructures with rationally tunable morphologies

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2015年第11期8卷 3612-3620页

作者： Xianli Liu Jinwei Xu Zhicheng Fang Lin Lin Yu Qian youcheng wang Chunmiao Ye Chao Ma Jie Zeng Hefei National Laboratory for Physical Sciences at the Microscale Key Laboratory of Strongly-Coupled Ouantum Matter Physics of Chinese Academy of Sciences Center of Advanced Nanocatalysis (CAN-USTC) & Department of Chemical Physics University of Science and Technology of China Hefei 230026 China

Shape control has proven to be a powerful and versatile means of tailoring the properties of Bi2Se3 nanostructures for a wide variety of applications. Here, three different Bi2Se3 nanostructures, i.e., spiral-type nanoplates, smooth nanoplates, and dendritic nanostructures, were prepared by manipulating the supersaturation level in the synthetic system. This mechanism study indicated that, at low supersaturation, defects in the crystal growth could cause a step edge upon which Bi2Se3 particles were added continuously, leading to the formation of spiral-type nanoplates. At intermediate supersaturation, the aggregation of amorphous Bi2Se3 particles and subsequent recrystallization resulted in the formation of smooth nanoplates. Furthermore, at high supersaturation, polycrystalline Bi2Se3 cores formed initially, on which anisotropic growth of Bi2Se3 occurred. This work not only advances our understanding of the growth mechanism but also offers a new approach to control the morphology of Bi2Se3 nanostructures.

关键词： shape control Bi2Se3 nanostructures supersaturation mechanism study

哈尔滨市推进数字化政务服务发展的问题及对策研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

哈尔滨市推进数字化政务服务发展的问题及对策研究

作者： wang youcheng 哈尔滨商业大学

学位级别：硕士

随着现代计算机、区块链等新型互联网和数字通讯技术的快速发展,并逐渐与人民的日常生活融合在一起,使得在政府部门中的数字化的建设和发展得到了越来越多的关注。建立数字政府是推动国家治理体系和治理能力发展进步的重要举措。目前,... 详细信息

随着现代计算机、区块链等新型互联网和数字通讯技术的快速发展,并逐渐与人民的日常生活融合在一起,使得在政府部门中的数字化的建设和发展得到了越来越多的关注。建立数字政府是推动国家治理体系和治理能力发展进步的重要举措。目前,在我国大力推动以数字为核心的信息化过程中,政务服务的数字化发展也日益引起人们的重视。数字化政务服务是提高政府工作效能,建设服务型政府,提高社会满意度的关键环节。党的十九届五中全会提出,要将信息化革命、数字技术和政务相结合,大力推进现代化科技的广泛应用,做到“以数带政,以数带事”,使政府职能由被动到主动的转变。在2021年颁布实施的《黑龙江省省级政务云管理暂行办法》提出要从“群众跑路”转向“数据跑路”,逐渐消除“数据烟囱”与“信息孤岛”,促进各级政府部门之间的互联互通与业务协同发展,从而为哈尔滨市的“数字化政务服务”的构建起到一定的指引作用。哈尔滨市政府在2021年度出台《哈尔滨市“一网通办”向基层延伸工作方案》,从政务服务流程、政务服务项目规范化、政务服务质量三个方面入手,要把政务服务的“最后一公里”贯通,持续提升城市的治理和公共服务水平,把服务型的政府打造得更好。围绕哈尔滨市数字化政务服务发展中存在的问题和解决对策,运用新公共服务理论、流程再造理论、无缝隙政府理论和整体治理理论,运用调查研究法、文献研究法和对比研究法等方法,剖析哈尔滨市数字化政务服务发展中存在的公众参与度低、政务数据资源难以应用共享、政务信息安全隐患、专业数字人才匮乏等问题,并从忽略社会公众需求、部门存在信息壁垒、专业信息安全监管体系不健全、人才引进和绩效评价体系不完善等方面进行原因剖析。通过对比国外和国外政务服务的发展经验,找到了其中的成功因素,并针对目前哈尔滨市数字化政务服务发展中所面临的问题,有针对性地提出提升数字化政务服务水平,强化数字化政务服务数据共享应用,完善数字政府政务信息安全保障体系,重视人才队伍的培训和建设的应对措施。

关键词：政务服务数字化政务平台

Dynamics and vibration reduction performance of asymmetric tristable nonlinear energy sink

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2024年第3期45卷 389-406页

作者： Hongyan CHEN youcheng ZENG Hu DING Siukai LAI Liqun CHEN School of Mechanical Engineering University of Science and Technology BeijingBeijing 100083China Shanghai Key Laboratory of Mechanics in Energy Engineering Shanghai Frontier Science Center of MechanoinformaticsShanghai Institute of Applied Mathematics and MechanicsSchool of Mechanics and Engineering ScienceShanghai UniversityShanghai 200444China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityKowloonHong KongChina

With its complex nonlinear dynamic behavior,the tristable system has shown excellent performance in areas such as energy harvesting and vibration suppression,and has attracted a lot of *** this paper,an asymmetric tristable design is proposed to improve the vibration suppression efficiency of nonlinear energy sinks(NESs)for the first *** proposed asymmetric tristable NES(ATNES)is composed of a pair of oblique springs and a vertical ***,the three stable states,symmetric and asymmetric,can be achieved by the adjustment of the distance and stiffness asymmetry of the oblique *** governing equations of a linear oscillator(LO)coupled with the ATNES are *** approximate analytical solution to the coupled system is obtained by the harmonic balance method(HBM)and verified *** vibration suppression efficiency of three types of ATNES is *** results show that the asymmetric design can improve the efficiency of vibration reduction through comparing the chaotic motion of the NES oscillator between asymmetric steady *** addition,compared with the symmetrical tristable NES(TNES),the ATNES can effectively control smaller structural *** other words,the ATNES can effectively solve the threshold problem of TNES failure to weak ***,this paper reveals the vibration reduction mechanism of the ATNES,and provides a pathway to expand the effective excitation amplitude range of the NES.

关键词： asymmetric nonlinear energy sink(NES) tristable vibration control po-tential barrier