检索结果-南通市图书馆

Pharmacodynamic Mechanism of Kuanxiong Aerosol for Vasodilation and Improvement of Myocardial Ischemia

Chinese Journal of Integrative Medicine 2022年第4期28卷 319-329页

作者： LU Yan YANG Mei-ling SHEN A-ling LIN Shan PENG Mei-zhong wang Tian-yi LU Zhu-qing wang yi-lian PENG Jun CHU Jian-feng Academy of Integrative Medicine Fujian University of Traditional Chinese MedicineFuzhou350122China Chen Keji Academic Thought Inheritance Studio Fujian University of Traditional Chinese MedicineFuzhou350122China Fujian Key Laboratory of Integrative Medicine on Geriatrics Fujian University of Traditional Chinese MedicineFuzhou350122China Department of Acupuncture and Moxibustion Third People’s Hospital Affiliated to Fujian University of Traditional Chinese MedicineFuzhou350122China

Objective: To explore the effect of Kuanxiong Aerosol(KXA)on isoproterenol(ISO)-induced myocardial injury in rat ***: Totally 24 rats were radomly divided into control,ISO,KXA low-dose and high-dose groups according to the randomized block design method,and were administered by intragastric administration for 10 consecutive days,and on the 9th and 10th days,rats were injected with ISO for 2 consecutive days to construct an acute myocardial ischemia model to evaluate the improvement of myocardial ischemia by *** addition,the diastolic effect of KXA on rat thoracic aorta and its regulation of ion channels were tested by in vitro vascular tension *** influence of KXA on the expression of calcium-CaM-dependent protein kinase Ⅱ(CaMK Ⅱ)/extracellular regulated protein kinases(ERK)signaling pathway has also been ***: KXA significantly reduced the ISO-induced increase in ST-segment,interventricular septal thickness,cardiac mass index and cardiac tissue pathological changes in ***,the relaxation of isolated thoracic arterial rings that had been precontracted using norepinephrine(NE)or potassium chloride(KCl)was increased after KXA treatment in an endothelium-independent manner,and was attenuated by preincubation with verapamil,but not with tetraethylammonium chloride,4-aminopyridine,glibenclamide,or barium *** pretreatment attenuated vasoconstriction induced by CaCl_(2)in Ca^(2+)-free solutions containing K^(+) or *** addition,KXA pretreatment inhibited accumulation of Ca^(2+)in A7r5 cells mediated by KCl and NE and significantly decreased p-CaMK Ⅱ and p-ERK ***: KXA may inhibit influx and release of calcium and activate the CaMK Ⅱ/ERK signaling pathway to produce vasodilatory effects,thereby improving myocardial injury.

关键词： Kuanxiong Aerosol myocardial ischemia vasodilation Ca^(2+) CaMKⅡ/ERK pathway

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Malicious Document Detection Based on GGE Visualization

引用

Computers, Materials & Continua 2025年第1期82卷 1233-1254页

作者： Youhe wang yi Sun Yujie Li Chuanqi Zhou Henan Province Key Laboratory of Information Security Information Engineering UniversityZhengzhou450000China

With the development of anti-virus technology,malicious documents have gradually become the main pathway of Advanced Persistent Threat(APT)attacks,therefore,the development of effective malicious document classifiers has become particularly ***,detection methods based on document structure and behavioral features encounter challenges in feature engineering,these methods not only have limited accuracy,but also consume large resources,and usually can only detect documents in specific formats,which lacks versatility and *** address such problems,this paper proposes a novel malicious document detection method-visualizing documents as GGE images(Grayscale,Grayscale matrix,Entropy).The GGE method visualizes the original byte sequence of the malicious document as a grayscale image,the information entropy sequence of the document as an entropy image,and at the same time,the grayscale level co-occurrence matrix and the texture and spatial information stored in it are converted into grayscale matrix image,and fuses the three types of images to get the GGE color *** Convolutional Block Attention Module-EfficientNet-B0(CBAM-EfficientNet-B0)model is then used for classification,combining transfer learning and applying the pre-trained model on the ImageNet dataset to the feature extraction process of GGE *** shown in the experimental results,the GGE method has superior performance compared with other methods,which is suitable for detecting malicious documents in different formats,and achieves an accuracy of 99.44%and 97.39%on Portable Document Format(PDF)and office datasets,respectively,and consumes less time during the detection process,which can be effectively applied to the task of detecting malicious documents in real-time.

关键词： Malicious document visualization EfficientNet-B0 convolutional block attention module GGE image

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Multi-party quantum private comparison of size relationship based on one-direction quantum walks on a circle

引用

Science China(Information Sciences) 2025年

作者： Jintao wang Jiangyuan lian Tianyu YE College of Information & Electronic Engineering Zhejiang Gongshang University

Quantum walks (QW) are the quantum counterpart of classical random walks, and portray a natural stochastic process when the walker randomly wanders around. In a discretetime QW system on a circle, when the walker particle generally steps towards two directions, i.e., clockwise and anticlockwise, this kind of QW is called two-direction quantum walks on a circle (TDQWC); and the walker particle always steps towards one direction or stays stationary, this kind of QW is called as one-direction quantum walks on a circle (ODQWC).

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

High-temperature oxidation behavior and degradation mechanism of chromium-coated zirconium alloy cladding: a review

引用

Tungsten 2025年第1期7卷 50-70页

作者： yi Li Bei-Qi wang Xin-yin Zhang Shi-Jie wang Cong-yi Li Hui-Long Yang Ran-Ran Su Tong Liu School of Mechanical Engineering Shanghai Jiao Tong University College and Graduate School of Arts and Sciences University of Virginia Global Institute of Future Technology Shanghai Jiao Tong University

Accident-tolerant fuels(ATF) have been extensively studied to reduce the production rate and total amount of heat and hydrogen generated from high-temperature steam oxidation during severe ***-coated zirconium alloy cladding has become one of the most promising candidates for ATF because of its excellent corrosion and oxidation *** paper provides a comprehensive overview of the research progress on oxidation behaviors and degradation mechanisms in chromium-coated zirconium alloy cladding under high-temperature *** techniques to strengthen the oxidation resistance are highlighted and ***,challenges and opportunities for various future directions are addressed.

关键词： Accident-tolerant fuel Chromium coating Degradation mechanism High-temperature oxidation behavior Zirconium alloy cladding

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

纤维种类对C/C复合材料力学及摩擦磨损性能的影响

引用

新型炭材料 2020年第1期35卷 26-33页

作者：王连毅罗瑞盈商海东崔光远北京航空航天大学物理学院北京100191

为了制备性能优异、成本低廉的炭/炭(C/C)复合材料,以聚丙烯腈(PAN)基炭纤维预氧丝纤维(OPF)和炭纤维(CF)为原料,采用化学气相渗积致密化工艺,制备出两种密度均为1.7 g/cm^3左右的C/C复合材料,研究了不同种类纤维C/C复合材料的力学性能... 详细信息

为了制备性能优异、成本低廉的炭/炭(C/C)复合材料,以聚丙烯腈(PAN)基炭纤维预氧丝纤维(OPF)和炭纤维(CF)为原料,采用化学气相渗积致密化工艺,制备出两种密度均为1.7 g/cm^3左右的C/C复合材料,研究了不同种类纤维C/C复合材料的力学性能及不同刹车条件下的摩擦磨损性能,并观察其微观结构,分析纤维种类对摩擦磨损性能的影响机制。结果表明:两种C/C复合材料弯曲性能均表现出假塑性断裂,且弯曲强度相近,弯曲强度分别为127 MPa(CF C/C复合材料)、113 MPa(OPF C/C复合材料);OPF C/C复合材料的层间剪切强度为13.4 MPa,较CF C/C复合材料的层间剪切强度(10.01 MPa)提高了30.26%;与炭纤维相比,采用预氧丝作为原材料更易获得粗糙层热解炭,并且预氧丝纤维的硬度较低,易磨合形成光滑的摩擦面,在不同的刹车条件下,以预氧丝为原料制备的C/C复合材料具有更稳定的摩擦系数和更低的线性磨损;当刹车压力为0.65 MPa,刹车速度为20~25 m/s时,OPF C/C复合材料的摩擦系数稳定在0.35附近,同时表现出良好的抗磨损性能,线性磨损为1.3~1.5μm/(面·次)。

关键词：纤维种类 CVI C/C 弯曲强度摩擦磨损性能

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The detection, extraction and parameter estimation of extreme-mass-ratio inspirals with deep learning

引用

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 86-96页

作者： Qianyun Yun Wen-Biao Han yi-Yang Guo He wang Minghui Du Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences Shanghai Astronomical Observatory Chinese Academy of Sciences School of Physics and Astronomy Shanghai Jiao Tong University School of Astronomy and Space Science University of Chinese Academy of Sciences Taiji Laboratory for Gravitational Wave Universe (Beijing/Hangzhou) University of Chinese Academy of Sciences Lanzhou Center for Theoretical Physics Key Laboratory of Theoretical Physics of Gansu Province Key Laboratory of Quantum Theory and Applications of MoE Lanzhou University Institute of Theoretical Physics & Research Center of Gravitation Lanzhou University International Centre for Theoretical Physics Asia-Pacific (ICTP-AP) University of Chinese Academy of Sciences (UCAS) Center for Gravitational Wave Experiment National Microgravity Laboratory Institute of Mechanics Chinese Academy of Sciences

One of the primary goals of space-borne gravitational wave detectors is to detect and analyze extreme-mass-ratio inspirals(EMRIs). This task is particularly challenging because EMRI signals are complex, lengthy, and faint. In this work, we introduce a2-layer convolutional neural network(CNN) approach to detect EMRI signals for space-borne detectors, achieving a true positive rate(TPR) of 96.9% at a 1% false positive rate(FPR) for signal-to-noise ratio(SNR) from 50 to 100. Especially, the key intrinsic parameters of EMRIs such as the mass, spin of the supermassive black hole(SMBH) and the initial eccentricity of the orbit can also be inferred directly by employing a neural network. The mass and spin of the SMBH can be determined at 99% and 92% respectively. This will greatly reduce the parameter spaces and computing cost for the following Bayesian parameter *** model also has a low dependency on the accuracy of the waveform model. This study underscores the potential of deep learning methods in EMRI data analysis, enabling the rapid detection of EMRI signals and efficient parameter estimation.

关键词： gravitational wave EMRIs deep-learing

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

原地栖息真菌Talaromyces flavus作用下不同粒径利蛇纹石的风化作用研究

引用

岩石矿物学杂志 2016年第5期35卷 885-892页

作者：孙晟王艺谭刘连文南京大学地球科学与工程学院表生地球化学教育部重点实验室江苏南京210046

主要研究了原地栖息真菌Talaromyces flavus作用下不同粒径的蛇纹石矿物粉末的风化作用。蛇纹石矿物粉末被筛分为不同粒度的4组（150-300、100-150、75-100和45-75μm）后进行真菌溶蚀实验,并使用p H计、ICP-OES、FTIR、XRD、SEM对反应... 详细信息

主要研究了原地栖息真菌Talaromyces flavus作用下不同粒径的蛇纹石矿物粉末的风化作用。蛇纹石矿物粉末被筛分为不同粒度的4组（150-300、100-150、75-100和45-75μm）后进行真菌溶蚀实验,并使用p H计、ICP-OES、FTIR、XRD、SEM对反应产物进行了分析。结果表明,真菌作用显著加快了蛇纹石矿物的溶蚀,当蛇纹石矿物粒度降低到100μm左右时,Mg的溶出率从21.56%明显增加到35.91%。该现象可能与矿物比表面积的增大以及生物物理作用的增强有关。在此基础上粒径进一步减小并未使Mg溶出率明显提高,因此该粒径可以作为真菌对蛇纹石溶解工业化应用的最优粒径。扫描电镜观察与矿物相分析表明,反应过程中真菌分化产生的菌丝与矿物紧密接触,破坏了矿物的晶体结构,导致矿物相的改变。该研究结果可为相关菌种在浸矿等工业领域上的应用提供参考依据。

关键词：蛇纹石生物风化 Talaromyces flavus 丝状真菌粒径

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Small modifications of endo-functionalized cavities lead to large changes in molecular interaction in water

引用

Science China Chemistry 2025年第1期68卷 369-376页

作者： Song-Meng wang Hao Nian Yan-Fang wang Li-Shuo Zheng Yu-Tao Zheng yi-Wei Dong Liping Huang Xiaoping wang Wei Jiang Liu-Pan Yang Department of Chemistry Southern University of Science and Technology School of Chemistry and Pharmaceutical Sciences State Key Laboratory for Chemistry and Molecular Engineering of Medicinal ResourcesGuangxi Normal University School of Pharmaceutical Science Hengyang Medical School University of South China

Studying molecular recognition in aqueous environments is crucial for understanding biological processes. Herein, we present a series of N-doped endo-functionalized anthracene-based cavities by introducing inward-directed pyridine units. The subtle modifications can significantly affect the binding properties of these receptors, which is similar to the mutations in biological systems. Combining theoretical calculations and molecular recognition experiments demonstrated that these “mutations” have an impact on the hydrophobicity and charge distribution of the hosts, consequently significantly influencing molecular *** is crucial for understanding the intricate mechanisms of molecular-level interactions in biological receptors.

关键词： host-guest interaction hydrophobic effect endo-functionalized cavity mutation pyridine

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

商务日语教学的现状及对策

引用

时代农机 2017年第5期44卷 222-223页

作者：汪涟漪辽宁政法职业学院辽宁沈阳110161

从我国最近几年的实际情况来看,高职学校中学习日语专业的学生动手操作能力和应用商务日语的能力都在逐渐下降。所以文章的主要内容就是分析我国目前高职学校中学生学习日语的实际情况,然后找出影响其效率的问题,根据问题找到相对应的... 详细信息

从我国最近几年的实际情况来看,高职学校中学习日语专业的学生动手操作能力和应用商务日语的能力都在逐渐下降。所以文章的主要内容就是分析我国目前高职学校中学生学习日语的实际情况,然后找出影响其效率的问题,根据问题找到相对应的解决方案,最终实现我国培养高素质人才的目标。

关键词：高职商务日语解决措施

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

高职生物教学中比喻的应用研究

引用

教育教学论坛 2017年第15期 107-108页

作者：汪义莲池州职业技术学院安徽池州247000

在教学过程中,经常会运用到比喻,在碰到比较难的知识点时,能够帮助学生有效的进行理解,帮助教学任务更加顺利的进行。生物学是一项比较难的学科,它有一些抽象的概念比较难以理解,这个时候我们就会借用比喻来把它的内容清晰化、简单化,... 详细信息

在教学过程中,经常会运用到比喻,在碰到比较难的知识点时,能够帮助学生有效的进行理解,帮助教学任务更加顺利的进行。生物学是一项比较难的学科,它有一些抽象的概念比较难以理解,这个时候我们就会借用比喻来把它的内容清晰化、简单化,使它生动、易懂。对于高职的教师来说,这是一种常用的教学方法,它能够帮助高职生更好的学习生物,因此要做好生物学中的比喻研究。

关键词：高职生物学教学方法比喻教学

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：