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Inverse Design of Electron Lens

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Journal of Systems Engineering and Electronics 2001年第1期12卷 49-52页

作者： Tu Yan & Zhong Xuefei Electronics research institute, southeast university, nanjing 210096, P. R. china Electronics research institute Southeast University Nanjing 210096 P. R. China

The inverse design of electron lens is realized by two different methods in this paper. One is damped least square method and the other is the artificial neural network method. Their merits and defects are discussed according to our calculation results in the paper. In the condition of selecting the learning samples properly, the artificial neural network has obvious advantages in the inverse design of electron lens. It is an effective method to solve the inverse design problem in the electron optic system.

关键词： Electron optics Least squares approximations Neural networks Numerical methods Optical design

Chinese expert consensus on refined diagnosis,treatment,and management of advanced primary liver cancer(2023 edition)

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镍基高温合金不完全动态再结晶组织对力学性能的影响及断裂机制

肝脏研究（英文） 2024年第2期8卷 61-71页

作者： Xiufeng Liu Feng Xia Yue Chen Huichuan Sun Zhengqiang Yang Bo Chen Ming Zhao Xinyu Bi Tao Peng Aizier Ainiwaer Zhiwen Luo Fusheng wang Yinying Lu National Clinical research Center for Infectious Diseases Society of Hepatology,Beijing Medical Association Translational Medicine Branch,china Association of Gerontology and Geriatrics Department of Medical Oncology Bayi Hospital Affiliated to Nanjing Chinese Medical University NanjingJiangsuChina Department of Hepatobiliary Surgery Southwest HospitalArmy Medical University ChongqingChina Senior Department of Hepatology The Fifth Medical Center of PLA General HospitalBeijingChina Department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalFudan UniversityShanghaiChina Department of Interventional Therapy National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Minimally Invasive Interventional Therapy Liver Cancer Study and Service GroupSun Yat-sen University Cancer CenterGuangzhouGuangdongChina Department of Hepatobiliary Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanningGuangxiChina Senior Department of Infectious Diseases The Fifth Medical Center of PLA General HospitalBeijingChina Comprehensive Liver Cancer Center The Fifth Medical Center of PLA General HospitalBeijingChina

Hepatocellular carcinoma(HCC),commonly known as primary liver cancer,is a major cause of malignant tumors and cancer-related deaths in china,accounting for approximately 85％of all cancer cases in the *** guidelines have been used to diagnose and treat liver ***,these guidelines provide a broad definition for classifying advanced liver cancer,with an emphasis on a singular approach,without considering treatment options for individual ***,it is necessary to establish a comprehensive and practical expert consensus,specifically for china,to enhance the diagnosis and treatment of HCC using the Delphi *** classification criteria were refined for Chinese patients with HCC,and the corresponding optimal treatment regimen recommendations were *** recommendations took into account various factors,including tumor characteristics,vascular tumor thrombus grade,distant metastasis,liver function status,portal hypertension,and the hepatitis B virus replication status of patients with primary HCC,along with treatment *** findings and rec-ommendations provide detailed,scientific,and reasonable individualized diagnosis and treatment strategies for clinicians.

关键词： Hepatocellular carcinoma (HCC) Targeted therapy Immunotherapy Refined diagnosis and treatment Expert consensus

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材料导报 2024年第6期38卷 217-221页

作者：王淼刘延辉刘昭昭陕西科技大学机电工程学院西安710021 西北工业大学材料科学与工程学院西安710072 浙江温州轻工研究院浙江温州325002

本工作对热等静压态镍基高温合金FGH4096在变形温度为1 080℃、应变速率为3 s^(-1)的条件下进行等温变形,最大变形量为50%,进而研究高温变形过程中该合金组织演变规律,并选取具有典型形变组织的区域在700℃、0.001 s^(-1)条件下进行力... 详细信息

本工作对热等静压态镍基高温合金FGH4096在变形温度为1 080℃、应变速率为3 s^(-1)的条件下进行等温变形,最大变形量为50%,进而研究高温变形过程中该合金组织演变规律,并选取具有典型形变组织的区域在700℃、0.001 s^(-1)条件下进行力学性能测试。基于光学显微镜(OM)、扫描电镜(SEM)和电子背散射衍射技术(EBSD)对显微组织和断口的分析测试结果,发现热变形过程中产生的不完全动态再结晶组织从试样截面中心到边缘区域再结晶程度依次降低,中心部位抗拉强度可达到1 422.79 MPa,屈服强度为1 110.3 MPa,延伸率为10.15%。再结晶晶粒形核首先发生在晶界处,形核方式主要为晶界凸出形核。不完全动态再结晶组织中的变形晶粒内部存在亚晶界,对位错的运动起到阻碍作用,使得合金强度提高。合金断口形貌为韧窝状和撕裂棱的混合结构,断裂方式为穿晶断裂。

关键词： FGH4096合金不完全动态再结晶力学性能断口分析

High mechanical strength Si anode synthesis with interlayer bonded expanded graphite structure for lithium-ion batteries

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Journal of Energy Chemistry 2024年第6期93卷 253-263,I0007页

作者： Wenhui Lai Jong Hak Lee Lu Shi Yuqing Liu yanhui Pu Yong Kang Ong Carlos Limpo Ting Xiong Yifan Rao Chorng Haur Sow Barbaros Ozyilmaz Department of Material Science&Engineering National University of SingaporeSingapore 117575Singapore Center for Advanced 2D Materials National University of SingaporeSingapore 117546Singapore Department of Physics National University of SingaporeSingapore 117551Singapore institute forFunctional Intelligent Materials National University of SingaporeSingapore 117544Singapore

Despite advancements in silicon-based anodes for high-capacity lithium-ion batteries,their widespread commercial adoption is still hindered by significant volume expansion during cycling,especially at high active mass loadings crucial for practical *** root of these challenges lies in the mechanical instability of the material,which subsequently leads to the structural failure of the ***,we present a novel synthesis of a composite combining expanded graphite and silicon *** composite features a unique interlayer-bonded graphite structure,achieved through the application of a modified spark plasma sintering ***,this innovative structure not only facilitates efficient ion and electron transport but also provides exceptional mechanical strength(Vickers hardness:up to658 MPa,Young's modulus:11.6 GPa).This strength effectively accommodates silicon expansion,resulting in an impressive areal capacity of 2.9 mA h cm^(-2)(736 mA h g^(-1)) and a steady cycle life(93% after 100cycles).Such outsta nding performance is paired with features appropriate for large-scale industrial production of silicon batteries,such as active mass loading of at least 3.9 mg cm^(-2),a high-tap density electrode material of 1.68 g cm^(-3)(secondary clusters:1.12 g cm^(-3)),and a production yield of up to 1 kg per day.

关键词： Lithium-ion battery Silicon anode Spark plasma sintering Interlayer bonding Mechanical strength Tap density

小浪底水库运行以来对黄河下游河道河床演变特性的影响

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水利学报 2024年第5期55卷 505-515页

作者：王远见王强刘彦晖刘刚江恩慧黄河水利科学研究院水利部黄河下游河道与河口治理重点实验室河南郑州450003 河南省湖库功能恢复与维持工程技术研究中心河南郑州450003

小浪底水库自1999年10月下闸蓄水,23年来深刻改变了进入黄河下游河道的径流泥沙过程,进而引起了下游河道的再造床。本研究以1960—2022年长序列水文泥沙、断面地形、遥感影像等多源资料为基础,从径流泥沙、冲淤演变、形态调整三个方面... 详细信息

小浪底水库自1999年10月下闸蓄水,23年来深刻改变了进入黄河下游河道的径流泥沙过程,进而引起了下游河道的再造床。本研究以1960—2022年长序列水文泥沙、断面地形、遥感影像等多源资料为基础,从径流泥沙、冲淤演变、形态调整三个方面阐明了小浪底水库运行以来对下游河道河床演变特性的影响。结果表明:(1)水库拦沙效果显著,下泄水量在年内分配更加均匀、沙量则向汛期更加集中;大流量和高含沙事件的严重程度和发生频率均有所降低;悬沙调整不明显,床沙粗化显著。(2)扭转了黄河下游河道持续淤积的趋势,冲淤调整主要发生在花园口至高村的游荡性河段;冲刷效率持续下降,主槽过流能力得到显著恢复。(3)游荡性河段横断面形态向窄深发展,二级悬河发育得到有效缓解,整体河势处于相对稳定状态。研究成果丰富了多沙河流修建水库对下游河道影响的科学认识,也可为小浪底水库优化调度提供科技支撑。

关键词：径流泥沙冲淤演变形态特征游荡性河段黄河下游

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research on the evaluation model of the modernization level of urban construction in Jiangsu Province,china

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Science china(Technological Sciences) 2010年第9期53卷 2510-2514页

作者： YANG JunYan1 & CHEN Wen2 1 School of architecture,southeast university,nanjing 210096,china 2 nanjing institute of Geography and Limnology,Chinese Academy of Sciences,nanjing 210008,china School of architecture Southeast University Nanjing China nanjing institute of Geography and Limnology Chinese Academy of Sciences Nanjing China

The modernization of urban construction is a key index in the process of urbanization,and also is an important index to measure the level of socio-economic and cultural *** paper analyzes and explores the related concepts of modernization of urban construction,analyzes the situation and identity of urban construction layer by layer so as to establish an evaluation index system of the modernization level of urban construction and then the paper evaluates the modernization level of urban construction from four different angles,which are the perspectives of the urban planning control,the level of urban facilities,urban management,urban construction *** later analyzes the evaluation results by choosing Jiangsu Province as a research hierarchy from the scale chains of urban study and makes efforts to the operative and directive development direction.

关键词： modernization of urban construction index system evaluation model

Reduced-order output feedback controllers for the robust H^(∞) performance problem

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Chinese Science Bulletin 1997年第6期42卷 517-522页

作者： GUO Lei, XIN Xin and FENG ChunboRescarch institute of Automation, southeast university, nanjing 210096, china research institute of Automation Southeast University Nanjing China

OVER the last decade, the H~∞ control has been recognized as one of the most effective tools for robust control. A lot of researches have been devoted to robust H~∞ problems for uncertain systems. Recently, Zhou et al., presented the notion of strongly robust H~∞ performance, which is an extension of quadratic stability and equivalent to robust H~∞ problem. However. only state-feedback controllers were discussed.

关键词： robust control H∞ control matrix inequality reduced-order controller.

Promotion effect of FOXCUT as a microRNA sponge for miR-24-3p on progression in triple-negative breast cancer through the p38 MAPK signaling pathway

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Chinese Medical Journal 2024年第1期137卷 105-114页

作者： Xiafei Yu Fangze Qian Xiaoqiang Zhang yanhui Zhu Gao He Junzhe Yang Xian Wu Yi Zhou Li Shen Xiaoyue Shi Hongfei Zhang Xiao’an Liu Department of Breast Surgery The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China

Background:Triple-negative breast cancer(TNBC)is a type of highly invasive breast cancer with a poor *** to new research,long noncoding RNAs(lncRNAs)play a significant role in the progression of *** the role of lncRNAs in breast cancer has been well reported,few studies have focused on *** study aimed to explore the biological function and clinical significance of forkhead box C1 promoter upstream transcript(FOXCUT)in triple-negative breast ***:Based on a bioinformatic analysis of the cancer genome atlas(TCGA)database,we detected that the lncRNA FOXCUT was overexpressed in TNBC tissues,which was further validated in an external cohort of tissues from the General Surgery Department of the First Affiliated Hospital of nanjing Medical *** functions of FOXCUT in proliferation,migration,and invasion were detected in vitro or in *** assays and RNA immunoprecipitation(RIP)were performed to reveal that FOXCUT acted as a competitive endogenous RNA(ceRNA)for the microRNA miR-24-3p and consequently inhibited the degradation of ***:lncRNA FOXCUT was markedly highly expressed in breast cancer,which was associated with poor prognosis in some *** of FOXCUT significantly inhibited cancer growth and metastasis in vitro or in ***,FOXCUT competitively bounded to miR-24-3p to prevent the degradation of p38,which might act as an oncogene in breast ***:Collectively,this research revealed a novel FOXCUT/miR-24-3p/p38 axis that affected breast cancer progression and suggested that the lncRNA FOXCUT could be a diagnostic marker and therapeutic target for breast cancer.

关键词： Triple negative breast neoplasms RNA,long noncoding FOXCUT miR-24-3p p38 MAPK signaling pathway Disease progression

Hydroxylated metal–organic-layer nanocages anchoring single atomic cobalt sites for robust photocatalytic CO_(2) reduction

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Nano research 2024年第4期17卷 2410-2419页

作者： Weiyi Pan Zhihe Wei yanhui Su Yuebin Lian Zhangyi Zheng Huihong Yuan Yongze Qin Xulan Xie Qianqian Bai Zhenyang Jiao Wei Hua Jinzhou Chen Wenjun Yang Zhao Deng Yang Peng Soochow institute for Energy and Materials Innovations College of EnergySoochow UniversitySuzhou 215006China Key Laboratory of Advanced Carbon Materials and Wearable Energy Technologies of Jiangsu Province Soochow UniversitySuzhou 215006China School of Photoelectric Engineering Changzhou institute of technologyChangzhou 213032China Jiangsu Key Laboratory for Advanced Negative Carbon Technologies Soochow UniversitySuzhou 215123China

Assembly of two-dimensional(2D)metal–organic layers(MOLs)based on the hard and soft acid–base theorem represents an exquisite strategy for the construction of photocatalytic platforms in virtue of the highly exposed active sites,much improved mass transport,and greatly elevated ***,nanocages composed of MOLs are produced for the first time through a cosolvent approach utilizing zirconium-based UiO-66-(OH)2 as the structural *** endow the catalytic activity for CO_(2) conversion,single atomic Co^(2+)sites are appended to the Zr-oxo nodes of the MOL cages,demonstrating a remarkable CO yield of 7.74 mmol·g^(-1)·h^(-1) and operational stability of 97.1%product retention after five repeated *** an outstanding photocatalytic performance is mainly attributed to the unique nanocage morphology comprising enormous 2D nanosheets for augmented Co^(2+)exposure and the abundant surface hydroxyl groups for local CO_(2) *** work underlines the tailoring of both metal–organic framework(MOF)morphology and functionality to boost the turnover rate of photocatalytic CO_(2) reduction reaction(CO_(2)RR).

关键词： photocatalytic CO_(2) reduction metal–organic layer nanocage single-atom catalyst co-catalyst