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现代城市研究 2011年第12期26卷 67-72页

作者：王先鹏赵艳莉鲍维科宁波市城乡规划研究中心

目前城市综合体成为国内各大城市建设的热点,但存在概念内涵泛化和缺乏科学布局引导的弊端。本文以宁波市为个案,力求廓清城市综合体的内涵与特征,深入剖析总结其发展规律,并提出空间发展布局的建议,以期为同类城市城市综合体的有序发... 详细信息

目前城市综合体成为国内各大城市建设的热点,但存在概念内涵泛化和缺乏科学布局引导的弊端。本文以宁波市为个案,力求廓清城市综合体的内涵与特征,深入剖析总结其发展规律,并提出空间发展布局的建议,以期为同类城市城市综合体的有序发展提供借鉴和参考。

关键词：宁波城市综合体内涵发展规律

关于高校地质学基础课程多媒体教学如何适应考试科学化管理的思考

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中国地质教育 2008年第1期17卷 89-92页

作者：杜国云王鹏贤鲁东大学地理与规划学院山东烟台264025 烟台大学人文学院山东烟台264005

教学过程与考试是教学活动的两个基本环节。在"教"、"考"分离的未来发展形势下,以及考试科学化管理实施的过程中,教学计划及教学内容、教学目标的实施必须与命题相统一,才能很好地完成教学任务。多媒体教学手段的运用有其有利的一面,但... 详细信息

教学过程与考试是教学活动的两个基本环节。在"教"、"考"分离的未来发展形势下,以及考试科学化管理实施的过程中,教学计划及教学内容、教学目标的实施必须与命题相统一,才能很好地完成教学任务。多媒体教学手段的运用有其有利的一面,但与传统的教学方法和手段相比也存在一定的局限与不足,需要进行深入的教学研究才能够加以解决。课程教学中,在制订教学计划的同时,应制定"命题双向细目表",将"教"与"考"有机地结合起来。

关键词：地质学基础多媒体教学考试科学化管理命题双向细目表

外加Fe2+协同硝酸盐型铁氧化菌对低碳氮比废水反硝化影响研究

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工业用水与废水 2019年第3期50卷 12-16页

作者：王先鹏黄显怀安徽建筑大学环境与能源工程学院合肥230601 安徽建筑大学水污染控制与废水资源化安徽省重点实验室合肥230601

针对废水处理过程中反硝化阶段碳源不足需要外加有机物的情况,通过驯化培养以Fe^2+为电子供体的硝酸盐型厌氧铁氧化菌(NAIOM),接种至普通反硝化污泥中(ASBR反应器),研究了NAIOM污泥及外加Fe^2+对反硝化脱氮效果的提升。结果表明:反应器... 详细信息

针对废水处理过程中反硝化阶段碳源不足需要外加有机物的情况,通过驯化培养以Fe^2+为电子供体的硝酸盐型厌氧铁氧化菌(NAIOM),接种至普通反硝化污泥中(ASBR反应器),研究了NAIOM污泥及外加Fe^2+对反硝化脱氮效果的提升。结果表明:反应器在接种NAIOM污泥和投加Fe^2+后,碳氮比较高时NO3^--N去除率变化不大,随着碳氮比的不断降低NO3^--N去除率提升逐渐明显,在碳氮比为3.42、2.28、1.71时分别为90.20%、85.12%、78.86%,较普通反硝化污泥不投加Fe^2+时的NO3^--N去除率分别提升了17.80%、24.59%、28.70%,接种NAIOM污泥协同外加Fe^2+对提高低碳氮比废水的NO3^--N去除率效果显著。

关键词：反硝化脱氮外加Fe^2+ 硝酸盐型厌氧铁氧化菌 ASBR反应器

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基于集成学习的连退带钢质量在线预报方法

控制工程 2017年第3期24卷 481-486页

作者：王显鹏黄灿明徐子睿王丹敬东北大学工业与系统工程研究所沈阳110819

钢铁企业连续退火生产过程由于工艺复杂并且包含众多相互影响的过程变量,导致带钢产品质量波动较大,难以进行在线测量。针对该问题,提出了一种基于混合集成学习的带钢产品质量在线预报方法。该方法以Bagging为基础,引入了Adaboost中对... 详细信息

钢铁企业连续退火生产过程由于工艺复杂并且包含众多相互影响的过程变量,导致带钢产品质量波动较大,难以进行在线测量。针对该问题,提出了一种基于混合集成学习的带钢产品质量在线预报方法。该方法以Bagging为基础,引入了Adaboost中对误差较大样本的重点学习策略,以提高混合集成学习模型的精度并改进泛化能力;在子学习机的训练中提出了基于动态加权的最小二乘支持向量机方法,以改进子学习机的鲁棒性。基于实际连退生产过程数据的测试结果表明,所提出的混合集成学习方法在预测精度和泛化能力上均要优于Bagging和Adaboost等传统的集成学习建模方法。

关键词：连续退火质量在线预报集成学习最小二乘支持向量机

Effect of order–disorder transition on thermodynamic and electronic properties of σ and χ phases in W–Re alloy: the first-principles calculation

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Tungsten 2025年第1期7卷 195-213页

作者： Zhi-peng Zhu Dian Jia William Yi wang Jun-Lei Yin Xing-Yu Gao Shu-Feng Yang Hai-Feng Song Jin-Shan Li State Key Laboratory of Solidification Processing Northwestern Polytechnical University Laboratory of Computational Physics Institute of Applied Physics and Computational Mathematics School of Metallurgical and Ecological Engineering University of Science and Technology Beijing

The Tungsten-Rhenium(W-Re) alloys,celebrated for their high melting point,strength at elevated temperatures,electrical resistivity,and radiation resistance,have been widely utilized in high-temperature components,aerospace,electronics,and nuclear *** constituents of the topologically close-packed(TCP) phases,the sigma phase(σ) and chi phase(χ) formed within W-Re alloys wield considerable influence on the mechanical properties and the stability of the *** calculations were utilized in the present work to explore the structural,thermodynamic,and electronic properties of both ordered and disordered configurations within the σ and χ phases,culminating in a systematic elucidation of the higher phase stability exhibited by the ordered *** is found that the bulk modulus of these two phases is directly proportional to the concentration of Re in the alloy,while the equilibrium volume is inversely *** thermodynamic parameters of the σ and χ phases are calculated via the mean-field potential *** similar trends observed in the isobaric heat capacity,enthalpy increment,and entropy change curves for these two phases suggest they possess comparable thermodynamic *** is noteworthy that the contribution of ionic vibrations predominantly affects the isobaric heat capacity,while the contribution of thermal electronic excitations increases linearly with *** the structure and thermodynamic properties of TCP phases in W-Re alloys at low temperatures has profound significance for optimizing material performance,microstructures features,establishing theoretical foundations,and predicting material behavior.

关键词： First-principles calculations Phase stability TCP phases Thermodynamic properties W–Re alloy

Utilizing engineered extracellular vesicles as delivery vectors in the management of ischemic stroke:a special outlook on mitochondrial delivery

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Neural Regeneration Research 2025年第8期20卷 2181-2198页

作者： Jiali Chen Yiyang Li Xingping Quan Jinfen Chen Yan Han Li Yang Manfei Zhou Greta Seng peng Mok Ruibing wang Yonghua Zhao Institute of Chinese Medical Sciences State Key Laboratory of Quality Research in Chinese MedicineUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Pharmacy Hunan Provincial People’s Hospitalthe First Affiliated Hospital of Hunan Normal UniversityChangshaHunan ProvinceChina Department of Electrical and Computer Engineering University of MacaoTaipaMacao Special Administrative RegionChina Department of Pharmaceutical Sciences Faculty of Health SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina

Ischemic stroke is a secondary cause of mortality worldwide,imposing considerable medical and economic burdens on *** vesicles,serving as natural nanocarriers for drug delivery,exhibit excellent biocompatibility in vivo and have significant advantages in the management of ischemic ***,the uncertain distribution and rapid clearance of extracellular vesicles impede their delivery *** utilizing membrane decoration or by encapsulating therapeutic cargo within extracellular vesicles,their delivery efficacy may be greatly ***,previous studies have indicated that microvesicles,a subset of large-sized extracellular vesicles,can transport mitochondria to neighboring cells,thereby aiding in the restoration of mitochondrial function post-ischemic *** extracellular vesicles have also demonstrated the capability to transfer mitochondrial components,such as proteins or deoxyribonucleic acid,or their sub-components,for extracellular vesicle-based ischemic stroke *** this review,we undertake a comparative analysis of the isolation techniques employed for extracellular vesicles and present an overview of the current dominant extracellular vesicle modification *** the complex facets of treating ischemic stroke,we also delineate various extracellular vesicle modification approaches which are suited to different facets of the treatment ***,given the burgeoning interest in mitochondrial delivery,we delved into the feasibility and existing research findings on the transportation of mitochondrial fractions or intact mitochondria through small extracellular vesicles and microvesicles to offer a fresh perspective on ischemic stroke therapy.

关键词： delivery engineering extracellular vesicles identification ischemic stroke isolation mitochondria targeting strategy therapeutic effects

冠状动脉旁路移植术治疗老年无保护左主干冠状动脉病变的临床分析

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中国危重病急救医学 2011年第12期23卷 709-713页

作者：潘昱陈方罗亚玮玉献鹏张晓玲何继强首都医科大学附属北京安贞医院 100029

目的分析老年无保护左主干冠状动脉（冠脉）病变（ULMCA）患者行冠脉旁路移植术（CABG）的临床特点及预后。方法选择经CABG治疗的ULMCA患者176例，根据年龄分为老年组（≥65岁，83例）和非老年组（〈65岁，93例）。比较分析两组患者的... 详细信息

目的分析老年无保护左主干冠状动脉（冠脉）病变（ULMCA）患者行冠脉旁路移植术（CABG）的临床特点及预后。方法选择经CABG治疗的ULMCA患者176例，根据年龄分为老年组（≥65岁，83例）和非老年组（〈65岁，93例）。比较分析两组患者的临床特点、冠脉病变及远期临床预后。结果老年组高密度脂蛋白胆固醇（mmol／L）明显高于非老年组（28．36±17．20比13．68±7．78，P〈0．01），低密度脂蛋白胆固醇（mmol／L）显著低于非老年组（1．21±0．77比2．48±1．27，P〈0．01）。老年组左主干病变平均狭窄程度高于非老年组[（94．56±8．01）％比（87．96±11．10Vo），P〈0．013，合并多支病变（75．9％比58．1％，P〈0．05）及慢性完全闭塞病变（55．4％比29．0％，P〈0．05）多见。老年组和非老年组远期随访患者心脑血管事件（MACCE）、脑血管事件、心肌梗死、心源性死亡、总死亡事件发生率差异均无统计学意义（16．9％比17．2％，3．6％比3．2％，3．6％比5．4％，6．0％比9．7％，12．0％比8．6％，均P〉0．05）。结论老年ULMCA患者病情相对复杂，对于65岁以上者CABG可行，并且远期临床转归较为满意。

关键词：无保护左主干冠状动脉病变冠状动脉旁路移植术老年

Atmospheric reductive catalytic fractionation of lignocellulose integrated with one-pot catalytic conversion of carbohydrate yielding valuable lignin monomers and platform chemicals from corn straw

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Green Energy & Environment 2025年第1期10卷 161-172页

作者： Meng-Ying Liu Zhe-Hui Zhang Xue-Qi wang Qian Sun Chen Zhang Yu Li Zhuohua Sun Katalin Barta Feng peng Tong-Qi Yuan State Key Laboratory of Efficient Production of Forest Resources Beijing Forestry UniversityBeijing100083China Beijing Key Laboratory of Lignocellulosic Chemistry Beijing Forestry UniversityBeijing100083China Department of Chemistry Organic and Bioorganic ChemistryUniversity of GrazHeinrichstrasse 28/II8010 GrazAustria

Developing a cost-effective and environmentally friendly process for the production of valuable chemicals from abundant herbal biomass receives great attentions in recent ***,taking advantage of the“lignin first”strategy,corn straw is converted to valuable chemicals including lignin monomers,furfural and 5-methoxymethylfurfural via a two steps *** key of this research lies in the development of a green and low-cost catalytic process utilizing magnetic Raney Ni catalyst and high boiling point ethylene *** utilization of neat ethylene glycol as the sole slovent under atmospheric conditions obviates the need for additional additives,thereby facilitating the entire process to be conducted in glass flasks and rendering it highly convenient for scaling *** the initial step,depolymerization of corn straw lignin resulted in a monomer yield of 18.1 wt%.Subsequently,in a dimethyl carbonate system,the carbohydrate component underwent complete conversion in a one-pot process,yielding furfural and 5-methoxymethylfurfural as the primary products with an impressive yield of 47.7%.

关键词： Atmospheric reductive catalytic fractionation Corn straw Ethylene glycol Raney Ni 5-Methoxymethylfurfural

Multiphysics simulation and optimization of the in-situ beneficiation process of ilmenite minerals from lunar regolith

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Science China Earth Sciences 2025年第1期68卷 195-207页

作者： peng ZHANG Xin LIU Guanghui LIU Wei DAI Hanzhe YANG Haibo ZHENG Zhi wang Ran NIU Yifan BAI Yang ZHANG Chengbao LIU Ge YANG Junwei YANG Guang ZHANG Technology and Engineering Center for Space Utilization Chinese Academy of Sciences Beijing Hegong Simulation Co. Ltd

The exploration and utilization of lunar resources have become the major objectives of future lunar exploration missions. The classified collection and processing of lunar minerals is the basic prerequisite for the in-situ exploration and utilization of lunar resources. In this study, we propose a scheme for in-situ separation of magnetic minerals from lunar soils using the dry magnetic separation method. The scheme can realize the purpose of separating magnetic minerals from lunar regolith by altering the motion trajectory of lunar regolith particles with different magnetic properties. Detailed modeling of the dry magnetic separation device is conducted, and the three-dimensional distribution of magnetic parameters is calculated and analyzed. Based on the characterization and analysis of the Chang E-5's samples, the morphologies and physical parameters of lunar regolith particles are modeled and simulated. A discrete element simulation of the motion process of lunar regolith particles under multi-physical field conditions is performed, and the influences of key parameters on the beneficiation performance of lunar magnetic minerals are investigated. Our results indicate that optimal separation and beneficiation of lunar regolith particles can be achieved under specific conditions of magnetic field strength and drum speed. Additionally, we analyze the effects of lunar weak gravity conditions and the charged nature of lunar particles on the beneficiation process, showing that these factors can obviously enhance the beneficiation process of lunar ilmenites. This study demonstrates the feasibility of using the dry magnetic separation method for the beneficiation of magnetic minerals from lunar regolith, providing a theoretical basis for the scientific tasks of collecting, processing, and utilizing lunar mineral resources.

关键词： Lunar regolith In-situ resource utilization Magnetic separation Classified sampling

复方七叶皂苷(128例)与双氯芬酸(101例)治疗急性软组织挫伤的比较

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中国新药与临床杂志 2004年第7期23卷 395-397页

作者：林向华胡文贤王鹏王志国青岛海慈医疗集团药学部山东青岛266033

目的 :观察复方七叶皂苷凝胶治疗急性软组织挫伤的疗效 ,并与双氯芬酸凝胶比较。方法 :2 2 9例急性软组织挫伤病人 ,男性 16 9例 ,女性 6 0例 ,年龄 (32±s 14 )a ,14～ 72a ,分成 2组。治疗组12 8例 ,于受伤部位涂抹复方七叶皂苷凝胶 ,... 详细信息

目的 :观察复方七叶皂苷凝胶治疗急性软组织挫伤的疗效 ,并与双氯芬酸凝胶比较。方法 :2 2 9例急性软组织挫伤病人 ,男性 16 9例 ,女性 6 0例 ,年龄 (32±s 14 )a ,14～ 72a ,分成 2组。治疗组12 8例 ,于受伤部位涂抹复方七叶皂苷凝胶 ,bid ;对照组 10 1例 ,于受伤部位涂抹双氯芬酸凝胶 ,bid。 2组疗程均为 7d ,分别观察 2组病人用药前后疼痛、肿胀、红热、功能障碍等症状体征。结果 :治疗组显效率 81.2 % (10 4 / 12 8) ,总有效率 93.0 % (119/12 8) ,对照组显效率 9.9% (10 / 10 1) ,总有效率82 .2 % (83/ 10 1)。 2组疗效差异有非常显著意义(P <0 .0 1)。结论 :复方七叶皂苷凝胶外用治疗急性软组织挫伤疗效显著 ,优于双氯芬酸凝胶。

关键词：七叶素挫伤软组织损伤双氯芬酸复方七叶皂苷凝胶