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Noise Effects on Oscillator Network of Transcription Regulators

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Communications in Theoretical Physics 2002年第10期38卷 497-502页

作者： wang xian-ju ai bao-quan liu Guo-Tao liu liang-gang Department of Physics Zhongshan University Guangzhou 510275 China Department of Physics Zhongshan University Guangzhou 510275 China Department of Physics Zhongshan University Guangzhou 510275 China Department of Physics Zhongshan University Guangzhou 510275 China

Based on the model describing the regulation of the PRM operator region of λ phage proposed by Jeff Hastyet al., we study the noise effects on the oscillator network. We find that the additive noise cannot change the period andthe amplitude of the relaxation oscillator, but in the multiplicative case, the period of the relaxation oscillator increasesto a constant value with the increase of the strength of noise, and the amplitude of the relaxation oscillator also showsincreases with the increase of the strength of noise. This novel results suggest that an external multiplicative noise sourcecould be used to control gene expression.

关键词： gene control, noise strength, oscillator

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分子马达模型综述(英文)

中山大学学报（自然科学版） 2001年第2期40卷 42-44页

作者：王先菊艾保全刘良钢中山大学物理学系广东广州510275

介绍三类马达酶的结构 ,功能和生命体内分子马达的研究状况 ,并详细介绍几类典型分子马达的理论模型。

关键词：分子马达模型肌肉运动研究现状综述马达酶结构

Bevacizumab as adjuvant therapy in the management of pterygium: a systematic review and Meta-analysis

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International Journal of Ophthalmology(English edition) 2017年第7期10卷 1126-1133页

作者： Jian liu Jie-Hui Xu Wen Xu Guan-Lu liang Ji-xian Lou Yi wang Ji-quan Wen Yong-bao Cao Department of Ophthalmology Zhejiang Hospital Eye Center the Second Affiliated Hospital of Zhejiang UniversityCollege of Medicine

aiM： To evaluate the clinical effect of bevacizumab in pterygium ***： A systematic review and quantitative Metaanalysis was performed. Pub Med, EMBASE, Web of Science and Cochrane database were searched for eligible literatures published in English until june 2016. The endpoint was recurrence rate and pooled risk ratio（RR） was ***： Nine eligible studies were included and Metaanalysis results showed no significantly difference in patients treated with bevacizumab in short term followup [3mo： RR=0.70（0.34, 1.45）; 6mo： RR=0.55（0.23, 1.32）] compared with control groups. No significant effects were observed in favor of bevacizumab in subgroup analyses： patients with subconjunctival injection of bevacizumab [3mo： RR=0.95（0.70, 1.29）; 6mo： RR=0.83（0.55, 1.28）], primary pterygium [3mo： RR=0.59（0.23, 1.54; 6mo： RR=0.59（0.23, 1.53）], simple pterygium excision [3mo： 0.32（0.05, 2.04）, P=0.23; 6mo： 0.27（0.05, 1.53）] and excision with conjunctival autograft [3mo： 1.51（0.25, 9.15）; 6mo： 1.11（0.06, 21.69）].CONCLUSION： In this Meta-analysis, we did not found the significant effect of bevacizumab in pterygium treatment, at least in short term follow-up（3mo and 6mo）.

关键词： pterygium bevacizumab therapy recurrence Meta-analysis

Anemia and risk of periprocedural cerebral injury detected by diffusion-weighted magnetic resonance imaging in patients undergoing transcatheter aortic valve replacement

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World Journal of Emergency Medicine 2022年第1期13卷 32-39页

作者： Stella Ng Qi-feng Zhu ju-bo Jiang Chun-hui liu Jia-qi Fan Ye-ming Xu xian-bao liu Jian-an wang Department of Cardiology the Second Affi liated Hospital of Zhejiang University School of MedicineHangzhou 310009China Zhejiang University School of Medicine Hangzhou 310058China

BACKGROUND: Anemia is prevalent in patients undergoing transcatheter aortic valve replacement(TAVR) and has been linked to impaired outcomes after the procedure. Few studies have evaluated the impact of anemia and new ischemic lesions post ***: We prospectively enrolled 158 patients who received TAVR in our center. Anemia was defined according to the World Health Organization criteria as hemoglobin ains to be investigated.

关键词： Aortic stenosis Anemia Cerebral ischemic lesions Transcatheter aortic valve replacement

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狭窄程度对锥缩血管中脉动流的影响(英文)

计算物理 2005年第4期22卷 351-357页

作者：刘国涛王先菊艾保全刘良钢中山大学物理系广东广州510275

建立了一个轴对称的狭窄锥缩刚性动脉模型.利用不可压缩的N-S方程作为计算的理论基础,采用有限差分方案进行数值分析.提供了3种狭窄程度下的管壁切应力分布曲线并进行了分析和比较,同时给出了模型M3(h R0=1 3)在一个流动周期内的流线图... 详细信息

建立了一个轴对称的狭窄锥缩刚性动脉模型.利用不可压缩的N-S方程作为计算的理论基础,采用有限差分方案进行数值分析.提供了3种狭窄程度下的管壁切应力分布曲线并进行了分析和比较,同时给出了模型M3(h R0=1 3)在一个流动周期内的流线图.结果显示狭窄附近的流场受到了干扰,特别是狭窄的喉部及其下游区域的流场,并且狭窄程度越严重,狭窄对流场的影响就越大.

关键词：脉动流管壁切应力狭窄锥缩动脉数值分析

A Resonantly Pumped Q-Switched Er:Lu_(2)SiO_(5) Laser

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Chinese Physics Letters 2013年第3期30卷 81-83页

作者： YAO bao-quan YU Xiao liu Xiao-Lei DUAN Xiao-Ming ju You-Lun wang Yue-Zhu National Key Laboratory of Tunable Laser Technology Harbin Institute of TechnologyHarbin 150001

We describe the cw and Q-switched actions of a novel erbium-doped crystal Er:Lu_(2)SiO_(5) pumped by a MgO:PPLN-OPO at 1536 *** efficient 1580.9 nm cw laser with the output power of 608 mW is obtained when the incident power is 4.5 W,corresponding to a slope efficiency of 11.1%.In the Q-switched operation,the pulse energy up to 1.2 mJ is obtained at a repetition rate of 200 Hz.

关键词： switched pumped OPO

Prevention of pancreaticojejunal anastomotic leakage after pancreaticoduodenectomy with separate internal drainage of bile and pancreatic fluid

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Hepatobiliary & Pancreatic Diseases International 2003年第1期2卷 131-134页

作者： xian-Wei Dai Kai Ma Fu-xiang wang Fu-quan Yang bao-Sheng wang Hai-Ying Zhao Wei Sun bao-Lin liu Fang Qiu xian-Min Pu liang wang Yang Dai Department of General Surgery Second Clinical College China Medical University Shenyang 110004 China. daixianwei@***

OBJECTIVE: To introduce a new reconstructional procedure to deerease the complications ***: Separate internal drainage of bile and pancreatic fluid in pancreaticiduodenectomy wasperformed in 256 patients. The digestive tract was reconstructed with Child method, with invaginatedpancreaticojejunostomy using a long silastic tube to drain pancreatic fluid internally, an end-to-sidecholedochojejunostomy and an end-to-side duodenojejunostomy or gastrojejunostomy. Gastrostomy drainagewas also ***: No complications of pancreatic leakage were ***: The separate internal drainage of bile and pancreatic fluid plays an important role inpreventing pancreaticojejunal anastomotic leakage.

关键词： pancreaticoduodenectomy reconstruction internal drainage invaginated pancreaticojejunostomy pancreatic leakage gastrostomy drainage

Ascending aortic dilatation rate after transcatheter aortic valve replacement in patients with bicuspid and tricuspid aortic stenosis: A multidetector computed tomography follow-up study

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World Journal of Emergency Medicine 2019年第4期10卷 197-204页

作者： Yu-xin He Jia-qi Fan Qi-feng Zhu Qi-jing Zhou ju-bo Jiang Li-han wang Stella Ng xian-bao liu Jian-an wang Department of Cardiology the Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Department of Radiology the Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China

BACKGROUND: Current data is lacking about the progression of ascending aortic dilatation after transcatheter aortic valve replacement(TAVR) in aortic stenosis(AS) patients with bicuspid aortic valve(BAV) and tricuspid aortic valve(TAV). This study aims to assess the ascending aortic dilatation rate(mm/year) after TAVR in patients with BAV versus TAV using a multidetector computed tomography(MDCT) fol ow-up and to determine the predictors of ascending aortic dilatation ***: Severe AS patients undergoing TAVR from March 2013 to March 2018 at our center with MDCT follow-ups were included. BAV and TAV were identified using baseline MDCT. Baseline and follow-up MDCT images were analyzed,and the diameters of ascending aorta were measured. Study end point is ascending aortic dilatation rate(mm/year). Furthermore,factors predicting ascending aortic dilatation rate were also ***: Two hundred and eight patients were included,comprised of 86 BAV and 122 TAV patients. Five,4,3,2,and 1-year MDCT follow-ups were achieved in 7,9,30,46,and 116 patients. The ascending aortic diameter was significantly increased after TAVR in both BAV group(43.7±4.4 mm vs. 44.0±4.5 mm;P<0.001) and TAV group(39.1±4.8 mm vs. 39.7±5.1 mm;P<0.001). However,no difference of ascending aortic dilatation rate was found between BAV and TAV group(0.2±0.8 mm/year vs. 0.3±0.8 mm/year,P=0.592). Multivariate linear regression revealed paravalvular leakage(PVL) grade was independently associated with ascending aortic dilatation rate in the whole population and BAV group,but not TAV group. No aortic events occurred during ***: Ascending aortic size continues to grow after TAVR in BAV patients,but the dilatation rate is mild and comparable to that of TAV patients. PVL grade is associated with ascending aortic dilatation rate in BAV patients post-TAVR.

关键词： Transcatheter aortic valve replacement Aortic dilatation Bicuspid aortic valve

quantifying in situ N2 fluxes from an intensively managed calcareous soil using the 15N gas-flux method

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Journal of Integrative Agriculture 2022年第9期21卷 2750-2766页

作者： liu Yan wang Rui PAN Zhan-lei ZHENG Xun-hua WEI Huan-huan ZHANG Hong-rui MEI bao-ling quan Zhi FANG Yun-ting ju Xiao-tang State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry Institute of Atmospheric PhysicsChinese Academy of Sciences(CAS)Beijing 100029P.R.China College of Earth and Planet Science University of Chinese Academy of SciencesBeijing 100049P.R.China College of Resources and Environmental Sciences China Agricultural UniversityBeijing 100193P.R.China School of Ecology and Environment Inner Mongolia UniversityHohhot 010021P.R.China CAS Key Laboratory of Forest Ecology and Management Institute of Applied EcologyChinese Academy of SciencesShenyang 110164P.R.China College of Tropical Crops Hainan UniversityHaikou 570228P.R.China

Denitrification-induced nitrogen(N) losses from croplands may be greatly increased by intensive ***,the accurate quantification of these losses is still challenging due to insufficient available in situ measurements of soil dinitrogen(N) *** carried out two one-week experiments in a maize-wheat cropping system with calcareous soil using theN gas-flux(NGF) method to measure in situ Nfluxes following urea *** ofN-labeled urea(99 atom%,130-150 kg N ha) were followed by irrigation on the 1 st,3 rd,and 5 th days after fertilization(DAF 1,3,and 5,respectively).The detection limits of the soil Nfluxes were 163-1 565,81-485,and 54-281 μg N mhfor the two-,four-,and six-hour static chamber enclosures,*** Nfluxes measured in 120 cases varied between 159 and 2 943(811 on average) μg N *** were higher than the detection limits,with the exception of only two *** Nfluxes at DAF 3 were significantly higher(by nearly 80%(Paize experiment,while there were no significant differences among the irrigation times in the wheat *** Nfluxes and the ratios of nitrous oxide(NO) to the NO plus Nfluxes following urea application to maize were approximately 65% and 11 times larger,respectively(Painly attributed to the higher soil water contents,temperatures,and availability of soil N substrates in the maize experiment than in the wheat *** study suggests that theNGF method is sensitive enough to measure in situ Nfluxes from intensively fertilized croplands with calcareous soils.

关键词： N2 fluxes 15N gas-flux method N2O/(N2O+N2)ratios detection limit intensive cropping system