检索结果-南通市图书馆

Chinese Journal of Mechanical Engineering 2024年第3期37卷 275-288页

作者： Zheng Sun Zhongde Shan Hao Huang Dong wang wang wang Jiale Liu Chenchen Tan Chaozhong Chen Nanjing University of Aeronautics and Astronautics Nanjing 210016China School of Mechanical Engineering Beijing Institute of TechnologyBeijing 100081China CRRC Institute Corporation Limited Beijing 100070China

Thermal conductivity is one of the most significant criterion of three-dimensional carbon fiber-reinforced SiC matrix composites(3D C/SiC).Represent volume element(RVE)models of microscale,void/matrix and mesoscale proposed in this work are used to simulate the thermal conductivity behaviors of the 3D C/SiC *** entirely new process is introduced to weave the preform with three-dimensional orthogonal *** 3D steady-state analysis step is created for assessing the thermal conductivity behaviors of the composites by applying periodic temperature boundary *** RVE models of cuboid,hexagonal and fiber random distribution are respectively developed to comparatively study the influence of fiber package pattern on the thermal conductivities at the ***,the effect of void morphology on the thermal conductivity of the matrix is analyzed by the void/matrix *** prediction results at the mesoscale correspond closely to the experimental *** effect of the porosities and fiber volume fractions on the thermal conductivities is also taken into *** multi-scale models mentioned in this paper can be used to predict the thermal conductivity behaviors of other composites with complex structures.

关键词： 3D C/SiC composites Finite element analyses Multi-scale modeling Thermal conductivity

Efficient overall photosynthesis of H_(2)O_(2) by the BTz@Mn_(0.2)Cd_(0.8)S S-scheme heterojunction

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第6期67卷 1953-1960页

作者： Zhongyue Chen Sijie Wan Bei Cheng wang wang Yao Xiang Jiaguo Yu Shaowen Cao State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan430070China Hubei Technology Innovation Center for Advanced Composites Wuhan University of TechnologyWuhan430070China Hospital of Wuhan University of Technology Wuhan University of TechnologyWuhan430070China Laboratory of Solar Fuel Faculty of Materials Science and ChemistryChina University of GeosciencesWuhan430074China

The photosynthesis of hydrogen peroxide(H_(2)O_(2))through the selective 2e^(-)oxygen reduction reaction(ORR)from O_(2)and H_(2)O stands out as an environmentally sustainable and cost-effective method for generating this essential ***,the widespread application of most photocatalysts is impeded by their reliance on sacrificial *** this context,we present a noteworthy advancement in the form of a step-scheme(S-scheme)heterojunction involving a donor-acceptor(D-A)-conjugated polymer and manganese cadmium sulfide(BTz@MCS).This innovative configuration enables efficient photocatalytic H_(2)O_(2)production within a non-sacrificial system,showcasing an impressive H_(2)O_(2)yield of 5,368μmol g^(-1)h^(-1)and an apparent quantum yield of 4.5%at 420 *** insights gained from in-situ irradiated X-ray photoelectron spectroscopy(ISIXPS),in-situ diffuse reflectance infrared Fourier transformations spectroscopy(DRIFTS),and density function calculations(DFT),it is revealed that the sp^(2)C between thiazole-thiazole rings at the BTz and the concentrated holes at the MCS function as spatially separated redox *** centers catalyze the selective 2e^(-)ORR and 4e^(-)water oxidation reaction(WOR)*** O_(2)generated from the WOR is subsequently utilized by the ORR cycle,enabling the overall photosynthesis of H_(2)O_(2)with accelerated total reaction ***,the high photocatalytic performance of the developed catalyst is attributed to well-designed S-scheme heterojunctions with tuned band *** spatially separated redox centers and effective transfer of photogenerated charge carriers facilitated by the internal electric field significantly enhance reaction *** study introduces a promising avenue for photocatalytic H_(2)O_(2)production without sacrificial agents,providing valuable insights into the underlying mechanisms in S-scheme heterojunctions.

关键词： hydrogen peroxide non-sacrificial redox centers S-scheme heterojunction

Dry environment on the expression of lacrimal gland S100A9,Anxa1,and Clu in rats via proteomics

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2024年第3期17卷 435-443页

作者： Yi-Lin Sun A-Yuan Cui Li-Xin wang wang-wang Zhang Hong Shi College of Traditional Chinese Medicine Xinjiang Medical UniversityUrumqi 830011Xinjiang Uygur Autonomous RegionChina Research on High Incidence of Diseases in Xinjiang Region Key Laboratory of the Ministry of Education(Xinjiang Medical University)Urumqi 830011Xinjiang Uygur Autonomous RegionChina

●AIM:To investigate the underlying mechanism of dry environment(autumn dryness)affecting the lacrimal glands in rats.●METHODS:Twenty Sprague-Dawley rats were randomly divided into two *** rats were fed in specific pathogen free environment as the control group(n=10),and the rats fed in dry environment as the dryness group(n=10).After 24d,lacrimal glands were collected from the *** tissues morphology was observed by hematoxylineosin(HE)*** mass tags(TMT)quantitative proteomics analysis technology was used to screen the differential expressed proteins of lacrimal glands between the two groups,then bioinformatics analysis was ***,the immunohistochemical(IHC)method was used to verify the target proteins.●RESULTS:In dryness group,the lacrimal glands lobule atrophied,the glandular cavities enlarged,the sparse nuclear distribution and scattered inflammatory infiltration between the acinus were *** proteomics exhibited that a total of 195 up-regulated and 236 downregulated differential expressed proteins screened from the lacrimal glands of *** was indicated that the biological processes(BP)of differential expressed proteins mainly included cell processes and single *** cellular compositions of differential expressed proteins mainly located in cells,*** molecular functions of differential expressed proteins mainly included binding,catalytic ***,the Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis showed that the differential expressed proteins mainly involved lysosome,complement and coagulation cascade,and ribosome *** IHC result verified that the up-regulated expression proteins of Protein S100A9(S100A9),Annexin A1(Anxa1),and Clusterin(Clu)in lacrimal glands of rats in dryness group were higher than control group.●CONCLUSION:The up-regulated expression proteins of S100A9,Anxa1,and Clu may be the potential mechanisms of dry eye symptoms caused by dry *** study pr

关键词： dry eye lacrimal gland S100A9 Clu Anxa1 environment rats

Aspartoacylase suppresses prostate cancer progression by blocking LYN activation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Military Medical Research 2024年第2期11卷 180-205页

作者： Hong Weng Kang-Ping Xiong wang wang Kai-Yu Qian Shuai Yuan Gang wang Fang Yu Jun Luo Meng‑Xin Lu Zhong‑Hua Yang Tao Liu Xing Huang Hang Zheng Xing-Huan wang Department of Urology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Center for Evidence‑Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Biological Repositories Zhongnan Hospital of Wuhan UniversityWuhan 430071China Hubei Key Laboratory of Tumor Biological Behaviors Wuhan 430071China Department of Pathology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Center for Pathology and Molecular Diagnostics Wuhan UniversityWuhan 430071China Wuhan Research Center for Infectious Diseases and Cancer Chinese Academy of Medical SciencesWuhan 430071China

Background:Globally,despite prostate cancer(PCa)representing second most prevalent malignancy in male,the precise molecular mechanisms implicated in its pathogenesis remain ***,elucidating the key molecular regulators that govern disease progression could substantially contribute to the establishment of novel therapeutic strategies,ultimately advancing the management of ***:A total of 49 PCa tissues and 43 adjacent normal tissues were collected from January 2017 to December 2021 at Zhongnan Hospital of Wuhan *** advanced transcriptomic methodologies were employed to identify differentially expressed mRNAs in *** expression of aspartoacylase(ASPA)in PCa was thoroughly evaluated using quantitative real-time PCR and Western blotting *** elucidate the inhibitory role of ASPA in PCa cell proliferation and metastasis,a comprehensive set of in vitro and in vivo assays were conducted,including orthotopic and tumor-bearing mouse models(n=8 for each group).A combination of experimental approaches,such as Western blotting,luciferase assays,immunoprecipitation assays,mass spectrometry,glutathione S-transferase pulldown experiments,and rescue studies,were employed to investigate the underlying molecular mechanisms of ASPA's action in *** Student‘s t-test was employed to assess the statistical significance between two distinct groups,while one-way analysis of variance was utilized for comparisons involving more than two groups.A two-sided P<0.05 was deemed to indicate statistical ***:ASPA was identified as a novel inhibitor of PCa *** expression of ASPA was found to be significantly down-regulated in PCa tissue samples,and its decreased expression was independently associated with patients’prognosis(HR=0.60,95%CI 0.40–0.92,P=0.018).Our experiments demonstrated that modulation of ASPA activity,either through gain-or loss-of-function,led to the suppression or enhancement of PCa cell proliferation,mig

关键词： Prostate cancer Aspartoacylase LYN JNK AP-1 C-Jun Phosphorylation

Geographically and Temporally Weighted Regression in Assessing Dengue Fever Spread Factors in Yunnan Border Regions

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第5期37卷 511-520页

作者： ZHU Xiao Xiang wang Song wang LI Yan Fei ZHANG Ye Wu SU Xue Mei ZHAO Xiao Tao National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases Chinese Center for Disease Control and PreventionBeijing 102211China Yunnan Institute of Parasitic Diseases Pu’er 665000YunnanChina

Objective This study employs the Geographically and Temporally Weighted Regression(GTWR)model to assess the impact of meteorological elements and imported cases on dengue fever outbreaks,emphasizing the spatial-temporal variability of these factors in border *** We conducted a descriptive analysis of dengue fever’s temporal-spatial distribution in Yunnan border *** annual data from 2013 to 2019,with each county in the Yunnan border serving as a spatial unit,we constructed a GTWR model to investigate the determinants of dengue fever and their spatio-temporal heterogeneity in this *** The GTWR model,proving more effective than Ordinary Least Squares(OLS)analysis,identified significant spatial and temporal heterogeneity in factors influencing dengue fever’s spread along the Yunnan ***,the GTWR model revealed a substantial variation in the relationship between indigenous dengue fever incidence,meteorological variables,and imported cases across different *** In the Yunnan border areas,local dengue incidence is affected by temperature,humidity,precipitation,wind speed,and imported cases,with these factors’influence exhibiting notable spatial and temporal variation.

关键词： Dengue fever Meteorological factor Geographically and temporally weighted regression

Spectral observation of symmetry-protected selection rules for dynamical high-dimensional parity in alignment magnetic resonance

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2024年第10期Mechanics & Astronomy) .卷 5-15页

作者： Xu-Xing Geng Kai Jin Lu Zhou wang-wang Tang Guoqing Yang Shangqing Liang Shao-Ping Wu Guang-Ming Huang Gao-Xiang Li Department of Physics Huazhong Normal University State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal University College of Electronics and Information Hangzhou Dianzi University

Multidimensional Floquet-driven alignment systems with dynamical symmetry present various exotic phenomena and applications. However, there are challenges in directly characterizing large-spin dynamical symmetry from spectra. Here, we first observe the symmetry-protected selection rules of dynamical high-dimensional parity in a large-spin(F = 4) system. We theoretically construct a Floquet-driven alignment system that can be used to reveal high-dimensional spatiotemporal symmetry. In the experiment, the system is implemented in Cs atomic gas subjected to two-dimensional Floquet-modulated magnetic resonance driving. By developing Floquet detection protocols of alignment double-sided spectra, we directly verify symmetry-protected selection rules of dynamical high-dimensional parity for large-spin systems. This work advances the exploration of dynamical symmetry to large spins, and unravels a universal Floquet scheme for the investigation of symmetry-protected selection rules.

关键词： dynamical high-dimensional symmetry symmetry-protected selection rules large-spin alignment magnetic resonance Floquet two-mode detection

同方期刊数据库

Sulfonated poly(aryl ether ketone sulfone)modified by polyoxometalates LaW_(10) clusters for proton exchange membranes with high proton conduction performance

在线全文

学校读者我要写书评

暂无评论

Tungsten 2024年第2期6卷 454-464页

作者： Meng-Long Liu Xu Han Wen-Wen He Feng-Yu Jiang Fang Ji wang-wang Shen Tao Zhou Jing-Mei Xu Ya-Qian Lan School of Chemistry and Life Science Changchun University of TechnologyChangchun 130012China Advanced Institute of Materials Science Changchun University of TechnologyChangchun 130012China School of Chemistry South China Normal UniversityGuangzhou 510006China

Polyoxometalates(POMs)are classified as solid superacids which can exhibit notable proton conductivity,making them a promising functional inorganic filler for enhancing the proton conductivity of proton exchange membranes(PEMs).In this study,a series of hybrid membranes were obtained by molecular-level hybridization of Weakley-type POM Na_(7)H_(2)LaW_(10)O_(36)(LaW_(10))clusters into sulfonated poly(aryl ether ketone sulfone)(SPAEKS).All hybrid membranes exhibited greater proton conductivity than the pristine membrane in the 30–80℃temperature *** the doping amount of LaW 10 reached 7 wt.%,the proton conductivity of M-LaW 10^(-7)achieved 64 mS·cm^(−1)at 80℃.Lanthanide ions'high coordination number property and variable coordination environment can aid to attract more water molecules from the *** 10 and these bound water can construct denser hydrogen bonds with–SO_(3)H of *** intensive hydrogen bonds will facilitate the constitution of more continuous proton transport channels,and improve the proton conductivity of the hybrid *** work off ers a fresh approach to using POMs containing rare-earth components in PEMs.

关键词： Polyoxometalates Rare-earth elements Sulfonated poly(arylene ether ketone sulfone) Proton exchange membranes

Evaluation of the famous classic formula Sanhua decoction based on network pharmacology and multi-component quantitative analysis

在线全文

学校读者我要写书评

暂无评论

Traditional Medicine Research 2024年第1期9卷 1-13页

作者： Xin Zhang Wan-Cui wang Jin-Kui Zhang Wei-Mei Zhang Peng-wang wang Peng-Cheng Lin Yong-Chang Lu Xia Li Wen-Yuan Gao College of Pharmacy Qinghai Minzu UniversityXining 810000China Qinghai Key Laboratory of Phytochemistry on Qinghai-Tibet Plateau Qinghai Minzu UniversityXining 810000China School of Pharmaceutical Science and Technology Tianjin UniversityTianjin 300000China Qinghai Engineering Technology Research Center of Modern Tibetan Medicine Creation Qinghai Minzu UniversityXining 810000China

Background:Sanhua decoction has significant effects in the treatment of *** study of the Sanhua decoction material benchmark was carried out to analyze the value transfer relationship between the Chinese herbal pieces and the substance ***:Network pharmacology was employed to investigate the potential active components and molecular mechanisms of Sanhua decoction in the treatment of stroke.15 batches of Sanhua decoction lyophilized powder were prepared using traditional formulas and subjected to high-performance liquid chromatography analysis to generate fingerprints of the Sanhua decoction substance ***,a multi-component quantitative analysis method was established,allowing for the simultaneous determination of ten components,to study the transfer of quantity values between pieces and substance ***:60 active ingredients were screened from Sanhua decoction by network pharmacology,of which gallic acid,magnolol honokiol,physcion,and aloe-emodin may have a greater effect than other active components.63 key targets and 134 pathways were predicted as the potential mechanism of Sanhua decoction in treating *** fingerprint similarity of the Sanhua decoction substance benchmarks was found to be good among the 15 batches,confirming the 19 common *** content of the 10 components was basically *** components’transfer rates were within 30%of their respective ***:This study provided a comprehensive and reliable strategy for the quality evaluation of Sanhua decoction substance benchmarks and held significant importance in improving its application value.

关键词： Sanhua decoction classic famous formula HPLC fingerprinting value transfer network pharmacology

Efficient overall photosynthesis of HOby the BTz@MnCdS S-scheme heterojunction

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年

作者： Zhongyue Chen Sijie Wan Bei Cheng wang wang Yao Xiang Jiaguo Yu Shaowen Cao Hubei Technology Innovation Center for Advanced Composites Wuhan University of Technology State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology Hospital of Wuhan University of Technology Wuhan University of Technology Laboratory of Solar Fuel Faculty of Materials Science and Chemistry China University of Geosciences

The photosynthesis of hydrogen peroxide(H2O2) through the selective 2 e-oxygen reduction reaction(ORR) from O2and H2O stands out as an environmentally sustainable and cost-effective method for generating this essential ***,the widespread application of most photocatalysts is impeded by their reliance on sacrificial *** this context,we present a noteworthy advancement in the form of a step-scheme(S-scheme) heterojunction involving a donor-acceptor(D-A)-conjugated polymer and manganese cadmium sulfide(BTz@MCS).This innovative configuration enables efficient photocatalytic H2O2production within a non-sacrificial system,showcasing an impressive H2O2yield of 5,368 μmol g-1h-1and an apparent quantum yield of 4.5% at 420 *** insights gained from in-situ irradiated X-ray photoelectron spectroscopy(ISIXPS),in-situ diffuse reflectance infrared Fourier transformations spectroscopy(DRIFTS),and density function calculations(DFT),it is revealed that the sp2C between thiazole-thiazole rings at the BTz and the concentrated holes at the MCS function as spatially separated redox *** centers catalyze the selective 2 e-ORR and 4 e-water oxidation reaction(WOR) *** O2generated from the WOR is subsequently utilized by the ORR cycle,enabling the overall photosynthesis of H2O2with accelerated total reaction ***,the high photocatalytic performance of the developed catalyst is attributed to well-designed S-scheme heterojunctions with tuned band *** spatially separated redox centers and effective transfer of photogenerated charge carriers facilitated by the internal electric field significantly enhance reaction *** study introduces a promising avenue for photocatalytic H2O2production without sacrificial agents,providing valuable insights into the underlying mechanisms in S-scheme heterojunctions.

关键词：

基于改进YOLO v8s的羊只行为识别方法

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

农业机械学报 2024年第7期55卷 325-335,344页

作者：王旺王福顺张伟进刘红达王晨王超何振学河北农业大学信息科学与技术学院保定071001 河北省农业大数据重点实验室保定071001

羊只站立、行走、采食等日常行为与其健康状况密切相关,高效、准确的羊只行为识别有助于疾病检测,对实现羊只健康预警具有重要意义。针对目前羊只多行为识别检测大多基于传感器等接触式设备,羊只活动受限,行为具有局限性,且群体养殖环境... 详细信息

羊只站立、行走、采食等日常行为与其健康状况密切相关,高效、准确的羊只行为识别有助于疾病检测,对实现羊只健康预警具有重要意义。针对目前羊只多行为识别检测大多基于传感器等接触式设备,羊只活动受限,行为具有局限性,且群体养殖环境下,羊只行为多样、场景复杂、存在遮挡等造成的行为识别精度低等问题,提出了一种基于改进YOLO v8s的羊只行为识别方法。首先,引入SPPCSPC空间金字塔结构增强了模型的特征提取能力,提升了模型的检测精度。其次,新增P2小目标检测层,增强了模型对小目标的识别和定位能力。最后,引入多尺度轻量化模块PConv和EMSConv,在保证模型识别效果的同时,降低了模型参数量和计算量,实现了模型轻量化。实验结果表明,改进YOLO v8s模型对羊只站立、行走、采食、饮水、趴卧行为平均识别精度分别为84.62%、92.58%、87.54%、98.13%和87.18%,整体平均识别精度为90.01%。与Faster R-CNN、YOLO v5s、YOLO v7、YOLO v8s模型相比,平均识别精度分别提高12.03、3.95、1.46、2.19个百分点。研究成果可为羊只健康管理和疾病预警提供技术支撑。

关键词：羊行为识别 YOLO v8s 轻量化

同方期刊数据库博看期刊