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Regional differences in global glacier retreat from 1980 to 2015

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Advances in Climate Change Research 2019年第4期10卷 203-213页

作者： LI Yao-jun DING Yong-Jian SHANGGUAN Dong-Hui wang rong-jun State Key Laboratory of Cryospheric Science Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou730000China Key Laboratory of Ecohydrology of Inland River Basin Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou730000China University of Chinese Academy of Sciences Beijing100049China

Global warming triggers shrinking and thinning of glaciers worldwide,with potentially severe implications for human ***,regional differences in glacier retreat and its relationship with climatic characteristics have not been conclusively *** this study,regional changes in global glaciers based on two primary features,area change and mass balance,were investigated on the basis of data collected from published research on glacier *** show that during the period 1980—2015,the rate of global glacier area shrinkage was 0.18%per year and that of global glacier mass loss was 0.25 m *** *** of glaciers located at low and middle latitudes was characterized by severe area shrinkage and mass ***,in the Arctic,deglaciation was characterized by ice thinning due to a low area reduction but relatively high mass loss ***,glaciers in high southern latitudes were in a relatively stable *** Mountain Asia exhibited the lowest rate of area shrinkage and mass loss among glaciers located at low and middle latitudes,and a slower rate of mass loss compared with the global *** in the Tropical Andes exhibited the fastest rate of glacier area shrinkage(—1.6%per year),whereas Antarctic and Subantarctic glaciers showed the lowest rate(—0.11%per year).For mass balance,the most negative occurred at Southern Andes(—0.81 m *** year),followed by Alaska(-0.74 m *** year).Only the Antarctic and Subantarctic experienced small mass gain(0.04 m *** year).High levels of correlation are found between the rates of glacier retreat and annual average temperature and annual total precipitation instead of their *** variability of the surface climate conditions in the glacier environment plays a key role in driving these regional differences in global glacier retreat.

关键词： Glacier retreat Regional differences Climate change

Effects of ethanol on the in situ synthesized Cu/SiO_2 catalyst:Texture,structure,and the catalytic performance in hydrogenation dimethyl oxalate to ethylene glycol

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Chinese Chemical Letters 2011年第3期22卷 362-365页

作者： Shu rong wang Ling jun Zhu Ying Ying Zhu Xiao Lan Ge Xin Bao Li State Key Laboratory of Clean Energy Utilization Zhejiang University Hangzhou 310027 China

The Cu/SiO_2 catalysts were in situ synthesized by the hydrolysis of tetraethyl orthosilicate（TEOS） in one phase solution using ethanol as co-solvent or TEOS/H_2O two phases solution,followed by the precipitation of copper on SiO_2 by ammonia evaporation. In the hydrogenation of dimethyl oxalate,the catalyst prepared by one phase hydrolysis exhibited higher activity and ethylene glycol（EG） selectivity at lower temperature than that of two phases due to its larger BET surface area and multimodal pore *** 488-503 K,the catalyst prepared in one phase solution with water/ethanol（W/E） volume ratio of 3：1 exhibited 90- 95%EG selectivity,while catalyst prepared by two phase hydrolysis reached 90%EG selectivity only at 498-503 K.

关键词： Ethanol Cu/SiO2 TEOS Hydrogenation Dimethyl oxalate Ethylene glycol

十二指肠贾第虫包囊壁蛋白CWP2和CWP3的表达纯化与生物信息学分析

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中国预防兽医学报 2024年第3期46卷 254-261页

作者：张雅芳吴善博邵天人边啸坤孙露露王荣军河南农业大学动物医学院河南郑州450046

为体外表达与纯化十二指肠贾第虫包囊壁蛋白CWP2和CWP3并分析其生物信息学特征,本研究采用PCR从十二指肠贾第虫全基因组中扩增CWP2与CWP3基因,并构建重组表达载体p ET-28a-CWP2和p ET-28a-CWP3,经酶切与测序鉴定正确后转化大肠杆菌BL21(... 详细信息

为体外表达与纯化十二指肠贾第虫包囊壁蛋白CWP2和CWP3并分析其生物信息学特征,本研究采用PCR从十二指肠贾第虫全基因组中扩增CWP2与CWP3基因,并构建重组表达载体p ET-28a-CWP2和p ET-28a-CWP3,经酶切与测序鉴定正确后转化大肠杆菌BL21(DE3)感受态细胞,经IPTG诱导后超声破碎,采用尿素纯化蛋白并经SDS-PAGE和western blot检测重组蛋白的表达与纯化效果。SDS-PAGE结果显示,表达的重组CWP2和CWP3蛋白(rCWP2及r CWP3)分别为38.79 ku和27.38 ku,且两种重组蛋白主要以包涵体形式表达,纯化后的蛋白条带单一且纯度均大于90%;western blot结果显示纯化的两种重组蛋白与His-tag单克隆抗体(MAb)的反应原性均较好。采用BCA法测定r CWP2及r CWP3的浓度分别为0.207 mg/mL及0.465 mg/mL。通过Prot Param、Prot Scale、Singal P 6.0、Deep TMHMM、NetPhos 3.1、SOPMA、SWISS MODEL和STRING等生物信息学软件预测这两个重组蛋白的生物信息学特性。结果显示,十二指肠贾第虫CWP2和CWP3分别为不稳定性和稳定性蛋白,有信号肽,无跨膜区,各有39个和25个磷酸化位点,均形成了氧化(O)-磷酸化。CWP2和CWP3的主要二级结构为α-螺旋和无规则卷曲;预测的三级结构模型中CWP2和CWP3与十二指肠贾第虫WB克隆C6株及P15株中的E2RTS7.1.A和E1F7Q8.1.A氨基酸序列的同源性分别达100%及90.69%。三级结构模型显示这两个蛋白也均以α-螺旋和无规则卷曲为主,与二级结构相符;CWP2与α-1贾第素、DNA解旋酶等7个蛋白存在相互作用关系;CWP3与α-2贾第素、δ-贾第素和β-贾第素存在相互作用关系。上述结果表明,本研究获得了高纯度高水平表达的r CWP2及r CWP3,且反应原性均较强,并分析了二者的主要生物信息学特征,为十二指肠贾第虫包囊壁蛋白的深入探究奠定了基础。

关键词：十二指肠贾第虫囊壁蛋白原核表达纯化生物信息学分析

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职业学校支持中小学职业启蒙教育的现状调查

职业教育研究 2024年第1期 11-15页

作者：陆春庚刘娟王荣军颜媛媛扬州市江都区教育局江苏扬州225200 江苏省江都中等专业学校江苏扬州225212

职业学校“支持”中小学开展职业启蒙教育,已经成为国家层面的教育战略。调查发现,在“支持”作用上,更接受职教优势的发挥;在“支持”内容上,更看重职业兴趣的培养;在“支持”方式上,更聚焦实训基地的体验;在“支持”评价上,更认可劳... 详细信息

职业学校“支持”中小学开展职业启蒙教育,已经成为国家层面的教育战略。调查发现,在“支持”作用上,更接受职教优势的发挥;在“支持”内容上,更看重职业兴趣的培养;在“支持”方式上,更聚焦实训基地的体验;在“支持”评价上,更认可劳动意识的增强。因此,可以从提高认识,聚焦“支持”的使命感;优化内容,关注“支持”的满意度;改善方式,增强“支持”的吸引力;创新评价,找准“支持”的关键点等四个方面优化“支持”的质态,助力职普融通的推进。

关键词：职业学校中小学职业启蒙教育劳动教育职普融通

Reinforcement of High Impact Polystyrene by Aramid Nanoparticle Fillers Prepared via an In situ Bottom-up Approach

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Chinese Journal of Polymer Science 2024年第8期42卷 1167-1176页

作者： Xiang-jun Gong Zhi-Ping Zhao Chang-Mei Sun Ying Zhang rong-jun Qu Ying wang School of Chemistry and Materials Science Ludong UniversityYantai 264025China

In this work,aramid nanoparticles(ANPs)were prepared in dimethyl formamide(DMF)solution containing high impact polystyrene(HIPS)via a bottom-up *** electron microscopy(TEM)images showed that the obtained ANPs were evenly distributed in the HIPS matrix without any *** composition of the ANPs,i.e.,poly(p-phenyl-p-phenylenediamine)(PPTA),was confirmed by Fourier transform infrared spectroscopy(FTIR),X-ray photoelectron spectroscopy(XPS)and X-ray diffractometer(XRD).The ANP/HIPS composites,obtained after ethanol precipitation,were added to neat HIPS as fillers to fabricate ANP/HIPS composite *** surface roughness and the glass transition temperature(T_g)of the sheets were characterized by atomic force microscope(AFM)and differential scanning calorimetry(DSC),*** with neat HIPS,the mechanical properties of the composite sheet were significantly improved,and the Young's modulus increased from 246.55 MPa to 2025.12 MPa,the tensile strength increased from 3.07 MPa to 29.76 MPa,and the toughness increased from 0.32 N/mm^2 to 3.92 N/mm^2,with an increase rate of 721%,869%and 1125%,***,the thermal stability of the composites improved with the increase in ANP content.

关键词： High impact polystyrene PPTA nanoparticle Reinforce Mechanical property

MicroRNA-mediated Silencing of RhoC Inhibits Tumor Invasion and Increases Chemosensitivity to Paclitaxel in SKOV3 Cells in vitro

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Chemical Research in Chinese Universities 2011年第1期27卷 70-74页

作者： PAN Ying DU Zhen-wu LENG Wei-chun ZHOU Jia-wen wang Ying-jian SHENG Min-jia wang jun-rong ZHANG Gui-zhen China-Japan Union Hospital of Jilin University Changchun 130031 P. R. China

RhoC is a member of the Ras-homologous family of genes which are implicated in tumorigenesis and tumor progression. Up-regulation of RhoC is associated with tumor progression in ovarian carcinoma and RhoC is significantly correlated with the invasive capability of ovarian cancer cell lines in vitro, We developed a system that blocks RhoC in the human ovarian cancer SKOV3 cells using specific MicroRNA（miRNA） interference. By transfecting SKOV3 cells with the plasmid vector to express specific MiRNA that targets human RhoC, we were able to establish a stable clone in which RhoC expression was significantly downregulated. This resulted in the decreased invasive potential of SKOV3 cells as well as increased chemosensitivity to paclitaxel. RhoC involves in invasion and chemosensitivity of SKOV3, indicating that RhoC may be a promising therapeutic target for ovarian cancer.

关键词： RhoC gene miRNA SKOV3 cell Cell invasion Paclitaxel

Self-Triggered Set Stabilization of Boolean Control Networks and Its Applications

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IEEE/CAA Journal of Automatica Sinica 2024年第7期11卷 1631-1642页

作者： rong Zhao jun-e Feng Dawei Zhang the School of Mathematics Shandong UniversityShandong UniversityJinan 250100China

Set stabilization is one of the essential problems in engineering systems, and self-triggered control(STC) can save the storage space for interactive information, and can be successfully applied in networked control systems with limited communication resources. In this study, the set stabilization problem and STC design of Boolean control networks are investigated via the semi-tensor product technique. On the one hand, the largest control invariant subset is calculated in terms of the strongly connected components of the state transition graph, by which a graph-theoretical condition for set stabilization is derived. On the other hand, a characteristic function is exploited to determine the triggering mechanism and feasible controls. Based on this, the minimum-time and minimum-triggering open-loop, state-feedback and output-feedback STCs for set stabilization are designed,respectively. As classic applications of self-triggered set stabilization, self-triggered synchronization, self-triggered output tracking and self-triggered output regulation are discussed as well. Additionally, several practical examples are given to illustrate the effectiveness of theoretical results.

关键词： Boolean control networks(BCNs) output regulation self-triggered control semi-tensor product of matrices set stabilization synchronization

A multifunctional shear apparatus for rocks subjected to true triaxial stress and high temperature in real-time

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第9期16卷 3524-3543页

作者： jun Zhao Xia-Ting Feng Jia-rong wang Liang Hu Yue Guo Key Laboratory of Ministry of Education on Safe Mining of Deep Metal Mines Northeastern UniversityShenyang110819China Key Laboratory of Liaoning Province on Deep Engineering and Intelligent Technology Northeastern UniversityShenyang110819China

Deep engineering disasters,such as rockbursts and collapses,are more related to the shear slip of rock joints.A novel multifunctional device was developed to study the shear failure mechanism in *** this device,the complete shearedeformation process and long-term shear creep tests could be performed on rocks under constant normal stiffness(CNS)or constant normal loading(CNL)conditions in real-time at high temperature and true-triaxial *** the research and development process,five key technologies were successfully broken through:(1)the ability to perform true-triaxial compressioneshear loading tests on rock samples with high stiffness;(2)a shear box with ultra-low friction throughout the entire stress space of the rock sample during loading;(3)a control system capable of maintaining high stress for a long time and responding rapidly to the brittle fracture of a rock sample as well;(4)a refined ability to measure the volumetric deformation of rock samples subjected to true triaxial shearing;and(5)a heating system capable of maintaining uniform heating of the rock sample over a long *** developing these technologies,loading under high true triaxial stress conditions was *** apparatus has a maximum normal stiffness of 1000 GPa/m and a maximum operating temperature of 300*** differences in the surface temperature of the sample are constant to within5*** types of true triaxial shear tests were conducted on homogeneous sandstone to verify that the apparatus has good performance and *** results show that temperature,lateral stress,normal stress and time influence the shear deformation,failure mode and strength of the *** novel apparatus can be reliably used to conduct true-triaxial shear tests on rocks subjected to high temperatures and stress.

关键词： True-triaxial shear apparatus Rocks Complete shear stressedeformation process Creep Real-time high-temperature

Structural Properties of Ions and Polyelectrolytes in Aqueous Solutions under External Electric Fields:The Sign Effect

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Chinese Journal of Polymer Science 2024年第9期42卷 1341-1352,I0007页

作者： Cheng-Jiang Lin jun-jun wang Yuan Jiang Shu-Li Chen Hong-Fei Li Wen-Han Zhao Qing-rong Huang Chang-Ru rong Xiao-Zheng Duan State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei230026China National Key Laboratory of Advanced Vehicle Integration and Control China FAW Group Co.Ltd.Changchun130013China State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai200438China Department of Food Science Rutgers University65 Dudley RoadNew BrunswickNew Jersey08901USA

We utilize molecular dynamics simulations to investigate the microstructures of ions and polyelectrolytes in aqueous solutions under external electric *** focusing on the multi-body interactions between ionic components and H_(2)O molecules,as well as their responses to the external electric fields,we clarify several nontrivial molecular features of the ionic and polyelectrolyte solutions,such as the solvations of cations and anions,clustering of the ions,and dispersions/aggregations of polyelectrolyte chains,as well as the corresponding responses of H_(2)O molecules in these *** simulations illustrate the variations in structures of ionic solutions caused by reversing the charge sign of the ions,and elucidate the disparity in structures between anionic and cationic polyelectrolyte solutions in the presence of the external electric *** work clarifies the mechanism for the alternations in complex multi-body interactions in aqueous solutions caused by the application electric field,which can contribute to the fundamental understanding of the physical and chemical natures of ion-containing and charged polymeric systems.

关键词： Polyelectrolyte Ions Aqueous solutions External electric fields Asymmetric dipole