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A systematic study of Erzhu Erchen decoction against damp-heat internalized type 2 diabetes based on data mining and experimental verification

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Traditional Medicine Research 2024年第2期9卷 27-41页

作者： Peng-Yu wang Jian-Fen Shen Shuo Zhang qing Lan Guan-Di Ma tong wang You-Zhi Zhang School of Pharmacy Hubei Engineering Research Center of Traditional Chinese Medicine of South Hubei ProvinceXianning Medical CollegeHubei University of Science and TechnologyXianning 437100China Department of Central Laboratory The First Affiliated Hospital of Jiaxing UniversityJiaxing 314000China

Background:Erzhu Erchen decoction(EZECD),which is based on Erchen decoction and enhanced with Atractylodes lancea and Atractylodes macrocephala,is widely used for the treatment of dampness and heat(The clinical manifestations of Western medicine include thirst,inability to drink more,diarrhea,yellow urine,red tongue,et al.)internalized ***,the mechanism of EZECD on damp-heat internalized Type 2 diabetes(T2D)remains *** employed data mining,pharmacology databases and experimental verification to study how EZECD treats damp-heat internalized ***:The main compounds or genes of EZECD and damp-heat internalized T2D were obtained from the pharmacology ***,the overlapped targets of EZECD and damp-heat internalized T2D were performed by the Gene Ontology,kyoto encyclopedia of genes and genomes *** the compound-disease targets-pathway network were constructed to obtain the hub ***,the hub genes and core related pathways were mined with weighted gene co-expression network analysis based on Gene Expression Omnibus database,the capability of hub compound and genes was valid in AutoDock ***,and violin plot and gene set enrichment analysis were performed to explore the role of hub genes in damp-heat internalized ***,the interactions of hub compound and genes were explored using Comparative Toxicogenomics Database and quantitative polymerase chain ***:First,herb-compounds-genes-disease network illustrated that the hub compound of EZECD for damp-heat internalized T2D could be ***,the hub genes were CASP8,CCL2,and AHR according to weighted gene co-expression network *** docking showed that quercetin could bind with the hub ***,gene set enrichment analysis and Gene Ontology represented that CASP8,or CCL2,is negatively involved in insulin secretion response to the TNF or lipopolysaccharide process,and AHR or CCL2 positively regulated li

关键词： data mining damp-heat internalized type 2 diabetes Erzhu Erchen decoction network pharmacology bioinformatics

Cascade electrolysis and thermocatalysis: a reliable system for upgrading C1 to C4 hydrocarbons

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Rare Metals 2024年第1期43卷 410-412页

作者： Chao-Yue Sun Wen Li Hai-qing wang Institute for Advanced Interdisciplinary Research(iAIR) College of Chemistry and Chemical EngineeringUniversity of JinanJinan 250022China

The carbon cycle is important for maintaining a stable climate and carbon balance on Earth. Renewable-electricitydriven upcycling of carbon dioxide (CO_(2)) into value-added multi-carbon molecules is a potentially sus... 详细信息

关键词： cycling hydrocarbons enable

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用HQ管抑制管道风扇噪声的数值模拟

工程热物理学报 2008年第9期29卷 1491-1494页

作者：洪志亮王同庆北京航空航天大学流体与声学工程实验室北京100083

针对HQ管抑制风扇噪声这一主动控制噪声的方法开展研究,包括理论分析和数值模拟,在圆管情况下使用HQ管的消声效果预测和HQ管各几何参数对消声效果影响的讨论。结果表明:HQ管在抑制风扇低频噪声方面有十分显著的效果。

关键词：风扇噪声气动声学 HQ管

A strategy for strengthening chaotic mixing of dual shaft eccentric mixers by changing non-Newtonian fluids kinetic energy distribution

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Chinese Journal of Chemical Engineering 2024年第5期69卷 122-134页

作者： Songsong wang tong Meng Qian Zhang Changyuan Tao Yundong wang Zequan Li Zuohua Liu School of Chemistry and Chemical Engineering Chongqing UniversityChongqing 400044China State Key Laboratory of Coal Mine Disaster Dynamics and Control Chongqing 400044China Department of Chemical Engineering Tsinghua UniversityBeijing 100084China

Efficiently modulating the velocity distribution and flow pattern of non-Newtonian fluids is a critical challenge in the context of dual shaft eccentric mixers for process intensification,posing a significant barrier for the existing ***,this work reports a convenient strategy that changes the kinetic energy to controllably regulate the flow patterns from radial flow to axial *** showed that the desired velocity distribution and flow patterns could be effectively obtained by varying the number and structure of baffles to change kinetic energy,and a more uniform velocity distribution,which could not be reached normally in standard baffle dual shaft mixers,was easily ***,a comparative analysis of velocity and shear rate distributions is employed to elucidate the mechanism behind the generation of flow patterns in various dual-shaft eccentric ***,there is little difference in the power number of the laminar flow at the same Reynolds number,meaning that the baffle type has no effect on the power consumption,while the power number of both unbaffle and U-shaped baffle mixing systems decreases compared with the standard baffle mixing system in the transition ***,at the same rotational condition,the dimensionless mixing time of the U-shaped baffle mixing system is 15.3%and 7.9%shorter than that of the standard baffle and the unbaffle mixing system,respectively,which shows the advantage of the U-shaped baffle in stirring rate.

关键词： Dual shaft “U-shaped”baffle Flow pattern Mixing time Power demand

Phase induced localization transition

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Chinese Physics B 2024年第10期33卷 362-365页

作者： tong Liu Xingbo Wei Youguo wang School of Science Nanjing University of Posts and TelecommunicationsNanjing 210003China Department of Physics and Key Laboratory of Optical Field Manipulation of Zhejiang Province Zhejiang Sci-Tech UniversityHangzhou 310018China

Localization phenomenon is an important research field in condensed matter ***,due to the complexity and subtlety of disordered systems,new localization phenomena always emerge *** example,it is generally believed that the phase of the hopping term does not affect the localization properties of the system,so the calculation of the phase is often ignored in the study of ***,we introduce a quasiperiodic model and demonstrate that the phase change of the hopping term can significantly alter the localization properties of the system through detailed numerical simulations,such as the inverse participation ratio and multifractal *** phase-induced localization transition provides valuable information for the study of localization physics.

关键词： phase localization quasiperiodic

Rheological Behaviors of Polymers with Nanoparticles Tethered at Each End

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Chinese Journal of Polymer Science 2024年第3期42卷 400-406,I0009页

作者： Song-Qi Zhang Wen-qing wang Jia-Ping Lin Li-Quan wang Shanghai Key Laboratory of Advanced Polymeric Materials Key Laboratory for Ultrafine Materials of Ministry of EducationSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China

The polymer with nanoparticles tethered at each end is a unique model for unraveling the effect of chain ends on the polymer dynamics. We investigated the rheological behavior of this kind of polymer by using nonequilibrium molecular dynamics simulation. The effect of polymer lengths and nanoparticle radii on the complex moduli and viscosity was examined. The dependence of complex moduli on the frequency becomes less pronounced as the polymer is short or the nanoparticle is large. The shear thinning behavior was revealed for these systems, and the scaling exponent of complex viscosity with respect to the frequency was found to change from-1/2 to-3/4 as the polymer shortens or the nanoparticle enlarges. The rheological behavior was further explained by analyzing the mean square distance of nanoparticles. The simulation results were compared with the existing experimental finding, showing an agreement. The work provides information for understanding the chain end effect on polymer rheology.

关键词： Polymer rheology Modulus Viscosity Molecular dynamics

Prescribed Performance Tracking Control of Time-Delay Nonlinear Systems With Output Constraints

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IEEE/CAA Journal of Automatica Sinica 2024年第7期11卷 1557-1565页

作者： Jin-Xi Zhang Kai-Di Xu qing-Guo wang IEEE the State Key Laboratory of Synthetical Automation for Process Industries Northeastern UniversityShenyang 110819China Institute of Artificial Intelligence and Future Networks Beijing Normal UniversityZhuhai 519087 Guangdong Key Laboratory of Artificial Intelligence and Multi-Modal Data Processing Beijing Normal University-Hong Kong Baptist University United International CollegeZhuhai 519087

The problem of prescribed performance tracking control for unknown time-delay nonlinear systems subject to output constraints is dealt with in this paper. In contrast with related works, only the most fundamental requirements, i.e., boundedness and the local Lipschitz condition, are assumed for the allowable time delays. Moreover, we focus on the case where the reference is unknown beforehand, which renders the standard prescribed performance control designs under output constraints infeasible. To conquer these challenges, a novel robust prescribed performance control approach is put forward in this ***, a reverse tuning function is skillfully constructed and automatically generates a performance envelop for the tracking error. In addition, a unified performance analysis framework based on proof by contradiction and the barrier function is established to reveal the inherent robustness of the control system against the time delays. It turns out that the system output tracks the reference with a preassigned settling time and good accuracy,without constraint violations. A comparative simulation on a two-stage chemical reactor is carried out to illustrate the above theoretical findings.

关键词： Nonlinear systems output constraints prescribed performance reference tracking time delays

Lightweight Si_(3)N_(4)@SiO_(2) ceramic foam for thermal insulation and electromagnetic wave transparency

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Nano Research 2024年第5期17卷 4298-4306页

作者： Zongwei tong Xiangjie Yan Yuexiang wang Kexun Li Weihai Ma China-Blarus Belt and Road Joint Laboratory on Electromagnetic Environment Effect the 33rd Research Institute of ChinaElectronics Technology Group CorporationTaiyuan 030032China Key Laboratory for Advanced Ceramics and Machining Technology of Ministry of Education School of Material Science and EngineeringTianjin UniversityTianjin 300072China Department of Materials Science and Engineering Jinzhong UniversityJinzhong 030619China

Increasing porosity is one of the most direct ways to improve the thermal insulation and dielectric properties of *** now,many wet methods for preparing Si_(3)N_(4) ceramic foams usually face the problems of complex rheology,long period,and expensive cost,and the reported pore sizes of Si_(3)N_(4) ceramic foams are typically micron-grade,resulting in a lack of competitiveness in thermal insulation and wave-transparent *** this paper,the Si_(3)N_(4)@SiO_(2) ceramic foams were prepared using an efficient dry-method,which combined three processes of low temperature chemical vapor deposition(LTCVD),template,and isostatic *** method has the advantages of simple operation and short preparation period,and can realize near-net size molding and mass *** addition,the evolution mechanisms of honeycomb microstructure and composition of Si_(3)N_(4)@SiO_(2) ceramic foam during sintering were studied by chemical reaction *** as-prepared Si_(3)N_(4)@SiO_(2) ceramic foam possesses low density(0.377 g·cm^(-3)),high compressive strength(7.5 MPa),low thermal conductivity(0.0808 W·m^(-1)·K^(-1)),and excellent dielectric properties(ε<1.32,tanδ<0.009)in the frequency range of 8-18 GHz,and its maximum working temperature in air can reach up to 1100℃.It will be recommended to be applied in the interlayer of Si_(3)N_(4) ceramic radome to improve its thermal insulation and electromagnetic wave transparency performances.

关键词： silicon nitride ceramic foam honeycomb microstructure dielectric properties thermal insulation

Continuous-wave operation of 1550 nm low-threshold triple-lattice photonic-crystal surface-emitting lasers

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Light(Science & Applications) 2024年第3期13卷 446-453页

作者： Ziye wang Xia Liu Pinyao wang Huanyu Lu Bo Meng Wei Zhang Lijie wang Yanjing wang Cunzhu tong State Key Laboratory of Luminescence and Applications Changchun Institute of OpticsFine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China Central Research Institute Planning Dept 2012 LabsHuawei Technologies Company Ltd.Shenzhen 518129China

Benefitting from narrow beam divergence,photonic crystal surface-emitting lasers are expected to play an essential role in the ever-growing fields of optical communication and light detection and *** operating with 1.55μm wavelengths have attracted particular attention due to their minimum fiber loss and high eye-safe ***,high interband absorption significantly decreases their performance at this 1.55μm ***,stronger optical feedback is needed to reduce their threshold and thus improve the output *** this goal,photonic-crystal resonators with deep holes and high dielectric contrast are often ***,the relevant techniques for high-contrast photonic crystals inevitably complicate fabrication and reduce the final *** this paper,we demonstrate the first continuous-wave operation of 1.55μm photonic-crystal surface-emitting lasers by using a‘triple-lattice photonic-crystal resonator’,which superimposes three lattice point groups to increase the strength of in-plane optical *** this geometry,the in-plane 180°coupling can be enhanced threefold compared to the normal single-lattice *** theoretical and experimental investigations demonstrate the much lower threshold current density of this structure compared to‘single-lattice’and‘double-lattice’photonic-crystal resonators,verifying our design *** findings provide a new strategy for photonic crystal laser miniaturization,which is crucial for realizing their use in future high-speed applications.

关键词： resonator crystal lattice