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Catalase promotes whitefly adaptation to high temperature by eliminating reactive oxygen species

Insect Science 2023年第5期30卷 1293-1308页

作者： peng liang Jie {2. Wenlu {2. Pu Zhu lianyou Gui Wen Xie Youjun Zhang Forewarning and Management of Agricultural and Forestry Pests Hubei Engineering Technology CenterInstitute of InsectCollege of AgricultureYangtze UniversityJingzhouHubei ProvinceChina Department of Plant Protection Institute of Vegetables and FlowersChinese Academy of Agricultural SciencesBeijingChina Jinhua Academy of Agricultural sciences JinhuaZhejiangChina

Thermal stress usually leads to excessive production of reactive oxygen species(ROS)in all aerobic ***(CAT)are the key antioxidant enzymes,which act as the first line of defense against ROS in the antioxidant *** highly invasive and widely distributed whitefly Bemisia tabaci MED damages plants by feeding as well as by transmitting many plant *** studies have shown that strong adaptability to high temperature helps explain the spread of MED around the ***,the mechanism underlying high temperature adaptation of this pest is not well *** this study,6 CAT genes were identified from the MED genome and transcriptome dataset,among which BtCAT1,BtCAT2.and BtCAT3 were found to be highly expressed in *** expression of BtCAT1,BtCAT2.or BtCAT3 increased with induction temperature and induction *** MED was exposed with mean high temperature(30℃ or 35℃)and a short-term extremely high temperature(39℃ or 41℃)after the silencing of BtCAT1,BtCAT2.or BtCAT3 to significantly increased ROS levels by at least 0.5 times and significantly decreased survival rate and fecundity of MED *** ROS level in the treated specimens gradually returned to a normal level after 2. h at 2.℃,but the survival rate still declined *** together,our results demonstrate that CAT could help *** adapt to long-term mean high temperatures and short-term extremely high temperatures by eliminating excessive ROS.

关键词： catalase fecundity reactive oxygen species survival rate temperature adap-tation mechanism whitefly

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Traditional Chinese Medicine syndrome elements of male infertility revealed by latent tree model analysis

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Journal of Traditional Chinese Medicine 2018年第6期38卷 926-935页

作者： Zhang Zhijie liu Shaoming Zhang Yueyang Yang Jingzhe Kong Tao wang Chengli ning {2. Chen Xiaochao li Xuesong Jia Yusen Chen Xiaojun Department of Urology and Andrology Dongfang Hospital of Beijing University of Traditional Chinese Medicine Department of Urology The Third Affiliated Hospital of Beijing University of Traditional Chinese Medicine Department of Andrology Wangjing Hospital of China Academy of Chinese Medical Science

OBJECTIVE: To explore the features of Traditional Chinese Medicine(TCM) syndromes in male infertility using computer-based ***: Latent class analysis was used to analyze the TCM syndrome data from 813 patients with male infertility and establish a latent tree ***: A latent tree model with a Bayesian information criterion score of-11 2.3 was *** model revealed that the characteristics of basic TCM syndromes in patients with male infertility were kidney Yang deficiency, kidney Qi deficiency,spleen Yang deficiency, liver Qi stagnation, Qi stagnation and blood stasis, and dump-heat; moreover,most patients with male infertility had complex syndromes(spleen-kidney Yang deficiency and liver Qi stagnation) rather than simple single ***: The hidden tree model analysis revealed the objective and quantitative complex relationships between the TCM symptoms of male infertility, and obtained the quantification and objective evidence of TCM syndromes in male infertility.

关键词： Infertility,male Syndromes and signs Latent tree model

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Benefits of spatial hearing to speech recognition in young people with normal hearing

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Chinese Medical Journal 2011年第24期124卷 4269-4274页

作者： SONG peng-long li Hui-jun {2. {2.-yu Department oi Otorhinolaryngology Head and Neck SurgeryFirst Affiliated Hospital Harbin Medical University HarbinHeilongjiang 150010 China Department of Otorhinolaryngology Head and Neck SurgeryBeijing Chao-Yang Hospital Capital Medical University Beijing100020 China College of Otolaryngology Capita1 Medical University Beijing100069 China Key Laboratory of Otolaryngology Head and Neck SurgeryMinistry of Education Beijing 100020 China

Background Many factors interfering with a listener attempting to grasp speech in noisy environments. The spatial hearing by which speech and noise can be spatially separated may play a crucial role in speech recognition in the presence of competing noise. This study aimed to assess whether, and to what degree, spatial hearing benefit speech recognition in young normal-hearing participants in both quiet and noisy environments. Methods Twenty-eight young participants were tested by Mandarin Hearing In Noise Test （MHINT） in quiet and noisy environments. The assessment method used was characterized by modifications of speech and noise configurations, as well as by changes of speech presentation mode. The benefit of spatial hearing was measured by speech recognition threshold （SRT） variation between speech condition 1 （SC1） and speech condition 2.（SC2.. Results There was no significant difference found in the SRT between SC1 and SC2.in quiet. SRT in SC1 was about 4.2.dB lower than that in SC2. both in speech-shaped and four-babble noise conditions. SRTs measured in both SC1 and SC2.were lower in the speech-shaped noise condition than in the four-babble noise condition. Conclusion Spatial hearing in young normal-hearing participants contribute to speech recognition in noisy environments, but provide no benefit to speech recognition in quiet environments, which may be due to the offset of auditory extrinsic redundancy against the lack of spatial hearing.

关键词： speech recognition spatial hearing speech recognition threshold speech perception

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Accuracy and repeatability of direct ciliary sulcus diameter measurements by full-scale 50-megahertz ultrasound biomicroscopy

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Chinese Medical Journal 2009年第8期122卷 955-959页

作者： li De-jiao wang {2.-li CHEN Shu li Shu-{2. MU Da-peng wang Tao Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing 100730 China Department of Ophthalmology China-Japan Friendship Hospital Beijing 100029 China

Background Phakic intraocular lens （pIOL） implantation has been a popular means for the treatment of high ametropia Measurements of ciliary sulcus diameter is important for pIOL size determining. But till now, no perfect system can directly measure it. The present study was to evaluate the accuracy, repeatability and reproducibility of direct sulcus diameter measurements obtained by a full-scale 50-megahertz （MHz） ultrasound biomicroscopy （UBM）. Methods A fresh cadaver human eye with a scale marker inserted through the posterior chamber plane from 3 o＇clock to 9 o＇clock meridian and 30 randomly selected eyes from 30 normal subjects were scanned by full-scale 50-MHz UBM in horizontal meridional scan plane. The distance between the scales and the whole length of the marker inside the cadaver eye were measured by the same observer using the ＂built-in＂ measurement tools and the indicating error of instrument was calculated. Reproducibility of the measurement was evaluated in 30 eyes by 2.operators using Blander and Altman plot test. Repeatability was evaluated from 10 successive eyes randomly selected from the 30 eyes by one operator. Results On a scale of 1 mm, the greatest indicating error was 40μm; the mean largest indicating error of 1 mm scale from the 10 images was （2._±14） μm; on a scale of 11 mm, the greatest indicating error was 70 μm; the error rate was 0.64%. The mean length of the needle inside the eye of the 10 images was 11.05 mm, with the mean indicating error of 47 μm, the average error rate was 0.43%. For ciliary sulcus diameter measurements in vivo, the coefficient of variation was 0.38%; the coefficients of repeatability for intra-observer and inter-observer measurements were 1.99% and 2.55%, respectively. The limits of agreement for intra-observer and inter-observer measurement were -0.41 mm to 0.48 mm and -0.59 mm to 0.58 mm, respectively. Conclusion The full-scale 50-MHz UBM can be a high accuracy and good repeatability means for direct measuring t

关键词： ciliary sulcus diameter ultrasound biomicroscopy accuracy repeatability and reproducibility

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Fully-exposed Pt clusters stabilized on Sn-decorated nanodiamond/graphene hybrid support for efficient ethylbenzene direct dehydrogenation

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Nano Research 2022年第12期15卷 10029-10036页

作者： linlin {2. Xuetao Qin Ting Sun Xiangbin Cai Mi peng Zhimin Jia Xiaowen Chen {2. {2. Jiangyong Diao Hongyang liu Ding Ma Department of Chemistry Northeastern UniversityShenyang110819China Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang110016China beijing National Laboratory for Molecular Engineering College of Chemistry and Molecular Engineering and College of EngineeringBIC-ESATPeking UniversityBeijing100871China Department of Physics Hong Kong University of Science and TechnologyKowloonHong Kong999077China school of Materials Science and Engineering University of Science and Technology of ChinaHefei230026China

The pursuit of energy conservation and environmental protection has always been a hot topic in the catalytic fields,which is inseparable from the rational designing of efficient catalysts and an in-depth understanding of the catalytic reaction *** this work,fully-exposed Pt clusters were fabricated on the atomically dispersed Sn decorated nanodiamond/graphene(Sn-ND@G)hybrid support and employed for direct dehydrogenation(DDH)of ethylbenzene(EB)to styrene(ST).The detailed structural characterizations revealed the fully-exposed Pt clusters were stabilized on Sn-ND@G,assisted by the spatial separation of atomically dispersed Sn *** as-prepared Pt/Sn-ND@G catalyst showed enhanced ST yield(136.2.molEB·molpt-1·h-1 EB conversion rate and 99.7%ST selectivity)and robust long-term stability at 500℃for the EB DDH reaction,compared with the traditional ND@G supported Pt nanoparticle catalyst(Pt/ND@G).The ST prefers to desorb from the fully-exposed Pt clusters,resulting in the enhanced DDH catalytic performance of the Pt/Sn-ND@G *** present work paves a new way for designing highly dispersed and stable supported metal catalysts for DDH reactions.

关键词： Pt cluster ethylbenzene dehydrogenation fully-exposed catalyst heterogeneous catalysis

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Inclusions in wrought superalloys:a review

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Journal of Iron and Steel Research International 2021年第8期28卷 921-937页

作者： Shu-feng Yang Shu-lei Yang Jing-long Qu Jin-hui Du Yu Gu peng Zhao ning {2. school of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Gaona Aero Material Co. Ltd.Beijing 100081China

Inclusions in wrought superalloys significantly affect the stability of the alloy properties and limit their use and devel-opment in aeroengines and other *** types and sources of inclusions in wrought superalloys were reviewed with analysis of the conditions of inclusion formation from the viewpoints of thermodynamics and *** ther-modynamic data for inclusion formation in nickel-based and cobalt-based alloys were summarized and *** damage of inclusions to the fatigue and tensile properties and workability of these alloys and the mechanisms of crack initiation and propagation caused by inclusions were also discussed,and the effects of inclusions with different charac-teristics on crack propagation were *** addition,the control methods and mechanisms of inclusions in the triple smelting process(vacuum induction melting+protective electroslag remelting+vacuum arc remelting)were covered,providing a reference for improving the control technology of inclusions in wrought ***,the difficulties and development trends for inclusion control in wrought superalloys were discussed.

关键词： Wrought superalloy Triple smelting Inclusion Control method

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Organic semiconductor nanostructures:optoelectronic properties,modification strategies,and photocatalytic applications

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Journal of Materials Science & Technology 2022年第18期113卷 175-198页

作者： Jiaqi Dong Chuxuan Yan Yingzhi Chen Wenjie Zhou Yu peng Yue Zhang Lu-ning {2. Zheng-Hong Huang school of Materials Science and Engineering University of Science and Technology BeijingBeijing100083China Shunde Graduate school of university of Science and Technology {2. Foshan528399China Key Laboratory of Advanced Materials(MOE) School of Materials Science and EngineeringTsinghua UniversityBeijing100084China

Organic semiconductors(OSCs)possess diverse chemical structures and tailored optoelectronic properties via simple chemical modifications,so increasing use of them are found in efficient visible-light ***,the weak chemical bonds and the poor charge behavior(e.g.,low concentration of free charge carriers,low carrier mobility)intrinsic in them,always incur quite limited stability and ***,the assembly of them into refined nanostructures or nanocomposites is usually proposed to enhance their optoelectronic properties,as well as the photocatalytic efficiency and ***-dimensional(0D)nanoparticles are low in size and hence high specific surface area(SSA);One-dimensional(1D)nanostructures are usually arranged in an orderly long range thus leading to low surface defect density and increased carrier mobility;Two-dimensional(2.)nanostructures are particularly capa-ble of enhancing the photogenerated charge utilization because of their large reaction sites and shortened charge transport ***,the building of heterogeneous interfaces in the nanocomposites can effectively facilitate the special charge *** these highlight the importance of organic nanos-tructures in improving the photocatalytic activity and ***,organic semiconductor nanostructures(OSNs)have been increasingly used in the photocatalytic water splitting into H_(2. and O_(2.,CO_(2. reduction,pollutant decomposition,disinfection,*** this review,we first examine the important optoelectronic properties of OSNs that govern the photocatalytic processes;we then analyze different classes of OSNs and their mechanistic pathways,with an emphasis on the structure-property relationships;we also introduced various photocatalytic applications of OSNs;we lastly propose the challenges and future outlook in real use.

关键词： Organic semiconductors Nanostructures Optoelectronic properties Photocatalysis

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非原发中枢神经系统非霍奇金淋巴瘤脑实质病变影像表现分析

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实用放射学杂志 2006年第1期22卷 17-19页

作者：曹崑李洁汪宁张晓鹏北京大学临床肿瘤学院北京肿瘤医院放射科北京大学临床肿瘤学院北京肿瘤医院放射科北京100036

目的探讨首发部位为非中枢神经系统的非霍奇金淋巴瘤(NHL)病例的脑实质病变影像学表现特点。方法经病理确诊为体部非霍奇金淋巴瘤,行CT和/或MR I扫描发现脑实质异常的病例8例。对所有病灶增强CT扫描及MR I表现分类分析。另取有结节强化... 详细信息

目的探讨首发部位为非中枢神经系统的非霍奇金淋巴瘤(NHL)病例的脑实质病变影像学表现特点。方法经病理确诊为体部非霍奇金淋巴瘤,行CT和/或MR I扫描发现脑实质异常的病例8例。对所有病灶增强CT扫描及MR I表现分类分析。另取有结节强化表现的其他脑转移瘤73例,与NHL病例组比较。结果CT增强扫描8例,共计病灶13个,分为①强化后低密度病灶(10/13,77%),边界均较模糊;②强化后高密度病灶(3/13,2.%),其中环形强化结节1个。所有病灶均未见与脑转移病灶有关的脑室扩张和占位效应,有强化表现的结节周围未见水肿带。行MR I检查4例中3例呈长T1长T2.号,增强后无特殊信号改变。1例呈中央长T1长T2.号,周边长T1中长T2.号,增强后周边环形强化,无水肿带。73例有结节强化表现的其他脑转移瘤中89%的病灶CT可见灶周不同程度水肿。结论本组病例中部分病灶表现不同于文献描述的NHL脑转移征象。而与其他脑转移瘤相比,周边无水肿带的结节状强化病灶也是本组病例的特殊表现之一。

关键词：淋巴瘤体层摄影术,X线计算机磁共振成像

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亚甲基四氢叶酸脱氢酶2.异质性细胞叠套结构形成的负调控分子

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中国生物化学与分子生物学报 2024年第6期40卷 819-826页

作者：冯鹏飞刘辰瑜黄一诺孙卓然张揚易黄红艳王晨曦王小宁解放军医学院研究生院北京100853 解放军总医院第二医学中心老年医学研究所衰老与相关疾病研究北京市重点实验室国家老年疾病临床医学研究中心北京100853 军事医学研究院生物工程研究所北京100071 首都医科大学附属北京世纪坛医院肿瘤治疗性疫苗北京市重点实验室北京100038

异质性细胞叠套结构(heterotypic cell-in-cell structure,heCICs)介导独特的非自主性细胞死亡,广泛参与肿瘤发生、发展和临床预后等多种重要的病理学过程。亚甲基四氢叶酸脱氢酶2.methylenetetrahydrofolata dehydrogenase 2.MTHFD2.作为一碳代谢的关键酶之一,在多种肿瘤细胞中高表达。在本研究中,为了探究MTHFD2.heCICs形成能力的影响,首先应用活细胞染料对肝癌细胞和免疫细胞分别进行标记,利用荧光显微镜对细胞进行拍摄分析建立heCICs模型。进一步通过RNAi技术瞬时敲低细胞中的MTHFD 2.结果显示,MTHFD 2.低后,PLC/PRF/5和Hep3B分别与免疫细胞形成heCICs的能力显著升高(均P1)。通过同源重组方法构建MTHFD2.组表达质粒,进一步构建MTHFD2.表达细胞系;将过表达细胞系与免疫细胞共培养检测MTHFD2.表达对heCICs形成能力的影响,结果显示,过表达MTHFD2.heCICs形成率显著降低(均P1)。综上,本研究表明,MTHFD2.heCICs形成的负调控因子,为靶向MTHFD2.进heCICs形成增强免疫细胞胞内杀伤提供了研究基础。

关键词：亚甲基四氢叶酸脱氢酶2 异质性细胞叠套结构肝癌免疫治疗

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Discovery of Cosmic Spherules from the Mesoproterozoic Strata and its Significance——in Case of the Ming Tombs Area, beijing

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Acta Geologica Sinica(English Edition) 2020年第1期94卷 38-56页

作者： SONG Tianrui ZHENG ning liU Yongqing KUANG Hongwei {2. Nan li Chao TANG Jigang YAN Qinggao GAO linzhi ZHU Zhicai XIA Xiaoxu {2. Yuchong Institute of Geology Chinese Academy of Geological SciencesBeijing 100037China National Research Center of Geoanalysis Beijing 100037China Faculty of Land Resource Engineering Kunming University of Science and TechnologyKunming 650093YunnanChina beijing General Research Institute of Mining and Metallurgy Beijing 100044China

This study covers cosmic spherules derived from the Mesoproterozoic Dahongyu Formation in the Ming Tombs area, beijing. The cosmic spherules include iron oxide cosmic spherules, carbonaceous chondrites, and atomic iron "steely bead"-shaped cosmic spherules. The mineral assemblage of silicon carbide, forsterite, zircon, and glass spherules and fragments were picked from melt-silicified carbonate of the Mesoproterozoic Dahongyu Formation(ca. 162. Ma). Cosmic spherule assemblages are solely discovered from sedimentary rocks in China. Platinum group elements(PGE) were determined for the first time in cosmic spherules and associated minerals. PGE comparative observation between meteorite and cosmic spherules is presented in this study. It is recognized that an extraterrestrial meteorite impact event might have occurred in the Dahongyu Stage. The main evidence is a large number of iron cosmic spherules in silicified oncolitic limestone, and associated cosmic silicon carbide, glass spherules, and fragments, as well as the presence of forsterite. The impact-volcanic crater is characteristic of a big black shale block dropped into the bended silicified limestone.

关键词： cosmic spherules carbonaceous chondrite meteorite PGE Proterozoic strata beijing impact event

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