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Journal of Geodesy and Geoinformation Science 2024年第2期7卷 80-94页

作者： LIU Dingming DU Jiusheng wang Yu yang junping school of Surveying and Land Information Engineering Henan Polytechnic UniversityJiaozuo 454003China

This study utilized census data from Henan Province for the years 2000,2010,and 2020 to investigate the spatiotemporal evolution of population aging,defined by the proportion of the population aged 65 and *** spatial analysis techniques such as spatial autocorrelation and the standard deviation ellipse,the research mapped out the progression and distribution of aging ***,the study delved into the influencing factors of aging using an optimal parameters-based geographical *** indicate a deepening degree of population aging in Henan Province,transitioning from an adult type to an old type *** is a marked positive spatial correlation among counties,with high-value aging areas initially decreasing,then increasing,and notably spreading from the central to the central and southern regions of the *** center of gravity for population aging,specifically around changge city and Xuchang city,exhibits a trajectory moving southeast before shifting *** detection reveals that in 2000,2010,and 2020,the elderly dependency ratio predominantly influences the aging trend,with explanatory powers of 88.4%,87.9%,and 90.9%,*** analysis indicates that the interaction between the old-child ratio and the elderly dependency ratio has a strong explanatory power for the aging patterns in Henan Province,reaching 97.3%,97.0%,and 97.4%,respectively.

关键词： population aging spatial pattern evolution spatial autocorrelation influencing factors optimal parameters-based geographical detector

coupled funnel control for supersonic tailless aerial vehicle on penetrating counter air

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chinese Journal of Aeronautics 2024年第7期37卷 458-481页

作者： Yingyang wang Peng ZHANG Jilian GUO jianbo HU Equipment Management and Unmanned Aerial Vehicle Engineering school Air Force Engineering UniversityXi’an 710051China Aviation Engineering school Air Force Engineering UniversityXi’an 710038China

Supersonic Tailless Aerial Vehicles(STAVs)will become an essential force in Penetrating counter Air(PcA),but STAVs do not have the traditional horizontal and vertical tails,making pitch and yaw control *** attack angle and the sideslip angle need to be limited to ensure that the engine inlet and the aerodynamic rudder at the rear of the vehicle can work properly,which is the so-called security *** addition,the tracking error of the aerodynamic angle needs to be limited to achieve effective attitude control or high-accuracy tracking of trajectories,which is the so-called performance *** this end,an attitude control method that meets the needs of PcA has been devised,based on constraint definition,coupled constraints handling,and control law ***,mathematical descriptions of the security constraints,performance constraints,and control constraints are ***,two treatment methods,coupled command filter and coupled funnel control are proposed for the aerodynamic angle coupled constraint ***,based on Nonlinear Dynamic Inverse(NDI)design,the coupled funnel controller is designed and validated by simulation for two typical mission scenarios,high-altitude penetration and low-altitude surprise *** proposed control method not only satisfies the security and performance constraints of STAV attitude control but also is highly robust.

关键词： Supersonic tailless aircraft Penetrating counter air Funnel control Attitude control control allocation

behaviors analysis of on-coming cluster based on knowledge under cluster security requirements

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cHINESE JOURNAL OF AERONAUTIcS 2024年第9期37卷 448-462页

作者： Zhang, huixia Liang, Yan Shi, Ying wang, Yuedong Ma, chaoxiong wang, Ran Northwestern Polytech Univ Sch Automat Xian 710129 Peoples R China Minist Educ Key Lab Informat Fus Technol Xian 710129 Peoples R China

Analysis of cluster behaviors of the on-coming cluster is an essential measure for high value locations on the battlefield. Unlike target tracking and clustering analysis, cluster behaviors analysis under cluster security requirements remains an open issue, which is a joint analysis of clustering, intent reasoning and activity regions. To address this issue, a framework for cluster behaviors analysis is proposed by incorporating expert knowledge and domain knowledge, and a knowledge-assisted score function with is designed to improve the accuracy of intent reasoning network, overcoming the effects of possible knowledge errors. The framework consists of three modules for cluster analysis, intent reasoning and activity region analysis for typical tasks, in which an intent reasoning network is constructed to obtain cluster intents by using a hybrid knowledge and data driven approach. Furthermore, considering the complexity of the battlefield environment, different tasks and corresponding activity region optimization functions are designed for cluster activity region analysis, which are vital elements of cluster behaviors analysis. Simulations demonstrate the effectiveness of the proposed cluster behaviors analysis framework. (c) 2024 Production and hosting by Elsevier Ltd. on behalf of chinese Society of Aeronautics and Astronautics. This is an open access article under the cc bY-Nc-ND license (http://***/ licenses/by-nc-nd/4.0/).

关键词： cluster analysis Intent reasoning Activity region analysis cluster behavior battlefield environment SYSTEMS

Framework and Key Technologies of Human-machine Hybrid-augmented Intelligence System for Large-scale Power Grid Dispatching and control

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cSEE Journal of Power and Energy Systems 2024年第1期10卷 1-12页

作者： Shixiong Fan jianbo Guo Shicong Ma Lixin Li Guozheng wang Haotian Xu Jin yang Zening Zhao china Electric Power Research Institute Beijing 100192China the beijing Huairou Laboratory Beijing 101400China school of Engineering the University of GlasgowGlasgow G128QQUK

With integration of large-scale renewable energy,new controllable devices,and required reinforcement of power grids,modern power systems have typical characteristics such as uncertainty,vulnerability and openness,which makes operation and control of power grids face severe security *** of artificial intelligence(AI)technologies represented by machine learning in power grid regulation is limited by reliability,interpretability and generalization ability of complex *** of hybrid-augmented intelligence(HAI)based on human-machine collaboration(HMc)is a pivotal direction for future development of AI technology in this *** on characteristics of applications in power grid regulation,this paper discusses system architecture and key technologies of human-machine hybrid-augmented intelligence(HHI)system for large-scale power grid dispatching and control(PGDc).First,theory and application scenarios of HHI are introduced and analyzed;then physical and functional architectures of HHI system and human-machine collaborative regulation process are *** technologies are discussed to achieve a thorough integration of human/machine ***,state-of-theart and future development of HHI in power grid regulation are summarized,aiming to efficiently improve the intelligent level of power grid regulation in a human-machine interactive and collaborative way.

关键词： Artificial intelligence human-machine collaborative control human-machine hy brid intelligence optimization and evolution power grid dispatching and control

Metal complex catalysts broaden bioorthogonal reactions

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Science china chemistry 2024年第2期67卷 428-449页

作者： Hanjie Zhang Xiaoyu Qin junping wang Li Ma Tianfeng chen Department of chemistry Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and ApplicationsJinan UniversityGuangzhou510632China

bioorthogonal reactions involving transition metals have diversified applications in imaging,drug development,chemical catalysis and other *** metals used to catalyze the bioorthogonal reaction mainly include ruthenium,palladium,copper,and ***,the great potential for translational applications of bioorthogonal reaction needs to be further expanded and their reaction efficiency should be ***,it is an urgent need for the development of this field to find more suitable catalysts to efficiently catalyze existing biological orthogonal reactions and expand the types of biological orthogonal ***,this review not only summarizes those transition metal complexes-based catalysts participating in bioorthogonal reaction and some bioorthogonal reactions involving transition metals inside the cells,but also sheds light into the discovery of new transition metal complexes and their future development in applications.

关键词： transition metal complexes bioorthogonal reactions biological applications

MiR-4465-modified mesenchymal stem cell-derived small extracellular vesicles inhibit liver fibrosis development via targeting LOXL2 expression

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Journal of Zhejiang University-Science b(biomedicine & biotechnology) 2024年第7期25卷 594-604页

作者： Yanjin wang Yifei cHEN Fuji yang Xiaolong YU Ying cHU Jing ZHOU Yongmin YAN jianbo XI Department of Laboratory Medicine Wujin Hospital Affiliated with Jiangsu UniversityJiangsu UniversityChangzhou 213017China Department of Laboratory Medicine School of MedicineJiangsu UniversityZhenjiang 212013China changzhou Key Laboratory of Molecular Diagnostics and Precision cancer Medicine Wujin Clinical College of Xuzhou Medical UniversityChangzhou 213017China

Liver fibrosis is a significant health burden,marked by the consistent deposition of ***,the currently available treatment approaches for this condition are far from *** oxidase-like protein 2(LOXL2)secreted by hepatic stellate cells(HScs)is a crucial player in the cross-linking of matrix collagen and is a significant target for treating liver *** stem cell-derived small extracellular vesicles(MSc-sEVs)have been proposed as a potential treatment option for chronic liver *** studies have found that MSc-sEV can be used for microRNA delivery into target cells or *** is currently unclear whether microRNA-4465(miR-4465)can target LOXL2 and inhibit HSc ***,it is uncertain whether MSc-sEV can be utilized as a gene therapy vector to carry miR-4465 and effectively inhibit the progression of liver *** study explored the effect of miR-4465-modified MSc-sEV(MSc-sEVmiR-4465)on LOXL2 expression and liver fibrosis *** results showed that miR-4465 can bind specifically to the promoter of the LOXL2 gene in ***,MSc-sEVmiR-4465 inhibited HSc activation and collagen expression by downregulating LOXL2 expression in ***-sEVmiR-4465 injection could reduce HSc activation and collagen deposition in the ccl4-induced mouse ***-sEVmiR-4465 mediating via LOXL2 also hindered the migration and invasion of HepG2 *** conclusion,we found that MSc-sEV can deliver miR-4465 into HSc to alleviate liver fibrosis via altering LOXL2,which might provide a promising therapeutic strategy for liver diseases.

关键词： Mesenchymal stem cell(MSc) Small extracellular vesicle(sEV) MicroRNA-4465(miR-4465) Hepatic stellate cell(HSc) Liver fibrosis

In-situ AFM and quasi-in-situ studies for localized corrosion in Mg-9Al-1Fe-(Gd) alloys under 3.5 wt.% Nacl environment

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Journal of Magnesium and Alloys 2024年第3期12卷 1170-1185页

作者： junping Shen Tao Lai Zheng Yin yang chen Kun wang Hong Yan Honggun Song Ruiliang Liu chao Luo Zhi Hu school of Advanced Manufacturing Nanchang UniversityNanchang 330031China Institute for Advanced Study Nanchang UniversityNanchang 330031China Singapore centre for Environmental Life Sciences Engineering Nanyang Technological University60 Nanyang Drive 637751Singapore

Revealing the localized corrosion process of Mg alloy is considered as one of the most significant ways for improving its corrosion *** reliable monitor should be high distinguishability and real-time in liquid ***,Mg-9Al-1Fe and Mg-9Al-1Fe-1Gd alloys were designed to highlight the impact of intermetallic on the corrosion ***-situ AFM with a special electrolyte circulation system and quasi-in-situ SEM observation were used to monitor the corrosion process of the designed ***-EDS and TEM-SAED were applied to identify the intermetallic in the designed alloys,and their volta potentials were measured by *** to the real-time and real-space in-situ AFM monitor,the corrosion process consisted of dissolution of anodicα-Mg phase,accumulation of corrosion products around cathodic phase and shedding of some fine cathodic ***,the localized corrosion process of Mg alloy was revealed combined with the results of the monitor of corrosion process and Volta potential difference.

关键词： Magnesium Localized corrosion In-situ AFM SKPFM corrosion behaviour.

Atomic tracking of thermally-driven structural evolution in 2D crystals:case of NbSe_(2)

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InfoMat 2024年第2期6卷 90-98页

作者： baofei Hou Teng Zhang Tingting wang Hongyan Ji huixia yang Liangguang Jia Xu Han Jingsi Qiao Yu Zhang Liwei Liu Hong-Jun Gao Yeliang wang school of Integrated circuits and Electronics&yangtze Delta Region Academy Beijing Institute of TechnologyBeijingthe People's Republic of China Institute of Physics Chinese Academy of SciencesBeijingthe People's Republic of China

Advanced atomic tracking techniques play a critical role in characterizing structural evolution,elucidating fundamental mechanisms of exotic phenomena and tailoring delicate *** driven structural modulation in 2D crystals,such as the charge density wave(cDW),often leads to intriguing quantum properties,making them a valuable platform for exploring fundamental physics and potential device ***,despite their significance,experimental studies addressing atomic tracking of thermally-driven structural evolution in 2D crystals have been ***,we utilize high-accuracy variable-temperature atomic tracking measurements with scanning tunneling microscopy(STM)to directly observe a series of structural transitions in a model 2D crystal,namely NbSe_(2).With the atomic tracking technique,we confirm the existence of the universal thermally-driven cDW transition hysteresis between the heating and cooling *** transition hysteresis,characterized by a constant temperature offset,represents a new phenomenon of structural *** findings provide a feasible method to track cDW transitions at the atomic scale in 2D crystals,significantly contributing to a better understanding and the potential modulation of these materials'functions in nanodevices.

关键词： 2D crystal atomic tracking technique structural evolution temperature hysteresis

A method to determine the bonded-particle model parameters for simulation of ores

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Particuology 2024年第3期86卷 24-38页

作者： Shuwei Wu Guoqiang wang Longfei Fan Wei Guan jianbo Guo Zhengbin Liu Yukuan wang school of Mechanical and Aerospace Engineering Jilin UniversityChangchun130025China

The bonded-particle model(bPM)is commonly used in the numerical analysis of ore *** improve the accuracy of simulating the mechanical process of ore process of ore crushing in a crusher,the parameters of the bPM for the ore must be *** this study,a calibration method was proposed for the scientific determination of the parameters of the bPM for ore undergoing uniaxial ***,physical tests and simulations were conducted to determine the mechanical response(uniaxial compressive strength and macroscopic stiffness)of ore during uniaxial ***,the sensitivity of the mechanical response to the values of microscopic parameters was tested using a Plackett-burman ***,the microscopic parameters with the greatest impact on the response were identified,and the range of parameters that met the target response was determined using a steepest ascent design;Second,a second-order model of the mechanical response was established using the sensitive parameters by combining a box-behnken design with response surface methodology to obtain the optimal bPM *** tests showed that the normal stiffness per unit area,critical shear stress,and bonded disk radius had significant effects on the uniaxial compressive strength(UcS)and macroscopic stiffness(MS).To verify the validity of the proposed calibration method,laboratory tests were *** consistency of the simulation results with experimental results indicated that response surface methodology with the Plackett-burman design,steepest ascent design,and box-behnken design can be an effective method for calibrating the bPM of ores.

关键词： bonded-particle model Discrete element method calibration method Design of experiment Uniaxial compression test