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食管裂孔疝患者行无痛胃镜检查并发肺炎5例并文献复习

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山东大学学报（医学版） 2024年第1期62卷 71-75页

作者：陈文军宋丽君王俊娟青岛大学附属威海市立第二医院消化内科山东威海264200

目的探讨食管裂孔疝患者行无痛胃镜检查并发肺炎的诊疗及预防措施。方法选取2021年11月至2023年2月青岛大学附属威海市立第二医院收治的行无痛胃镜检查并发肺炎的食管裂孔疝患者5例,回顾性分析其临床特点、诊治过程,并复习相关文献。结... 详细信息

目的探讨食管裂孔疝患者行无痛胃镜检查并发肺炎的诊疗及预防措施。方法选取2021年11月至2023年2月青岛大学附属威海市立第二医院收治的行无痛胃镜检查并发肺炎的食管裂孔疝患者5例,回顾性分析其临床特点、诊治过程,并复习相关文献。结果5例患者中有4例在进镜过程中发现食管中有液体潴留。5例患者均发热,其他表现有咳嗽、咳痰、畏寒等;白细胞总数或者中性粒细胞比例均升高;胸部CT均显示左肺炎症。5例患者中,4例术中给予吸氧及静脉应用地塞米松;4例给予左氧氟沙星抗感染,1例给予头孢唑肟钠抗感染治疗。5例患者体温均于48 h内恢复正常,4例经CT复查显示病灶吸收,1例患者CT随访发现左肺出现厚壁空洞,经延长抗感染治疗后空洞消失,病灶吸收。结论食管裂孔疝患者行无痛胃镜检查并发肺炎应在临床上高度重视并积极采取防治措施。

关键词：食管裂孔疝无痛胃镜误吸肺炎

Effects of anti-CD4 antibody treatment on calcium ions influx in peanut-sensitized C3H/HeJ mice

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Food Science and Human Wellness 2023年第3期12卷 765-773页

作者： junjuan wang Cui Zhou Shiwen Han Zainabu Majid Na Sun Huilian Che Key Laboratory of Precision Nutrition and Food Quality Key Laboratory of Functional DairyMinistry of EducationCollege of Food Science and Nutritional EngineeringChina Agricultural UniversityBeijing 100083China School of Public Health Capital Medical UniversityBeijing 100069China National Engineering Research Center of Seafood School of Food Science and TechnologyDalian Polytechnic UniversityDalian 116034China

The precise mechanism underlying the effects of anti-CD4 antibody and calcium ions(Ca^(2+)) in peanut allergy remains unknown.C3 H/HeJ mice sensitized with peanut protein extract(PPE)were injected with anti-CD4 antibodies for 4 *** with PPE increased the specific immunoglobulin E(IgE),cytokine,histamine,and mMcp-1 levels,upregulated decorin(Dcn)expression,induced Ca^(2+) inflow in the spleen,and augmented the expression of the transcription factors GATA-3 and Foxp3,which resulted in Th2 and Treg cell ***,the Ca^(2+) levels were positively correlated with the histamine,interleukin(IL)-4,IL-5,and IL-13 levels,and negatively correlated with IL-10 ***,administration of anti-CD4 antibodies markedly alleviated allergic symptoms,activated T cells,and reduced Ca^(2+) inflow,cytokine,histamine,mMcp-1,and the IgHG3,CXCLI2,MMP2 and FABP4 *** results indicated that anti-CD4 antibodies can ameliorate PPE-induced allergy,which is probably related to the suppression of Ca^(2+) inflow,and inhibiting histamine,cytokine and IgHG3,CXCL12,MMP2,and FABP4,thus exerting a protective effect against PPEsensitized food allergy.

关键词： Calcium ions Anti-CD4 C3H/HeJ mice Peanut Allergy

Meta-Analysis:Prevalence of Food Allergy and Food Allergens—China, 2000−2021

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China CDC weekly 2022年第34期4卷 766-770,I0003-I0005页

作者： Jiangzuo Luo Qiuyu Zhang Yanjun Gu junjuan wang Guirong Liu Tao He Huilian Che Key Laboratory of Precision Nutrition and Food Quality Key Laboratory of Functional DairyMinistry of EducationCollege of Food Science and Nutritional EngineeringChina Agricultural UniversityBeijingChina

What is already known about this topic?In recent decades,the prevalence of food allergy has increased worldwide;however,a comprehensive estimate of the prevalence of food allergy and allergens in China is not yet *** is added by this report?By searching the English databases PubMed,Embase,Cochrane Library,and Chinese databases CNKI,Wanfang Data,and VIP Chinese epidemiological studies on food allergy,the probability of food allergy in China and related influencing factors were *** are the implications for public health practice?The findings of this study provide up-to-date estimates of the prevalence of food allergy rates in China in terms of age,gender,and the eight major food allergens.

关键词： has searching gender

Construction of metallo-complexes with 2,2′:6′,2″-terpyridine substituted triphenylamine in different modified positions and their photophysical properties

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Chinese Chemical Letters 2024年第7期35卷 301-305页

作者： Shengwen Guan Zhaotong Wei Ningxu Han Yude Wei Bin Xu Ming wang junjuan Shi State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012China

The stable coordinated metallo-complexes based on 2,2′:6′,2″-terpyridine(tpy)and its derivatives have been widely researched for various wide-ranging applications in photoelectronics,catalysis,sensor,photoluminescence,and so ***,the most reported studies ignored the comprehensive comparison between structures modified by different positions and ***,we design a series of metallo-complexes which were assembled with tpy substituted triphenylamine(TPA)at different positions and metal ions and explored their photophysical *** the solution state,MLE_(2)based on the 5,5″-positions modification showed the highest PLQYs and PL *** the increase of solvent polarity,MLB2exhibit the largest *** the solid state,from MLA_(2)to MLE_(2),the emission colours are gradually red-shifted from yellow to *** findings in this work may pave a new way to design functional metallo-complexes,not just for PL properties.

关键词： Metallo-complexes 2,2′:6′,2″-terpyridine Triphenylamine Different modified positions Photophysical properties

Characters and structures of the nucleobase-ascorbate transporters(NAT)family genes in Gossypium hirsutum and their roles in responding to salt and drought stresses

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Journal of Cotton Research 2022年第2期5卷 115-129页

作者： GUO Lixue ZHAO Lanjie LU Xuke CHEN Xiugui wang Shuai wang junjuan wang Delong YIN Zujun CHEN Chao FAN Yapeng ZHANG Yuexin YE Wuwei State Key Laboratory of C otton Biology/I nstitute of Cott on Research of Chinese Academy of Agricultural Sciences/Zhengzhou Research Base School of Agricultural SciencesZhengzhou University/Key Laboratory for Cotton Genetic ImprovementMOARAAnyang 455000HenanChina

Background: Nucleobase-ascorbate transporters(NAT), synonymously called nucleobase-cation symporter 2(NCS2) proteins, were earlier reported to be involved in plant growth, development and resistance to stress. Previous studies concluded that s a polymorphic SNP associated with NAT12 was significant di erent between salt-tolerant and salt-sensitive materials of upland cotton. In current study, a comprehensive analysis of NAT family genes was conducted for the first time in ***: In this study, we discovered 32, 32, 18, and 16 NAT genes in Gossypium hirsutum, G. barbadense, G. raimondii and G. arboreum, respectively, which were classified into four groups(groups I–IV) based on the multiple sequence analysis. These GhNAT genes were unevenly distributed on At and Dt sub-genome in G. hirsutum. Most GhNAT members in the same group had similar gene structure characteristics and motif composition. The collinearity analysis revealed segmental duplication as well as tandem duplication contributing to the expansion of the GhNATs. The analysis of cis-acting regulatory elements of GhNATs showed that the function of GhNAT genes in cotton might be related to plant hormone and stress response. Under di erent conditions, the expression levels further suggested the GhNAT family genes were associated with plant response to various abiotic stresses. GhNAT12 was detected in the plasma membrane. And it was validated that the GhNAT12 gene played an important role in regulating cotton resistance to salt and drought stress through the virus-induced gene silencing(VIGS) ***: A comprehensive analysis of NAT gene family was performed in cotton, including phylogenetic analysis, chromosomal location, collinearity analysis, motifs, gene structure and so on. Our results will further broaden the insight into the evolution and potential functions of NAT genes in cotton. Current findings could make significant contribution towards screening more candidate genes related to b

关键词： Gossypium hirsutum NAT gene family VIGS Salt and drought stresses

海岛棉耐盐相关基因GbPLA1-32的克隆及生物信息学分析

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分子植物育种 2024年第5期22卷 1421-1429页

作者：张红张悦新徐楠芮存范亚朋王晶韩明格王琴琴孙亮庆陈修贵陆许可王俊娟王德龙王帅郭丽雪赵兰杰陈超陈全家叶武威新疆农业大学农学院教育部棉花工程研究中心乌鲁木齐830052 中国农业科学院棉花研究所棉花生物学国家重点实验室郑州大学研究基地农业部棉花遗传改良重点开放实验室安阳455000

为了解海岛棉GbPLA1-32基因结构特征及功能,本研究以海岛棉‘海7124’为实验材料,利用前期耐盐转录组测序结果筛选得到差异表达基因并进行克隆。通过生物信息学分析,获得‘海7124’GbPLA1-32基因全长CDS,分析该基因编码蛋白的理化性质... 详细信息

为了解海岛棉GbPLA1-32基因结构特征及功能,本研究以海岛棉‘海7124’为实验材料,利用前期耐盐转录组测序结果筛选得到差异表达基因并进行克隆。通过生物信息学分析,获得‘海7124’GbPLA1-32基因全长CDS,分析该基因编码蛋白的理化性质、鉴定其亲水性与疏水性,对磷酸化和糖基化位点、信号肽和跨膜区以及蛋白质结构进行预测,确定亚细胞定位并构建系统进化树。结果表明,该基因编码区全长1530 bp,编码509个氨基酸,编码蛋白在磷脂酶A1家族,属α/β-水解酶超家族。它属于亲水性蛋白,不存在明显信号肽且不具有跨膜结构,亚细胞定位于叶绿体中。同时,α-螺旋、延伸链、β-转角和无规则卷曲这4个元件构成了Gb PLA1-32蛋白的二级结构。进化树分析表明海岛棉与陆地棉亲缘关系最为接近,根据其编码蛋白将该基因命名为GbPLA1-32。RT-qPCR分析结果表明,GbPLA1-32基因能够对PEG和盐两种胁迫做出响应。本研究结果可为进一步阐明GbPLA1-32在海岛棉中的生物学功能提供参考。

关键词：海岛棉磷脂酶A1 基因克隆表达分析生物信息学分析

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早熟棉花品种湘棉早3号

中国棉花 2024年第8期51卷 47-48,51,F0002页

作者：王俊娟王帅彭凡嘉王德龙陆许可阴祖军陈修贵郭丽雪赵兰杰陈超叶武威中国农业科学院棉花研究所/棉花生物育种及产业技术国家工程研究中心/农业农村部棉花遗传改良重点开放实验室河南安阳455000 湖南省棉花科学研究所湖南常德415101

湘棉早3号于2022年4月通过湖南省农作物品种审定委员会审定,2023年5月获得植物新品种权授权。该品种为非转基因早熟常规棉品种,2020年湖南省早熟棉生产试验中平均每666.7 m^(2)皮棉产量为93.3 kg,比对照省工棉2号增产3.9%。概述了湘棉早... 详细信息

湘棉早3号于2022年4月通过湖南省农作物品种审定委员会审定,2023年5月获得植物新品种权授权。该品种为非转基因早熟常规棉品种,2020年湖南省早熟棉生产试验中平均每666.7 m^(2)皮棉产量为93.3 kg,比对照省工棉2号增产3.9%。概述了湘棉早3号的选育经过、特征特性、适宜种植区域,并总结了其关键栽培技术。

关键词：棉花湘棉早3号品种选育早熟适应性

Functional structure analysis and genome‑wide identification of CNX gene family in cotton

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Journal of Cotton Research 2022年第3期5卷 285-301页

作者： XU Nan ZHANG Hong ZHANG Yuexin FAN Yapeng wang Jing MALIK Waqar Afzal RUI Cun HAN Mingge LU Xuke CHEN Xiugui wang junjuan wang Delong wang Shuai CHEN Chao GUO Lixue ZHAO Lanjie YE Wuwei Institute of Cotton Research of Chinese Academy of Agricultural Sciences/Zhengzhou Research Base State Key Laboratory of Cotton Biology/School of Agricultural SciencesZhengzhou UniversityAnyang 455000HenanChina

Background:Under abiotic stress conditions,cotton growth is inhibited and yield losses are *** of calnexin family members and function analysis under abiotic stress laid the foundation for the screening of stressrelated candidate ***:A total of 60 CNX family members have been identified in Gossypium hirsutum,***,***,and ***,and they were divided into two categories:CNX and CRT *** the construction of a phylogenetic tree,they were subdivided into three *** analysis of chromosome localization,conserved promoters,gene structure and selection under pressure showed that the family members were highly conserved in the evolution *** of cis-acting elements in the promoter regions showed that CNX family genes contain regulatory elements for growth and development,anaerobic,drought,defense and stress response,and plant *** RNA-seq data to study the expression pattern of GhCNX genes under cold,hot,salt stress and Polyethylene glycol,it was observed that the gene expression levels changed by different degrees under different stress conditions,indicating that GhCNX members were involved in the regulation of multiple biological ***:This study provides an insight into the members of cotton CNX *** results of this study suggested that CNX family members play a role in defense against adversity and provide a foundation for the discovery of stress-related genes.

关键词： Calnexin GhCNX Conserved motifs Selection pressure Collinearity Differential expression

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基于监测预警的小麦赤霉病药剂防治效果评价

现代农业科技 2024年第4期 50-53页

作者：倪运东刘美艳王军娟顾冬玫徐璟仪李小华于湧鑫李赟黄卫利淮安市洪泽区植物保护站江苏淮安223100 江苏师范大学生命科学学院江苏徐州221116 淮安市洪泽区气象局江苏淮安223100 西安黄氏生物工程有限公司陕西西安710065

2022—2023年,在淮安市洪泽区进行小麦赤霉病自动监测预警系统的试验示范,并以监测预警系统的预测结果为指导开展田间药剂复配试验,以期确定最佳的喷施次数、药剂组合和药剂用量,指导大田小麦赤霉病的防控。结果表明,200 g/L氟唑菌酰羟... 详细信息

2022—2023年,在淮安市洪泽区进行小麦赤霉病自动监测预警系统的试验示范,并以监测预警系统的预测结果为指导开展田间药剂复配试验,以期确定最佳的喷施次数、药剂组合和药剂用量,指导大田小麦赤霉病的防控。结果表明,200 g/L氟唑菌酰羟胺悬浮剂(麦甜)900 mL/hm^(2)+250 g/L丙环唑乳油(麦甜伴侣)600 mL/hm^(2)+22%噻虫·高氯氟微囊悬浮-悬浮剂150 mL/hm^(2)+益施多金750 mL/hm^(2)二次施药是防治小麦赤霉病的最优药剂组合与用量,对小麦赤霉病的病指防效达到85.28%。

关键词：小麦赤霉病自动监测预警系统发病率复配农药防治效果