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Research on Flexible Job Shop Scheduling Based on Improved Two-Layer Optimization Algorithm

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Computers, Materials & Continua 2024年第1期78卷 811-843页

作者： Qinhui Liu Laizheng Zhu Zhijie Gao jilong wang Jiang Li College of Mechanical and Electrical Engineering Harbin Engineering UniversityHarbin150001China

To improve the productivity,the resource utilization and reduce the production cost of flexible job shops,this paper designs an improved two-layer optimization algorithm for the dual-resource scheduling optimization problem of flexible job shop considering workpiece ***,a mathematical model is established to minimize the maximum completion ***,an improved two-layer optimization algorithm is designed:the outer layer algorithm uses an improved PSO(Particle Swarm Optimization)to solve the workpiece batching problem,and the inner layer algorithm uses an improved GA(Genetic Algorithm)to solve the dual-resource scheduling ***,a rescheduling method is designed to solve the task disturbance problem,represented by machine failures,occurring in the workshop production ***,the superiority and effectiveness of the improved two-layer optimization algorithm are verified by two typical *** case results show that the improved two-layer optimization algorithm increases the average productivity by 7.44% compared to the ordinary two-layer optimization *** setting the different numbers of AGVs(Automated Guided Vehicles)and analyzing the impact on the production cycle of the whole order,this paper uses two indicators,the maximum completion time decreasing rate and the average AGV load time,to obtain the optimal number of AGVs,which saves the cost of production while ensuring the production *** research combines the solved problem with the real production process,which improves the productivity and reduces the production cost of the flexible job shop,and provides new ideas for the subsequent research.

关键词： Dual resource scheduling workpiece batching rescheduling particle swarm optimization genetic algorithm

Characteristics and influencing factors of CO_(2) emission from inland waters in China

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Science China Earth Sciences 2024年第6期67卷 2034-2055页

作者： Ting ZHOU Xiaofeng wang Zuolin XIAO Zhaoyin QING Xianxiang LI jilong wang Ziyi QUE Chongqing Key Laboratory of Carbon Cycling and Carbon Regulation in Mountainous Ecosystems Chongqing 401331China School of Geography and Tourism Chongqing Normal UniversityChongqing 401331China Chongqing Field Observation and Research Station of Earth Surface Ecological Processes in Three Gorges Reservoir Area Chongqing 405400China School of Earth System Science Tianjin UniversityTianjin 300072China

Inland water bodies,being the most active biogeochemical cycle reactors,play a pivotal role in the global carbon cycle and CO_(2) *** study integrates existing observation dataset of CO_(2) flux(fCO_(2))in rivers,lakes and reservoirs in China,to elucidate their spatial-temporal patterns and key influencing factors and to reappraise the significance for regional carbon *** showed that,the fCO_(2) in rivers,lakes and reservoirs in China presented significant variability with large range of-379.3-4947.6,-160.1-785.0 and -74.0-1603.1 mg CO_(2)m-2h^(-1),*** median of the fCO_(2) in rivers was of 228.5 mg CO_(2)m^(-2)h^(-1),observably higher than these in lakes and reservoirs(26.0 and 28.3 mg CO_(2)m^(-2)h^(-1),respectively).The fCO_(2)in rivers and reservoirs exhibited similar decreasing trend from south to north as a result of universal climate restraint,the averaged fCO_(2) in Pearl River and Yangtze River basins showed much higher than that in Northeastern ***,the averaged fCO_(2) in the Mongolia-Xinjiang lake district and the Northeast lake district were higher than other lake districts,followed by the Qinghai-Xizang lake district,and the Eastern and Yungui lake district were generally low,contradicting the climatic *** water primary production enhancement resulting from human activities was the main driver of spatial variation in the fCO_(2) in ***,the fCO_(2) in rivers presented seasonal pattern with higher wet season than dry season,while opposite patterns were found in lakes and *** temperature,precipitation and water primary production were main ***,it showed pH was a key factor indicating the variability of the fCO_(2) levels either in rivers,lakes or in *** lakes,the fCO_(2) is closely linked to chlorophyll a(Chl-a)and dissolved oxygen(DO),whereas,the fCO_(2) in rivers is primarily associated with organic carbon(OC)and total nitrogen(TN),highlighting the dive

关键词： Rivers/lakes/reservoirs CO_(2) emission Spatio-temporal variability Influence factors Regional contribution

Mitogenomic phylogeny,biogeography,and cryptic divergence of the genus Silurus(Siluriformes:Siluridae)

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Zoological Research 2024年第4期45卷 711-723页

作者： Weitao Chen Nicolas Hubert Yuefei Li Shuli Zhu Jun wang Denggao Xiang Shang Gao Chunni Kou jilong wang Tai wang Zhiqiang Liang Junjie Wu Xinhui Li Jie Li Pearl River Fisheries Research Institute Chinese Academy of Fishery SciencesGuangzhouGuangdong 510380China China Key Laboratory of Aquatic Animal Immune Technology of Guangdong Province GuangzhouGuangdong 510380China Key Laboratory of Prevention and Control for Aquatic Invasive Alien Species Ministry of Agriculture and Rural AffairsGuangzhouGuangdong 510380China Scientific Observing and Experimental Station of National Fisheries Resources and Environment GuangzhouGuangdong 510380China Institut de Recherche pour le Développement MontpellierUMR 226 ISEM(UM-CNRS-IRD)France State Key Laboratory of Eco-hydraulic in Northwest Arid Region of China Xi’an University of TechnologyXi’anShaanxi 710048China Heilongjiang River Fisheries Research Institute Chinese Academy of Fishery SciencesHarbinHeilongjiang 150076China Gansu Fisheries Research Institute LanzhouGansu 730030China Hunan Fisheries Science Institute ChangshaHunan 410153China Yunnan Institute of Fishery Sciences Research KunmingYunnan 650111China

The genus Silurus,an important group of catfish,exhibits heterogeneous distribution in Eurasian freshwater *** group includes economically important and endangered species,thereby attracting considerable scientific *** this interest,the lack of a comprehensive phylogenetic framework impedes our understanding of the mechanisms underlying the extensive diversity found within this ***,we analyzed 89 newly sequenced and 20 previously published mitochondrial genomes(mitogenomes)from 13 morphological species to reconstruct the phylogenetic relationships,biogeographic history,and species diversity of *** phylogenetic reconstructions identified eight clades,supported by both maximum-likelihood and Bayesian ***-based species delimitation analyses yielded multiple molecular operational taxonomic units(MOTUs)in several taxa,including the Silurus asotus complex(four MOTUs)and Silurus microdorsalis(two MOTUs),suggesting that species diversity is underestimated in the genus.A reconstructed time-calibrated tree of Silurus species provided an age estimate of the most recent common ancestor of approximately 37.61 million years ago(Ma),with divergences among clades within the genus occurring between 11.56 Ma and 29.44 Ma,and divergences among MOTUs within species occurring between 3.71 Ma and 11.56 *** reconstructions suggested that the ancestral area for the genus likely encompassed China and the Korean Peninsula,with multiple inferred dispersal events to Europe and Central and Western Asia between 21.78 Ma and 26.67 Ma and to Japan between 2.51 Ma and 18.42 *** factors such as the Eocene-Oligocene extinction event,onset and intensification of the monsoon system,and glacial cycles associated with sea-level fluctuations have likely played significant roles in shaping the evolutionary history of the genus Silurus.

关键词： Maximum likelihood Bayesian inferences Ancestral area estimation Cryptic diversity Dispersal pathways Mitogenomes Sea levels

气候变迁中的身体现象学之身体心智、气候危机与人类共识

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上海交通大学学报（哲学社会科学版） 2024年第7期32卷 45-56页

作者：王积龙吴馨竹上海交通大学媒体与传播学院上海200240

漫长的气候变迁为产生人类身体心智创造了条件,人类的身体图式和身体意象也是适应气候环境变化而形成的有形状、有大小的身体心智。科学排斥可知可感的主体性视角,身体离场使得科学把同一性世界切割成功能化的碎片。人的身体就是时间的... 详细信息

漫长的气候变迁为产生人类身体心智创造了条件,人类的身体图式和身体意象也是适应气候环境变化而形成的有形状、有大小的身体心智。科学排斥可知可感的主体性视角,身体离场使得科学把同一性世界切割成功能化的碎片。人的身体就是时间的主张认为,赛博格人不具有身体内时间的连续性,是与身体无法紧密互动的外来物。身体欲望、生育能力、气候病与末日大洪水,是人造气候对具有历史性和共在性等属性的身体造成的不利影响。主体间性是身体化的主体之间的共识关系,在理论上使形成气候共识成为可能。本文观点是在身体现象学框架下推演出的初步结论。

关键词：气候变迁身体心智主体间性人类共识

Box-Behnken设计-响应面法结合G1-熵权法优化黄芪六一汤黄酮组分的提取纯化工艺

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中草药 2024年第14期55卷 4688-4699页

作者：陈方圆王继龙甘肃卫生职业学院甘肃兰州730207 甘肃省中药制药工艺工程研究中心甘肃兰州730000

目的研究黄芪六一汤(Huangqi Liuyi Decoction,HLD,黄芪-甘草6∶1组成)黄酮组分的提取和聚酰胺树脂富集纯化工艺。方法以毛蕊异黄酮葡萄糖苷、芹糖甘草苷、甘草苷、芹糖异甘草苷、芒柄花苷、甘草素、毛蕊异黄酮、异甘草素、芒柄花素9... 详细信息

目的研究黄芪六一汤(Huangqi Liuyi Decoction,HLD,黄芪-甘草6∶1组成)黄酮组分的提取和聚酰胺树脂富集纯化工艺。方法以毛蕊异黄酮葡萄糖苷、芹糖甘草苷、甘草苷、芹糖异甘草苷、芒柄花苷、甘草素、毛蕊异黄酮、异甘草素、芒柄花素9个成分为评价指标,以G1-熵权法确定各指标的组合权重,进行综合评分;采用Box-Behnken设计-响应面法(Box-Behnken design-response surface methodology,BBD-RSM)对HLD黄酮组分提取的关键影响因素乙醇体积分数、乙醇用量、提取时间、提取次数进行优化;采用单因素实验考察上样药液pH值、上样药液质量浓度、上样药液体积流量、上样量、水洗脱用量、洗脱剂乙醇体积分数、洗脱剂体积流量、洗脱剂用量等因素对黄酮组分聚酰胺富集纯化工艺的影响,采用Plackett-Burman设计(Plackett-Burman design,PBD)结合BBD-RSM筛选显著影响因素并对其进行工艺优化,比较聚酰胺树脂纯化前后各指标的含量。结果最优提取工艺为69%乙醇回流提取2次,每次10倍量乙醇提取65 min;最优纯化工艺为pH值4.8、质量浓度0.20 g/mL的上样药液以0.8 mL/min体积流量按树脂-生药1∶1的质量比上样,4个柱体积(BV)纯水以1.5 mL/min的体积流量洗脱除杂,8 BV体积分数69%乙醇以1.5 mL/min体积流量洗脱,所得黄酮组分提取物中9个指标成分含量约是纯化前的14倍。结论优选的HLD黄酮组分的提取和富集纯化工艺稳定、可行,可为进一步成药性研究和组分中药研制奠定基础。

关键词：黄芪六一汤组分中药 G1-熵权法 Box-Behnken设计-响应面法 Plackett-Burman设计聚酰胺树脂毛蕊异黄酮葡萄糖苷芹糖甘草苷甘草苷芹糖异甘草苷芒柄花苷甘草素毛蕊异黄酮异甘草素芒柄花素

自转录活性调节区测序技术在增强子发现研究中的应用

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遗传 2024年第8期46卷 589-602页

作者：王纪龙李青战廷正广西医科大学寄生虫学教研室南宁530021 广西医科大学细胞生物学教研室南宁530021 广西高校区域性疾病基础研究重点实验室(广西医科大学) 南宁530021

自转录活性调节区测序(self-transcribing active regulatory region sequencing,STARR-seq)是一种可发现并同时验证全基因组增强子活性的高通量测序方法。其原理为:将待验证序列插入质粒载体并电转入细胞中,该序列在作为增强子提高靶... 详细信息

自转录活性调节区测序(self-transcribing active regulatory region sequencing,STARR-seq)是一种可发现并同时验证全基因组增强子活性的高通量测序方法。其原理为:将待验证序列插入质粒载体并电转入细胞中,该序列在作为增强子提高靶基因转录的同时,其本身也作为靶基因被增强转录。通过对转录组进行测序,并对比未插入片段的测序结果,可获得增强子在基因组位置及活性的信息。在传统增强子研究方法中,通过对染色质开放区域和转录活性区域进行测序以预测增强子,但只能逐一验证预测结果,无法高通量验证增强子活性。STARR-seq技术解决了上述缺陷,可在对全基因组增强子高通量挖掘的同时,对其活性进行可靠的验证。自STARR-seq技术发明以来,已被广泛运用于不同物种与细胞中的增强子发现及活性验证研究。本文对传统增强子预测方法以及STARR-seq技术的基本原理、发展历史和具体运用进行了介绍,并对其发展前景进行展望,以期为后续增强子相关领域研究人员提供参考。

关键词：自转录活性区域测序增强子转录调控单核苷酸多态性

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复合微生态制剂对奶牛泌乳性能、乳品质和免疫功能的影响

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饲料工业 2024年第17期45卷 65-70页

作者：李莹亓爱杰王际龙聊城市畜牧兽医事业发展中心山东聊城252000 阳谷县畜牧兽医事业发展中心山东聊城252300 莘县畜牧兽医事业发展中心山东聊城252400

研究旨在探讨复合微生态制剂对奶牛泌乳性能、乳品质和免疫功能的影响,选择泌乳天数为240~280 d的2~3胎中国荷斯坦奶牛160头,随机分为对照组和试验A、B、C组,对照组奶牛饲喂基础日粮,试验A、B、C组奶牛分别饲喂在基础日粮中添加25、50、... 详细信息

研究旨在探讨复合微生态制剂对奶牛泌乳性能、乳品质和免疫功能的影响,选择泌乳天数为240~280 d的2~3胎中国荷斯坦奶牛160头,随机分为对照组和试验A、B、C组,对照组奶牛饲喂基础日粮,试验A、B、C组奶牛分别饲喂在基础日粮中添加25、50、75 g/(头·d)复合微生态制剂(酵母培养物+真菌酶+破壁酵母+益生菌)的日粮。试验期60 d,试验结束后采样,分别测定各组奶牛的产奶量、乳品质、乳中体细胞数、抗氧化指标及免疫功能指标,并比较分析差异显著性。结果表明:试验组奶牛的平均日产奶量、乳脂率和乳蛋白率均显著高于对照组(P0.05)。说明奶牛按50 g/(头·d)剂量饲喂复合微生态制剂,能够有效提高奶牛泌乳性能、改善乳品质、增强机体免疫功能。

关键词：复合微生态制剂奶牛泌乳性能乳品质免疫功能

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福建琅岐岛表土孢粉与植硅体组合对农业活动的指示

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海洋地质与第四纪地质 2024年第1期44卷 55-66页

作者：刘茜曾剑威王继龙戴璐于俊杰宁波大学地理与空间信息技术系宁波315211 同济大学海洋地质国家重点实验室上海200092 中国地质调查局南京地质调查中心南京210016

孢粉和植硅体是重建古人类农业景观及环境变化的重要指标,明确它们在表土中的分布规律及其与现代植被组成之间的关系对于精确解释化石孢粉和植硅体数据具有重要的意义。本研究对福建琅岐岛3种土地利用类型的22个表土样品进行了孢粉与植... 详细信息

孢粉和植硅体是重建古人类农业景观及环境变化的重要指标,明确它们在表土中的分布规律及其与现代植被组成之间的关系对于精确解释化石孢粉和植硅体数据具有重要的意义。本研究对福建琅岐岛3种土地利用类型的22个表土样品进行了孢粉与植硅体分析,基于地理信息系统和遥感技术,展示了不同类型孢粉百分比的空间分布及其与植被覆盖度间的数量对应关系。孢粉分析表明,以松属(Pinus)为代表的外来花粉普遍存在于表土样品中,这削弱了采样点周围植物的孢粉表现力,导致了果园和农田植被组成与表土孢粉组合间的巨大差异。与此同时,农业收割活动进一步降低了农田植物的花粉表现力。从遥感影像中提取的植被覆盖度数据仅与荒地上的木本植物花粉含量存在较强的相关性(R^(2)=0.7764),这显示茂密的草本植物降低了外来木本花粉的相对含量,证明了该植被类型具有良好的孢粉表现力。植硅体分析表明,表土样品含有丰富的竹亚科(Bambusoideae)、水稻(Oryza sativa)和杂草的植硅体。与孢粉指标相比,植硅体提供了更丰富的草本植物信息。

关键词：孢粉植硅体农业活动表土琅岐岛

成人Meckel憩室40例临床特征与诊断方法分析

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中华全科医师杂志 2024年第4期23卷 379-383页

作者：周艳华王继龙刘揆亮宗晔首都医科大学附属北京友谊医院消化内科、国家消化系统疾病临床医学研究中心北京100050

目的分析成人Meckel憩室的临床特征,并探讨不同影像学和内镜检查方法对成人Meckel憩室术前诊断的价值。方法该研究为回顾性研究。回顾分析2013年1月至2023年10月于首都医科大学附属北京友谊医院确诊的成人Meckel憩室患者的临床表现、诊... 详细信息

目的分析成人Meckel憩室的临床特征,并探讨不同影像学和内镜检查方法对成人Meckel憩室术前诊断的价值。方法该研究为回顾性研究。回顾分析2013年1月至2023年10月于首都医科大学附属北京友谊医院确诊的成人Meckel憩室患者的临床表现、诊断方法、治疗情况和病理结果。结果共40例患者,男性32例(80.0%),女性8例(20.0%),男女比例为4∶1,中位年龄39岁。因消化道出血、腹痛就诊者和无症状者分别占52.5%(21/40)、12.5%(5/40)和35.0%(14/40)。其中因消化道出血就诊者病程0~13年,最低血红蛋白水平为(67±14)g/L,47.6%(10/21)的患者曾输注同型悬浮红细胞治疗。腹部CT、血管造影、核素异位胃黏膜显像和核素锝标记红细胞出血显像等检查的术前诊断阳性率分别为2.6%(1/39)、0(0/7)、3/7和2/4;胶囊内镜和经肛单气囊小肠镜的诊断率分别为1/12和85.0%(17/20)。34例患者经外科手术成功治疗,术中显示憩室距回盲瓣距离20~170 cm;术后病理活组织检查结果均符合小肠憩室改变,其中7例(23.5%)病理结果显示存在异位胃黏膜,2例(5.9%)显示存在异位胰腺组织。结论成人Meckel憩室男性患者居多,多以消化道出血首发,经肛小肠镜检查诊断阳性率最高,手术是推荐治疗方法。

关键词：美克尔憩室 99m锝高锝酸钠胃黏膜单气囊小肠镜检查