检索结果-南通市图书馆

DFT Studies on Second-order Nonlinear Optical Response of Ir(C∧N)2(pic)Complexes

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2019年第2期35卷 333-339页

作者： wang huiying SHEN Zhaobin YE Jinting wang Hongqiang QIU Yongqing Institute of Functional Material Chemistry Faculty of ChemistryNortheast Normal UniversityChangchun 130024P.R.China Beijing Guohuan Environmental Technology Co. Ltd.Beijing 100029P.R.China

Density flmctional theory(DFT)was employed to calculate the geometrical structures,UV-Vis absorption spectra and second-order nonlinear optical(NLO)properties of a family of iridium(Ⅲ)complexes,which possess of different cyclometallated ligands(C∧N)and ancillary ligands[pyridme-2-carboxylate(pic)].It was found that the mo-dification of the LUMO energy levels was achieved by changing pic ligands and the energy gaps between the HOMO and LUMO were notably increased or *** addition,the degree of conjugation was significantly changed with the substituent groups varied,which led to that the first hyperpolarizabilityβcould be effectively *** the analysis of time-dependent DFT(TD-DFT)results,we predicted that these studied complexes withπ→π^*charge transfer was beneficial to the large second-order NLO ***,we hope that these studied iridium(III)complexes can be considered as versatile second-order NLO materials.

关键词： Density functional theory Iridium(III)complex Second-order nonlinear optical(NLO)property

结合图神经网络和图对比学习的半监督多图分类

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

计算机工程与应用 2025年第1期61卷 368-374页

作者：路秋霖王慧颖朱峰冉李全鑫庞俊武汉科技大学计算机科学与技术学院武汉430065 智能信息处理与实时工业系统湖北省重点实验室武汉430065 国网辽宁省电力有限公司信息通信分公司沈阳110065

多图(multi-graph,MG)是一种图袋表示模型,半监督多图分类旨在从有标记和未标记的多图中构建一个预测模型,通过高准确度预测未标记多图,在用户产品推荐、生物制药等领域有着广泛应用。现有基于机器学习的半监督多图分类主要存在两点不足... 详细信息

多图(multi-graph,MG)是一种图袋表示模型,半监督多图分类旨在从有标记和未标记的多图中构建一个预测模型,通过高准确度预测未标记多图,在用户产品推荐、生物制药等领域有着广泛应用。现有基于机器学习的半监督多图分类主要存在两点不足:(1)不能进行全自动的特征选择,过于依赖参数选择。(2)对未标记多图数据的价值未充分挖掘。因此,提出一种结合图神经网络和图对比学习的半监督多图分类方法(graph neural network combining with graph contrastive learning for semi-supervised multi-graph classification,GCSS)。一方面,分别设计从局部和全局提取特征信息的模块,并引入NN协同器(neural networks collaborator,NN collaborator)完成这两个模块的协作,自适应学习数据的特征表示进行训练;另一方面,采用图对比学习(graph contrastive learning,GCL)和半监督学习(semi-supervised learning,SSL)从两个不同学习视角来充分利用未标记多图数据,降低模型对标签等的依赖。在真实数据集上的大量实验结果验证了所提出方法的预测性能均优于基线方法。

关键词：半监督多图分类图对比学习图神经网络注意力机制

Integration, Quality Assurance, and Usage of Global Aircraft Observations in CRA

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Meteorological Research 2021年第1期35卷 1-16页

作者： Jie LIAO huiying wang Zijiang ZHOU Zhiquan LIU Lipeng JIANG Fang YUAN National Meteorological Information Center China Meteorological AdministrationBeijing 100081China National Center for Atmospheric Research CO 80301USA

This paper presents a detailed description of integration, quality assurance procedure, and usage of global aircraft observations for China's first generation global atmospheric reanalysis(CRA) product(1979–2018). An integration method named "classified integration" is developed. Aircraft observations from nine different sources are integrated into the Integrated Global Meteorological Observation Archive from Aircraft(IGMOAA), a new dataset from the National Meteorological Information Center(NMIC) of the China Meteorological Administration(CMA). IGMOAA consists of global aircraft temperature, wind, and humidity data from the surface to 100 h Pa, extending from 1973 to the present. Compared with observations assimilated in the Climate Forecast System Reanalysis(CFSR) of NCEP,the observation number of IGMOAA increased by 12.9% between 2010 and 2014, mainly as a result of adding more Chinese Aircraft Meteorological Data Relay(AMDAR) data. Complex quality control procedures for aircraft observations of NCEP are applied to detect data errors. Observations are compared with ERA-Interim reanalysis from 1979 to 2018 to investigate data quality of different types and aircraft, and subsequently to develop the blacklists for CRA. IGMOAA data have been assimilated in CRA in 2018 and are real-time updated at the CMA Data-as-a-Service(CMADaa S) platform. For CRA, the fits to observations improve over time. From 1994 to 2018, root-meansquare error(RMSE) of observations relative to CRA background decreases from 1.8 to 1.0℃ for temperature above 300 h Pa, and from 4.5 to 3 m s^(-1) for zonal wind. The RMSE for humidity appears to exhibit an apparent seasonal variation with larger errors in summer and smaller ones in winter.

关键词： aircraft observation integration quality assurance blacklist China's global atmospheric reanalysis(CRA)product

A hybrid RNA-protein biosensor for high-throughput screening of adenosylcobalamin biosynthesis

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthetic and Systems Biotechnology 2024年第3期9卷 513-521页

作者： Xia Yang huiying wang Dongqin Ding Huan Fang Huina Dong Dawei Zhang College of Biological and Pharmaceutical Sciences China Three Gorges UniversityYichangHubei443002China Tianjin Institute of Industrial Biotechnology Chinese Academy of SciencesTianjin300308China Key Laboratory of Engineering Biology for Low-Carbon Manufacturing Tianjin Institute of Industrial BiotechnologyChinese Academy of SciencesTianjin300308China University of Chinese Academy of Sciences Beijing100049China

Genetically encoded circuits have been successfully utilized to assess and characterize target variants with desirable traits from large mutant *** is an essential coenzyme that is required in many intracellular physiological reactions and is widely used in the pharmaceutical and food ***-throughput screening techniques capable of detecting adenosylcobalamin productivity and selecting superior adenosylcobalamin biosynthesis strains are critical for the creation of an effective microbial cell factory for the production of adenosylcobalamin at an industrial *** this study,we developed an RNA-protein hybrid biosensor whose input part was an endogenous RNA riboswitch to specifically respond to adenosylcobalamin,the inverter part was an orthogonal transcriptional repressor to obtain signal inversion,and the output part was a fluorescent protein to be easily *** hybrid biosensor could specifically and positively correlate adenosylcobalamin concentrations to green fluorescent protein expression levels in *** study also improved the operating concentration and dynamic range of the hybrid biosensor by systematic *** individual cell harboring the hybrid biosensor presented over 20-fold higher fluorescence intensity than the negative ***,using such a biosensor combined with fluorescence-activated cell sorting,we established a high-throughput screening platform for screening adenosylcobalamin *** study demonstrates that this platform has significant potential to quickly isolate high-productive strains to meet industrial demand and that the framework is acceptable for various metabolites.

关键词： Adenosylcobalamin Genetically encoded biosensor Riboswitch Transcriptional repressor High-throughput screening

Enhanced photocatalytic activity in Ag-nanoparticle-dispersed BaTiO3 composite thin films: Role of charge transfer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2017年第1期6卷 1-10页

作者： Suwei ZHANG Bo-ping ZHANG Shun LI Zhicheng HUANG Chushu YANG huiying wang Beijing Municipal Key Laboratory of New Energy Materials and Technologies School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China

Optical absorption and photocatalytic activity can be enhanced by surface plasmon resonance (SPR) effect,but the charge transfer (CT) mechanism between the dispersed noble metal nanoparticles (NPs) and the semiconductor matrix has been ***,we adduce a direct and strong evidence in Ag-nanoparticle-dispersed BaTiO3 (Ag/BTO) composite films through X-ray photoelectron and photoluminescence spectra which reveals the CT from BTO trapped by Ag NPs under UV light and from Ag NPs to BTO under visible *** to the broadened optical absorption and efficient CT from Ag NPs to BTO,the Ag25/BTO film manifests the optimal photocatalytic activity under the irradiation of visible light rather than UV-Vis *** work provides a helpful insight to design highly efficient plasmonic photocatalyst through considering the synergetic effect of the CT between metal and semiconductor on the enhanced photocatalytic activity.

关键词： charge transfer (CT) composite films photocatalytic activity surface plasmon resonance (SPR)

Iron adsorption engineering facilitated by Cu doping on cobalt hydroxide host with enhanced oxygen evolution reaction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2023年第2期16卷 2111-2118页

作者： Xinyu Zhang Yiwen Dong huiying wang Ziyi Zhao Wenchun Jiang Bin Dong Han Hu Chenguang Liu Yongming Chai State Key Laboratory of Heavy Oil Processing College of Chemistry and Chemical EngineeringChina University of Petroleum(East China)Qingdao 266580China College of New Energy China University of Petroleum(East China)Qingdao 266580China

Iron plays a crucial role in improving the oxygen evolution reaction(OER)activity of hydroxide *** the number of iron active sites at the solid–liquid interface is beneficial to enhancing the OER performance of catalysts but still ***,by systematic exploring the activity trends of M(OH)_(x)and Cu-M(OH)_(x)(M=Mn,Cu,Ni,Fe,and Co),we discover that the Cu doping can promote the deposition of Fe active sites on metal hydroxide and Cu-Co(OH)2 shows the most favorable iron adsorption *** loaded on a conductive substrate(cobalt foam(CF),the M-Cu-Co(OH)2/CF(Co(OH)_(2))prepared by molten salt method)exhibits an attractive low overpotential of 337 mV at 1,000 mA·cm^(−2).Using in anion exchange membrane(AEM)water electrolyzer,the single cell with M-Cu-Co(OH)_(2)/CF as anode catalyst performs a stable cell voltage of 2.02 V to reach 1,000 mA·cm^(−2)over 24 h,indicating a great application potential for actual electrolytic ***,the promoted adsorption of copper on iron provides a new perspective for further enhancing the OER activity of other metal hydroxides.

关键词： copper doping promoted Fe adsorption industrial-level current density anion exchange membrane water electrolyzer oxygen evolution reaction

Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Synthetic and Systems Biotechnology 2020年第3期5卷 200-205页

作者： Zhu Li Dongqin Ding huiying wang Linxia Liu Huan Fang Tao Chen Dawei Zhang Key Laboratory of Systems Bioengineering of the Ministry of Education School of Chemical Engineering and TechnologySynBio Research PlatformCollaborative Innovation Centre of Chemical Science and EngineeringTianjin UniversityTianjin300072China Key Laboratory of Systems Microbial Biotechnology Chinese Academy of SciencesTianjin300308China Tianjin Institute of Industrial Biotechnology Chinese Academy of SciencesTianjin300308China University of Chinese Academy of Sciences Beijing100049China

Optimizing the supply of biosynthetic precursors and cofactors is usually an effective metabolic strategy to improve the production of target ***,the combination of optimizing precursor synthesis and balancing cofactor metabolism was adopted to improve tryptophan production in Escherichia ***,glutamine synthesis was improved by expressing heterologous glutamine synthetase from Bacillus subtilis and Bacillus megaterium in the engineered Escherichia coli strain KW001,resulting in the best candidate strain *** icd and gdhA were overexpressed in TS-1,which led to the accumulation of 1.060 g/L ***,one more copy of prs was introduced on the chromosome to increase the flux of 5-phospho-α-D-ribose 1-diphosphate followed by the expression of mutated serA and thrA to increase the precursor supply of serine,resulting in the accumulation of 1.380 g/L ***,to maintain cofactor balance,sthA and pntAB,encoding transhydrogenase,were *** sufficient amounts of precursors and balanced cofactors,the engineered strain could produce 1.710 g/L tryptophan after 48 h of shake-flask fermentation,which was 2.76-times higher than the titer of the parent *** together,our results demonstrate that the combination of optimizing precursor supply and regulating cofactor metabolism is an effective approach for high-level production of *** strategies could be applied to the production of other amino acids or related derivatives.

关键词： Escherichia coli Tryptophan Metabolic precursors Cofactor supply

Study of the mechanism of cationic drug release increase coated with Sureleaseafter curing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Pharmaceutical Sciences 2013年第5期8卷 295-302页

作者： Yanting Hou huiying wang Xuezhu Zhang Meijuan Zou Gang Cheng Shenyang Pharmaceutical University No.103Wenhua RoadShenyang 110016China Northeast Pharmaceutical(Shenyang)Science&Technology Development Co.Ltd. Shenyang 110024China

This paper describes the investigation of the release mechanism of the cationic drug coated with Sureleaseafter curing compared with nonionic and anionic *** release rate of cured propafenone hydrochloride pellets coated with Sureleasewas increased significantly compared with uncured *** changes in release rate after seal-coating proved the migration of drug into the polymer *** on a comparative study of ammonia permeation tests and the impact of ammonia on drug with different properties,it was shown that the change in release of the cationic drug after curing was related to the combination of cationic drug and ammonia in Surelease.Also,the scanning electron microscopy results showed that curing and dissolution can both prevent polymer film *** coating,the evaporated ammonia combined with the cationic drug and the polymer film ***,the combined ammonia could be decomposed during curing and interrupt the coalescence of the polymer-coat,leading to increased *** an optimized process,the ammonia in the Sureleasecan be evaporated quickly and the ionization of the drug will be *** these factors can contribute to the formation of the polymer film.

关键词： Surelease Cationic drug Pellets Mechanism

Multivariate modular metabolic engineering and medium optimization for vitamin B_(12)production by Escherichia coli

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Synthetic and Systems Biotechnology 2024年第3期9卷 453-461页

作者： Feitao Chen Huan Fang Jianghua Zhao Pingtao Jiang Huina Dong Ying Zhao huiying wang Tongcun Zhang Dawei Zhang College of Biotechnology Tianjin University of Science&TechnologyTianjin300457China Tianjin Institute of Industrial Biotechnology Chinese Academy of SciencesTianjin300308China University of Chinese Academy of Science Beijing100049China Key Laboratory of Engineering Biology for Low-Carbon Manufacturing Tianjin Institute of Industrial BiotechnologyChinese Academy of SciencesTianjin 300308China National Center of Technology Innovation for Synthetic Biology Tianjin300308China

Vitamin B_(12)is a complex compound synthesized by *** industrial production of vitamin B_(12)relies on specific microbial fermentation *** has been utilized as a host for the de novo biosynthesis of vitamin B_(12),incorporating approximately 30 heterologous ***,a metabolic imbalance in the intricate pathway significantly limits vitamin B_(12)*** this study,we employed multivariate modular metabolic engineering to enhance vitamin B_(12)production in *** by manipulating two modules comprising a total of 10 genes within the vitamin B_(12)biosynthetic *** two modules were integrated into the chromosome of a chassis cell,regulated by T7,J23119,and J23106 promoters to achieve combinatorial pathway *** highest vitamin B_(12)titer was attained by engineering the two modules controlled by J23119 and T7 *** inclusion of yeast powder to the fermentation medium increased the vitamin B_(12)titer to 1.52 mg/*** enhancement was attributed to the effect of yeast powder on elevating the oxygen transfer rate and augmenting the strain’s isopropyl-β-D-1-thiogalactopyranoside(IPTG)***,vitamin B_(12)titer of 2.89 mg/L was achieved through scaled-up fermentation in a 5-liter *** strategies reported herein will expedite the development of industry-scale vitamin B_(12)production utilizing ***.

关键词： Vitamin B_(12) Multivariate modular metabolic engineering E.coli Organic nitrogen sources Fed-batch fermentation