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Photonic Sensors 2023年第3期13卷 63-76页

作者： Lingzhi MENG hongye wang Qi XIA Tingting YUAN Xiaotong ZHANG Libo YUAN The Key Lab of In-Fiber Integrated Optics Ministry Education of ChinaHarbin Engineering UniversityHarbin 150001China The Center for Smart Sensing System Julong CollegeShenzhen Technology UniversityShenzhen 518118China Photonics Research Center School of Optoelectronic EngineeringGuilin University of Electronic TechnologyGuilin 541004China

A vector bending fiber sensor based on core-by-core inscribed fiber Bragg gratings in a twin-core fiber has been proposed and experimentally *** in-fiber integrated vector bending sensor is realized by using the thermal diffusion technique to fabricate the *** characteristics of the coupler fabricated by thermal diffusion are simulated and *** inscribing fiber Bragg gratings with different reflection wavelengths in the two cores of a symmetrical twin-core fiber,the curvature sensitivity can be enhanced by tracking the wavelength difference between the fiber Bragg gratings of the two *** measured bending sensitivity of the fiber Bragg grating ranges from–161.6 pm/m^(−1) to+165.5 pm/m^(−1).The differential sensitivity of the two cores is twice that of a conventional single grating,and the temperature-induced crosstalk is also *** bending sensor proposed in this paper has the advantages of high integration,enhancing the sensitivity and two-dimensional orientation recognizability,and reducing temperature crosstalk,which can be a promising candidate for structural health monitoring or wearable artificial electronics applications.

关键词： Digital holographic tomography thermal diffusion bending sensing

Remediation of di(2-ethylhexyl)phthalate(DEHP)contaminated black soil by freeze-thaw aging biochar

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Journal of Environmental Sciences 2024年第1期135卷 681-692页

作者： Lei wang Zeyu Dou Chaoran Ma Xiaochen Jia hongye wang Wenjing Bao Lei wang Jianhua Qu Ying Zhang School of Resources and Environment Northeast Agricultural UniversityHarbin 150030China

Di(2-ethylhexyl)phthalate(DEHP),a complex structure with high toxicity,is a common organic *** study investigated the effects of fresh biochar(FBC),and freeze-thaw cycled aged biochar(FTC-BC)on DEHP-contaminated soils using a pot *** specific surface area of FBC increased from 145.20 to 303.50 m~2/g,and oxygen-containing functional groups increased from 1.26 to 1.48 mol/g after freeze-thaw cycles,greatly enhancing the adsorption of DEHP by biochar in the *** comprehensive radar chart evaluation showed that FBC and FTC-BC reduced DEHP growth stress and improved the soil *** with FBC,FTC-BC performed better in protecting the normal growth of pakchoi and improving soil *** addition,the application of biochar increased the diversity and abundance of bacteria in the DEHP-contaminated soil and changed the composition of the soil bacterial *** partial least squares path model(PLS-PM)showed that adding biochar as a soil remediation agent significantly positively impacted soil nutrients and indirectly reduced the DEHP levels in soil and plants by increasing soil microbial *** with FBC,FTC-BC creates a more satisfactory living environment for microorganisms and has a better effect on the degradation of DEHP in the *** study provides a theoretical basis for future biochar remediation of DEHP-contaminated soils in cold high-latitude regions.

关键词： DEHP Freeze-thaw cycles Biochar Soil restoration

Radiofrequency ablation of hepatocellular carcinoma: Current status,challenges, and prospects

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Liver Research 2023年第2期7卷 108-115页

作者： hongye wang Zhaorong Wu Dan Cui Yaoping Shi Bo Zhai Department of Interventional Oncology Renji HospitalShanghai Jiao Tong University School of MedicineShanghaiChina State Key Laboratory of Oncogenes and Related Genes Shanghai Cancer InstituteRenji HospitalShanghai Jiao Tong University School of MedicineShanghaiChina

Local ablation technologies, such as radiofrequency ablation (RFA), microwave ablation (MWA) andcryoablation, have become a standard treatment option for hepatocellular carcinoma (HCC) less than5 cm in size, particularly in individuals who are not candidates for hepatectomy. Except for equivalentprognosis and efficiency, RFA has various advantages over surgical excision, including a lower rate ofcomplications, a cheaper cost, more normal tissue preservation, and a shorter hospital stay. However, therate of tumor recurrence and/or distant metastasis after RFA therapy is still high. RFA has been widelyemployed in multiple cancers, large cancer, and lesion identified at “high-risk” sites in recent years, withthe advancement of ablation types and operating techniques, particularly the combined use of manytechnologies. The real value of RFA technology has been more fully *** will examine the status,progress, and problems of RFA in the treatment of HCC in this review.

关键词： Radiofrequency ablation(RFA) Hepatocellular carcinoma(HCC) Combined therapy Immunotherapy Transarterial chemoembolization(TACE) Tyrosine kinase inhibitors(TKIs)

“The red cage”:implementation of pH-responsiveness within a macrobicyclic pyridinium-based molecular host

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Organic Chemistry Frontiers 2022年第1期9卷 81-87页

作者： Pablo Cortón hongye wang Iago Neira Arturo Blanco-Gómez Elena Pazos Carlos Peinador Hao Li Marcos D.García Departamento de Química and Centro de Investigacións Científicas Avanzadas(CICA) Facultade de CienciasUniversidade da Coruña15071 A CoruñaSpain Department of Chemistry Zhejiang UniversityHangzhou 310027China

We present herein the implementation of pH-responsiveness into a new polycationic macrobicyclic structure,namely what we have termed the“red cage”.The hydrolytically-stable cryptand-like compound has been prepared in a relatively high yield in aqueous media by a kinetically-controlled hydrazone-exchange reaction,promoted by the unusual high stability of the new hydrazone CvN bonds *** organic media the macrobicycle was found not able to complex model aromatic *** buffered aqueous solutions,as a comparison,the“red cage”was found able to recognize them,but the binding was observed to be more efficient in acidic form of the cyclophane compared with its conjugate base.

关键词： bonds conjugate media

C—F Bond Insertion into Indoles with CHBr_(2)F:An Efficient Method to Synthesize Fluorinated Quinolines and Quinolones

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Chinese Journal of Chemistry 2024年第10期42卷 1128-1132页

作者： Chao Li Lei Chen hongye wang Zixi Yan Bin Lyu Weiping Lyu Changwei Jiang Dehua Lu Jiaxing Li Ning Jiao Song Song State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityXue Yuan Rd.38Beijing 100191China

A mild and practical method for synthesizing fluorinated quinoline derivatives,which have a wide range of applications in pharmaceuticals,materials,and organic synthesis,was described through C—F bond insertion into indoles using CHBr_(2)*** simple conditions,readily availability of CHBr_(2)F,as well as the versatility of the transformations make this strategy very powerful in synthesizing 3-fluoroquinoline and *** mechanistic studies reveal that bromofluorocarbene generated in-situ under basic condition was the key intermediate.

关键词： Skeleton edit Fluorocarbene Ring expansion Quinoline Quinolone

Proteome-wide epitope mapping identifies a resource of antibodies for SARS-CoV-2 detection and neutralization

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Signal Transduction and Targeted Therapy 2021年第5期6卷 1436-1438页

作者： Te Liang Mengli Cheng Fei Teng hongye wang Yongqiang Deng Jiahui Zhang Chengfeng Qin Shubin Guo Hui Zhao Xiaobo Yu State Key Laboratory of Proteomics Beijing Proteome Research CenterNational Center for Protein Sciences-Beijing(PHOENIX Center)Beijing Institute of LifeomicsBeijing 102206China Department of Virology State Key Laboratory of Pathogen and BiosecurityBeijing Institute of Microbiology and EpidemiologyAcademy of Military Medical SciencesBeijing 100071China Emergency Medicine Clinical Research Center Beijing Chao-Yang HospitalCapital Medical University&Beijing Key Laboratory of Cardiopulmonary Cerebral ResuscitationBeijing 100020China

Dear Editor,Since December 2019,the coronavirus disease 2019(COVID-19)caused by the severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)has become a worldwide pandemic.1 Significant efforts have been made to generate antibodies to help study COVID-19 pathogenesis,perform diagnostic testing,and develop treatment to neutralize SARS-CoV-2 ***,the specific sequence of amino acids recognized and bound by an antibody,the"epitope"is unknown for most *** this study,we developed a high-throughput epitope mapping platform using a peptide-based SARS-CoV-2 proteome microarray.2 to detect the binding epitopes of 57 commercial antibodies to ORFlab,nudeocapsid(N);spike(S),envelop(E),membrane(M),ORF3a,ORF6,ORF7a,and ORF8 proteins(Supplementary Table S1).

关键词： mapping antibodies epitope

Investigation on the Basic Situation and Needs of Special Children's Families——Taking Sichuan Province as an Example

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Investigation on the Basic Situation and Needs of Special Ch...

Statistical Analysis and Modified of Park-Ang Seismic Damage Model for Reinforcement Concrete Columns

3rd International Conference on Culture, Education and Economic Development of Modern Society (ICCESE 2019)

作者： Xiaoli Yang hongye wang Special Education College Leshan Normal University

In order to further understand the basic situation and needs of special children's families, taking Sichuan Province as an example, a stratified sampling method was used to conduct a questionnaire survey on 624 parents of special children in 19 counties of 14 cities in this province. The results showed that children with mental retardation and multiple disabilities had a higher family history, and multiple disabilities, mental retardation, and cerebral palsy were in poor health;one-third of special children's parents were in poor physical condition, and most of them have only received junior high school education and below;special children's families are generally poor, and their economic level is significantly related to special children's location, family history, family type, physical condition, parental physical condition, parental education and other factors;Special children's families have strong needs in economic assistance, child skill training, rehabilitation training, medical services, parental counseling, professional counseling, etc. Parents are particularly worried about their children's future survival problems.

关键词： special children family situation family needs

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Statistical Analysis and Modified of Park-Ang Seismic Damage...

Application of suppressing random noise in seismic data based on Trivashrink and DTCWT

2014海峡两岸破坏科学与材料试验学术会议暨第十二届破坏科学研讨会/第十届全国MTS材料试验学术会议

作者： wang Dongsheng SUN Zhiguo wang hongye Institute of Road and Bridge Engineering Dalian Maritime University

Performance based seismic design need to define the structural damage quantitatively and many scholars have presented some related damage evaluation ***-Ang seismic damage model is the most representative one,it considered the earthquake damage as the result of the first time of displacement exceeding and the cumulative hysteretic energy,and has a good experimental *** multiplying another energy weighted coefficient which is related to load path and can be calculated by critical ductility factor and equivalent energy factor,the modified Park-Ang seismic damage model is obtained for the seismic estimation of the reinforced concrete *** this model the critical ductility factor is calculated by the simplified equivalent plastic hinge model and is determined by the critical curvature ductility factor,this mean the proposed damage model takes into account members’response quantities and seismic damage *** on Lehman’s cyclic loading test of reinforced concrete bridge columns and the help of calculation of displacement with USCC program,it shows that the modified model have a good evaluation of the bridge pier for different column height,and the calculating of the damages at different states are more consistent with that test result for the initial concrete spall,spiral crack,and longitudinal bar buck.

关键词： Performance based seismic design Park-Ang damage model Reinforcement concrete columns Critical curvature ductility factor Simplified equivalent hinge model

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Global Geology 2014年第4期17卷 231-237页

作者： wang hongye HAN Liguo LIU Chengming WEI Yajie College of Geo-Exploration Science and Technology Jilin University

In process of seismic exploration,the noise of seismic signals produces serious interference. Conventional methods of wavelet threshold denoising cannot fully use the characteristics of seismic signals due to its limitations. There is always a certain degree of deviation between estimated value and actual value. In this study,a method of seismic data denoising is proposed,the authors use the current coefficients,the parent coefficients and the neighborhood coefficients based on dual-tree complex wavelet transform( DTCWT) and related sub-band denoising model( TrivaS hrink) to achieve the optimal estimation of shrinking factor and get the noise reduction of seismic records. It is found that the method is better than conventional methods of wavelet threshold denoising in removing random noise.

关键词： dual-tree complex wavelet transform Trivashrink threshold seismogram denoising

Study of frequency domain full waveform inversion based on Huber norm and L-BFGS algorithm

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Global Geology 2014年第4期17卷 238-242页

作者： WEI Yajie HAN Liguo DUAN Chaoran wang hongye GUO Kun College of Geo-Exploration Science and Technology Jilin University

Full waveform inversion( FWI) is a high resolution inversion method,which can reveal detailed information of the structure and lithology under complex geological background. It is limited by many kinds of noises when the method applied to the real seismic data. Based on Huber function criterion,the objective function combinates the anti-noise of L1 norm and the stability of L2 norm in theory,the authors derive the gradient formula of the Huber function by using L-BFGS algorithm for FWI. The new method is proved by synthetic seismic data with the Gaussian noise and the impulse noise. Numerical test results show that L-BFGS algorithm is applied to the frequency domain FWI with the convergence speed and high calculation accuracy,and can effectively reduce computer memory usage; and the Huber function is more robust and stable than L2 norm even with the noises.

关键词： full waveform inversion Huber function L-BFGS algorithm anti-noise